Cutting edge: Cyclic polypeptide and aminoglycoside antibiotics trigger IL-1β secretion by activating the NLRP3 inflammasome

Journal of Immunology

Volumn 186, Issue 5, 2011, Pages 2714-2718

  Allam, Ramanjaneyulu ^a,b   Darisipudi, Murthy Narayana ^a   Rupanagudi, Khader Valli ^a   Lichtnekert, Julia ^a   Tschopp, Jurg ^b   Anders, Hans Joachim ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; CRYOPYRIN; GRAMICIDIN; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NEOMYCIN; POLYMYXIN B; PURINERGIC P2X7 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TYROTHRICIN;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DRUG EFFICACY; IMMUNE RESPONSE; IMMUNOSTIMULATION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PERITONITIS; PHAGOCYTOSIS; POTASSIUM TRANSPORT; PRIORITY JOURNAL;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; BONE MARROW CELLS; CARRIER PROTEINS; DENDRITIC CELLS; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDES, CYCLIC; PERITONITIS; PROTEIN PRECURSORS; RECEPTORS, INTERLEUKIN-1;

EID: 79952747168     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002657     Document Type: Article

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