Proteolytic processing of Nlrp1b is required for inflammasome activity

PLoS Pathogens

Volumn 8, Issue 4, 2012, Pages

  Frew, Bradley C ^a   Joag, Vineet R ^a   Mogridge, Jeremy ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTATE DEHYDROGENASE; NLRP1B PROTEIN; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; TOXIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; NALP1B PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; GENE MUTATION; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; CELL LINE; ENZYME ACTIVATION; GENETICS; METABOLISM; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE;

TOBACCO ETCH VIRUS;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CASPASE 1; CELL LINE; ENZYME ACTIVATION; INFLAMMASOMES; MICE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS;

EID: 84861215715     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002659     Document Type: Article

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