The CARD plays a critical role in ASC foci formation and inflammasome signalling

Biochemical Journal

Volumn 449, Issue 3, 2013, Pages 613-621

  Proell, Martina ^a   Gerlic, Motti ^a,b   Mace, Peter D ^a   Reed, John C ^a   Riedl, Stefan J ^a  

^a BURNHAM INSTITUTE   (United States)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Caspase 1; Caspase activation and recruitment domain (CARD); Death domain; Inflammasome; Inflammatory cytokine; Innate immunity; Leucine rich repeat containing receptor (NLR); NLR family CARD domain containing protein 4 (NLRC4); Nucleotide binding domain; Salmonella; Signalling platform formation

Indexed keywords

APOPTOSIS SPECK LIKE PROTEIN; CASPASE RECRUITMENT DOMAIN CONTAINING PROTEIN; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; OLIGOMER; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM-BINDING PROTEINS; CARD SIGNALING ADAPTOR PROTEINS; CARRIER PROTEINS; CASPASE 1; CELL LINE; CYTOSKELETAL PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; IMMUNITY, INNATE; INFLAMMASOMES; INTERLEUKIN-1BETA; MICE; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; MUTANT PROTEINS; NUCLEAR PROTEINS; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION;

SALMONELLA; SALMONELLA TYPHIMURIUM;

EID: 84872451259     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121198     Document Type: Article

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