Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β

Nature Immunology

Volumn 14, Issue 1, 2013, Pages 52-60

  Mishra, Bibhuti B ^a   Rathinam, Vijay A K ^a   Martens, Gregory W ^a   Martinot, Amanda J ^b   Kornfeld, Hardy ^a   Fitzgerald, Katherine A ^a   Sassetti, Christopher M ^a,c  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CRYOPYRIN; GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 1; INTERLEUKIN 1BETA; NITRIC OXIDE; STREPTOMYCIN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; B LYMPHOCYTE; BACTERIAL GROWTH; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNOPATHOLOGY; IN VIVO STUDY; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHIL CHEMOTAXIS; NITROSYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TUBERCULOSIS;

ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; HUMANS; IMMUNITY, INNATE; INFLAMMASOMES; INTERFERON-GAMMA; INTERLEUKIN-1BETA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYCOBACTERIUM TUBERCULOSIS; NITRIC OXIDE; PROTEIN MODIFICATION, TRANSLATIONAL; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; TUBERCULOSIS;

EID: 84871188736     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2474     Document Type: Article

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