-
1
-
-
0033607768
-
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
-
Masumoto, J., Taniguchi, S., Ayukawa, K., Sarvotham, H., Kishino, T., Niikawa, N., Hidaka, E., Katsuyama, T., Higuchi, T., and Sagara, J. (1999) ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells, J. Biol. Chem. 274, 33835-33838.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33835-33838
-
-
Masumoto, J.1
Taniguchi, S.2
Ayukawa, K.3
Sarvotham, H.4
Kishino, T.5
Niikawa, N.6
Hidaka, E.7
Katsuyama, T.8
Higuchi, T.9
Sagara, J.10
-
2
-
-
0033676843
-
TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers
-
Conway, K. E., McConnell, B. B., Bowring, C. E., Donald, C. D., Warren, S. T., and Vertino, P. M. (2000) TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers, Cancer Res. 60, 6236-6242.
-
(2000)
Cancer Res.
, vol.60
, pp. 6236-6242
-
-
Conway, K.E.1
McConnell, B.B.2
Bowring, C.E.3
Donald, C.D.4
Warren, S.T.5
Vertino, P.M.6
-
3
-
-
0033709108
-
Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1
-
McConnell, B. B., and Vertino, P. M. (2000) Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1, Cancer Res. 60, 6243-6247.
-
(2000)
Cancer Res.
, vol.60
, pp. 6243-6247
-
-
McConnell, B.B.1
Vertino, P.M.2
-
4
-
-
0034804347
-
Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomenzation of ASC
-
Masumoto, J., Taniguchi, S., and Sagara, J. (2001) Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomenzation of ASC, Biochem. Biophys. Res. Commun. 280, 652-655.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 652-655
-
-
Masumoto, J.1
Taniguchi, S.2
Sagara, J.3
-
5
-
-
0035914452
-
Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis
-
Richards, N., Schaner, P., Diaz, A., Stuckey, J., Shelden, E., and Wadhwat, A., and Gumucio, D. L. (2001) Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis, J. Biol. Chem. 276, 39320-39329.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39320-39329
-
-
Richards, N.1
Schaner, P.2
Diaz, A.3
Stuckey, J.4
Shelden, E.5
Wadhwat, A.6
Gumucio, D.L.7
-
6
-
-
0037121940
-
The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways
-
Stehlik, C., Florentino, L., Dorfleutner, A., Bruey, J., Ariza, M., Sagara, J., and Reed J. C. (2002) The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways, J. Exp. Med. 196, 1605-1615.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1605-1615
-
-
Stehlik, C.1
Florentino, L.2
Dorfleutner, A.3
Bruey, J.4
Ariza, M.5
Sagara, J.6
Reed, J.C.7
-
7
-
-
0037192793
-
PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B
-
Manji, G., Wang, L., Geddes, B. J., Brown, M., Merriam, S., AlGarawi, A., Mak, S., Lora, J. M., Briskin, M., Jurman, M., Cao, J., DiStefano, P. S., and Bertin, J. (2002) PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B, J. Biol. Chem. 277, 115701-11575.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 115701-211575
-
-
Manji, G.1
Wang, L.2
Geddes, B.J.3
Brown, M.4
Merriam, S.5
Algarawi, A.6
Mak, S.7
Lora, J.M.8
Briskin, M.9
Jurman, M.10
Cao, J.11
DiStefano, P.S.12
Bertin, J.13
-
8
-
-
0034857603
-
The PYRIN domain: A member of the death domain-fold superfamily
-
Fairbrother, W. J., Gordon, N. C., Humke, E. W., O'Rourke, K. M., Starovasnik, M. A., Yin, J. P., and Dixit, V. M. (2001) The PYRIN domain: a member of the death domain-fold superfamily. Protein Sci. 10, 1911-1918.
-
(2001)
Protein Sci.
, vol.10
, pp. 1911-1918
-
-
Fairbrother, W.J.1
Gordon, N.C.2
Humke, E.W.3
O'Rourke, K.M.4
Starovasnik, M.A.5
Yin, J.P.6
Dixit, V.M.7
-
9
-
-
0034520137
-
The PYRIN domain: A novel motif found in apoptosis and inflammation proteins
-
Bertin, J., and DiStefano, P. S. (2000) The PYRIN domain: a novel motif found in apoptosis and inflammation proteins, Cell Death Differ. 7, 1273-1274.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1273-1274
-
-
Bertin, J.1
Distefano, P.S.2
-
10
-
-
0035253123
-
PAAD - A new protein domain associated with apoptosis, cancer and autoimmune diseases
-
Pawlowski, K., Pio, F., Chu, Z., Reed, J. C., and Godzik, A. (2001) PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem. Sci. 26, 85-87.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 85-87
-
-
Pawlowski, K.1
Pio, F.2
Chu, Z.3
Reed, J.C.4
Godzik, A.5
-
11
-
-
0035253022
-
The DAPIN family: A novel domain links apoptotic and interferon response proteins
-
Staub, E., Dahl, E., and Rosenthal, A. (2001) The DAPIN family: a novel domain links apoptotic and interferon response proteins, Trends Biochem. Sci. 26, 83-85.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 83-85
-
-
Staub, E.1
Dahl, E.2
Rosenthal, A.3
-
12
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon, F., Burns, K., and Tschopp, J. (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta, Mol. Cell 10, 417-426.
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
13
-
-
0037077283
-
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
-
Srinivasula, S. M., Poyet, J. L., Razmara, M., Datta, P., Zhang, Z., and Alnemri, E. S. (2002) The PYRIN-CARD protein ASC is an activating adaptor for caspase-1, J. Biol. Chem. 277, 21119-21122.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21119-21122
-
-
Srinivasula, S.M.1
Poyet, J.L.2
Razmara, M.3
Datta, P.4
Zhang, Z.5
Alnemri, E.S.6
-
14
-
-
0344585401
-
Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation
-
Stehlik, C., Lee, S. H., Dorfleutner, A., Stassinopoulos, A., Sagara, J., and Reed, J. C. (2003) Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation, J. Immunol. 171, 6154-6163.
-
(2003)
J. Immunol.
, vol.171
, pp. 6154-6163
-
-
Stehlik, C.1
Lee, S.H.2
Dorfleutner, A.3
Stassinopoulos, A.4
Sagara, J.5
Reed, J.C.6
-
15
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
Mariathasan, S., Newton, K., Monack, D. M., Vucic, D., French, D. M., Lee, W. P., Roose-Girma, M., Erickson, S., and Dixit, V. M. (2004) Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf, Nature 430, 213-218.
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
16
-
-
0033613143
-
Caspase activation: The induced-proximity model
-
Salvesen, G. S., and Dixit, V. M. (1999) Caspase activation: the induced-proximity model. Proc. Natl. Acad. Sci., U.S.A. 96, 10964-10967.
-
(1999)
Proc. Natl. Acad. Sci., U.S.A.
, vol.96
, pp. 10964-10967
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
17
-
-
0033011560
-
Prodomains - Adaptors - oligomerization: The pursuit of caspase activation in apoptosis
-
Kumar, S., and Colussi, P. A. (1999) Prodomains - adaptors - oligomerization: the pursuit of caspase activation in apoptosis, Trends Biochem. Sci. 24, 1-4.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 1-4
-
-
Kumar, S.1
Colussi, P.A.2
-
18
-
-
0042386425
-
The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
-
Liepinish, E., Barbais, R., Dahl, E., Sharipo, A., Staub, E., and Otting, G. (2003) The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition, J. Mol. Biol. 332, 1155-1163.
-
(2003)
J. Mol. Biol.
, vol.332
, pp. 1155-1163
-
-
Liepinish, E.1
Barbais, R.2
Dahl, E.3
Sharipo, A.4
Staub, E.5
Otting, G.6
-
19
-
-
0141817846
-
NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain
-
Miller, S., Kohl, A., Fiorito, F., Herrmann, T., Wider, G., Tschopp, J., Grütter, M. G., and Wüthrich, K. (2003) NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain. Structitre 11, 1199-1205.
-
(2003)
Structitre
, vol.11
, pp. 1199-1205
-
-
Miller, S.1
Kohl, A.2
Fiorito, F.3
Herrmann, T.4
Wider, G.5
Tschopp, J.6
Grütter, M.G.7
Wüthrich, K.8
-
20
-
-
0032101371
-
Death-effector filaments: Novel cytoplasmic structures that recruit caspases and trigger apoptosis
-
Siegel R. M., Martin, D. A., Zheng, L., Ng, S., Bertin, J., Cohen, J., and Lenardo, M. J. (1998) Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis, J. Cell Biol. 141, 1243-1253.
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1243-1253
-
-
Siegel, R.M.1
Martin, D.A.2
Zheng, L.3
Ng, S.4
Bertin, J.5
Cohen, J.6
Lenardo, M.J.7
-
21
-
-
0032100771
-
E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE
-
Perez, D., and White, E. (1998) E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE, J. Cell Biol. 141, 1255-1266.
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1255-1266
-
-
Perez, D.1
White, E.2
-
22
-
-
0033537887
-
mE10, a novel caspase recruitment domain-containing proapoptotic molecule
-
Yan, M., Lee, J., Schilbach, S., Godard, A., and Dexit, V. (1999) mE10, a novel caspase recruitment domain-containing proapoptotic molecule, J. Biol. Chem. 274, 10287-10292.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10287-10292
-
-
Yan, M.1
Lee, J.2
Schilbach, S.3
Godard, A.4
Dexit, V.5
-
23
-
-
0034688996
-
Caspase recruitment domain (CARD)-dependent cytoplasmic filaments mediate bcl10-induced NF-kappaB activation
-
Guiet, C., and Vito, P. (2000) Caspase recruitment domain (CARD)-dependent cytoplasmic filaments mediate bcl10-induced NF-kappaB activation, J. Cell. Biol. 148, 1131-1139.
-
(2000)
J. Cell. Biol.
, vol.148
, pp. 1131-1139
-
-
Guiet, C.1
Vito, P.2
-
24
-
-
0025847213
-
A simple and rapid method for generating a deletion by PCR
-
Imai, Y., Matsushima, Y., Sugimura, T., and Terada, M. (1991) A simple and rapid method for generating a deletion by PCR, Nucleic Acids Res. 19, 2785.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 2785
-
-
Imai, Y.1
Matsushima, Y.2
Sugimura, T.3
Terada, M.4
-
25
-
-
0034601780
-
Interaction of the Escherichia coli replication terminator protein (Tus) with DNA: A model derived from DNA-binding studies of mutant proteins by surface plasmon resonance
-
Neylon, C., Brown, S. E., Kralicek, A. V., Miles, C. S., Love, C. A., and Dixon, N. E. (2000) Interaction of the Escherichia coli replication terminator protein (Tus) with DNA: a model derived from DNA-binding studies of mutant proteins by surface plasmon resonance, Biochemistry 39, 11989-11999.
-
(2000)
Biochemistry
, vol.39
, pp. 11989-11999
-
-
Neylon, C.1
Brown, S.E.2
Kralicek, A.V.3
Miles, C.S.4
Love, C.A.5
Dixon, N.E.6
-
26
-
-
0025283867
-
Use of T7 RNA polymerase to direct expression of cloned genes
-
Studier, F. W., Rosenberg, A. H., Dunn, J. J., and Dubendorff, J. W. (1990) Use of T7 RNA polymerase to direct expression of cloned genes, Methods Enzymol. 185, 60-89.
-
(1990)
Methods Enzymol.
, vol.185
, pp. 60-89
-
-
Studier, F.W.1
Rosenberg, A.H.2
Dunn, J.J.3
Dubendorff, J.W.4
-
27
-
-
0028063876
-
Determination of the nuclear magnetic resonance structure of the DNA-binding domain of the P22 c2 repressor (1-76) in solution and comparison with the DNA-binding domain of the 434 repressor
-
Sevilla-Sierra, P., Otting, G., and Wüthrich, K. (1994) Determination of the nuclear magnetic resonance structure of the DNA-binding domain of the P22 c2 repressor (1-76) in solution and comparison with the DNA-binding domain of the 434 repressor, J. Mol. Biol. 235, 1003-1020.
-
(1994)
J. Mol. Biol.
, vol.235
, pp. 1003-1020
-
-
Sevilla-Sierra, P.1
Otting, G.2
Wüthrich, K.3
-
28
-
-
0033601077
-
Three-dimensional structure of a complex between the death domains of Pelle and Tube
-
Xiao, T., Towb, P., Wasserman, S. A., and Sprang, S. R. (1999) Three-dimensional structure of a complex between the death domains of Pelle and Tube, Cell 99, 545-555.
-
(1999)
Cell
, vol.99
, pp. 545-555
-
-
Xiao, T.1
Towb, P.2
Wasserman, S.A.3
Sprang, S.R.4
-
29
-
-
0033542482
-
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
-
Qin, H., Srinivasula, S. M., Wu, G:, Fernandes-Alnemri, T., Alnemri, E. S., and Shi, Y. (1999) Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1, Nature 399, 549-557.
-
(1999)
Nature
, vol.399
, pp. 549-557
-
-
Qin, H.1
Srinivasula, S.M.2
Wu, G.3
Fernandes-Alnemri, T.4
Alnemri, E.S.5
Shi, Y.6
-
30
-
-
0042512008
-
Homology modeling provides insights into the binding mode of the PAAD/ DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family
-
Liu, T., Rojas, A., Ye, Y., and Godzik, A. (2003) Homology modeling provides insights into the binding mode of the PAAD/ DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family, Protein Sci. 12, 1872-1881.
-
(2003)
Protein Sci.
, vol.12
, pp. 1872-1881
-
-
Liu, T.1
Rojas, A.2
Ye, Y.3
Godzik, A.4
-
31
-
-
0037216780
-
The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations
-
Hull, K. M., Shoham, N., Chae, J. J., Aksentijevich, I., and Kastner, D. L. (2003) The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations, Curr. Opin. Rheumatol. 15, 61-69.
-
(2003)
Curr. Opin. Rheumatol.
, vol.15
, pp. 61-69
-
-
Hull, K.M.1
Shoham, N.2
Chae, J.J.3
Aksentijevich, I.4
Kastner, D.L.5
-
32
-
-
0032563323
-
Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment
-
Chou, J. J., Matsuo, H., Duan, H., and Wagner, G. (1998) Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment, Cell 94, 171-180.
-
(1998)
Cell
, vol.94
, pp. 171-180
-
-
Chou, J.J.1
Matsuo, H.2
Duan, H.3
Wagner, G.4
-
33
-
-
0032580153
-
NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment
-
Eberstadt, M., Huane, B., Chen, Z., Meadows, R. P., Ng, S., Zheng, L., Lenardo, M. J., and Fesik, S. W. (1998) NMR structure and mutagenesis of the FADD (Mort1) death-effector domain. Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment. Nature 392, 941-945.
-
(1998)
Nature
, vol.392
, pp. 941-945
-
-
Eberstadt, M.1
Huane, B.2
Chen, Z.3
Meadows, R.P.4
Ng, S.5
Zheng, L.6
Lenardo, M.J.7
Fesik, S.W.8
-
34
-
-
0037349294
-
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
-
Chae, J. J., Komarow, H. D., Cheng, J., Wood, G., Raben, N., Liu, P. P., and Kastner, D. L. (2003) Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis, Mol. Cell 11, 591-604.
-
(2003)
Mol. Cell
, vol.11
, pp. 591-604
-
-
Chae, J.J.1
Komarow, H.D.2
Cheng, J.3
Wood, G.4
Raben, N.5
Liu, P.P.6
Kastner, D.L.7
-
35
-
-
0037436868
-
Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product
-
Dowds, T. A., Masumoto, J., Chen, F. F., Ogura, Y., Inohara, N., and Nunez, G. (2003) Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product, Biochem. Biophys. Res. Commun. 302, 575-580.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.302
, pp. 575-580
-
-
Dowds, T.A.1
Masumoto, J.2
Chen, F.F.3
Ogura, Y.4
Inohara, N.5
Nunez, G.6
-
36
-
-
1642633791
-
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis
-
Ohtsuka, T., Ryu, H., Minamishima, Y. A., Macip, S., Sagara, J., Nakayama, K. I., Aaronson, S. A., and Lee, S. W. (2004) ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis, Nat. Cell Biol. 6, 121-128.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 121-128
-
-
Ohtsuka, T.1
Ryu, H.2
Minamishima, Y.A.3
Macip, S.4
Sagara, J.5
Nakayama, K.I.6
Aaronson, S.A.7
Lee, S.W.8
-
37
-
-
1442277112
-
TMS1/ASC: The cancer connection
-
McConnell, B. B., and Vertino, P. M. (2004) TMS1/ASC: the cancer connection, Apoptosis 9, 5-18.
-
(2004)
Apoptosis
, vol.9
, pp. 5-18
-
-
McConnell, B.B.1
Vertino, P.M.2
|