Reconstituted NALP1 Inflammasome Reveals Two-Step Mechanism of Caspase-1 Activation

Molecular Cell

Volumn 25, Issue 5, 2007, Pages 713-724

  Faustin, Benjamin ^a   Lartigue, Lydia ^b   Bruey, Jean Marie ^a   Luciano, Frederic ^a   Sergienko, Eduard ^a   Bailly Maitre, Beatrice ^a   Volkmann, Niels ^a   Hanein, Dorit ^a   Rouiller, Isabelle ^a   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

CELLCYCLE; MOLIMMUNO

Indexed keywords

ADAPTOR PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LEUCINE; MULTIPROTEIN COMPLEX; MURAMYL DIPEPTIDE; NUCLEOTIDE BINDING PROTEIN; PEPTIDOGLYCAN; PROTEIN; PROTEIN ASC; PROTEIN NALP1; PROTEIN NLR; RECOMBINANT PROTEIN; RIBONUCLEOSIDE TRIPHOSPHATE; RIBONUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; BIOSENSOR; ENZYME ACTIVATION; ENZYME KINETICS; HOST RESISTANCE; INNATE IMMUNITY; NONHUMAN; OLIGOMERIZATION; PATHOGENESIS; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN SYNTHESIS;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; BACULOVIRIDAE; CASPASE 1; ENZYME ACTIVATION; INFLAMMATION; KINETICS; LIGANDS; MAGNESIUM; MICROSCOPY, ELECTRON; PROTEIN STRUCTURE, QUATERNARY;

BACTERIA (MICROORGANISMS);

EID: 33847376042     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2007.01.032     Document Type: Article

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