메뉴 건너뛰기




Volumn 10, Issue 2, 2008, Pages 332-343

Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN; CASPASE INHIBITOR; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MULTIPROTEIN COMPLEX; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHLORIDE; PROTEASOME; PROTEASOME INHIBITOR; SUCROSE;

EID: 38049119726     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2007.01044.x     Document Type: Article
Times cited : (103)

References (67)
  • 1
    • 0023947763 scopus 로고
    • Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor
    • Black, R.A., Kronheim, S.R., Cantrell, M., Deeley, M.C., March, C.J., Prickett, K.S., et al. (1988) Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor. J Biol Chem 263: 9437-9442.
    • (1988) J Biol Chem , vol.263 , pp. 9437-9442
    • Black, R.A.1    Kronheim, S.R.2    Cantrell, M.3    Deeley, M.C.4    March, C.J.5    Prickett, K.S.6
  • 2
    • 31744441475 scopus 로고    scopus 로고
    • Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
    • Boyden, E.D., and Dietrich, W.F. (2006) Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet 38: 240-244.
    • (2006) Nat Genet , vol.38 , pp. 240-244
    • Boyden, E.D.1    Dietrich, W.F.2
  • 3
    • 0033815330 scopus 로고    scopus 로고
    • Salmonella induces macrophage death by caspase-1-dependent necrosis
    • Brennan, M.A., and Cookson, B.T. (2000) Salmonella induces macrophage death by caspase-1-dependent necrosis. Mol Microbiol 38: 31-40.
    • (2000) Mol Microbiol , vol.38 , pp. 31-40
    • Brennan, M.A.1    Cookson, B.T.2
  • 4
    • 0029738195 scopus 로고    scopus 로고
    • A bacterial invasin induces macrophage apoptosis by binding directly to ICE
    • Chen, Y., Smith, M.R., Thirumalai, K., and Zychlinsky, A. (1996) A bacterial invasin induces macrophage apoptosis by binding directly to ICE. EMBO J 15: 3853-3860.
    • (1996) EMBO J , vol.15 , pp. 3853-3860
    • Chen, Y.1    Smith, M.R.2    Thirumalai, K.3    Zychlinsky, A.4
  • 5
    • 0032504212 scopus 로고    scopus 로고
    • Increased mature interleukin-1beta (IL-1beta) secretion from THP-1 cells induced by nigericin is a result of activation of p45 IL-1beta-converting enzyme processing
    • Cheneval, D., Ramage, P., Kastelic, T., Szelestenyi, T., Niggli, H., Hemmig, R., et al. (1998) Increased mature interleukin-1beta (IL-1beta) secretion from THP-1 cells induced by nigericin is a result of activation of p45 IL-1beta-converting enzyme processing. J Biol Chem 273: 17846-17851.
    • (1998) J Biol Chem , vol.273 , pp. 17846-17851
    • Cheneval, D.1    Ramage, P.2    Kastelic, T.3    Szelestenyi, T.4    Niggli, H.5    Hemmig, R.6
  • 6
    • 2442701424 scopus 로고    scopus 로고
    • Anthrax lethal toxin rapidly activates caspase-1/ICE and induces extracellular release of IL-1beta and IL-18
    • Cordoba-Rodriguez, R., Fang, H., Lankford, C.S., and Frucht, D.M. (2004) Anthrax lethal toxin rapidly activates caspase-1/ICE and induces extracellular release of IL-1beta and IL-18. J Biol Chem 279: 20563-20566.
    • (2004) J Biol Chem , vol.279 , pp. 20563-20566
    • Cordoba-Rodriguez, R.1    Fang, H.2    Lankford, C.S.3    Frucht, D.M.4
  • 8
    • 0036001057 scopus 로고    scopus 로고
    • Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells
    • Edgeworth, J.D., Spencer, J., Phalipon, A., Griffin, G.E., and Sansonetti, P.J. (2002) Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells. Eur J Immunol 32: 1464-1471.
    • (2002) Eur J Immunol , vol.32 , pp. 1464-1471
    • Edgeworth, J.D.1    Spencer, J.2    Phalipon, A.3    Griffin, G.E.4    Sansonetti, P.J.5
  • 9
    • 0032909752 scopus 로고    scopus 로고
    • Interleukin-18 and interleukin-1 beta: Two cytokine substrates for ICE (caspase-1)
    • Fantuzzi, G., and Dinarello, C.A. (1999) Interleukin-18 and interleukin-1 beta: Two cytokine substrates for ICE (caspase-1). J Clin Immunol 19: 1-11.
    • (1999) J Clin Immunol , vol.19 , pp. 1-11
    • Fantuzzi, G.1    Dinarello, C.A.2
  • 10
    • 0031201476 scopus 로고    scopus 로고
    • Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages
    • Ferrari, D., Chiozzi, P., Falzoni, S., Dal Susino, M., Melchiorri, L., Baricordi, O.R., et al. (1997) Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages. J Immunol 159: 1451-1458.
    • (1997) J Immunol , vol.159 , pp. 1451-1458
    • Ferrari, D.1    Chiozzi, P.2    Falzoni, S.3    Dal Susino, M.4    Melchiorri, L.5    Baricordi, O.R.6
  • 11
    • 16244362671 scopus 로고    scopus 로고
    • Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
    • Fink, S.L., and Cookson, B.T. (2005) Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells. Infect Immun 73: 1907-1916.
    • (2005) Infect Immun , vol.73 , pp. 1907-1916
    • Fink, S.L.1    Cookson, B.T.2
  • 12
    • 33749576792 scopus 로고    scopus 로고
    • Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
    • Fink, S.L., and Cookson, B.T. (2006) Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell Microbiol 8: 1812-1825.
    • (2006) Cell Microbiol , vol.8 , pp. 1812-1825
    • Fink, S.L.1    Cookson, B.T.2
  • 13
    • 33744464740 scopus 로고    scopus 로고
    • Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
    • Franchi, L., Amer, A., Body-Malapel, M., Kanneganti, T.D., Ozoren, N., Jagirdar, R., et al. (2006) Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol 7: 576-582.
    • (2006) Nat Immunol , vol.7 , pp. 576-582
    • Franchi, L.1    Amer, A.2    Body-Malapel, M.3    Kanneganti, T.D.4    Ozoren, N.5    Jagirdar, R.6
  • 14
    • 0027470890 scopus 로고
    • Characterization of macrophage sensitivity and resistance to anthrax lethal toxin
    • Friedlander, A.M., Bhatnagar, R., Leppla, S.H., Johnson, L., and Singh, Y. (1993) Characterization of macrophage sensitivity and resistance to anthrax lethal toxin. Infect Immun 61: 245-252.
    • (1993) Infect Immun , vol.61 , pp. 245-252
    • Friedlander, A.M.1    Bhatnagar, R.2    Leppla, S.H.3    Johnson, L.4    Singh, Y.5
  • 15
    • 33748598700 scopus 로고    scopus 로고
    • Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
    • Gurcel, L., Abrami, L., Girardin, S., Tschopp, J., and van der Goot, F.G. (2006) Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell 126: 1135-1145.
    • (2006) Cell , vol.126 , pp. 1135-1145
    • Gurcel, L.1    Abrami, L.2    Girardin, S.3    Tschopp, J.4    van der Goot, F.G.5
  • 16
    • 0027097608 scopus 로고
    • Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells
    • Hanna, P.C., Kochi, S., and Collier, R.J. (1992) Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells. Mol Biol Cell 3: 1269-1277.
    • (1992) Mol Biol Cell , vol.3 , pp. 1269-1277
    • Hanna, P.C.1    Kochi, S.2    Collier, R.J.3
  • 18
    • 0030609016 scopus 로고    scopus 로고
    • The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri -induced apoptosis in human monocyte-derived macrophages
    • Hilbi, H., Chen, Y., Thirumalai, K., and Zychlinsky, A. (1997) The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri -induced apoptosis in human monocyte-derived macrophages. Infect Immun 65: 5165-5170.
    • (1997) Infect Immun , vol.65 , pp. 5165-5170
    • Hilbi, H.1    Chen, Y.2    Thirumalai, K.3    Zychlinsky, A.4
  • 19
    • 15644374367 scopus 로고    scopus 로고
    • Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB
    • Hilbi, H., Moss, J.E., Hersh, D., Chen, Y., Arondel, J., Banerjee, S., et al. (1998) Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB. J Biol Chem 273: 32895-32900.
    • (1998) J Biol Chem , vol.273 , pp. 32895-32900
    • Hilbi, H.1    Moss, J.E.2    Hersh, D.3    Chen, Y.4    Arondel, J.5    Banerjee, S.6
  • 20
    • 0033796540 scopus 로고    scopus 로고
    • Tripeptidyl peptidase II promotes maturation of caspase-1 in Shigella flexneri -induced macrophage apoptosis
    • Hilbi, H., Puro, R.J., and Zychlinsky, A. (2000) Tripeptidyl peptidase II promotes maturation of caspase-1 in Shigella flexneri -induced macrophage apoptosis. Infect Immun 68: 5502-5508.
    • (2000) Infect Immun , vol.68 , pp. 5502-5508
    • Hilbi, H.1    Puro, R.J.2    Zychlinsky, A.3
  • 21
    • 1942422683 scopus 로고    scopus 로고
    • Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release
    • Kahlenberg, J.M., and Dubyak, G.R. (2004) Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. Am J Physiol Cell Physiol 286: C1100-C1108.
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Kahlenberg, J.M.1    Dubyak, G.R.2
  • 22
    • 32944462834 scopus 로고    scopus 로고
    • Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
    • Kanneganti, T.D., Ozoren, N., Body-Malapel, M., Amer, A., Park, J.H., Franchi, L., et al. (2006) Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 440: 233-236.
    • (2006) Nature , vol.440 , pp. 233-236
    • Kanneganti, T.D.1    Ozoren, N.2    Body-Malapel, M.3    Amer, A.4    Park, J.H.5    Franchi, L.6
  • 23
    • 13844318262 scopus 로고    scopus 로고
    • Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin
    • Kassam, A., Der, S.D., and Mogridge, J. (2005) Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin. Cell Microbiol 7: 281-292.
    • (2005) Cell Microbiol , vol.7 , pp. 281-292
    • Kassam, A.1    Der, S.D.2    Mogridge, J.3
  • 24
    • 0037470038 scopus 로고    scopus 로고
    • Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha
    • Kim, S.O., Jing, Q., Hoebe, K., Beutler, B., Duesbery, N.S., and Han, J. (2002) Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha. J Biol Chem 278: 7413-7421.
    • (2002) J Biol Chem , vol.278 , pp. 7413-7421
    • Kim, S.O.1    Jing, Q.2    Hoebe, K.3    Beutler, B.4    Duesbery, N.S.5    Han, J.6
  • 25
    • 0346251030 scopus 로고    scopus 로고
    • Anthrax lethal toxin induces human endothelial cell apoptosis
    • Kirby, J.E. (2004) Anthrax lethal toxin induces human endothelial cell apoptosis. Infect Immun 72: 430-439.
    • (2004) Infect Immun , vol.72 , pp. 430-439
    • Kirby, J.E.1
  • 26
    • 0033601241 scopus 로고    scopus 로고
    • ATP treatment of human monocytes promotes caspase-1 maturation and externalization
    • Laliberte, R.E., Eggler, J., and Gabel, C.A. (1999) ATP treatment of human monocytes promotes caspase-1 maturation and externalization. J Biol Chem 274: 36944-36951.
    • (1999) J Biol Chem , vol.274 , pp. 36944-36951
    • Laliberte, R.E.1    Eggler, J.2    Gabel, C.A.3
  • 27
    • 0000947082 scopus 로고
    • Anthrax toxin edema factor: A bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells
    • Leppla, S.H. (1982) Anthrax toxin edema factor: A bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc Natl Acad Sci USA 79: 3162-3166.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 3162-3166
    • Leppla, S.H.1
  • 28
    • 84882897593 scopus 로고    scopus 로고
    • Bacillus anthracis toxins
    • In Alouf, J.E., and Popoff, M. R. (eds). Burlington, MA: Academic Press
    • Leppla, S.H. (2006) Bacillus anthracis toxins. In The Comprehensive Sourcebook of Bacterial Protein Toxins. Alouf, J.E., and Popoff, M. R. (eds). Burlington, MA: Academic Press, pp. 323-347.
    • (2006) The Comprehensive Sourcebook of Bacterial Protein Toxins , pp. 323-347
    • Leppla, S.H.1
  • 29
    • 0031044283 scopus 로고    scopus 로고
    • In vitro and in vivo studies of ICE inhibitors
    • Livingston, D.J. (1997) In vitro and in vivo studies of ICE inhibitors. J Cell Biochem 64: 19-26.
    • (1997) J Cell Biochem , vol.64 , pp. 19-26
    • Livingston, D.J.1
  • 30
    • 0034254559 scopus 로고    scopus 로고
    • Chlamydia trachomatis infection of epithelial cells induces the activation of caspase-1 and release of mature IL-18
    • Lu, H., Shen, C., and Brunham, R.C. (2000) Chlamydia trachomatis infection of epithelial cells induces the activation of caspase-1 and release of mature IL-18. J Immunol 165: 1463-1469.
    • (2000) J Immunol , vol.165 , pp. 1463-1469
    • Lu, H.1    Shen, C.2    Brunham, R.C.3
  • 31
    • 3142654767 scopus 로고    scopus 로고
    • Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
    • Mariathasan, S., Newton, K., Monack, D.M., Vucic, D., French, D.M., Lee, W.P., et al. (2004) Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430: 213-218.
    • (2004) Nature , vol.430 , pp. 213-218
    • Mariathasan, S.1    Newton, K.2    Monack, D.M.3    Vucic, D.4    French, D.M.5    Lee, W.P.6
  • 32
    • 26844452231 scopus 로고    scopus 로고
    • Innate immunity against Francisella tularensis is dependent on the ASC/ caspase-1 axis
    • Mariathasan, S., Weiss, D.S., Dixit, V.M., and Monack, D.M. (2005) Innate immunity against Francisella tularensis is dependent on the ASC/ caspase-1 axis. J Exp Med 202: 1043-1049.
    • (2005) J Exp Med , vol.202 , pp. 1043-1049
    • Mariathasan, S.1    Weiss, D.S.2    Dixit, V.M.3    Monack, D.M.4
  • 34
    • 33845497181 scopus 로고    scopus 로고
    • Inflammatory caspases and inflammasomes: Master switches of inflammation
    • Martinon, F., and Tschopp, J. (2007) Inflammatory caspases and inflammasomes: Master switches of inflammation. Cell Death Differ 14: 10-22.
    • (2007) Cell Death Differ , vol.14 , pp. 10-22
    • Martinon, F.1    Tschopp, J.2
  • 35
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
    • Martinon, F., Burns, K., and Tschopp, J. (2002) The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10: 417-426.
    • (2002) Mol Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 36
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon, F., Petrilli, V., Mayor, A., Tardivel, A., and Tschopp, J. (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440: 237-241.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 37
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
    • Miura, M., Zhu, H., Rotello, R., Hartwieg, E.A., and Yuan, J. (1993) Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75: 653-660.
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hartwieg, E.A.4    Yuan, J.5
  • 38
    • 0035209916 scopus 로고    scopus 로고
    • Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1
    • Monack, D.M., Detweiler, C.S., and Falkow, S. (2001) Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1. Cell Microbiol 3: 825-837.
    • (2001) Cell Microbiol , vol.3 , pp. 825-837
    • Monack, D.M.1    Detweiler, C.S.2    Falkow, S.3
  • 39
    • 0035258849 scopus 로고    scopus 로고
    • Involvement of caspases in apoptotic cell death of murine macrophages infected with A ctinobacillus actinomycetemcomitans
    • Nonaka, K., Ishisaki, A., Okahashi, N., Koseki, T., Kato, S., Muro, M., et al. (2001) Involvement of caspases in apoptotic cell death of murine macrophages infected with A ctinobacillus actinomycetemcomitans. J Periodontal Res 36: 40-47.
    • (2001) J Periodontal Res , vol.36 , pp. 40-47
    • Nonaka, K.1    Ishisaki, A.2    Okahashi, N.3    Koseki, T.4    Kato, S.5    Muro, M.6
  • 40
    • 33646017449 scopus 로고    scopus 로고
    • Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes
    • Ozoren, N., Masumoto, J., Franchi, L., Kanneganti, T.D., Body-Malapel, M., Erturk, I., et al. (2006) Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes. J Immunol 176: 4337-4342.
    • (2006) J Immunol , vol.176 , pp. 4337-4342
    • Ozoren, N.1    Masumoto, J.2    Franchi, L.3    Kanneganti, T.D.4    Body-Malapel, M.5    Erturk, I.6
  • 41
    • 0034049623 scopus 로고    scopus 로고
    • Optimized production and purification of Bacillus anthracis lethal factor
    • Park, S., and Leppla, S.H. (2000) Optimized production and purification of Bacillus anthracis lethal factor. Protein Expr Purif 18: 293-302.
    • (2000) Protein Expr Purif , vol.18 , pp. 293-302
    • Park, S.1    Leppla, S.H.2
  • 42
    • 0032755353 scopus 로고    scopus 로고
    • Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/ IFNgamma-induced release of NO and TNFalpha
    • Pellizzari, R., Guidi-Rontani, C., Vitale, G., Mock, M., and Montecucco, C. (1999) Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha. FEBS Lett 462: 199-204.
    • (1999) FEBS Lett , vol.462 , pp. 199-204
    • Pellizzari, R.1    Guidi-Rontani, C.2    Vitale, G.3    Mock, M.4    Montecucco, C.5
  • 43
    • 0028175838 scopus 로고
    • Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
    • Perregaux, D., and Gabel, C.A. (1994) Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J Biol Chem 269: 15195-15203.
    • (1994) J Biol Chem , vol.269 , pp. 15195-15203
    • Perregaux, D.1    Gabel, C.A.2
  • 44
    • 0026751492 scopus 로고
    • IL-1 beta maturation: Evidence that mature cytokine formation can be induced specifically by nigericin
    • Perregaux, D., Barberia, J., Lanzetti, A.J., Geoghegan, K.F., Carty, T.J., and Gabel, C.A. (1992) IL-1 beta maturation: Evidence that mature cytokine formation can be induced specifically by nigericin. J Immunol 149: 1294-1303.
    • (1992) J Immunol , vol.149 , pp. 1294-1303
    • Perregaux, D.1    Barberia, J.2    Lanzetti, A.J.3    Geoghegan, K.F.4    Carty, T.J.5    Gabel, C.A.6
  • 45
    • 0037087422 scopus 로고    scopus 로고
    • Antimicrobial peptides initiate IL-1 beta posttranslational processing: A novel role beyond innate immunity
    • Perregaux, D.G., Bhavsar, K., Contillo, L., Shi, J., and Gabel, C.A. (2002) Antimicrobial peptides initiate IL-1 beta posttranslational processing: A novel role beyond innate immunity. J Immunol 168: 3024-3032.
    • (2002) J Immunol , vol.168 , pp. 3024-3032
    • Perregaux, D.G.1    Bhavsar, K.2    Contillo, L.3    Shi, J.4    Gabel, C.A.5
  • 46
    • 34548027736 scopus 로고    scopus 로고
    • Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
    • Petrilli, V., Papin, S., Dostert, C., Mayor, A., Martinon, F., and Tschopp, J. (2007) Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 14: 1583-1589.
    • (2007) Cell Death Differ , vol.14 , pp. 1583-1589
    • Petrilli, V.1    Papin, S.2    Dostert, C.3    Mayor, A.4    Martinon, F.5    Tschopp, J.6
  • 48
    • 0036234584 scopus 로고    scopus 로고
    • Production, recovery and immunogenicity of the protective antigen from a recombinant strain of Bacillus anthracis
    • Ramirez, D.M., Leppla, S.H., Schneerson, R., and Shiloach, J. (2002) Production, recovery and immunogenicity of the protective antigen from a recombinant strain of Bacillus anthracis. J Ind Microbiol Biotechnol 28: 232-238.
    • (2002) J Ind Microbiol Biotechnol , vol.28 , pp. 232-238
    • Ramirez, D.M.1    Leppla, S.H.2    Schneerson, R.3    Shiloach, J.4
  • 49
    • 0031080252 scopus 로고    scopus 로고
    • A combinatorial approach for determining protease specificities: Application to interleukin-1beta converting enzyme (ICE)
    • Rano, T.A., Timkey, T., Peterson, E.P., Rotonda, J., Nicholson, D.W., Becker, J.W., etal. (1997) A combinatorial approach for determining protease specificities: Application to interleukin-1beta converting enzyme (ICE). Chem Biol 4: 149-155.
    • (1997) Chem Biol , vol.4 , pp. 149-155
    • Rano, T.A.1    Timkey, T.2    Peterson, E.P.3    Rotonda, J.4    Nicholson, D.W.5    Becker, J.W.6
  • 50
    • 0031875676 scopus 로고    scopus 로고
    • Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11
    • Roberts, J.E., Watters, J.W., Ballard, J.D., and Dietrich, W.F. (1998) Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11. Mol Microbiol 29: 581-591.
    • (1998) Mol Microbiol , vol.29 , pp. 581-591
    • Roberts, J.E.1    Watters, J.W.2    Ballard, J.D.3    Dietrich, W.F.4
  • 51
    • 9544239345 scopus 로고    scopus 로고
    • Involvement of the proteasome in the programmed cell death of NGF- deprived sympathetic neurons
    • Sadoul, R., Fernandez, P.A., Quiquerez, A.L., Martinou, I., Maki, M., Schroter, M., etal. (1996) Involvement of the proteasome in the programmed cell death of NGF- deprived sympathetic neurons. EMBO J 15: 3845-3852.
    • (1996) EMBO J , vol.15 , pp. 3845-3852
    • Sadoul, R.1    Fernandez, P.A.2    Quiquerez, A.L.3    Martinou, I.4    Maki, M.5    Schroter, M.6
  • 52
  • 53
    • 0024392201 scopus 로고
    • Internalization and processing of Bacillus anthracis lethal toxin by toxin-sensitive and -resistant cells
    • Singh, Y., Leppla, S.H., Bhatnagar, R., and Friedlander, A.M. (1989) Internalization and processing of Bacillus anthracis lethal toxin by toxin-sensitive and -resistant cells. J Biol Chem 264: 11099-11102.
    • (1989) J Biol Chem , vol.264 , pp. 11099-11102
    • Singh, Y.1    Leppla, S.H.2    Bhatnagar, R.3    Friedlander, A.M.4
  • 54
    • 25144521276 scopus 로고    scopus 로고
    • Caspase-1 dependent macrophage death induced by Burkholderia pseudomallei
    • Sun, G.W., Lu, J., Pervaiz, S., Cao, W.P., and Gan, Y.H. (2005) Caspase-1 dependent macrophage death induced by Burkholderia pseudomallei. Cell Microbiol 7: 1447-1458.
    • (2005) Cell Microbiol , vol.7 , pp. 1447-1458
    • Sun, G.W.1    Lu, J.2    Pervaiz, S.3    Cao, W.P.4    Gan, Y.H.5
  • 55
    • 0033056295 scopus 로고    scopus 로고
    • Proteasome activity is required for anthrax lethal toxin to kill macrophages
    • Tang, G., and Leppla, S.H. (1999) Proteasome activity is required for anthrax lethal toxin to kill macrophages. Infect Immun 67: 3055-3060.
    • (1999) Infect Immun , vol.67 , pp. 3055-3060
    • Tang, G.1    Leppla, S.H.2
  • 56
    • 0028986623 scopus 로고
    • Interleukin-1 beta converting enzyme: A novel cysteine protease required for IL-1 beta production and implicated in programmed cell death
    • Thornberry, N.A., and Molineaux, S.M. (1995) Interleukin-1 beta converting enzyme: A novel cysteine protease required for IL-1 beta production and implicated in programmed cell death. Protein Sci 4: 3-12.
    • (1995) Protein Sci , vol.4 , pp. 3-12
    • Thornberry, N.A.1    Molineaux, S.M.2
  • 57
    • 0026507126 scopus 로고
    • A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
    • Thornberry, N.A., Bull, H.G., Calaycay, J.R., Chapman, K.T., Howard, A.D., Kostura, M.J., et al. (1992) A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 356: 768-774.
    • (1992) Nature , vol.356 , pp. 768-774
    • Thornberry, N.A.1    Bull, H.G.2    Calaycay, J.R.3    Chapman, K.T.4    Howard, A.D.5    Kostura, M.J.6
  • 58
    • 0037312509 scopus 로고    scopus 로고
    • NALPs: A novel protein family involved in inflammation
    • Tschopp, J., Martinon, F., and Burns, K. (2003) NALPs: A novel protein family involved in inflammation. Nat Rev Mol Cell Biol 4: 95-104.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 95-104
    • Tschopp, J.1    Martinon, F.2    Burns, K.3
  • 59
    • 0031925706 scopus 로고    scopus 로고
    • Internalization of a Bacillus anthracis protective antigen-c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies
    • Varughese, M., Chi, A., Teixeira, A.V., Nicholls, P.J., Keith, J.M., and Leppla, S.H. (1998) Internalization of a Bacillus anthracis protective antigen-c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies. Mol Med 4: 87-95.
    • (1998) Mol Med , vol.4 , pp. 87-95
    • Varughese, M.1    Chi, A.2    Teixeira, A.V.3    Nicholls, P.J.4    Keith, J.M.5    Leppla, S.H.6
  • 60
    • 0345735833 scopus 로고    scopus 로고
    • Salmonella rapidly kill dendritic cells via a caspase-1-dependent mechanism
    • van der Velden, A.W., Velasquez, M., and Starnbach, M.N. (2003) Salmonella rapidly kill dendritic cells via a caspase-1-dependent mechanism. J Immunol 171: 6742-6749.
    • (2003) J Immunol , vol.171 , pp. 6742-6749
    • van der Velden, A.W.1    Velasquez, M.2    Starnbach, M.N.3
  • 61
    • 4844222940 scopus 로고    scopus 로고
    • Maitotoxin induces biphasic interleukin-1beta secretion and membrane blebbing in murine macrophages
    • Verhoef, P.A., Kertesy, S.B., Estacion, M., Schilling, W.P., and Dubyak, G.R. (2004) Maitotoxin induces biphasic interleukin-1beta secretion and membrane blebbing in murine macrophages. Mol Pharmacol 66: 909-920.
    • (2004) Mol Pharmacol , vol.66 , pp. 909-920
    • Verhoef, P.A.1    Kertesy, S.B.2    Estacion, M.3    Schilling, W.P.4    Dubyak, G.R.5
  • 62
    • 0034672216 scopus 로고    scopus 로고
    • Susceptibility of mitogen-activated protein kinase family members to proteolysis by anthrax lethal factor
    • Vitale, G., Bernardi, L., Napolitani, G., Mock, M., and Montecucco, C. (2000) Susceptibility of mitogen-activated protein kinase family members to proteolysis by anthrax lethal factor. Biochem J 352 Part 3: 739-745.
    • (2000) Biochem J , vol.352 , Issue.PART 3 , pp. 739-745
    • Vitale, G.1    Bernardi, L.2    Napolitani, G.3    Mock, M.4    Montecucco, C.5
  • 63
    • 0028989337 scopus 로고
    • Potassium-inhibited processing of IL-1 beta in human monocytes
    • Walev, I., Reske, K., Palmer, M., Valeva, A., and Bhakdi, S. (1995) Potassium-inhibited processing of IL-1 beta in human monocytes. EMBO J 14: 1607-1614.
    • (1995) EMBO J , vol.14 , pp. 1607-1614
    • Walev, I.1    Reske, K.2    Palmer, M.3    Valeva, A.4    Bhakdi, S.5
  • 64
    • 0028107827 scopus 로고
    • Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: A (p20/p10), 2 homodimer
    • Walker, N.P., Talanian, R.V., Brady, K.D., Dang, L.C., Bump, N.J., Ferenz, C.R., et al. (1994) Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: A (p20/p10), 2 homodimer. Cell 78: 343-352.
    • (1994) Cell , vol.78 , pp. 343-352
    • Walker, N.P.1    Talanian, R.V.2    Brady, K.D.3    Dang, L.C.4    Bump, N.J.5    Ferenz, C.R.6
  • 65
    • 0035870628 scopus 로고    scopus 로고
    • Genetic, physical, and transcript map of the Ltxs1 region of mouse chromosome 11
    • Watters, J.W., and Dietrich, W.F. (2001) Genetic, physical, and transcript map of the Ltxs1 region of mouse chromosome 11. Genomics 73: 223-231.
    • (2001) Genomics , vol.73 , pp. 223-231
    • Watters, J.W.1    Dietrich, W.F.2
  • 67
    • 15844393942 scopus 로고    scopus 로고
    • Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme
    • Yamin, T.T., Ayala, J.M., and Miller, D.K. (1996) Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme. J Biol Chem 271: 13273-13282.
    • (1996) J Biol Chem , vol.271 , pp. 13273-13282
    • Yamin, T.T.1    Ayala, J.M.2    Miller, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.