-
1
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
Thornberry, N. A. et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 356, 768-774 (1992).
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
-
2
-
-
77950362382
-
The inflammasomes
-
Schroder, K. & Tschopp, J. The inflammasomes. Cell 140, 821-832 (2010).
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
3
-
-
77957554717
-
Molecular mechanism of NLRP3 inflammasome activation
-
Jin, C. & Flavell, R. A. Molecular mechanism of NLRP3 inflammasome activation. J. Clin. Immunol. 30, 628-631 (2010).
-
(2010)
J. Clin. Immunol.
, vol.30
, pp. 628-631
-
-
Jin, C.1
Flavell, R.A.2
-
4
-
-
58049200723
-
Function of Nod-like receptors in microbial recognition and host defense
-
Franchi, L., Warner, N., Viani, K. & Nunez, G. Function of Nod-like receptors in microbial recognition and host defense. Immunol. Rev. 227, 106-128 (2009).
-
(2009)
Immunol. Rev.
, vol.227
, pp. 106-128
-
-
Franchi, L.1
Warner, N.2
Viani, K.3
Nunez, G.4
-
5
-
-
79953813107
-
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
-
Dinarello, C. A. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 117, 3720-3732 (2011).
-
(2011)
Blood
, vol.117
, pp. 3720-3732
-
-
Dinarello, C.A.1
-
6
-
-
0034192466
-
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions
-
Kang, S. J. et al. Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions. J. Cell Biol. 149, 613-622 (2000).
-
(2000)
J. Cell Biol.
, vol.149
, pp. 613-622
-
-
Kang, S.J.1
-
7
-
-
0029808205
-
Identification and characterization of ich-3, a member of the interleukin-1 converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE
-
DOI 10.1074/jbc.271.34.20580
-
Wang, S. et al. Identification and characterization of Ich-3, a member of the interleukin-1b converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE. J. Biol. Chem. 271, 20580-20587 (1996). (Pubitemid 26281835)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.34
, pp. 20580-20587
-
-
Wang, S.1
Miura, M.2
Jung, Y.-K.3
Zhu, H.4
Gagliardini, V.5
Shi, L.6
Greenberg, A.H.7
Yuan, J.8
-
8
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
DOI 10.1016/S0092-8674(00)80943-5
-
Wang, S. et al. Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 92, 501-509 (1998). (Pubitemid 28101113)
-
(1998)
Cell
, vol.92
, Issue.4
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.-K.3
Zhu, H.4
Li, E.5
Yuan, J.6
-
9
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1b converting enzyme
-
Kuida, K. et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1b converting enzyme. Science 267, 2000-2003 (1995).
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
-
10
-
-
0028984948
-
Mice deficient in IL-1b-converting enzyme are defective in production of mature IL-1b and resistant to endotoxic shock
-
Li, P. et al. Mice deficient in IL-1b-converting enzyme are defective in production of mature IL-1b and resistant to endotoxic shock. Cell 80, 401-411 (1995).
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
-
11
-
-
34548699677
-
The role of the inflammasome in cellular responses to toxins and bacterial effectors
-
DOI 10.1007/s00281-007-0085-0, The NLR-related Disorders
-
Freche, B., Reig, N. & van der Goot, F. G. The role of the inflammasome in cellular responses to toxins and bacterial effectors. Semin. Immunopathol. 29, 249-260 (2007). (Pubitemid 47416223)
-
(2007)
Seminars in Immunopathology
, vol.29
, Issue.3
, pp. 249-260
-
-
Freche, B.1
Reig, N.2
Van Der Goot, F.G.3
-
12
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
DOI 10.1038/ng1724, PII NG1724
-
Boyden,E.D.&Dietrich,W.F.Nalp1bcontrolsmousemacrophage susceptibilityto anthrax lethal toxin. Nature Genet. 38, 240-244 (2006). (Pubitemid 43177241)
-
(2006)
Nature Genetics
, vol.38
, Issue.2
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
13
-
-
77955482224
-
Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome
-
Ng, J.et al. Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome. Gastroenterology, 139, 542-552 (2010).
-
(2010)
Gastroenterology
, vol.139
, pp. 542-552
-
-
Ng, J.1
-
14
-
-
77956397771
-
Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis
-
Dunne, A. et al. Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis. J. Immunol. 185, 1711-1719 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 1711-1719
-
-
Dunne, A.1
-
15
-
-
76249108958
-
Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1b, depending on listeriolysin O and NLRP3
-
Meixenberger, K. et al. Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1b, depending on listeriolysin O and NLRP3. J. Immunol. 184, 922-930 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 922-930
-
-
Meixenberger, K.1
-
16
-
-
77954316475
-
Structure biological functions and applications of the AB5 toxins
-
Beddoe, T., Paton, A.W., LeNours, J., Rossjohn, J. & Paton, J.C. Structure, biological functions and applications of the AB5 toxins. Trends Biochem. Sci. 35, 411-418 (2010).
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 411-418
-
-
Beddoe, T.1
Paton, A.W.2
Lenours, J.3
Rossjohn, J.4
Paton, J.C.5
-
17
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
DOI 10.1038/nature04515, PII N04515
-
Mariathasan, S. et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440, 228-232 (2006). (Pubitemid 43372102)
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
18
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
DOI 10.1038/nature02664
-
Mariathasan, S. et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430, 213-218 (2004). (Pubitemid 38902430)
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 213-218
-
-
Mariathasan, S.1
Hewton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
19
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri, T., Yu, J. W., Datta, P., Wu, J. & Alnemri, E. S. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458, 509-513 (2009).
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
20
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung, V. et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458, 514-518 (2009).
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
-
21
-
-
0035808396
-
7 receptors
-
DOI 10.1074/jbc.M006781200
-
Solle, M. et al. Altered cytokine production in mice lacking P2X7 receptors. J. Biol. Chem. 276, 125-132 (2001). (Pubitemid 32050297)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.1
, pp. 125-132
-
-
Solle, M.1
Labasi, J.2
Perregaux, D.G.3
Stam, E.4
Petrushova, N.5
Koller, B.H.6
Griffiths, R.J.7
Gabel, C.A.8
-
22
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
DOI 10.1038/nature04516, PII N04516
-
Martinon, F., Petrilli, V., Mayor, A., Tardivel, A. & Tschopp, J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440, 237-241 (2006). (Pubitemid 43372104)
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
23
-
-
77954521853
-
Pathogenic Vibrio activate NLRP3 inflammasomevia cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kB signaling
-
Toma,C.etal.Pathogenic Vibrio activate NLRP3 inflammasomevia cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kB signaling. J. Immunol. 184, 5287-5297 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 5287-5297
-
-
Toma, C.1
-
24
-
-
0036671894
-
The Inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL
-
DOI 10.1016/S1097-2765(02)00599-3
-
Martinon, F., Burns, K. & Tschopp, J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing ofproIL-b. Mol. Cell 10, 417-426 (2002). (Pubitemid 35007355)
-
(2002)
Molecular Cell
, vol.10
, Issue.2
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
25
-
-
38049119726
-
Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome
-
Wickliffe, K. E., Leppla, S. H. & Moayeri, M. Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome. Cell. Microbiol. 10, 332-343 (2008).
-
(2008)
Cell. Microbiol.
, vol.10
, pp. 332-343
-
-
Wickliffe, K.E.1
Leppla, S.H.2
Moayeri, M.3
-
26
-
-
0031004174
-
Caspase-1 processes IFN-c-inducing factor and regulates LPS-induced IFN-c production
-
DOI 10.1038/386619a0
-
Ghayur, T. et al. Caspase-1 processes IFN-c-inducing factor and regulates LPS-induced IFN-c production. Nature 386, 619-623 (1997). (Pubitemid 27175429)
-
(1997)
Nature
, vol.386
, Issue.6625
, pp. 619-623
-
-
Ghayur, T.1
Banerjee, S.2
Hugunin, M.3
Butler, D.4
Herzog, L.5
Carter, A.6
Quintal, L.7
Sekut, L.8
Talanian, R.9
Paskind, M.10
Wong, W.11
Kamen, R.12
Tracey, D.13
Allen, H.14
-
27
-
-
15644369352
-
Activation of interferon-c inducing factor mediated by interleukin-1 converting enzyme
-
DOI 10.1126/science.275.5297.206
-
Gu, Y. et al. Activation of interferon-c inducing factor mediated by interleukin-1b converting enzyme. Science 275, 206-209 (1997). (Pubitemid 27034760)
-
(1997)
Science
, vol.275
, Issue.5297
, pp. 206-209
-
-
Gu, Y.1
Kuida, K.2
Tsutsui, H.3
Ku, G.4
Hsiao, K.5
Fleming, M.A.6
Hayashi, N.7
Higashino, K.8
Okamura, H.9
Nakanishi, K.10
Kurimoto, M.11
Tanimoto, T.12
Flavell, R.A.13
Sato, V.14
Harding, M.W.15
Livingston, D.J.16
Su, M.S.-S.17
-
28
-
-
80052754179
-
Caspase-1 promiscuity is counterbalanced by rapid inactivation of processed enzyme
-
Walsh, J. G., Logue, S. E., Luthi, A. U. & Martin, S. J. Caspase-1 promiscuity is counterbalanced by rapid inactivation of processed enzyme. J. Biol. Chem. 286, 32513-32524 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 32513-32524
-
-
Walsh, J.G.1
Logue, S.E.2
Luthi, A.U.3
Martin, S.J.4
-
29
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala, F. S. et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24, 317-327 (2006).
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
-
30
-
-
77958125448
-
Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia
-
Lamkanfi, M. et al. Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia. J. Immunol. 185, 4385-4392 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 4385-4392
-
-
Lamkanfi, M.1
-
31
-
-
77953116282
-
Absentinmelanoma2isrequired for innate immune recognition of Francisella tularensis
-
Jones,J.W.etal. Absentinmelanoma2isrequired for innate immune recognition of Francisella tularensis. Proc. Natl Acad. Sci. USA 107, 9771-9776 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 9771-9776
-
-
Jones, J.W.1
-
32
-
-
79958034097
-
Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation
-
Qu, Y. et al. Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation. J. Immunol. 186, 6553-6561 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 6553-6561
-
-
Qu, Y.1
-
33
-
-
26644453335
-
Simple and highly efficient BAC recombineering using galK selection
-
Warming, S., Costantino, N., Court,D.L., Jenkins,N.A.&Copeland,N.G. Simple and highly efficient BAC recombineering using galK selection. Nucleic Acids Res. 33, e36 (2005).
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Warming, S.1
Costantino, N.2
Court, D.L.3
Jenkins, N.A.4
Copeland, N.G.5
-
34
-
-
0035308590
-
A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
-
Lee, E. C. et al. A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 73, 56-65 (2001).
-
(2001)
Genomics
, vol.73
, pp. 56-65
-
-
Lee, E.C.1
-
35
-
-
70349977406
-
Generating transgenic mice from bacterial artificial chromosomes: Transgenesis efficiency, integration and expression outcomes
-
Van Keuren, M. L., Gavrilina, G. B., Filipiak, W. E., Zeidler, M. G. & Saunders, T. L. Generating transgenic mice from bacterial artificial chromosomes: transgenesis efficiency, integration and expression outcomes. Transgenic Res. 18, 769-785 (2009).
-
(2009)
Transgenic Res.
, vol.18
, pp. 769-785
-
-
Van Keuren, M.L.1
Gavrilina, G.B.2
Filipiak, W.E.3
Zeidler, M.G.4
Saunders, T.L.5
|