Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 8, Issue 6, 2012, Pages 987-995

  Meunier, Etienne ^a,b   Coste, Agnès ^a,b   Olagnier, David ^a,b   Authier, Hélène ^a,b   Lefèvre, Lise ^a,b   Dardenne, Christophe ^a,b   Bernad, José ^a,b   Béraud, Maryse ^a,b   Flahaut, Emmanuel ^c   Pipy, Bernard ^a,b  

^a UNIVERSITÉ PAUL SABATIER   (France)

^b Hôpital Purpan   (France)

^c INSTITUT CARNOT CIRIMAT   (France)

Author keywords

Double walled carbon nanotubes; Human monocytes; IL 1 ; Inflammation; Nlrp3 inflammasome

Indexed keywords

ADVERSE EFFECT; DOUBLE-WALLED; DOUBLE-WALLED CARBON NANOTUBES; HUMAN DISEASE; HUMAN HEALTH; HUMAN MONOCYTES; INERT PARTICLE; INFLAMMASOME; INFLAMMATION; MONOCYTES/MACROPHAGES; POTASSIUM EFFLUX; REACTIVE OXYGEN; TOLL-LIKE RECEPTORS;

ANTIGEN-ANTIBODY REACTIONS; ASBESTOS; CARBON NANOTUBES; HEALTH HAZARDS; PATHOLOGY; PHYSIOLOGY; POTASSIUM;

BODY FLUIDS;

ASBESTOS; CATHEPSIN B; CRYOPYRIN; DOUBLE WALLED NANOTUBE; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; POTASSIUM; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ACIDIFICATION; ARTICLE; CELL ACTIVATION; CELL PH; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INFLAMMATION; LYSOSOME; MONOCYTE; NORMAL HUMAN; PHAGOCYTOSIS; POTASSIUM TRANSPORT; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

CELLS, CULTURED; HUMANS; INFLAMMASOMES; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MATERIALS TESTING; MONOCYTES; NANOTUBES, CARBON;

EID: 84864106367     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2011.11.004     Document Type: Article

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