-
1
-
-
0038664382
-
Innate immunity and pathogen-host interaction
-
Basset C, Holton J, O'Mahony R, Roitt I. 2003. Innate immunity and pathogen-host interaction. Vaccine 21(Suppl. 2):S12-23
-
(2003)
Vaccine
, vol.21
, Issue.SUPPL. 2
-
-
Basset, C.1
Holton, J.2
O'Mahony, R.3
Roitt, I.4
-
2
-
-
0031050034
-
Innate immunity: Impact on the adaptive immune response
-
Medzhitov R, Janeway CA. 1997. Innate immunity: impact on the adaptive immune response. Curr. Opin. Immunol. 9:4-9
-
(1997)
Curr. Opin. Immunol
, vol.9
, pp. 4-9
-
-
Medzhitov, R.1
Janeway, C.A.2
-
3
-
-
0037066502
-
Decoding the patterns of self and nonself by the innate immune system
-
Medzhitov R, Janeway CA. 2002. Decoding the patterns of self and nonself by the innate immune system. Science 296:298-300
-
(2002)
Science
, vol.296
, pp. 298-300
-
-
Medzhitov, R.1
Janeway, C.A.2
-
4
-
-
0026791975
-
The immune system evolved to discriminate infectious nonself from noninfectious self
-
Janeway CA. 1992. The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol. Today 13:11-16
-
(1992)
Immunol. Today
, vol.13
, pp. 11-16
-
-
Janeway, C.A.1
-
5
-
-
0037066427
-
The danger model: A renewed sense of self
-
Matzinger P. 2002. The danger model: a renewed sense of self. Science 296:301-5
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
6
-
-
2942627626
-
Hydrophobicity: An ancient damage-associated molecular pattern that initiates innate immune responses
-
Seong SY, Matzinger P. 2004. Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat. Rev. Immunol. 4:469-78
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 469-478
-
-
Seong, S.Y.1
Matzinger, P.2
-
7
-
-
0035451081
-
Genomic DNA released by dying cells induces the maturation of APCs
-
Ishii KJ, Suzuki K, Coban C, Takeshita F, Itoh Y, et al. 2001. Genomic DNA released by dying cells induces the maturation of APCs. J. Immunol. 167:2602-7
-
(2001)
J. Immunol
, vol.167
, pp. 2602-2607
-
-
Ishii, K.J.1
Suzuki, K.2
Coban, C.3
Takeshita, F.4
Itoh, Y.5
-
8
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Pétrilli V, Mayor A, Tardivel A, Tschopp J. 2006. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440:237-41
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Pétrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
9
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R. 2008. Origin and physiological roles of inflammation. Nature 454:428-35
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
11
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
O'Neill LA, Bowie AG. 2007. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 7:353-64
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
12
-
-
34548459868
-
Structure and function of Toll receptors and their ligands
-
Gay NJ, Gangloff M. 2007. Structure and function of Toll receptors and their ligands. Annu. Rev. Biochem. 76:141-65
-
(2007)
Annu. Rev. Biochem
, vol.76
, pp. 141-165
-
-
Gay, N.J.1
Gangloff, M.2
-
13
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, et al. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5:730-37
-
(2004)
Nat. Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
-
14
-
-
13944253573
-
Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I
-
Sumpter R, Loo YM, Foy E, Li K, Yoneyama M, et al. 2005. Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. J. Virol. 79:2689-99
-
(2005)
J. Virol
, vol.79
, pp. 2689-2699
-
-
Sumpter, R.1
Loo, Y.M.2
Foy, E.3
Li, K.4
Yoneyama, M.5
-
15
-
-
10344259136
-
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-β promoter
-
Andrejeva J, Childs KS, Young DF, Carlos TS, Stock N, et al. 2004. The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-β promoter. Proc. Natl. Acad. Sci. USA 101:17264-69
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 17264-17269
-
-
Andrejeva, J.1
Childs, K.S.2
Young, D.F.3
Carlos, T.S.4
Stock, N.5
-
16
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, et al. 2005. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437:1167-72
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
-
17
-
-
30544444850
-
CARD games between virus and host get a new player
-
Johnson CL, Gale M. 2006. CARD games between virus and host get a new player. Trends Immunol. 27:1-4
-
(2006)
Trends Immunol
, vol.27
, pp. 1-4
-
-
Johnson, C.L.1
Gale, M.2
-
18
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ. 2005. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF 3. Cell 122:669-82
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
19
-
-
22444433175
-
NLRs join TLRs as innate sensors of pathogens
-
Martinon F, Tschopp J. 2005. NLRs join TLRs as innate sensors of pathogens. Trends Immunol. 26:447-54
-
(2005)
Trends Immunol
, vol.26
, pp. 447-454
-
-
Martinon, F.1
Tschopp, J.2
-
20
-
-
23044452084
-
NACHT-LRR proteins (NLRs) in bacterial infection and immunity
-
Kufer T, Fritz JH, Philpott DJ. 2005. NACHT-LRR proteins (NLRs) in bacterial infection and immunity. Trends Microbiol. 13:381-88
-
(2005)
Trends Microbiol
, vol.13
, pp. 381-388
-
-
Kufer, T.1
Fritz, J.H.2
Philpott, D.J.3
-
21
-
-
49249092223
-
The leucine-rich repeat structure
-
Bella J, Hindle KL, McEwan PA, Lovell SC. 2008. The leucine-rich repeat structure. Cell Mol. Life Sci. 65(15):2307-33
-
(2008)
Cell Mol. Life Sci
, vol.65
, Issue.15
, pp. 2307-2333
-
-
Bella, J.1
Hindle, K.L.2
McEwan, P.A.3
Lovell, S.C.4
-
22
-
-
42349090335
-
Structural basis of Toll-like receptor 3 signaling with double-stranded RNA
-
Liu L, Botos I, Wang Y, Leonard JN, Shiloach J, et al. 2008. Structural basis of Toll-like receptor 3 signaling with double-stranded RNA. Science 320:379-81
-
(2008)
Science
, vol.320
, pp. 379-381
-
-
Liu, L.1
Botos, I.2
Wang, Y.3
Leonard, J.N.4
Shiloach, J.5
-
23
-
-
34548605445
-
Two modes of ligand recognition by TLRs
-
Brodsky I, Medzhitov R. 2007. Two modes of ligand recognition by TLRs. Cell 130:979-81
-
(2007)
Cell
, vol.130
, pp. 979-981
-
-
Brodsky, I.1
Medzhitov, R.2
-
24
-
-
4644247731
-
STAND, a class of P-loop NTPases including animal and plant regulators of programmed cell death: Multiple, complex domain architectures, unusual phyletic patterns, and evolution by horizontal gene transfer
-
Leipe DD, Koonin EV, Aravind L. 2004. STAND, a class of P-loop NTPases including animal and plant regulators of programmed cell death: multiple, complex domain architectures, unusual phyletic patterns, and evolution by horizontal gene transfer. J. Mol. Biol. 343:1-28
-
(2004)
J. Mol. Biol
, vol.343
, pp. 1-28
-
-
Leipe, D.D.1
Koonin, E.V.2
Aravind, L.3
-
25
-
-
2542457495
-
Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
-
Martinon F, Tschopp J. 2004. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117:561-74
-
(2004)
Cell
, vol.117
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
26
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
-
Faustin B, Lartigue L, Bruey JM, Luciano F, Sergienko E, et al. 2007. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. Mol. Cell 25:713-24
-
(2007)
Mol. Cell
, vol.25
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.M.3
Luciano, F.4
Sergienko, E.5
-
27
-
-
34247842740
-
The death domain superfamily in intracellular signaling of apoptosis and inflammation
-
Park HH, Lo YC, Lin SC, Wang L, Yang JK, Wu H. 2007. The death domain superfamily in intracellular signaling of apoptosis and inflammation. Annu. Rev. Immunol. 25:561-86
-
(2007)
Annu. Rev. Immunol
, vol.25
, pp. 561-586
-
-
Park, H.H.1
Lo, Y.C.2
Lin, S.C.3
Wang, L.4
Yang, J.K.5
Wu, H.6
-
28
-
-
0035895540
-
Apoptotic molecular machinery: Vastly increased complexity in vertebrates revealed by genome comparisons
-
Aravind L, Dixit VM, Koonin EV. 2001. Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons. Science 291:1279-84
-
(2001)
Science
, vol.291
, pp. 1279-1284
-
-
Aravind, L.1
Dixit, V.M.2
Koonin, E.V.3
-
30
-
-
0038624558
-
NODs: Intracellular proteins involved in inflammation and apoptosis
-
Inohara N, Nuñez G. 2003. NODs: intracellular proteins involved in inflammation and apoptosis. Nat. Rev. Immunol. 3:371-82
-
(2003)
Nat. Rev. Immunol
, vol.3
, pp. 371-382
-
-
Inohara, N.1
Nuñez, G.2
-
31
-
-
34447132506
-
CATERPILLER (NLR) family members as positive and negative regulators of inflammatory responses
-
Lich JD, Ting JP. 2007. CATERPILLER (NLR) family members as positive and negative regulators of inflammatory responses. Proc. Am. Thoracic Soc. 4:263-66
-
(2007)
Proc. Am. Thoracic Soc
, vol.4
, pp. 263-266
-
-
Lich, J.D.1
Ting, J.P.2
-
32
-
-
44349171085
-
The Nod-like receptor (NLR) family: A tale of similarities and differences
-
Proell M, Riedl S, Fritz J, Rojas A, Schwarzenbacher R. 2008. The Nod-like receptor (NLR) family: a tale of similarities and differences. PLoS ONE 3:e2119
-
(2008)
PLoS ONE
, vol.3
-
-
Proell, M.1
Riedl, S.2
Fritz, J.3
Rojas, A.4
Schwarzenbacher, R.5
-
33
-
-
33845497181
-
Inflammatory caspases and inflammasomes: Master switches of inflammation
-
Martinon F, Tschopp J. 2007. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ. 14:10-22
-
(2007)
Cell Death Differ
, vol.14
, pp. 10-22
-
-
Martinon, F.1
Tschopp, J.2
-
34
-
-
0035064073
-
The bare lymphocyte syndrome and the regulation of MHC expression
-
Reith W, Mach B. 2001. The bare lymphocyte syndrome and the regulation of MHC expression. Annu. Rev. Immunol. 19:331-73
-
(2001)
Annu. Rev. Immunol
, vol.19
, pp. 331-373
-
-
Reith, W.1
Mach, B.2
-
36
-
-
38749097018
-
NLRX1 is a regulator of mitochondrial antiviral immunity
-
Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, et al. 2008. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature 451:573-77
-
(2008)
Nature
, vol.451
, pp. 573-577
-
-
Moore, C.B.1
Bergstralh, D.T.2
Duncan, J.A.3
Lei, Y.4
Morrison, T.E.5
-
37
-
-
40249111682
-
NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production
-
9:293-300
-
Tattoli I, Carneiro LA, Jéhanno M, Magalhaes JG, Shu Y, et al. 2008. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production. EMBO Rep. 9:293-300
-
(2008)
EMBO Rep
-
-
Tattoli, I.1
Carneiro, L.A.2
Jéhanno, M.3
Magalhaes, J.G.4
Shu, Y.5
-
38
-
-
45549092412
-
NAIP and Ipaf control Legionella pneumophila replication in human cells
-
Vinzing M, Eitel J, Lippmann J, Hocke AC, Zahlten J, et al. 2008. NAIP and Ipaf control Legionella pneumophila replication in human cells. J. Immunol. 180:6808-15
-
(2008)
J. Immunol
, vol.180
, pp. 6808-6815
-
-
Vinzing, M.1
Eitel, J.2
Lippmann, J.3
Hocke, A.C.4
Zahlten, J.5
-
39
-
-
34247574122
-
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response
-
Kummer JA, Broekhuizen R, Everett H, Agostini L, Kuijk L, et al. 2007. Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J. Histochem. Cytochem. 55:443-52
-
(2007)
J. Histochem. Cytochem
, vol.55
, pp. 443-452
-
-
Kummer, J.A.1
Broekhuizen, R.2
Everett, H.3
Agostini, L.4
Kuijk, L.5
-
40
-
-
37549066934
-
Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death
-
McCall SH, Sahraei M, Young AB, Worley CS, Duncan JA, et al. 2008. Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death. J. Bone Miner. Res. 23:30-40
-
(2008)
J. Bone Miner. Res
, vol.23
, pp. 30-40
-
-
McCall, S.H.1
Sahraei, M.2
Young, A.B.3
Worley, C.S.4
Duncan, J.A.5
-
41
-
-
0035958867
-
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
-
Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES. 2001. Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J. Biol. Chem. 276:28309-13
-
(2001)
J. Biol. Chem
, vol.276
, pp. 28309-28313
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Tnani, M.3
Razmara, M.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
42
-
-
0034142264
-
The neuronal apoptosis inhibitory protein (Naip) is expressed in macrophages and is modulated after phagocytosis and during intracellular infection with Legionella pneumophila
-
Diez E, Yaraghi Z, MacKenzie A, Gros P. 2000. The neuronal apoptosis inhibitory protein (Naip) is expressed in macrophages and is modulated after phagocytosis and during intracellular infection with Legionella pneumophila. J. Immunol. 164:1470-77
-
(2000)
J. Immunol
, vol.164
, pp. 1470-1477
-
-
Diez, E.1
Yaraghi, Z.2
MacKenzie, A.3
Gros, P.4
-
43
-
-
59349101210
-
Identification of oocyte-selective NLRP genes in rhesus macaque monkeys (Macaca mulatta)
-
McDaniel P, Wu X. 2008. Identification of oocyte-selective NLRP genes in rhesus macaque monkeys (Macaca mulatta). Mol. Reprod. Dev. 76:151-59
-
(2008)
Mol. Reprod. Dev
, vol.76
, pp. 151-159
-
-
McDaniel, P.1
Wu, X.2
-
44
-
-
34548670965
-
Inflammasomes in inflammatory disorders: The role of TLRs and their interactions with NLRs
-
Becker CE, O'Neill LA. 2007. Inflammasomes in inflammatory disorders: the role of TLRs and their interactions with NLRs. Semin. Immunopathol. 29:239-48
-
(2007)
Semin. Immunopathol
, vol.29
, pp. 239-248
-
-
Becker, C.E.1
O'Neill, L.A.2
-
45
-
-
40149104095
-
Plant NB-LRR immune receptors: From recognition to transcriptional reprogramming
-
Caplan J, Padmanabhan M, Dinesh-Kumar SP. 2008. Plant NB-LRR immune receptors: from recognition to transcriptional reprogramming. Cell Host Microbe 3:126-35
-
(2008)
Cell Host Microbe
, vol.3
, pp. 126-135
-
-
Caplan, J.1
Padmanabhan, M.2
Dinesh-Kumar, S.P.3
-
46
-
-
38049074926
-
Global expression analysis of nucleotide binding site-leucine rich repeat-encoding and related genes in Arabidopsis
-
Tan X, Meyers BC, Kozik A, West MA, Morgante M, et al. 2007. Global expression analysis of nucleotide binding site-leucine rich repeat-encoding and related genes in Arabidopsis. BMC Plant Biol. 7:56
-
(2007)
BMC Plant Biol
, vol.7
, pp. 56
-
-
Tan, X.1
Meyers, B.C.2
Kozik, A.3
West, M.A.4
Morgante, M.5
-
47
-
-
35148827341
-
Elicitors, effectors, and R genes: The new paradigm and a lifetime supply of questions
-
Bent AF, Mackey D. 2007. Elicitors, effectors, and R genes: the new paradigm and a lifetime supply of questions. Annu. Rev. Phytopathol. 45:399-436
-
(2007)
Annu. Rev. Phytopathol
, vol.45
, pp. 399-436
-
-
Bent, A.F.1
Mackey, D.2
-
48
-
-
27144540463
-
Are innate immune signaling pathways in plants and animals conserved?
-
Ausubel F. 2005. Are innate immune signaling pathways in plants and animals conserved? Nat. Immunol. 6:973-79
-
(2005)
Nat. Immunol
, vol.6
, pp. 973-979
-
-
Ausubel, F.1
-
49
-
-
34547520329
-
Tracing the ancient origins of plant innate immunity
-
Staal J, Dixelius C. 2007. Tracing the ancient origins of plant innate immunity. Trends Plant Sci. 12:334-42
-
(2007)
Trends Plant Sci
, vol.12
, pp. 334-342
-
-
Staal, J.1
Dixelius, C.2
-
50
-
-
0026585351
-
The birth of immunology. III. The fate of the phagocytosis theory
-
Tauber AI. 1992. The birth of immunology. III. The fate of the phagocytosis theory. Cell Immunol. 139:505-30
-
(1992)
Cell Immunol
, vol.139
, pp. 505-530
-
-
Tauber, A.I.1
-
51
-
-
33751549306
-
The immune gene repertoire encoded in the purple sea urchin genome
-
Hibino T, Loza-Coll M, Messier C, Majeske AJ, Cohen AH, et al. 2006. The immune gene repertoire encoded in the purple sea urchin genome. Dev. Biol. 300:349-65
-
(2006)
Dev. Biol
, vol.300
, pp. 349-365
-
-
Hibino, T.1
Loza-Coll, M.2
Messier, C.3
Majeske, A.J.4
Cohen, A.H.5
-
52
-
-
33750980112
-
Genomic insights into the immune system of the sea urchin
-
Rast JP, Smith LC, Loza-Coll M, Hibino T, Litman GW. 2006. Genomic insights into the immune system of the sea urchin. Science 314:952-56
-
(2006)
Science
, vol.314
, pp. 952-956
-
-
Rast, J.P.1
Smith, L.C.2
Loza-Coll, M.3
Hibino, T.4
Litman, G.W.5
-
53
-
-
40949159815
-
A genomic view of the NOD-like receptor family in teleost fish: Identification of a novel NLR subfamily in zebrafish
-
Laing K, Purcell M, Winton J, Hansen J. 2008. A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish. BMC Evol. Biol. 8:42
-
(2008)
BMC Evol. Biol
, vol.8
, pp. 42
-
-
Laing, K.1
Purcell, M.2
Winton, J.3
Hansen, J.4
-
54
-
-
42149124615
-
Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish
-
Stein C, Caccamo M, Laird G, Leptin M. 2007. Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish. Genome Biol. 8:R251
-
(2007)
Genome Biol
, vol.8
-
-
Stein, C.1
Caccamo, M.2
Laird, G.3
Leptin, M.4
-
55
-
-
33745631232
-
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β production
-
Chae JJ, Wood G, Masters SL, Richard K, Park G, et al. 2006. The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β production. Proc. Natl. Acad. Sci. USA 103:9982-87
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 9982-9987
-
-
Chae, J.J.1
Wood, G.2
Masters, S.L.3
Richard, K.4
Park, G.5
-
56
-
-
34547138176
-
The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing
-
Papin S, Cuenin S, Agostini L, Martinon F, Werner S, et al. 2007. The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing. Cell Death Differ. 14:1457-66
-
(2007)
Cell Death Differ
, vol.14
, pp. 1457-1466
-
-
Papin, S.1
Cuenin, S.2
Agostini, L.3
Martinon, F.4
Werner, S.5
-
57
-
-
0036066765
-
The role of lineage-specific gene family expansion in the evolution of Eukaryotes
-
Lespinet O, Wolf YI, Koonin EV, Aravind L. 2002. The role of lineage-specific gene family expansion in the evolution of Eukaryotes. Genome Res. 12:1048-59
-
(2002)
Genome Res
, vol.12
, pp. 1048-1059
-
-
Lespinet, O.1
Wolf, Y.I.2
Koonin, E.V.3
Aravind, L.4
-
58
-
-
0033532091
-
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-κB
-
Bertin J, Nir WJ, Fischer CM, Tayber OV, Errada PR, et al. 1999. Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-κB. J. Biol. Chem. 274:12955-58
-
(1999)
J. Biol. Chem
, vol.274
, pp. 12955-12958
-
-
Bertin, J.1
Nir, W.J.2
Fischer, C.M.3
Tayber, O.V.4
Errada, P.R.5
-
59
-
-
0033591330
-
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-κB
-
Inohara N, Koseki T, del Peso L, Hu Y, Yee C, et al. 1999. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-κB. J. Biol. Chem. 274:14560-67
-
(1999)
J. Biol. Chem
, vol.274
, pp. 14560-14567
-
-
Inohara, N.1
Koseki, T.2
del Peso, L.3
Hu, Y.4
Yee, C.5
-
60
-
-
34548688429
-
The Nodosome: Nod1 and Nod2 control bacterial infections and inflammation
-
Tattoli I, Travassos L, Carneiro LA, Magalhaes J, Girardin S. 2007. The Nodosome: Nod1 and Nod2 control bacterial infections and inflammation. Semin. Immunopathol. 29:289-301
-
(2007)
Semin. Immunopathol
, vol.29
, pp. 289-301
-
-
Tattoli, I.1
Travassos, L.2
Carneiro, L.A.3
Magalhaes, J.4
Girardin, S.5
-
61
-
-
33846469538
-
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens
-
Hsu Y, Zhang Y, You Y, Wang D, Li H, et al. 2007. The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nat. Immunol. 8:198-205
-
(2007)
Nat. Immunol
, vol.8
, pp. 198-205
-
-
Hsu, Y.1
Zhang, Y.2
You, Y.3
Wang, D.4
Li, H.5
-
62
-
-
20144382924
-
Peptidoglycan signaling in innate immunity and inflammatory disease
-
Mcdonald C, Inohara N, Nunez G. 2005. Peptidoglycan signaling in innate immunity and inflammatory disease. J. Biol. Chem. 280:20177-80
-
(2005)
J. Biol. Chem
, vol.280
, pp. 20177-20180
-
-
Mcdonald, C.1
Inohara, N.2
Nunez, G.3
-
63
-
-
3442893287
-
Mini-review: The role of peptidoglycan recognition in innate immunity
-
Girardin SE, Philpott DJ. 2004. Mini-review: the role of peptidoglycan recognition in innate immunity. Eur. J. Immunol. 34:1777-82
-
(2004)
Eur. J. Immunol
, vol.34
, pp. 1777-1782
-
-
Girardin, S.E.1
Philpott, D.J.2
-
64
-
-
9244245293
-
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
-
Viala J, Chaput C, Boneca I, Cardona A, Girardin SE, et al. 2004. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat. Immunol. 5:1166-74
-
(2004)
Nat. Immunol
, vol.5
, pp. 1166-1174
-
-
Viala, J.1
Chaput, C.2
Boneca, I.3
Cardona, A.4
Girardin, S.E.5
-
65
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, et al. 2005. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307:731-34
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
-
66
-
-
34247116430
-
How NOD2 mutations predispose to Crohn's disease?
-
Vignal C, Singer E, Peyrin-Biroulet L, Desreumaux P, Chamaillard M. 2007. How NOD2 mutations predispose to Crohn's disease? Microbes Infect. 9:658-63
-
(2007)
Microbes Infect
, vol.9
, pp. 658-663
-
-
Vignal, C.1
Singer, E.2
Peyrin-Biroulet, L.3
Desreumaux, P.4
Chamaillard, M.5
-
67
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
Tanabe T, Chamaillard M, Ogura Y, Zhu L, Qiu S, et al. 2004. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. EMBO J. 23:1587-97
-
(2004)
EMBO J
, vol.23
, pp. 1587-1597
-
-
Tanabe, T.1
Chamaillard, M.2
Ogura, Y.3
Zhu, L.4
Qiu, S.5
-
68
-
-
45549093755
-
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide
-
Hsu LC, Ali SR, McGillivray S, Tseng PH, Mariathasan S, et al. 2008. A NOD2-NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc. Natl. Acad. Sci. USA 105:7803-8
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 7803-7808
-
-
Hsu, L.C.1
Ali, S.R.2
McGillivray, S.3
Tseng, P.H.4
Mariathasan, S.5
-
69
-
-
34347382756
-
MDP-induced interleukin-1β processing requires Nod2 and CIAS1/NALP3
-
Pan Q, Mathison J, Fearns C, Kravchenko VV, Da Silva Correia J, et al. 2007. MDP-induced interleukin-1β processing requires Nod2 and CIAS1/NALP3. J. Leukoc. Biol. 82:177-83
-
(2007)
J. Leukoc. Biol
, vol.82
, pp. 177-183
-
-
Pan, Q.1
Mathison, J.2
Fearns, C.3
Kravchenko, V.V.4
Da Silva Correia, J.5
-
70
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-1β
-
Martinon F, Burns K, Tschopp J. 2002. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-1β. Mol. Cell 10:417-26
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
71
-
-
0033596980
-
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
Zou H, Li Y, Liu X, Wang X. 1999. An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274:11549-56
-
(1999)
J. Biol. Chem
, vol.274
, pp. 11549-11556
-
-
Zou, H.1
Li, Y.2
Liu, X.3
Wang, X.4
-
72
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen GM. 1997. Caspases: the executioners of apoptosis. Biochem. J. 326(Pt. 1):1-16
-
(1997)
Biochem. J
, vol.326
, Issue.PART. 1
, pp. 1-16
-
-
Cohen, G.M.1
-
73
-
-
10644282148
-
The protein structures that shape caspase activity, specificity, activation and inhibition
-
Fuentes-Prior P, Salvesen GS. 2004. The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem. J. 384:201-32
-
(2004)
Biochem. J
, vol.384
, pp. 201-232
-
-
Fuentes-Prior, P.1
Salvesen, G.S.2
-
75
-
-
33749131042
-
The inflammatory caspases: Key players in the host response to pathogenic invasion and sepsis
-
Nadiri A, Wolinski MK, Saleh M. 2006. The inflammatory caspases: key players in the host response to pathogenic invasion and sepsis. J. Immunol. 177:4239-45
-
(2006)
J. Immunol
, vol.177
, pp. 4239-4245
-
-
Nadiri, A.1
Wolinski, M.K.2
Saleh, M.3
-
76
-
-
34548687694
-
NALP inflammasomes: A central role in innate immunity
-
Martinon F, Gaide O, Pétrilli V, Mayor A, Tschopp J. 2007. NALP inflammasomes: a central role in innate immunity. Semin. Immunopathol. 29:213-29
-
(2007)
Semin. Immunopathol
, vol.29
, pp. 213-229
-
-
Martinon, F.1
Gaide, O.2
Pétrilli, V.3
Mayor, A.4
Tschopp, J.5
-
77
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, et al. 2004. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430:213-18
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
-
78
-
-
1642285783
-
NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
Agostini L, Burns K, McDermott MF, Hawkins PN, Tschopp J. 2004. NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20:319-25
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Burns, K.2
McDermott, M.F.3
Hawkins, P.N.4
Tschopp, J.5
-
79
-
-
34249941913
-
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling
-
Duncan JA, Bergstralh DT, Wang Y, Willingham SB, Ye Z, et al. 2007. Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling. Proc. Natl. Acad. Sci. USA 104:8041-46
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 8041-8046
-
-
Duncan, J.A.1
Bergstralh, D.T.2
Wang, Y.3
Willingham, S.B.4
Ye, Z.5
-
80
-
-
18844362879
-
Nucleotide binding to CARD12 and its role in CARD12-mediated caspase-1 activation
-
Lu C, Wang A, Wang L, Dorsch M, Ocain TD, Xu Y. 2005. Nucleotide binding to CARD12 and its role in CARD12-mediated caspase-1 activation. Biochem. Biophys. Res. Commun. 331:1114-19
-
(2005)
Biochem. Biophys. Res. Commun
, vol.331
, pp. 1114-1119
-
-
Lu, C.1
Wang, A.2
Wang, L.3
Dorsch, M.4
Ocain, T.D.5
Xu, Y.6
-
81
-
-
34247265509
-
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
-
Mayor A, Martinon F, De Smedt T, Pétrilli V, Tschopp J. 2007. A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nat. Immunol. 8:497-503
-
(2007)
Nat. Immunol
, vol.8
, pp. 497-503
-
-
Mayor, A.1
Martinon, F.2
De Smedt, T.3
Pétrilli, V.4
Tschopp, J.5
-
83
-
-
38949194974
-
Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol
-
Chapelsky S, Batty S, Frost M, Mogridge J. 2008. Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol. PLoS ONE 3:e1421
-
(2008)
PLoS ONE
, vol.3
-
-
Chapelsky, S.1
Batty, S.2
Frost, M.3
Mogridge, J.4
-
85
-
-
36949007646
-
Intracellular NOD-like receptors in innate immunity, infection and disease
-
Franchi L, Park JH, Shaw MH, Marina-Garcia N, Chen G, et al. 2008. Intracellular NOD-like receptors in innate immunity, infection and disease. Cell Microbiol. 10:1-8
-
(2008)
Cell Microbiol
, vol.10
, pp. 1-8
-
-
Franchi, L.1
Park, J.H.2
Shaw, M.H.3
Marina-Garcia, N.4
Chen, G.5
-
86
-
-
36248957578
-
Orchestration of pathogen recognition by inflammasome diversity: Variations on a common theme
-
Martinon F. 2007. Orchestration of pathogen recognition by inflammasome diversity: variations on a common theme. Eur. J. Immunol. 37:3003-6
-
(2007)
Eur. J. Immunol
, vol.37
, pp. 3003-3006
-
-
Martinon, F.1
-
87
-
-
0028201732
-
Tolerance, danger, and the extended family
-
Matzinger P. 1994. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12:991-1045
-
(1994)
Annu. Rev. Immunol
, vol.12
, pp. 991-1045
-
-
Matzinger, P.1
-
88
-
-
41749104586
-
The inflammatory response to cell death
-
Rock KL, Kono H. 2008. The inflammatory response to cell death. Annu. Rev. Pathol. 3:99-126
-
(2008)
Annu. Rev. Pathol
, vol.3
, pp. 99-126
-
-
Rock, K.L.1
Kono, H.2
-
89
-
-
41149118513
-
How dying cells alert the immune system to danger
-
Kono H, Rock KL. 2008. How dying cells alert the immune system to danger. Nat. Rev. Immunol. 8:279-89
-
(2008)
Nat. Rev. Immunol
, vol.8
, pp. 279-289
-
-
Kono, H.1
Rock, K.L.2
-
91
-
-
0037205304
-
Plant immunity and film noir: What gumshoe detectives can teach us about plant-pathogen interactions
-
Schneider DS. 2002. Plant immunity and film noir: what gumshoe detectives can teach us about plant-pathogen interactions. Cell 109:537-40
-
(2002)
Cell
, vol.109
, pp. 537-540
-
-
Schneider, D.S.1
-
92
-
-
0002928890
-
Identification of a monocyte specific preinterleukin 1 β convertase activity
-
Kostura MJ, Tocci MJ, Limjuco G, Chin J, Cameron P, et al. 1989. Identification of a monocyte specific preinterleukin 1 β convertase activity. Proc. Natl. Acad. Sci. USA 86:5227-31
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5227-5231
-
-
Kostura, M.J.1
Tocci, M.J.2
Limjuco, G.3
Chin, J.4
Cameron, P.5
-
93
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Pétrilli V, Papin S, Dostert C, Mayor A, Tschopp J. 2007. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14:1583-89
-
(2007)
Cell Death Differ
, vol.14
, pp. 1583-1589
-
-
Pétrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Tschopp, J.5
-
96
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, et al. 2006. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440:228-32
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
-
97
-
-
33644985564
-
Critical role for NALP3/CIAS1/cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, et al. 2006. Critical role for NALP3/CIAS1/cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24:317-27
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
-
98
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
Kanneganti TD, Ozören N, Body-Malapel M, Amer A, Park JH, et al. 2006. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 440:233-36
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozören, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
-
99
-
-
33947621054
-
Extracellular NAD and ATP: Partners in immune cell modulation
-
Haag F, Adriouch S, Braß A, Jung C, Möller S, et al. 2007. Extracellular NAD and ATP: partners in immune cell modulation. Purinergic Signal 3:71-81
-
(2007)
Purinergic Signal
, vol.3
, pp. 71-81
-
-
Haag, F.1
Adriouch, S.2
Braß, A.3
Jung, C.4
Möller, S.5
-
100
-
-
34250155915
-
Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury
-
Eckle T, Füllbier L, Wehrmann M, Khoury J, Mittelbronn M, et al. 2007. Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury. J. Immunol. 178:8127-37
-
(2007)
J. Immunol
, vol.178
, pp. 8127-8137
-
-
Eckle, T.1
Füllbier, L.2
Wehrmann, M.3
Khoury, J.4
Mittelbronn, M.5
-
101
-
-
0034125277
-
Advances in signalling by extracellular nucleotides: The role and transduction mechanisms of P2Y receptors
-
Communi D, Janssens R, Suarez-Huerta N, Robaye B, Boeynaems JM. 2000. Advances in signalling by extracellular nucleotides: the role and transduction mechanisms of P2Y receptors. Cell Signal. 12:351-60
-
(2000)
Cell Signal
, vol.12
, pp. 351-360
-
-
Communi, D.1
Janssens, R.2
Suarez-Huerta, N.3
Robaye, B.4
Boeynaems, J.M.5
-
102
-
-
0037291462
-
ATP as a signaling molecule: The exocrine focus
-
Novak I. 2003. ATP as a signaling molecule: the exocrine focus. News Physiol. Sci. 18:12-17
-
(2003)
News Physiol. Sci
, vol.18
, pp. 12-17
-
-
Novak, I.1
-
103
-
-
33748946239
-
Release of small transmitters through kiss-and-run fusion pores in rat pancreatic beta cells
-
MacDonald PE, Braun M, Galvanovskis J, Rorsman P. 2006. Release of small transmitters through kiss-and-run fusion pores in rat pancreatic beta cells. Cell Metab. 4:283-90
-
(2006)
Cell Metab
, vol.4
, pp. 283-290
-
-
MacDonald, P.E.1
Braun, M.2
Galvanovskis, J.3
Rorsman, P.4
-
104
-
-
0033516461
-
Salivary histatin 5 induces nonlytic release of ATP from Candida albicans leading to cell death
-
Koshlukova SE, Lloyd TL, Araujo MW, Edgerton M. 1999. Salivary histatin 5 induces nonlytic release of ATP from Candida albicans leading to cell death. J. Biol. Chem. 274:18872-79
-
(1999)
J. Biol. Chem
, vol.274
, pp. 18872-18879
-
-
Koshlukova, S.E.1
Lloyd, T.L.2
Araujo, M.W.3
Edgerton, M.4
-
105
-
-
0033601241
-
ATP treatment of human monocytes promotes caspase-1 maturation and externalization
-
Laliberte RE, Eggler J, Gabel CA. 1999. ATP treatment of human monocytes promotes caspase-1 maturation and externalization. J. Biol. Chem. 274:36944-51
-
(1999)
J. Biol. Chem
, vol.274
, pp. 36944-36951
-
-
Laliberte, R.E.1
Eggler, J.2
Gabel, C.A.3
-
106
-
-
34247118826
-
Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling
-
Kanneganti TD, Lamkanfi M, Kim YG, Chen G, Park JH, et al. 2007. Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity 26:433-43
-
(2007)
Immunity
, vol.26
, pp. 433-443
-
-
Kanneganti, T.D.1
Lamkanfi, M.2
Kim, Y.G.3
Chen, G.4
Park, J.H.5
-
108
-
-
45849102043
-
ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way
-
Piccini A, Carta S, Tassi S, Lasiglié D, Fossati G, Rubartelli A. 2008. ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way. Proc. Natl. Acad. Sci. USA 105:8067-72
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 8067-8072
-
-
Piccini, A.1
Carta, S.2
Tassi, S.3
Lasiglié, D.4
Fossati, G.5
Rubartelli, A.6
-
109
-
-
7944231451
-
ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules
-
Yamamoto M, Yaginuma K, Tsutsui H, Sagara J, Guan X, et al. 2004. ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules. Genes Cells 9:1055-67
-
(2004)
Genes Cells
, vol.9
, pp. 1055-1067
-
-
Yamamoto, M.1
Yaginuma, K.2
Tsutsui, H.3
Sagara, J.4
Guan, X.5
-
110
-
-
34547655975
-
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells
-
Idzko M, Hammad H, van Nimwegen M, Kool M, Willart MA, et al. 2007. Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nat. Med. 13:913-19
-
(2007)
Nat. Med
, vol.13
, pp. 913-919
-
-
Idzko, M.1
Hammad, H.2
van Nimwegen, M.3
Kool, M.4
Willart, M.A.5
-
111
-
-
0141998606
-
Molecular identification of a danger signal that alerts the immune system to dying cells
-
Shi Y, Evans JE, Rock KL. 2003. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425:516-21
-
(2003)
Nature
, vol.425
, pp. 516-521
-
-
Shi, Y.1
Evans, J.E.2
Rock, K.L.3
-
112
-
-
33746747096
-
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
-
Chen CJ, Shi Y, Hearn A, Fitzgerald K, Golenbock D, et al. 2006. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J. Clin. Invest. 116:2262-71
-
(2006)
J. Clin. Invest
, vol.116
, pp. 2262-2271
-
-
Chen, C.J.1
Shi, Y.2
Hearn, A.3
Fitzgerald, K.4
Golenbock, D.5
-
113
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA. 2008. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453:1122-26
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
114
-
-
33646022583
-
Cutting edge: Elimination of an endogenous adjuvant reduces the activation of CD8T lymphocytes to transplanted cells and in an autoimmune diabetes model
-
Shi Y, Galusha SA, Rock KL. 2006. Cutting edge: elimination of an endogenous adjuvant reduces the activation of CD8T lymphocytes to transplanted cells and in an autoimmune diabetes model. J. Immunol. 176:3905-8
-
(2006)
J. Immunol
, vol.176
, pp. 3905-3908
-
-
Shi, Y.1
Galusha, S.A.2
Rock, K.L.3
-
115
-
-
42949089929
-
-
Orengo J, Evans J, Bettiol E, Leliwa-Sytek A, Day K, et al. 2008. Plasmodium-induced inflammation by uric acid. PLoS Pathogens 4:e1000013
-
Orengo J, Evans J, Bettiol E, Leliwa-Sytek A, Day K, et al. 2008. Plasmodium-induced inflammation by uric acid. PLoS Pathogens 4:e1000013
-
-
-
-
116
-
-
42249088234
-
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
-
Kool M, Soullié T, Van Nimwegen M, Willart MA, Muskens F, et al. 2008. Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J. Exp. Med. 205:869-82
-
(2008)
J. Exp. Med
, vol.205
, pp. 869-882
-
-
Kool, M.1
Soullié, T.2
Van Nimwegen, M.3
Willart, M.A.4
Muskens, F.5
-
117
-
-
47849087075
-
Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3
-
Li H, Willingham SB, Ting JP, Re F. 2008. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J. Immunol. 181:17-21
-
(2008)
J. Immunol
, vol.181
, pp. 17-21
-
-
Li, H.1
Willingham, S.B.2
Ting, J.P.3
Re, F.4
-
118
-
-
50849112477
-
The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity
-
Franchi L, Núñez G. 2008. The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity. Eur. J. Immunol. 38:2085-89
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 2085-2089
-
-
Franchi, L.1
Núñez, G.2
-
119
-
-
67650754318
-
Alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
-
Kool M, Pétrilli V, De Smedt T, Rolaz A, Hammad H, et al. 2008. Alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J. Immunol. 205:869-82
-
(2008)
J. Immunol
, vol.205
, pp. 869-882
-
-
Kool, M.1
Pétrilli, V.2
De Smedt, T.3
Rolaz, A.4
Hammad, H.5
-
121
-
-
34250731657
-
Recent developments in crystal-induced inflammation pathogenesis and management
-
Lioté F, Ea HK. 2007. Recent developments in crystal-induced inflammation pathogenesis and management. Curr. Rheumatol. Rep. 9:243-50
-
(2007)
Curr. Rheumatol. Rep
, vol.9
, pp. 243-250
-
-
Lioté, F.1
Ea, H.K.2
-
123
-
-
34548667797
-
Management of treatment resistant inflammation of acute or chronic tophaceous gout with anakinra
-
McGonagle D, Tan A, Shankaranarayana S, Madden J, Emery P, McDermott M. 2007. Management of treatment resistant inflammation of acute or chronic tophaceous gout with anakinra. Ann. Rheum. Dis. 66:1683-84
-
(2007)
Ann. Rheum. Dis
, vol.66
, pp. 1683-1684
-
-
McGonagle, D.1
Tan, A.2
Shankaranarayana, S.3
Madden, J.4
Emery, P.5
McDermott, M.6
-
124
-
-
39749175570
-
Successful treatment of resistant pseudogout with anakinra
-
McGonagle D, Tan AL, Madden J, Emery P, McDermott MF. 2008. Successful treatment of resistant pseudogout with anakinra. Arthritis Rheum. 58:631-33
-
(2008)
Arthritis Rheum
, vol.58
, pp. 631-633
-
-
McGonagle, D.1
Tan, A.L.2
Madden, J.3
Emery, P.4
McDermott, M.F.5
-
125
-
-
35748974543
-
-
Otsuki T, Maeda M, Murakami S, Hayashi H, Miura Y, et al. 2007. Immunological effects of silica and asbestos. Cell Mol. Immunol. 4:261-68
-
Otsuki T, Maeda M, Murakami S, Hayashi H, Miura Y, et al. 2007. Immunological effects of silica and asbestos. Cell Mol. Immunol. 4:261-68
-
-
-
-
126
-
-
0030995938
-
Asbestosis and silicosis
-
Wagner GR. 1997. Asbestosis and silicosis. Lancet 349:1311-15
-
(1997)
Lancet
, vol.349
, pp. 1311-1315
-
-
Wagner, G.R.1
-
127
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C, Petrilli V, van Bruggen R, Steele C, Mossman BT, Tschopp J. 2008. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320:674-77
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
128
-
-
47849132947
-
The Nalp3 inflammasome is essential for the development of silicosis
-
Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, et al. 2008. The Nalp3 inflammasome is essential for the development of silicosis. Proc. Natl. Acad. Sci. USA 105:9035-40
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 9035-9040
-
-
Cassel, S.L.1
Eisenbarth, S.C.2
Iyer, S.S.3
Sadler, J.J.4
Colegio, O.R.5
-
129
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, et al. 2008. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 9:847-56
-
(2008)
Nat. Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
-
130
-
-
36048962961
-
How do adjuvants work? Important considerations for new generation adjuvants
-
McKee AS, Munks MW, Marrack P. 2007. How do adjuvants work? Important considerations for new generation adjuvants. Immunity 27:687-90
-
(2007)
Immunity
, vol.27
, pp. 687-690
-
-
McKee, A.S.1
Munks, M.W.2
Marrack, P.3
-
131
-
-
7044274793
-
Aluminium compounds for use in vaccines
-
Lindblad EB. 2004. Aluminium compounds for use in vaccines. Immunol. Cell Biol. 82:497-505
-
(2004)
Immunol. Cell Biol
, vol.82
, pp. 497-505
-
-
Lindblad, E.B.1
-
132
-
-
0021828474
-
Modulation of the human immune response by the nontoxic and nonpyrogenic adjuvant aluminium hydroxide: Effect on antigen uptake and antigen presentation
-
Mannhalter JW, Neychev HO, Zlabinger GJ, Ahmad R, Eibl MM. 1985. Modulation of the human immune response by the nontoxic and nonpyrogenic adjuvant aluminium hydroxide: effect on antigen uptake and antigen presentation. Clin. Exp. Immunol. 61:143-51
-
(1985)
Clin. Exp. Immunol
, vol.61
, pp. 143-151
-
-
Mannhalter, J.W.1
Neychev, H.O.2
Zlabinger, G.J.3
Ahmad, R.4
Eibl, M.M.5
-
133
-
-
0024328379
-
Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: The role of endogenous interleukin 1 in proliferative responses
-
Grun JL, Maurer PH. 1989. Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: the role of endogenous interleukin 1 in proliferative responses. Cell Immunol. 121:134-45
-
(1989)
Cell Immunol
, vol.121
, pp. 134-145
-
-
Grun, J.L.1
Maurer, P.H.2
-
134
-
-
34247106805
-
Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1β and IL-18 release
-
Li H, Nookala S, Re F. 2007. Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1β and IL-18 release. J. Immunol. 178:5271-76
-
(2007)
J. Immunol
, vol.178
, pp. 5271-5276
-
-
Li, H.1
Nookala, S.2
Re, F.3
-
135
-
-
34250835251
-
The inflammasome mediates UVB-induced activation and secretion of interleukin-1β by keratinocytes
-
Feldmeyer L, Keller M, Niklaus G, Hohl D, Werner S, Beer HD. 2007. The inflammasome mediates UVB-induced activation and secretion of interleukin-1β by keratinocytes. Curr. Biol. 17:1140-45
-
(2007)
Curr. Biol
, vol.17
, pp. 1140-1145
-
-
Feldmeyer, L.1
Keller, M.2
Niklaus, G.3
Hohl, D.4
Werner, S.5
Beer, H.D.6
-
137
-
-
0029916522
-
Mice deficient in IL-1β manifest impaired contact hypersensitivity to trinitrochlorobenzone
-
Shornick LP, De Togni P, Mariathasan S, Goellner J, Strauss-Schoenberger J, et al. 1996. Mice deficient in IL-1β manifest impaired contact hypersensitivity to trinitrochlorobenzone. J. Exp. Med. 183:1427-36
-
(1996)
J. Exp. Med
, vol.183
, pp. 1427-1436
-
-
Shornick, L.P.1
De Togni, P.2
Mariathasan, S.3
Goellner, J.4
Strauss-Schoenberger, J.5
-
138
-
-
0031573598
-
Induction of biologically active IL-1β-converting enzyme and mature IL-1β in human keratinocytes by inflammatory and immunologic stimuli
-
Zepter K, Häffner A, Soohoo LF, De Luca D, Tang HP, et al. 1997. Induction of biologically active IL-1β-converting enzyme and mature IL-1β in human keratinocytes by inflammatory and immunologic stimuli. J. Immunol. 159:6203-8
-
(1997)
J. Immunol
, vol.159
, pp. 6203-6208
-
-
Zepter, K.1
Häffner, A.2
Soohoo, L.F.3
De Luca, D.4
Tang, H.P.5
-
139
-
-
0035869399
-
Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice
-
Antonopoulos C, Cumberbatch M, Dearman RJ, Daniel RJ, Kimber I, Groves RW. 2001. Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice. J. Immunol. 166:3672-77
-
(2001)
J. Immunol
, vol.166
, pp. 3672-3677
-
-
Antonopoulos, C.1
Cumberbatch, M.2
Dearman, R.J.3
Daniel, R.J.4
Kimber, I.5
Groves, R.W.6
-
140
-
-
0036533572
-
Contribution of Langerhans cell-derived IL-18 to contact hypersensitivity
-
Wang B, Feliciani C, Howell BG, Freed I, Cai Q, et al. 2002. Contribution of Langerhans cell-derived IL-18 to contact hypersensitivity. J. Immunol. 168:3303-8
-
(2002)
J. Immunol
, vol.168
, pp. 3303-3308
-
-
Wang, B.1
Feliciani, C.2
Howell, B.G.3
Freed, I.4
Cai, Q.5
-
141
-
-
34250792190
-
Activation of the IL-1β-processing inflammasome is involved in contact hypersensitivity
-
Watanabe H, Gaide O, Pétrilli V, Martinon F, Contassot E, et al. 2007. Activation of the IL-1β-processing inflammasome is involved in contact hypersensitivity. J. Invest. Dermatol. 127:1956-63
-
(2007)
J. Invest. Dermatol
, vol.127
, pp. 1956-1963
-
-
Watanabe, H.1
Gaide, O.2
Pétrilli, V.3
Martinon, F.4
Contassot, E.5
-
142
-
-
34447535325
-
Inflammasome activation in delayed-type hypersensitivity reactions
-
Yazdi AS, Ghoreschi K, Röcken M. 2007. Inflammasome activation in delayed-type hypersensitivity reactions. J. Investig. Dermatol. 127:1853-55
-
(2007)
J. Investig. Dermatol
, vol.127
, pp. 1853-1855
-
-
Yazdi, A.S.1
Ghoreschi, K.2
Röcken, M.3
-
143
-
-
44449165058
-
Danger signaling through the inflammasome acts as a master switch between tolerance and sensitization
-
Watanabe H, Gehrke S, Contassot E, Roques S, Tschopp J, et al. 2008. Danger signaling through the inflammasome acts as a master switch between tolerance and sensitization. J. Immunol. 180:5826-32
-
(2008)
J. Immunol
, vol.180
, pp. 5826-5832
-
-
Watanabe, H.1
Gehrke, S.2
Contassot, E.3
Roques, S.4
Tschopp, J.5
-
144
-
-
0026545368
-
The macrophage capacity for phagocytosis
-
Cannon GJ, Swanson JA. 1992. The macrophage capacity for phagocytosis. J. Cell Sci. 101(Pt. 4):907-13
-
(1992)
J. Cell Sci
, vol.101
, Issue.PART. 4
, pp. 907-913
-
-
Cannon, G.J.1
Swanson, J.A.2
-
145
-
-
34547772739
-
Microtubules regulate PI-3K activity and recruitment to the phagocytic cup during Fcγ receptor-mediated phagocytosis in nonelicited macrophages
-
Khandani A, Eng E, Jongstra-Bilen J, Schreiber AD, Douda D, et al. 2007. Microtubules regulate PI-3K activity and recruitment to the phagocytic cup during Fcγ receptor-mediated phagocytosis in nonelicited macrophages. J. Leukoc. Biol. 82:417-28
-
(2007)
J. Leukoc. Biol
, vol.82
, pp. 417-428
-
-
Khandani, A.1
Eng, E.2
Jongstra-Bilen, J.3
Schreiber, A.D.4
Douda, D.5
-
146
-
-
33745226185
-
A concise history of gout and hyperuricemia and their treatment
-
Nuki G, Simkin PA. 2006. A concise history of gout and hyperuricemia and their treatment. Arthritis Res. Ther. 8(Suppl. 1):S1
-
(2006)
Arthritis Res. Ther
, vol.8
, Issue.SUPPL. 1
-
-
Nuki, G.1
Simkin, P.A.2
-
147
-
-
0038359740
-
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis
-
Fubini B, Hubbard A. 2003. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic. Biol. Med. 34:1507-16
-
(2003)
Free Radic. Biol. Med
, vol.34
, pp. 1507-1516
-
-
Fubini, B.1
Hubbard, A.2
-
148
-
-
0029319039
-
Iron and reactive oxygen species in the asbestos-induced tumor necrosis factor-α response from alveolar macrophages
-
Simeonova PP, Luster MI. 1995. Iron and reactive oxygen species in the asbestos-induced tumor necrosis factor-α response from alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 12:676-83
-
(1995)
Am. J. Respir. Cell Mol. Biol
, vol.12
, pp. 676-683
-
-
Simeonova, P.P.1
Luster, M.I.2
-
149
-
-
34047261260
-
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
-
Cruz CM, Rinna A, Forman HJ, Ventura AL, Persechini PM, Ojcius DM. 2007. ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J. Biol. Chem. 282:2871-79
-
(2007)
J. Biol. Chem
, vol.282
, pp. 2871-2879
-
-
Cruz, C.M.1
Rinna, A.2
Forman, H.J.3
Ventura, A.L.4
Persechini, P.M.5
Ojcius, D.M.6
-
150
-
-
51849095822
-
UV irradiation increases ROS production via PKCδ signaling in primary murine fibroblasts
-
Bossi O, Gartsbein M, Leitges M, Kuroki T, Grossman S, Tennenbaum T. 2008. UV irradiation increases ROS production via PKCδ signaling in primary murine fibroblasts. J. Cell Biochem. 105:194-207.
-
(2008)
J. Cell Biochem
, vol.105
, pp. 194-207
-
-
Bossi, O.1
Gartsbein, M.2
Leitges, M.3
Kuroki, T.4
Grossman, S.5
Tennenbaum, T.6
-
152
-
-
0033180574
-
Role of active oxygen species and NO in plant defence responses
-
Bolwell GP. 1999. Role of active oxygen species and NO in plant defence responses. Curr. Opin. Plant Biol. 2:287-94
-
(1999)
Curr. Opin. Plant Biol
, vol.2
, pp. 287-294
-
-
Bolwell, G.P.1
-
153
-
-
33751224777
-
SK channels mediate NADPH oxidase-independent reactive oxygen species production and apoptosis in granulocytes
-
Fay AJ, Qian X, Jan YN, Jan LY. 2006. SK channels mediate NADPH oxidase-independent reactive oxygen species production and apoptosis in granulocytes. Proc. Natl. Acad. Sci. USA 103:17548-53
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 17548-17553
-
-
Fay, A.J.1
Qian, X.2
Jan, Y.N.3
Jan, L.Y.4
-
154
-
-
44649132540
-
Host innate immune receptors and beyond: Making sense of microbial infections
-
Ishii KJ, Koyama S, Nakagawa A, Coban C, Akira S. 2008. Host innate immune receptors and beyond: making sense of microbial infections. Cell Host Microbe 3:352-63
-
(2008)
Cell Host Microbe
, vol.3
, pp. 352-363
-
-
Ishii, K.J.1
Koyama, S.2
Nakagawa, A.3
Coban, C.4
Akira, S.5
-
155
-
-
34548699677
-
The role of the inflammasome in cellular responses to toxins and bacterial effectors
-
Freche B, Reig N, Van Der Goot FG. 2007. The role of the inflammasome in cellular responses to toxins and bacterial effectors. Semin. Immunopathol. 29:249-60
-
(2007)
Semin. Immunopathol
, vol.29
, pp. 249-260
-
-
Freche, B.1
Reig, N.2
Van Der Goot, F.G.3
-
157
-
-
36248970136
-
Bacterial cell walls, innate immunity and immunoadjuvants
-
Strominger JL. 2007. Bacterial cell walls, innate immunity and immunoadjuvants. Nat. Immunol. 8:1269-71
-
(2007)
Nat. Immunol
, vol.8
, pp. 1269-1271
-
-
Strominger, J.L.1
-
158
-
-
0018866230
-
Components of mycobacteria and muramyl dipeptide with adjuvant activity induce lymphocyte activating factor
-
Oppenheim JJ, Togawa A, Chedid L, Mizel S. 1980. Components of mycobacteria and muramyl dipeptide with adjuvant activity induce lymphocyte activating factor. Cell Immunol. 50:71-81
-
(1980)
Cell Immunol
, vol.50
, pp. 71-81
-
-
Oppenheim, J.J.1
Togawa, A.2
Chedid, L.3
Mizel, S.4
-
159
-
-
7944232105
-
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
-
Martinon F, Agostini L, Meylan E, Tschopp J. 2004. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr. Biol. 14:1929-34
-
(2004)
Curr. Biol
, vol.14
, pp. 1929-1934
-
-
Martinon, F.1
Agostini, L.2
Meylan, E.3
Tschopp, J.4
-
160
-
-
44849136632
-
Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via cryopyrin/NLRP3 independently of Nod2
-
Marina-Garcia N, Franchi L, Kim Y, Miller D, Mcdonald C, et al. 2008. Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via cryopyrin/NLRP3 independently of Nod2. J. Immunol. 180:4050-57
-
(2008)
J. Immunol
, vol.180
, pp. 4050-4057
-
-
Marina-Garcia, N.1
Franchi, L.2
Kim, Y.3
Miller, D.4
Mcdonald, C.5
-
161
-
-
0025157945
-
Lack of response of murine peritoneal macrophages to in vitro activation by muramyl dipeptide (MDP). I. Macrophage activation by MDP is species dependent
-
Nagao S, Akagawa KS, Yamada K, Yagawa K, Tokunaga T, Kotani S. 1990. Lack of response of murine peritoneal macrophages to in vitro activation by muramyl dipeptide (MDP). I. Macrophage activation by MDP is species dependent. Microbiol. Immunol. 34:323-35
-
(1990)
Microbiol. Immunol
, vol.34
, pp. 323-335
-
-
Nagao, S.1
Akagawa, K.S.2
Yamada, K.3
Yagawa, K.4
Tokunaga, T.5
Kotani, S.6
-
162
-
-
0020062603
-
Genetic influences on the adjuvanticity of muramyl dipeptide in vivo
-
Staruch MJ, Wood DD. 1982. Genetic influences on the adjuvanticity of muramyl dipeptide in vivo. J. Immunol. 128:155-60
-
(1982)
J. Immunol
, vol.128
, pp. 155-160
-
-
Staruch, M.J.1
Wood, D.D.2
-
163
-
-
38349081519
-
Engagement of NOD2 has a dual effect on proIL-1β mRNA transcription and secretion of bioactive IL-1β
-
Ferwerda G, Kramer M, de Jong D, Piccini A, Joosten LA, et al. 2008. Engagement of NOD2 has a dual effect on proIL-1β mRNA transcription and secretion of bioactive IL-1β. Eur. J. Immunol. 38:184-91
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 184-191
-
-
Ferwerda, G.1
Kramer, M.2
de Jong, D.3
Piccini, A.4
Joosten, L.A.5
-
164
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-κB activity and IL-1β processing
-
Maeda S, Hsu LC, Liu H, Bankston LA, Iimura M, et al. 2005. Nod2 mutation in Crohn's disease potentiates NF-κB activity and IL-1β processing. Science 307:734-38
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.C.2
Liu, H.3
Bankston, L.A.4
Iimura, M.5
-
165
-
-
33947717153
-
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
-
Bruey JM, Bruey-Sedano N, Luciano F, Zhai D, Balpai R, et al. 2007. Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1. Cell 129:45-56
-
(2007)
Cell
, vol.129
, pp. 45-56
-
-
Bruey, J.M.1
Bruey-Sedano, N.2
Luciano, F.3
Zhai, D.4
Balpai, R.5
-
166
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, et al. 2007. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 448:501-5
-
(2007)
Nature
, vol.448
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
-
168
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
Muruve DA, Pétrilli V, Zaiss AK, White LR, Clark SA, et al. 2008. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452:103-7
-
(2008)
Nature
, vol.452
, pp. 103-107
-
-
Muruve, D.A.1
Pétrilli, V.2
Zaiss, A.K.3
White, L.R.4
Clark, S.A.5
-
169
-
-
33846014297
-
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, et al. 2006. Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J. Biol. Chem. 281:36560-68
-
(2006)
J. Biol. Chem
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
Park, J.H.4
Whitfield, J.5
-
170
-
-
39149142237
-
Bacterial pore-forming toxins: The (w)hole story?
-
Gonzalez MR, Bischofberger M, Pernot L, Van Der Goot FG, Frêche B. 2008. Bacterial pore-forming toxins: the (w)hole story? Cell Mol. Life Sci. 65:493-507
-
(2008)
Cell Mol. Life Sci
, vol.65
, pp. 493-507
-
-
Gonzalez, M.R.1
Bischofberger, M.2
Pernot, L.3
Van Der Goot, F.G.4
Frêche, B.5
-
171
-
-
33748598700
-
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
-
Gurcel L, Abrami L, Girardin S, Tschopp J, Van Der Goot FG. 2006. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell 126:1135-45
-
(2006)
Cell
, vol.126
, pp. 1135-1145
-
-
Gurcel, L.1
Abrami, L.2
Girardin, S.3
Tschopp, J.4
Van Der Goot, F.G.5
-
172
-
-
33646017449
-
Distinct roles of TLR2 and the adaptor ASC in IL-1β/IL-18 secretion in response to Listeria monocytogenes
-
Ozören N, Masumoto J, Franchi L, Kanneganti TD, Body-Malapel M, et al. 2006. Distinct roles of TLR2 and the adaptor ASC in IL-1β/IL-18 secretion in response to Listeria monocytogenes. J. Immunol. 176:4337-42
-
(2006)
J. Immunol
, vol.176
, pp. 4337-4342
-
-
Ozören, N.1
Masumoto, J.2
Franchi, L.3
Kanneganti, T.D.4
Body-Malapel, M.5
-
173
-
-
50949083791
-
Dependency of caspase-1 activation induced in macrophages by Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm
-
Hara H, Tsuchiya K, Nomura T, Kawamura I, Shoma S, Mitsuyama M. 2008. Dependency of caspase-1 activation induced in macrophages by Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm. J. Immunol. 180:7859-68
-
(2008)
J. Immunol
, vol.180
, pp. 7859-7868
-
-
Hara, H.1
Tsuchiya, K.2
Nomura, T.3
Kawamura, I.4
Shoma, S.5
Mitsuyama, M.6
-
174
-
-
47249095738
-
Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection
-
Warren SE, Mao DP, Rodriguez AE, Miao EA, Aderem A. 2008. Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection. J. Immunol. 180:7558-64
-
(2008)
J. Immunol
, vol.180
, pp. 7558-7564
-
-
Warren, S.E.1
Mao, D.P.2
Rodriguez, A.E.3
Miao, E.A.4
Aderem, A.5
-
175
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
Boyden E, Dietrich W. 2006. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat. Genet. 38:240-44
-
(2006)
Nat. Genet
, vol.38
, pp. 240-244
-
-
Boyden, E.1
Dietrich, W.2
-
176
-
-
41949127121
-
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
-
Fink SL, Bergsbaken T, Cookson BT. 2008. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc. Natl. Acad. Sci. USA 105:4312-17
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4312-4317
-
-
Fink, S.L.1
Bergsbaken, T.2
Cookson, B.T.3
-
177
-
-
38049119726
-
Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome
-
Wickliffe KE, Leppla SH, Moayeri M. 2008. Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome. Cell Microbiol. 10:332-43
-
(2008)
Cell Microbiol
, vol.10
, pp. 332-343
-
-
Wickliffe, K.E.1
Leppla, S.H.2
Moayeri, M.3
-
178
-
-
36349019887
-
Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing
-
Squires RC, Muehlbauer SM, Brojatsch J. 2007. Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing. J. Biol. Chem. 282:34260-67
-
(2007)
J. Biol. Chem
, vol.282
, pp. 34260-34267
-
-
Squires, R.C.1
Muehlbauer, S.M.2
Brojatsch, J.3
-
179
-
-
33745012076
-
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis
-
Lara-Tejero M, Sutterwala FS, Ogura Y, Grant EP, Bertin J, et al. 2006. Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J. Exp. Med. 203:1407-12
-
(2006)
J. Exp. Med
, vol.203
, pp. 1407-1412
-
-
Lara-Tejero, M.1
Sutterwala, F.S.2
Ogura, Y.3
Grant, E.P.4
Bertin, J.5
-
180
-
-
33645843633
-
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
-
Molofsky AB, Byrne BG, Whitfield NN, Madigan CA, Fuse ET, et al. 2006. Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection. J. Exp. Med. 203:1093-104
-
(2006)
J. Exp. Med
, vol.203
, pp. 1093-1104
-
-
Molofsky, A.B.1
Byrne, B.G.2
Whitfield, N.N.3
Madigan, C.A.4
Fuse, E.T.5
-
181
-
-
33645791082
-
Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity
-
Ren T, Zamboni DS, Roy CR, Dietrich W, Vance RE. 2006. Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. PLoS Pathog. 2:e18
-
(2006)
PLoS Pathog
, vol.2
-
-
Ren, T.1
Zamboni, D.S.2
Roy, C.R.3
Dietrich, W.4
Vance, R.E.5
-
182
-
-
33645770203
-
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
-
Zamboni DS, Kobayashi KS, Kohlsdorf T, Ogura Y, Long EM, et al. 2006. The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat. Immunol. 7:318-25
-
(2006)
Nat. Immunol
, vol.7
, pp. 318-325
-
-
Zamboni, D.S.1
Kobayashi, K.S.2
Kohlsdorf, T.3
Ogura, Y.4
Long, E.M.5
-
183
-
-
34250195275
-
The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation
-
Lamkanfi M, Amer A, Kanneganti TD, Muñoz-Planillo R, Chen G, et al. 2007. The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation. J. Immunol. 178:8022-27
-
(2007)
J. Immunol
, vol.178
, pp. 8022-8027
-
-
Lamkanfi, M.1
Amer, A.2
Kanneganti, T.D.3
Muñoz-Planillo, R.4
Chen, G.5
-
184
-
-
36248968798
-
ASC/PYCARD and caspase-1 regulate the IL-18/IFN-γ axis during Anaplasma phagocytophilum infection
-
Pedra JH, Sutterwala FS, Sukumaran B, Ogura Y, Qian F, et al. 2007. ASC/PYCARD and caspase-1 regulate the IL-18/IFN-γ axis during Anaplasma phagocytophilum infection. J. Immunol. 179:4783-91
-
(2007)
J. Immunol
, vol.179
, pp. 4783-4791
-
-
Pedra, J.H.1
Sutterwala, F.S.2
Sukumaran, B.3
Ogura, Y.4
Qian, F.5
-
185
-
-
40649090426
-
Pseudomonas aeruginosa activates caspase 1 through Ipaf
-
Miao EA, Ernst RK, Dors M, Mao DP, Aderem A. 2008. Pseudomonas aeruginosa activates caspase 1 through Ipaf. Proc. Natl. Acad. Sci. USA 105:2562-67
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 2562-2567
-
-
Miao, E.A.1
Ernst, R.K.2
Dors, M.3
Mao, D.P.4
Aderem, A.5
-
186
-
-
37549041954
-
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome
-
Sutterwala FS, Mijares LA, Li L, Ogura Y, Kazmierczak BI, Flavell RA. 2007. Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J. Exp. Med. 204:3235-45
-
(2007)
J. Exp. Med
, vol.204
, pp. 3235-3245
-
-
Sutterwala, F.S.1
Mijares, L.A.2
Li, L.3
Ogura, Y.4
Kazmierczak, B.I.5
Flavell, R.A.6
-
187
-
-
36248940773
-
Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation
-
Franchi L, Stoolman J, Kanneganti TD, Verma A, Ramphal R, Núñez G. 2007. Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation. Eur. J. Immunol. 37:3030-39
-
(2007)
Eur. J. Immunol
, vol.37
, pp. 3030-3039
-
-
Franchi, L.1
Stoolman, J.2
Kanneganti, T.D.3
Verma, A.4
Ramphal, R.5
Núñez, G.6
-
188
-
-
34548434775
-
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
-
Suzuki T, Franchi L, Toma C, Ashida H, Ogawa M, et al. 2007. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog. 3:e111
-
(2007)
PLoS Pathog
, vol.3
-
-
Suzuki, T.1
Franchi, L.2
Toma, C.3
Ashida, H.4
Ogawa, M.5
-
189
-
-
34249044447
-
Type I interferon signaling is required for activation of the inflammasome during Francisella infection
-
Henry T, Brotcke A, Weiss DS, Thompson LJ, Monack DM. 2007. Type I interferon signaling is required for activation of the inflammasome during
-
(2007)
J. Exp. Med
, vol.204
, pp. 987-994
-
-
Henry, T.1
Brotcke, A.2
Weiss, D.S.3
Thompson, L.J.4
Monack, D.M.5
-
190
-
-
34548225362
-
NF-κB is a negative regulator of IL-1β secretion as revealed by genetic and pharmacological inhibition of IKKβ
-
Greten FR, Arkan MC, Bollrath J, Hsu LC, Goode J, et al. 2007. NF-κB is a negative regulator of IL-1β secretion as revealed by genetic and pharmacological inhibition of IKKβ. Cell 130:918-31
-
(2007)
Cell
, vol.130
, pp. 918-931
-
-
Greten, F.R.1
Arkan, M.C.2
Bollrath, J.3
Hsu, L.C.4
Goode, J.5
-
191
-
-
40049108218
-
COPs and POPs: Modulators of inflammasome activity
-
Stehlik C, Dorfleutner A. 2007. COPs and POPs: Modulators of inflammasome activity. J. Immunol. 179:7993-98
-
(2007)
J. Immunol
, vol.179
, pp. 7993-7998
-
-
Stehlik, C.1
Dorfleutner, A.2
-
192
-
-
35548929476
-
A Shope Fibroma virus PYRIN-only protein modulates the host immune response
-
Dorfleutner A, Talbott SJ, Bryan NB, Funya KN, Rellick SL, et al. 2007. A Shope Fibroma virus PYRIN-only protein modulates the host immune response. Virus Genes 35:685-94
-
(2007)
Virus Genes
, vol.35
, pp. 685-694
-
-
Dorfleutner, A.1
Talbott, S.J.2
Bryan, N.B.3
Funya, K.N.4
Rellick, S.L.5
-
193
-
-
28844437999
-
Poxviruses aren't stuPYD
-
Benedict CA, Ware CF. 2005. Poxviruses aren't stuPYD. Immunity 23:553-55
-
(2005)
Immunity
, vol.23
, pp. 553-555
-
-
Benedict, C.A.1
Ware, C.F.2
-
194
-
-
28844466449
-
A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection
-
Johnston JB, Barrett JW, Nazarian SH, Goodwin M, Ricciuto D, et al. 2005. A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection. Immunity 23:587-98
-
(2005)
Immunity
, vol.23
, pp. 587-598
-
-
Johnston, J.B.1
Barrett, J.W.2
Nazarian, S.H.3
Goodwin, M.4
Ricciuto, D.5
-
195
-
-
33947219338
-
Pyrin-only protein 2 modulates NF-κB and disrupts ASC:CLR interactions
-
Bedoya F, Sandler LL, Harton JA. 2007. Pyrin-only protein 2 modulates NF-κB and disrupts ASC:CLR interactions. J. Immunol. 178:3837-45
-
(2007)
J. Immunol
, vol.178
, pp. 3837-3845
-
-
Bedoya, F.1
Sandler, L.L.2
Harton, J.A.3
-
196
-
-
16944365196
-
A candidate gene for familial Mediterranean fever
-
The French FMF Consortium
-
The French FMF Consortium. 1997. A candidate gene for familial Mediterranean fever. Nat. Genet. 17:25-31
-
(1997)
Nat. Genet
, vol.17
, pp. 25-31
-
-
-
197
-
-
0037349294
-
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
-
Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, et al. 2003. Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol. Cell 11:591-604
-
(2003)
Mol. Cell
, vol.11
, pp. 591-604
-
-
Chae, J.J.1
Komarow, H.D.2
Cheng, J.3
Wood, G.4
Raben, N.5
-
198
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Fernandes-Alnemri T, Wu J, Yu JW, Datta P, Miller B, et al. 2007. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 14:1590-604
-
(2007)
Cell Death Differ
, vol.14
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
Datta, P.4
Miller, B.5
-
199
-
-
5444222071
-
A common pathway in periodic fever syndromes
-
McDermott MF. 2004. A common pathway in periodic fever syndromes. Trends Immunol. 25:457-60
-
(2004)
Trends Immunol
, vol.25
, pp. 457-460
-
-
McDermott, M.F.1
-
200
-
-
0344823965
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
Shoham NG, Centola M, Mansfield E, Hull KM, Wood G, et al. 2003. Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. Proc. Natl. Acad. Sci. USA 100:13501-6
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
Centola, M.2
Mansfield, E.3
Hull, K.M.4
Wood, G.5
-
201
-
-
33645734214
-
Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease
-
Grosse J, Chitu V, Marquardt A, Hanke P, Schmittwolf C, et al. 2006. Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease. Blood 107:3350-58
-
(2006)
Blood
, vol.107
, pp. 3350-3358
-
-
Grosse, J.1
Chitu, V.2
Marquardt, A.3
Hanke, P.4
Schmittwolf, C.5
-
202
-
-
29344448820
-
A missense mutation in pstpip2 is associated with the murine autoinflammatory disorder chronic multifocal osteomyelitis
-
Ferguson PJ, Bing X, Vasef MA, Ochoa LA, Mahgoub A, et al. 2006. A missense mutation in pstpip2 is associated with the murine autoinflammatory disorder chronic multifocal osteomyelitis. Bone 38:41-47
-
(2006)
Bone
, vol.38
, pp. 41-47
-
-
Ferguson, P.J.1
Bing, X.2
Vasef, M.A.3
Ochoa, L.A.4
Mahgoub, A.5
-
203
-
-
46649083006
-
Different evolutionary strategies for the origin of caspase-1 inhibitors
-
da Cunha JP, Galante PA, de Souza SJ. 2008. Different evolutionary strategies for the origin of caspase-1 inhibitors. J. Mol. Evol. 66:591-97
-
(2008)
J. Mol. Evol
, vol.66
, pp. 591-597
-
-
da Cunha, J.P.1
Galante, P.A.2
de Souza, S.J.3
-
204
-
-
37749030247
-
Aphylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins
-
Kersse K, Vanden Berghe T, Lamkanfi M, Vandenabeele P. 2007. Aphylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins. Biochem. Soc. Trans. 35:1508-11
-
(2007)
Biochem. Soc. Trans
, vol.35
, pp. 1508-1511
-
-
Kersse, K.1
Vanden Berghe, T.2
Lamkanfi, M.3
Vandenabeele, P.4
-
205
-
-
2342457148
-
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
-
Saleh M, Vaillancourt JP, Graham RK, Huyck M, Srinivasula SM, et al. 2004. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature 429:75-79
-
(2004)
Nature
, vol.429
, pp. 75-79
-
-
Saleh, M.1
Vaillancourt, J.P.2
Graham, R.K.3
Huyck, M.4
Srinivasula, S.M.5
-
206
-
-
33750582592
-
Population distribution of the functional caspase-12 allele
-
Kachapati K, O'Brien TR, Bergeron J, Zhang M, Dean M. 2006. Population distribution of the functional caspase-12 allele. Hum. Mutat. 27:975
-
(2006)
Hum. Mutat
, vol.27
, pp. 975
-
-
Kachapati, K.1
O'Brien, T.R.2
Bergeron, J.3
Zhang, M.4
Dean, M.5
-
208
-
-
33645462359
-
Spread of an inactive form of caspase-12 in humans is due to recent positive selection
-
Xue Y, Daly A, Yngvadottir B, Liu M, Coop G, et al. 2006. Spread of an inactive form of caspase-12 in humans is due to recent positive selection. Am. J. Hum. Genet. 78:659-70
-
(2006)
Am. J. Hum. Genet
, vol.78
, pp. 659-670
-
-
Xue, Y.1
Daly, A.2
Yngvadottir, B.3
Liu, M.4
Coop, G.5
-
209
-
-
33646175602
-
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
-
Saleh M, Mathison JC, Wolinski MK, Bensinger SJ, Fitzgerald P, et al. 2006. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature 440:1064-68
-
(2006)
Nature
, vol.440
, pp. 1064-1068
-
-
Saleh, M.1
Mathison, J.C.2
Wolinski, M.K.3
Bensinger, S.J.4
Fitzgerald, P.5
-
210
-
-
41949115934
-
Confinement of caspase-12 proteolytic activity to autoprocessing
-
Roy S, Sharom JR, Houde C, Loisel TP, Vaillancourt JP, et al. 2008. Confinement of caspase-12 proteolytic activity to autoprocessing. Proc. Natl. Acad. Sci. USA 105:4133-38
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4133-4138
-
-
Roy, S.1
Sharom, J.R.2
Houde, C.3
Loisel, T.P.4
Vaillancourt, J.P.5
-
211
-
-
33847672241
-
NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1
-
Miggin SM, Pålsson-McDermott E, Dunne A, Jefferies C, Pinteaux E, et al. 2007. NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1. Proc. Natl. Acad. Sci. USA 104:3372-77
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 3372-3377
-
-
Miggin, S.M.1
Pålsson-McDermott, E.2
Dunne, A.3
Jefferies, C.4
Pinteaux, E.5
-
212
-
-
39749084641
-
Active caspase-1 is a regulator of unconventional protein secretion
-
Keller M, Rüegg A, Werner S, Beer HD. 2008. Active caspase-1 is a regulator of unconventional protein secretion. Cell 132:818-31
-
(2008)
Cell
, vol.132
, pp. 818-831
-
-
Keller, M.1
Rüegg, A.2
Werner, S.3
Beer, H.D.4
-
213
-
-
52649104806
-
The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-κB through its N-terminal fragment
-
Chae JJ, Wood G, Richard K, Jaffe H, Colburn NT, et al. 2008. The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-κB through its N-terminal fragment. Blood 112:1794-803
-
(2008)
Blood
, vol.112
, pp. 1794-1803
-
-
Chae, J.J.1
Wood, G.2
Richard, K.3
Jaffe, H.4
Colburn, N.T.5
-
214
-
-
8344261590
-
Infection, fever, and exogenous and endogenous pyrogens: Some concepts have changed
-
Dinarello CA. 2004. Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed. J. Endotoxin Res. 10:201-22
-
(2004)
J. Endotoxin Res
, vol.10
, pp. 201-222
-
-
Dinarello, C.A.1
-
215
-
-
0035932121
-
Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity
-
Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, et al. 2001. Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410:471-75
-
(2001)
Nature
, vol.410
, pp. 471-475
-
-
Samad, T.A.1
Moore, K.A.2
Sapirstein, A.3
Billet, S.4
Allchorne, A.5
-
216
-
-
34548675581
-
The NLR network and the immunological disease continuum of adaptive and innate immune-mediated inflammation against self
-
McGonagle D, Savic S, McDermott MF. 2007. The NLR network and the immunological disease continuum of adaptive and innate immune-mediated inflammation against self. Semin. Immunopathol. 29:303-13
-
(2007)
Semin. Immunopathol
, vol.29
, pp. 303-313
-
-
McGonagle, D.1
Savic, S.2
McDermott, M.F.3
-
217
-
-
33748367018
-
A proposed classification of the immunological diseases
-
McGonagle D, McDermott MF. 2006. A proposed classification of the immunological diseases. PLoS Med. 3:e297
-
(2006)
PLoS Med
, vol.3
-
-
McGonagle, D.1
McDermott, M.F.2
-
218
-
-
34247252063
-
The clinical continuum of cryopyrinopathies: Novel CIAS1 mutations in North American patients and a new cryopyrin model
-
Aksentijevich I, Putnam CD, Remmers EF, Mueller JL, Le J, et al. 2007. The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model. Arthritis Rheum. 56:1273-85
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1273-1285
-
-
Aksentijevich, I.1
Putnam, C.D.2
Remmers, E.F.3
Mueller4
JL, L.J.5
-
221
-
-
2542452727
-
Cryopyrin-induced interleukin 1β secretion in monocytic cells: Enhanced activity of disease-associated mutants and requirement for ASC
-
Dowds TA, Masumoto J, Zhu L, Inohara N, Núñez G. 2004. Cryopyrin-induced interleukin 1β secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC. J. Biol. Chem. 279:21924-28
-
(2004)
J. Biol. Chem
, vol.279
, pp. 21924-21928
-
-
Dowds, T.A.1
Masumoto, J.2
Zhu, L.3
Inohara, N.4
Núñez, G.5
-
222
-
-
33746876396
-
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition
-
Goldbach-Mansky R, Dailey NJ, Canna SW, Gelabert A, Jones J, et al. 2006. Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition. N. Engl. J. Med. 355:581-92
-
(2006)
N. Engl. J. Med
, vol.355
, pp. 581-592
-
-
Goldbach-Mansky, R.1
Dailey, N.J.2
Canna, S.W.3
Gelabert, A.4
Jones, J.5
-
223
-
-
1042290321
-
Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra
-
Hawkins PN, Lachmann HJ, Aganna E, McDermott MF. 2004. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum. 50:607-12
-
(2004)
Arthritis Rheum
, vol.50
, pp. 607-612
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Aganna, E.3
McDermott, M.F.4
-
224
-
-
0037792866
-
Interleukin-1-receptor antagonist in the Muckle-Wells syndrome
-
Hawkins PN, Lachmann HJ, McDermott MF. 2003. Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. N. Engl. J. Med. 348:2583-84
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 2583-2584
-
-
Hawkins, P.N.1
Lachmann, H.J.2
McDermott, M.F.3
-
225
-
-
8444225132
-
Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist
-
Hoffman HM, Rosengren S, Boyle DL, Cho JY, Nayar J, et al. 2004. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 364:1779-85
-
(2004)
Lancet
, vol.364
, pp. 1779-1785
-
-
Hoffman, H.M.1
Rosengren, S.2
Boyle, D.L.3
Cho, J.Y.4
Nayar, J.5
-
226
-
-
34548522759
-
From inflammasomes to fevers, crystals and hypertension: How basic research explains inflammatory diseases
-
McDermott MF, Tschopp J. 2007. From inflammasomes to fevers, crystals and hypertension: how basic research explains inflammatory diseases. Trends Mol. Med. 13:381-88
-
(2007)
Trends Mol. Med
, vol.13
, pp. 381-388
-
-
McDermott, M.F.1
Tschopp, J.2
-
227
-
-
33845905223
-
Adjuvant-enhanced antibody responses in the absence of Toll-like receptor signaling
-
Gavin AL, Hoebe K, Duong B, Ota T, Martin C, et al. 2006. Adjuvant-enhanced antibody responses in the absence of Toll-like receptor signaling. Science 314:1936-38
-
(2006)
Science
, vol.314
, pp. 1936-1938
-
-
Gavin, A.L.1
Hoebe, K.2
Duong, B.3
Ota, T.4
Martin, C.5
-
228
-
-
38449101266
-
IL-1α and IL-1β are endogenous mediators linking cell injury to the adaptive alloimmune response
-
Rao DA, Tracey KJ, Pober JS. 2007. IL-1α and IL-1β are endogenous mediators linking cell injury to the adaptive alloimmune response. J. Immunol. 179:6536-46
-
(2007)
J. Immunol
, vol.179
, pp. 6536-6546
-
-
Rao, D.A.1
Tracey, K.J.2
Pober, J.S.3
-
229
-
-
34548125305
-
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
-
Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F. 2007. Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells. Nat. Immunol. 8:942-49
-
(2007)
Nat. Immunol
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
231
-
-
33846238175
-
Type 2 immune response associated with silicosis is not instrumental in the development of the disease
-
Misson P, Brombacher F, Delos M, Lison D, Huaux F. 2007. Type 2 immune response associated with silicosis is not instrumental in the development of the disease. Am. J. Physiol. Lung Cell Mol. Physiol. 292:L107-13
-
(2007)
Am. J. Physiol. Lung Cell Mol. Physiol
, vol.292
-
-
Misson, P.1
Brombacher, F.2
Delos, M.3
Lison, D.4
Huaux, F.5
-
232
-
-
10944261462
-
Interleukin 1 plays a major role in the development of Th2-mediated immunity
-
Helmby H, Grencis R. 2004. Interleukin 1 plays a major role in the development of Th2-mediated immunity. Eur. J. Immunol. 34:3674-81
-
(2004)
Eur. J. Immunol
, vol.34
, pp. 3674-3681
-
-
Helmby, H.1
Grencis, R.2
-
233
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, et al. 2005. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23:479-90
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
Song, Y.4
Murphy, E.5
-
234
-
-
0035071329
-
Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu
-
Nakanishi K, Yoshimoto T, Tsutsui H, Okamura H. 2001. Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Cytokine Growth Factor Rev. 12:53-72
-
(2001)
Cytokine Growth Factor Rev
, vol.12
, pp. 53-72
-
-
Nakanishi, K.1
Yoshimoto, T.2
Tsutsui, H.3
Okamura, H.4
-
235
-
-
33947497237
-
NALP1 in vitiligo-associated multiple autoimmune disease
-
Jin Y, Mailloux CM, Gowan K, Riccardi SL, LaBerge G, et al. 2007. NALP1 in vitiligo-associated multiple autoimmune disease. N. Engl. J. Med. 356:1216-25
-
(2007)
N. Engl. J. Med
, vol.356
, pp. 1216-1225
-
-
Jin, Y.1
Mailloux, C.M.2
Gowan, K.3
Riccardi, S.L.4
LaBerge, G.5
-
236
-
-
16244362671
-
Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
-
Fink SL, Cookson BT. 2005. Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infect. Immun. 73:1907-16
-
(2005)
Infect. Immun
, vol.73
, pp. 1907-1916
-
-
Fink, S.L.1
Cookson, B.T.2
-
237
-
-
0026635783
-
Shigella flexneri induces apoptosis in infected macrophages
-
Zychlinsky A, Prevost MC, Sansonetti PJ. 1992. Shigella flexneri induces apoptosis in infected macrophages. Nature 358:167-69
-
(1992)
Nature
, vol.358
, pp. 167-169
-
-
Zychlinsky, A.1
Prevost, M.C.2
Sansonetti, P.J.3
-
238
-
-
0029738195
-
A bacterial invasin induces macrophage apoptosis by binding directly to ICE
-
Chen Y, Smith MR, Thirumalai K, Zychlinsky A. 1996. A bacterial invasin induces macrophage apoptosis by binding directly to ICE. EMBO J. 15:3853-60
-
(1996)
EMBO J
, vol.15
, pp. 3853-3860
-
-
Chen, Y.1
Smith, M.R.2
Thirumalai, K.3
Zychlinsky, A.4
-
239
-
-
15644374367
-
Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB
-
Hilbi H, Moss JE, Hersh D, Chen Y, Arondel J, et al. 1998. Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB. J. Biol. Chem. 273:32895-900
-
(1998)
J. Biol. Chem
, vol.273
, pp. 32895-32900
-
-
Hilbi, H.1
Moss, J.E.2
Hersh, D.3
Chen, Y.4
Arondel, J.5
-
240
-
-
0033515032
-
The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
-
Hersh D, Monack DM, Smith MR, Ghori N, Falkow S, Zychlinsky A. 1999. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. Proc. Natl. Acad. Sci. USA 96:2396-401
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2396-2401
-
-
Hersh, D.1
Monack, D.M.2
Smith, M.R.3
Ghori, N.4
Falkow, S.5
Zychlinsky, A.6
-
241
-
-
26844452231
-
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
-
Mariathasan S, Weiss DS, Dixit VM, Monack DM. 2005. Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J. Exp. Med. 202:1043-49
-
(2005)
J. Exp. Med
, vol.202
, pp. 1043-1049
-
-
Mariathasan, S.1
Weiss, D.S.2
Dixit, V.M.3
Monack, D.M.4
-
242
-
-
37049037749
-
Intracytosolic Listeria monocytogenes induces cell death through caspase-1 activation in murine macrophages
-
Cervantes J, Nagata T, Uchijima M, Shibata K, Koide Y. 2008. Intracytosolic Listeria monocytogenes induces cell death through caspase-1 activation in murine macrophages. Cell Microbiol. 10:41-52
-
(2008)
Cell Microbiol
, vol.10
, pp. 41-52
-
-
Cervantes, J.1
Nagata, T.2
Uchijima, M.3
Shibata, K.4
Koide, Y.5
-
243
-
-
42149116277
-
Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin
-
Reig N, Jiang A, Couture R, Sutterwala FS, Ogura Y, et al. 2008. Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin. Cell Microbiol. 10:1190-207
-
(2008)
Cell Microbiol
, vol.10
, pp. 1190-1207
-
-
Reig, N.1
Jiang, A.2
Couture, R.3
Sutterwala, F.S.4
Ogura, Y.5
-
244
-
-
35348934890
-
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
-
Yu JW, Fernandes-Alnemri T, Datta P, Wu J, Juliana C, et al. 2007. Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants. Mol. Cell 28:214-27
-
(2007)
Mol. Cell
, vol.28
, pp. 214-227
-
-
Yu, J.W.1
Fernandes-Alnemri, T.2
Datta, P.3
Wu, J.4
Juliana, C.5
-
245
-
-
33845478357
-
The inflammatory caspases: Guardians against infections and sepsis
-
Scott AM, Saleh M. 2007. The inflammatory caspases: guardians against infections and sepsis. Cell Death Differ. 14:23-31
-
(2007)
Cell Death Differ
, vol.14
, pp. 23-31
-
-
Scott, A.M.1
Saleh, M.2
-
247
-
-
1442277112
-
TMS1/ASC: The cancer connection
-
McConnell B, Vertino P. 2004. TMS1/ASC: the cancer connection. Apoptosis 9:5-18
-
(2004)
Apoptosis
, vol.9
, pp. 5-18
-
-
McConnell, B.1
Vertino, P.2
-
248
-
-
42549161426
-
Acute neurodegeneration and the inflammasome: Central processor for danger signals and the inflammatory response?
-
Trendelenburg G. 2008. Acute neurodegeneration and the inflammasome: central processor for danger signals and the inflammatory response? J. Cereb. Blood Flow Metab. 28:867-81
-
(2008)
J. Cereb. Blood Flow Metab
, vol.28
, pp. 867-881
-
-
Trendelenburg, G.1
-
249
-
-
0028896092
-
The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
-
Roy N, Mahadevan MS, McLean M, Shutler G, Yaraghi Z, et al. 1995. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 80:167-78
-
(1995)
Cell
, vol.80
, pp. 167-178
-
-
Roy, N.1
Mahadevan, M.S.2
McLean, M.3
Shutler, G.4
Yaraghi, Z.5
-
250
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, et al. 2008. The NALP3 inflammasome is involved in the innate immune response to amyloid-β. Nat. Immunol. 9:857-65
-
(2008)
Nat. Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
-
251
-
-
1542361218
-
The interleukin-1 system and female reproduction
-
Gérard N, Caillaud M, Martoriati A, Goudet G, Lalmanach AC. 2004. The interleukin-1 system and female reproduction. J. Endocrinol. 180:203-12
-
(2004)
J. Endocrinol
, vol.180
, pp. 203-212
-
-
Gérard, N.1
Caillaud, M.2
Martoriati, A.3
Goudet, G.4
Lalmanach, A.C.5
-
252
-
-
27344460591
-
In vivo effect of interleukin-1β and interleukin-1RA on oocyte cytoplasmic maturation, ovulation, and early embryonic development in the mare
-
Caillaud M, Duchamp G, Gérard N. 2005. In vivo effect of interleukin-1β and interleukin-1RA on oocyte cytoplasmic maturation, ovulation, and early embryonic development in the mare. Reprod. Biol. Endocrinol. 3:26
-
(2005)
Reprod. Biol. Endocrinol
, vol.3
, pp. 26
-
-
Caillaud, M.1
Duchamp, G.2
Gérard, N.3
-
253
-
-
0028180757
-
Effect of interleukin-1 β on ovulation in the in vitro perfused rabbit ovary
-
Takehara Y, Dharmarajan AM, Kaufman G, Wallach EE. 1994. Effect of interleukin-1 β on ovulation in the in vitro perfused rabbit ovary. Endocrinology 134:1788-93
-
(1994)
Endocrinology
, vol.134
, pp. 1788-1793
-
-
Takehara, Y.1
Dharmarajan, A.M.2
Kaufman, G.3
Wallach, E.E.4
-
254
-
-
0033757582
-
Mater, a maternal effect gene required for early embryonic development in mice
-
Tong ZB, Gold L, Pfeifer KE, Dorward H, Lee E, et al. 2000. Mater, a maternal effect gene required for early embryonic development in mice. Nat. Genet. 26:267-68
-
(2000)
Nat. Genet
, vol.26
, pp. 267-268
-
-
Tong, Z.B.1
Gold, L.2
Pfeifer, K.E.3
Dorward, H.4
Lee, E.5
-
255
-
-
34447649380
-
Women heterozygous for NALP7/NLRP7 mutations are at risk for reproductive wastage: Report of two novel mutations
-
Qian J, Deveault C, Bagga R, Xie X, Slim R. 2007. Women heterozygous for NALP7/NLRP7 mutations are at risk for reproductive wastage: report of two novel mutations. Hum. Mutat. 28:741
-
(2007)
Hum. Mutat
, vol.28
, pp. 741
-
-
Qian, J.1
Deveault, C.2
Bagga, R.3
Xie, X.4
Slim, R.5
-
256
-
-
33845543892
-
The genetics of hydatidiform moles: New lights on an ancient disease
-
Slim R, Mehio A. 2007. The genetics of hydatidiform moles: new lights on an ancient disease. Clin. Genet. 71:25-34
-
(2007)
Clin. Genet
, vol.71
, pp. 25-34
-
-
Slim, R.1
Mehio, A.2
-
257
-
-
33644615366
-
Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans
-
Murdoch S, Djuric U, Mazhar B, Seoud M, Khan R, et al. 2006. Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans. Nat. Genet. 38:300-2
-
(2006)
Nat. Genet
, vol.38
, pp. 300-302
-
-
Murdoch, S.1
Djuric, U.2
Mazhar, B.3
Seoud, M.4
Khan, R.5
-
258
-
-
37549002511
-
The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
-
Shao W, Yeretssian G, Doiron K, Hussain SN, Saleh M. 2007. The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. J. Biol. Chem. 282:36321-29
-
(2007)
J. Biol. Chem
, vol.282
, pp. 36321-36329
-
-
Shao, W.1
Yeretssian, G.2
Doiron, K.3
Hussain, S.N.4
Saleh, M.5
-
259
-
-
42449153825
-
Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity
-
Li J, Yin HL, Yuan J. 2008. Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity. J. Cell Biol. 181:321-33
-
(2008)
J. Cell Biol
, vol.181
, pp. 321-333
-
-
Li, J.1
Yin, H.L.2
Yuan, J.3
-
260
-
-
0034194055
-
The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1β-converting enzyme (caspase-1) activity in human vascular smooth muscle cells
-
Young JL, Sukhova GK, Foster D, Kisiel W, Libby P, Schönbeck U. 2000. The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1β-converting enzyme (caspase-1) activity in human vascular smooth muscle cells. J. Exp. Med. 191:1535-44
-
(2000)
J. Exp. Med
, vol.191
, pp. 1535-1544
-
-
Young, J.L.1
Sukhova, G.K.2
Foster, D.3
Kisiel, W.4
Libby, P.5
Schönbeck, U.6
-
261
-
-
0026728952
-
Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1 β converting enzyme
-
Ray CA, Black RA, Kronheim SR, Greenstreet TA, Sleath PR, et al. 1992. Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 β converting enzyme. Cell 69:597-604
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(1992)
Cell
, vol.69
, pp. 597-604
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Ray, C.A.1
Black, R.A.2
Kronheim, S.R.3
Greenstreet, T.A.4
Sleath, P.R.5
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