IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Veeranki, Sudhakar ^a   Duan, Xin ^a   Panchanathan, Ravichandran ^a,b   Liu, Hongzhu ^a   Choubey, Divaker ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; AIM2 PROTEIN; ALPHA INTERFERON; ALUMINUM POTASSIUM SULFATE; ASC PROTEIN; BETA INTERFERON; CD14 ANTIGEN; ENZYME PRECURSOR; GAMMA INTERFERON; GENE PRODUCT; IFI16 PROTEIN; INFLAMMASOME; INTERFERON; INTERLEUKIN 1BETA CONVERTING ENZYME; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); PROCASPASE 1; UNCLASSIFIED DRUG; AIM2 PROTEIN, HUMAN; ANTIINFLAMMATORY AGENT; CARRIER PROTEIN; IFI16 PROTEIN, HUMAN; NLRP3 PROTEIN, HUMAN; NUCLEAR PROTEIN; PHOSPHOPROTEIN;

AIM2 GENE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL LINE; CELL TYPE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME INACTIVATION; GENE; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IFI16 GENE; INFLAMMASOME GENE; MONOCYTE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; DRUG ANTAGONISM; IMMUNOLOGY; METABOLISM;

ANTI-INFLAMMATORY AGENTS; CARRIER PROTEINS; CASPASE 1; CELL LINE; HUMANS; INFLAMMASOMES; INTERFERON TYPE I; MONOCYTES; NUCLEAR PROTEINS; PHOSPHOPROTEINS;

EID: 80055045773     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027040     Document Type: Article

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