Pyrin Activates the ASC Pyroptosome in Response to Engagement by Autoinflammatory PSTPIP1 Mutants

Molecular Cell

Volumn 28, Issue 2, 2007, Pages 214-227

  Yu, Je Wook ^a   Fernandes Alnemri, Teresa ^a   Datta, Pinaki ^a   Wu, Jianghong ^a   Juliana, Christine ^a   Solorzano, Leobaldo ^a   McCormick, Margaret ^a   Zhang, ZhiJia ^a   Alnemri, Emad S ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

SIGNALING

Indexed keywords

CELL PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; MUTANT PROTEIN; PROTEIN PSTPIP1; PYRIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CYTOSKELETON; HUMAN; HUMAN CELL; OLIGOMERIZATION; PAPA SYNDROME; PROTEIN PROTEIN INTERACTION; PYROPTOSOME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CASPASE 1; CELL LINE; COLCHICINE; CYTOSKELETAL PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FAMILIAL MEDITERRANEAN FEVER; GENETIC VECTORS; GENOTYPE; HUMANS; IMMUNITY, NATURAL; INTERLEUKIN-1BETA; MONOCYTES; MULTIPROTEIN COMPLEXES; MUTATION; NOCODAZOLE; PHENOTYPE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RETROVIRIDAE; TRANSFECTION; TUBULIN MODULATORS;

EID: 35348934890     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2007.08.029     Document Type: Article

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