GBP5 Promotes NLRP3 inflammasome assembly and immunity in mammals

Science

Volumn 336, Issue 6080, 2012, Pages 481-485

  Shenoy, Avinash R ^a   Wellington, David A ^a,b,c   Kumar, Pradeep ^a   Kassa, Hilina ^a,d   Booth, Carmen J ^b   Cresswell, Peter ^b   MacMicking, John D ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA ACTIN; BETA INTERFERON; CRYOPYRIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANYLATE BINDING PROTEIN 5; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

BACTERIUM; IMMUNE SYSTEM; IMMUNITY; MAMMAL; PROTEIN; SECRETION;

ADAPTIVE IMMUNITY; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CYTOKINE RELEASE; CYTOSOL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC ASSOCIATION; HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; INHIBITION KINETICS; MACROPHAGE; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION;

MAMMALIA; MUS;

EID: 84860225554     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1217141     Document Type: Article

References (26)

1. K. Schroder, J. Tschopp, Cell 140, 821 (2010).
2. B. K. Davis, H. Wen, J. P.-Y. Ting, Annu. Rev. Immunol. 29, 707 (2011).
3. B.-H. Kim et al., Science 332, 717 (2011).
4. M. Shiohara et al., Biochem. Biophys. Res. Commun. 293, 1314 (2002).
5. W. O'Connor Jr., J. A. Harton, X. Zhu, M. W. Linhoff, J. P.-Y. Ting, J. Immunol. 171, 6329 (2003).
6. T. Fernandes-Alnemri, J.-W. Yu, P. Datta, J. Wu, E. S. Alnemri, Nature 458, 509 (2009).
7. F. Bauernfeind et al., J. Immunol. 187, 613 (2011).
8. D. Degrandi et al., J. Immunol. 179, 7729 (2007).
9. J. D. MacMicking, G. A. Taylor, J. D. McKinney, Science 302, 654 (2003).
10. M. G. Netea et al., Blood 113, 2324 (2009).
11. Y. Dombrowski et al., Sci. Transl. Med. 3, 82ra38 (2011).
12. P. Broz et al., J. Exp. Med. 207, 1745 (2010).
13. V. Hornung et al., Nat. Immunol. 9, 847 (2008).
14. S. Mariathasan et al., Nature 440, 228 (2006).
15. V. A. K. Rathinam et al., Nat. Immunol. 11, 395 (2010).
16. S. Kim et al., Eur. J. Immunol. 40, 1545 (2010).
17. L. Franchi et al., Nat. Immunol. 7, 576 (2006).
18. E. A. Miao et al., Nat. Immunol. 7, 569 (2006).
19. R. Zhou, A. S. Yazdi, P. Menu, J. Tschopp, Nature 469, 221 (2011).
20. K. Nakahira et al., Nat. Immunol. 12, 222 (2011).
21. P. Broz, J. von Moltke, J. W. Jones, R. E. Vance, D. M. Monack, Cell Host Microbe 8, 471 (2010).
22. A. Ghosh, G. J. K. Praefcke, L. Renault, A. Wittinghofer, C. Herrmann, Nature 440, 101 (2006).
23. S. Mariathasan et al., Nature 430, 213 (2004).
24. N. Kayagaki et al., Nature 479, 117 (2011).
25. F. Martinon, V. Pétrilli, A. Mayor, A. Tardivel, J. Tschopp, Nature 440, 237 (2006).
26. N. M. Tsuji et al., Int. Immunol. 16, 335 (2004).