-
1
-
-
0036671894
-
The Inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-1b
-
10.1016/S1097-2765(02)00599-3. 12191486
-
The Inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-1b. F Martinon K Burns J Tschopp, Mol Cell 2002 10 417 426 10.1016/S1097-2765(02)00599-3 12191486
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
2
-
-
0031739525
-
Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme
-
10.1111/j.1749-6632.1998.tb08307.x. 9917859
-
Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme. CA Dinarello, Ann N Y Acad Sci 1998 856 1 11 10.1111/j.1749-6632.1998. tb08307.x 9917859
-
(1998)
Ann N y Acad Sci
, vol.856
, pp. 1-11
-
-
Dinarello, C.A.1
-
3
-
-
39749084641
-
Active caspase 1 is a regulator of unconventional protein secretion
-
10.1016/j.cell.2007.12.040. 18329368
-
Active caspase 1 is a regulator of unconventional protein secretion. M Keller A Ruegg S Werner HD Beer, Cell 2008 132 818 831 10.1016/j.cell.2007.12. 040 18329368
-
(2008)
Cell
, vol.132
, pp. 818-831
-
-
Keller, M.1
Ruegg, A.2
Werner, S.3
Beer, H.D.4
-
4
-
-
37549002511
-
The caspase 1 digestome identifies the glycolysis pathway as a target during infection and septic shock
-
10.1074/jbc.M708182200. 17959595
-
The caspase 1 digestome identifies the glycolysis pathway as a target during infection and septic shock. W Shao G Yeretssian K Doiron SN Hussain M Saleh, J Biol Chem 2007 282 36321 36329 10.1074/jbc.M708182200 17959595
-
(2007)
J Biol Chem
, vol.282
, pp. 36321-36329
-
-
Shao, W.1
Yeretssian, G.2
Doiron, K.3
Hussain, S.N.4
Saleh, M.5
-
5
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
10.1146/annurev.immunol.021908.132612. 19302047
-
Immunological and inflammatory functions of the interleukin-1 family. CA Dinarello, Annu Rev Immunol 2009 27 519 550 10.1146/annurev.immunol.021908. 132612 19302047
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
6
-
-
66749174867
-
The inflammasomes: Guardians of the body
-
10.1146/annurev.immunol.021908.132715. 19302040
-
The inflammasomes: guardians of the body. F Martinon A Mayor J Tschopp, Annu Rev Immunol 2009 27 229 265 10.1146/annurev.immunol.021908.132715 19302040
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 229-265
-
-
Martinon, F.1
Mayor, A.2
Tschopp, J.3
-
7
-
-
58049202273
-
Inflammasomes: Guardians of cytosolic sanctity
-
10.1111/j.1600-065X.2008.00730.x. 19120479
-
Inflammasomes: guardians of cytosolic sanctity. M Lamkanfi VM Dixit, Immunol Rev 2009 227 95 105 10.1111/j.1600-065X.2008.00730.x 19120479
-
(2009)
Immunol Rev
, vol.227
, pp. 95-105
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
8
-
-
33344476398
-
CATERPILLERs, pyrin and hereditary immunological disorders
-
10.1038/nri1788. 16498449
-
CATERPILLERs, pyrin and hereditary immunological disorders. JP Ting DL Kastner HM Hoffman, Nat Rev Immunol 2006 6 183 195 10.1038/nri1788 16498449
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 183-195
-
-
Ting, J.P.1
Kastner, D.L.2
Hoffman, H.M.3
-
9
-
-
33747191203
-
The inflammasome: First line of the immune response to cell stress
-
10.1016/j.cell.2006.08.002. 16923387
-
The inflammasome: first line of the immune response to cell stress. Y Ogura FS Sutterwala RA Flavell, Cell 2006 126 659 662 10.1016/j.cell.2006.08.002 16923387
-
(2006)
Cell
, vol.126
, pp. 659-662
-
-
Ogura, Y.1
Sutterwala, F.S.2
Flavell, R.A.3
-
10
-
-
60749104683
-
The inflammasome: A caspase 1-activation platform that regulates immune responses and disease pathogenesis
-
10.1038/ni.1703. 19221555
-
The inflammasome: a caspase 1-activation platform that regulates immune responses and disease pathogenesis. L Franchi T Eigenbrod R Munoz-Planillo G Nunez, Nat Immunol 2009 10 241 247 10.1038/ni.1703 19221555
-
(2009)
Nat Immunol
, vol.10
, pp. 241-247
-
-
Franchi, L.1
Eigenbrod, T.2
Munoz-Planillo, R.3
Nunez, G.4
-
11
-
-
40449140937
-
The NLR gene family: A standard nomenclature
-
10.1016/j.immuni.2008.02.005. 18341998
-
The NLR gene family: a standard nomenclature. JP Ting RC Lovering ES Alnemri J Bertin JM Boss BK Davis RA Flavell SE Girardin A Godzik JA Harton,, et al. Immunity 2008 28 285 287 10.1016/j.immuni.2008.02.005 18341998
-
(2008)
Immunity
, vol.28
, pp. 285-287
-
-
Ting, J.P.1
Lovering, R.C.2
Alnemri, E.S.3
Bertin, J.4
Boss, J.M.5
Davis, B.K.6
Flavell, R.A.7
Girardin, S.E.8
Godzik, A.9
Harton, J.A.10
-
12
-
-
34249941913
-
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling
-
10.1073/pnas.0611496104. 17483456
-
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling. JA Duncan DT Bergstralh Y Wang SB Willingham Z Ye AG Zimmermann JP Ting, Proc Natl Acad Sci USA 2007 104 8041 8046 10.1073/pnas.0611496104 17483456
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8041-8046
-
-
Duncan, J.A.1
Bergstralh, D.T.2
Wang, Y.3
Willingham, S.B.4
Ye, Z.5
Zimmermann, A.G.6
Ting, J.P.7
-
13
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase 1 activation
-
10.1016/j.molcel.2007.01.032. 17349957
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase 1 activation. B Faustin L Lartigue JM Bruey F Luciano E Sergienko B Bailly-Maitre N Volkmann D Hanein I Rouiller JC Reed, Mol Cell 2007 25 713 724 10.1016/j.molcel.2007.01.032 17349957
-
(2007)
Mol Cell
, vol.25
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.M.3
Luciano, F.4
Sergienko, E.5
Bailly-Maitre, B.6
Volkmann, N.7
Hanein, D.8
Rouiller, I.9
Reed, J.C.10
-
15
-
-
0344585401
-
Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase 1 activation
-
14634131
-
Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase 1 activation. C Stehlik SH Lee A Dorfleutner A Stassinopoulos J Sagara JC Reed, J Immunol 2003 171 6154 6163 14634131
-
(2003)
J Immunol
, vol.171
, pp. 6154-6163
-
-
Stehlik, C.1
Lee, S.H.2
Dorfleutner, A.3
Stassinopoulos, A.4
Sagara, J.5
Reed, J.C.6
-
16
-
-
3142654767
-
Differential activation of the inflammasome by caspase 1 adaptors ASC and Ipaf
-
10.1038/nature02664. 15190255
-
Differential activation of the inflammasome by caspase 1 adaptors ASC and Ipaf. S Mariathasan K Newton DM Monack D Vucic DM French WP Lee M Roose-Girma S Erickson VM Dixit, Nature 2004 430 213 218 10.1038/nature02664 15190255
-
(2004)
Nature
, vol.430
, pp. 213-218
-
-
Mariathasan, S.1
Newton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
17
-
-
7944231451
-
ASC is essential for LPS-induced activation of procaspase 1 independently of TLR-associated signal adaptor molecules
-
10.1111/j.1365-2443.2004.00789.x. 15507117
-
ASC is essential for LPS-induced activation of procaspase 1 independently of TLR-associated signal adaptor molecules. M Yamamoto K Yaginuma H Tsutsui J Sagara X Guan E Seki K Yasuda M Yamamoto S Akira K Nakanishi,, et al. Genes Cells 2004 9 1055 1067 10.1111/j.1365-2443.2004.00789.x 15507117
-
(2004)
Genes Cells
, vol.9
, pp. 1055-1067
-
-
Yamamoto, M.1
Yaginuma, K.2
Tsutsui, H.3
Sagara, J.4
Guan, X.5
Seki, E.6
Yasuda, K.7
Yamamoto, M.8
Akira, S.9
Nakanishi, K.10
-
18
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase 1
-
10.1016/j.immuni.2006.02.004. 16546100
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase 1. FS Sutterwala Y Ogura M Szczepanik M Lara-Tejero GS Lichtenberger EP Grant J Bertin AJ Coyle JE Galan PW Askenase RA Flavell, Immunity 2006 24 317 327 10.1016/j.immuni.2006.02.004 16546100
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
Bertin, J.7
Coyle, A.J.8
Galan, J.E.9
Askenase, P.W.10
Flavell, R.A.11
-
19
-
-
35348934890
-
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
-
10.1016/j.molcel.2007.08.029. 17964261
-
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants. JW Yu T Fernandes-Alnemri P Datta J Wu C Juliana L Solorzano M McCormick Z Zhang ES Alnemri, Mol Cell 2007 28 214 227 10.1016/j.molcel.2007.08.029 17964261
-
(2007)
Mol Cell
, vol.28
, pp. 214-227
-
-
Yu, J.W.1
Fernandes-Alnemri, T.2
Datta, P.3
Wu, J.4
Juliana, C.5
Solorzano, L.6
McCormick, M.7
Zhang, Z.8
Alnemri, E.S.9
-
20
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
10.1038/ni.1702. 19158679
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. T Burckstummer C Baumann S Bluml E Dixit G Durnberger H Jahn M Planyavsky M Bilban J Colinge KL Bennett G Superti-Furga, Nat Immunol 2009 10 266 272 10.1038/ni.1702 19158679
-
(2009)
Nat Immunol
, vol.10
, pp. 266-272
-
-
Burckstummer, T.1
Baumann, C.2
Bluml, S.3
Dixit, E.4
Durnberger, G.5
Jahn, H.6
Planyavsky, M.7
Bilban, M.8
Colinge, J.9
Bennett, K.L.10
Superti-Furga, G.11
-
21
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
10.1038/nature07710. 19158676
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. T Fernandes-Alnemri JW Yu P Datta J Wu ES Alnemri, Nature 2009 458 509 513 10.1038/nature07710 19158676
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
22
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase 1-activating inflammasome with ASC
-
10.1038/nature07725. 19158675
-
AIM2 recognizes cytosolic dsDNA and forms a caspase 1-activating inflammasome with ASC. V Hornung A Ablasser M Charrel-Dennis F Bauernfeind G Horvath DR Caffrey E Latz KA Fitzgerald, Nature 2009 458 514 518 10.1038/nature07725 19158675
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Latz, E.7
Fitzgerald, K.A.8
-
23
-
-
62549122914
-
Innate immunity: Cytoplasmic DNA sensing by the AIM2 inflammasome
-
10.1016/j.cub.2009.02.011. 19321146
-
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome. K Schroder DA Muruve J Tschopp, Curr Biol 2009 19 262 265 10.1016/j.cub.2009.02. 011 19321146
-
(2009)
Curr Biol
, vol.19
, pp. 18262-265
-
-
Schroder, K.1
Muruve, D.A.2
Tschopp, J.3
-
24
-
-
33947497237
-
NALP1 in vitiligo-associated multiple autoimmune disease
-
10.1056/NEJMoa061592. 17377159
-
NALP1 in vitiligo-associated multiple autoimmune disease. Y Jin CM Mailloux K Gowan SL Riccardi G LaBerge DC Bennett PR Fain RA Spritz, N Engl J Med 2007 356 1216 1225 10.1056/NEJMoa061592 17377159
-
(2007)
N Engl J Med
, vol.356
, pp. 1216-1225
-
-
Jin, Y.1
Mailloux, C.M.2
Gowan, K.3
Riccardi, S.L.4
Laberge, G.5
Bennett, D.C.6
Fain, P.R.7
Spritz, R.A.8
-
25
-
-
34250792190
-
Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity
-
10.1038/sj.jid.5700819. 17429439
-
Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity. H Watanabe O Gaide V Petrilli F Martinon E Contassot S Roques JA Kummer J Tschopp LE French, J Invest Dermatol 2007 127 1956 1963 10.1038/sj.jid.5700819 17429439
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1956-1963
-
-
Watanabe, H.1
Gaide, O.2
Petrilli, V.3
Martinon, F.4
Contassot, E.5
Roques, S.6
Kummer, J.A.7
Tschopp, J.8
French, L.E.9
-
26
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
10.1038/nature04516. 16407889
-
Gout-associated uric acid crystals activate the NALP3 inflammasome. F Martinon V Petrilli A Mayor A Tardivel J Tschopp, Nature 2006 440 237 241 10.1038/nature04516 16407889
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
27
-
-
33751338504
-
An intronic variable number of tandem repeat polymorphisms of the cold-induced autoinflammatory syndrome 1 (CIAS1) gene modifies gene expression and is associated with essential hypertension
-
10.1038/sj.ejhg.5201698. 16868559
-
An intronic variable number of tandem repeat polymorphisms of the cold-induced autoinflammatory syndrome 1 (CIAS1) gene modifies gene expression and is associated with essential hypertension. T Omi M Kumada T Kamesaki H Okuda L Munkhtulga Y Yanagisawa N Utsumi T Gotoh A Hata M Soma,, et al. Eur J Hum Genet 2006 14 1295 1305 10.1038/sj.ejhg.5201698 16868559
-
(2006)
Eur J Hum Genet
, vol.14
, pp. 1295-1305
-
-
Omi, T.1
Kumada, M.2
Kamesaki, T.3
Okuda, H.4
Munkhtulga, L.5
Yanagisawa, Y.6
Utsumi, N.7
Gotoh, T.8
Hata, A.9
Soma, M.10
-
28
-
-
34250835251
-
The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes
-
10.1016/j.cub.2007.05.074. 17600714
-
The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. L Feldmeyer M Keller G Niklaus D Hohl S Werner HD Beer, Curr Biol 2007 17 1140 1145 10.1016/j.cub.2007.05.074 17600714
-
(2007)
Curr Biol
, vol.17
, pp. 1140-1145
-
-
Feldmeyer, L.1
Keller, M.2
Niklaus, G.3
Hohl, D.4
Werner, S.5
Beer, H.D.6
-
29
-
-
17644375193
-
Expression and regulation of cryopyrin and related proteins in rheumatoid arthritis synovium
-
10.1136/ard.2004.025577. 15498798
-
Expression and regulation of cryopyrin and related proteins in rheumatoid arthritis synovium. S Rosengren HM Hoffman W Bugbee DL Boyle, Ann Rheum Dis 2005 64 708 714 10.1136/ard.2004.025577 15498798
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 708-714
-
-
Rosengren, S.1
Hoffman, H.M.2
Bugbee, W.3
Boyle, D.L.4
-
30
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
10.1038/ni.1636. 18604209
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. A Halle V Hornung GC Petzold CR Stewart BG Monks T Reinheckel KA Fitzgerald E Latz KJ Moore DT Golenbock, Nat Immunol 2008 9 857 865 10.1038/ni.1636 18604209
-
(2008)
Nat Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
32
-
-
27344448749
-
Familial autoinflammatory diseases: Genetics, pathogenesis and treatment
-
10.1097/bor.0000174210.78449.6b. 16093838
-
Familial autoinflammatory diseases: genetics, pathogenesis and treatment. S Stojanov DL Kastner, Curr Opin Rheumatol 2005 17 586 599 10.1097/bor. 0000174210.78449.6b 16093838
-
(2005)
Curr Opin Rheumatol
, vol.17
, pp. 586-599
-
-
Stojanov, S.1
Kastner, D.L.2
-
33
-
-
16944365196
-
A candidate gene for familial mediterranean fever
-
10.1038/ng0997-25. 9288094
-
A candidate gene for familial mediterranean fever. TFF Consortium, Nat Genet 1997 17 25 31 10.1038/ng0997-25 9288094
-
(1997)
Nat Genet
, vol.17
, pp. 25-31
-
-
Consortium, T.F.F.1
-
34
-
-
0030745449
-
Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial mediterranean fever
-
10.1016/S0092-8674(00)80539-5. 9288758
-
Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial mediterranean fever. TIF Consortium, Cell 1997 90 797 807 10.1016/S0092-8674(00)80539-5 9288758
-
(1997)
Cell
, vol.90
, pp. 797-807
-
-
Consortium, T.I.F.1
-
35
-
-
0344823965
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
10.1073/pnas.2135380100. 14595024
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. NG Shoham M Centola E Mansfield KM Hull G Wood CA Wise DL Kastner, Proc Natl Acad Sci USA 2003 100 13501 13506 10.1073/pnas.2135380100 14595024
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
Centola, M.2
Mansfield, E.3
Hull, K.M.4
Wood, G.5
Wise, C.A.6
Kastner, D.L.7
-
36
-
-
40049108218
-
COPs and POPs: Modulators of Inflammasome Activity
-
18056338
-
COPs and POPs: Modulators of Inflammasome Activity. C Stehlik A Dorfleutner, J Immunol 2007 179 7993 7998 18056338
-
(2007)
J Immunol
, vol.179
, pp. 7993-7998
-
-
Stehlik, C.1
Dorfleutner, A.2
-
37
-
-
64849097220
-
Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain
-
10.4049/jimmunol.0802367. 19234215
-
Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain. NB Bryan A Dorfleutner Y Rojanasakul C Stehlik, J Immunol 2009 182 3173 3182 10.4049/jimmunol.0802367 19234215
-
(2009)
J Immunol
, vol.182
, pp. 3173-3182
-
-
Bryan, N.B.1
Dorfleutner, A.2
Rojanasakul, Y.3
Stehlik, C.4
-
38
-
-
33847730763
-
Cellular PYRIN domain-only protein (cPOP) 2 is a candidate regulator of inflammasome activation
-
10.1128/IAI.01315-06. 17178784
-
Cellular PYRIN domain-only protein (cPOP) 2 is a candidate regulator of inflammasome activation. A Dorfleutner NB Bryan SJ Talbott KN Funya SL Rellick JC Reed X Shi Y Rojanasakul DC Flynn C Stehlik, Infect Immun 2007 75 1484 1492 10.1128/IAI.01315-06 17178784
-
(2007)
Infect Immun
, vol.75
, pp. 1484-1492
-
-
Dorfleutner, A.1
Bryan, N.B.2
Talbott, S.J.3
Funya, K.N.4
Rellick, S.L.5
Reed, J.C.6
Shi, X.7
Rojanasakul, Y.8
Flynn, D.C.9
Stehlik, C.10
-
39
-
-
35548929476
-
A Shope Fibroma virus PYRIN-only protein modulates the host immune response
-
10.1007/s11262-007-0141-9. 17676277
-
A Shope Fibroma virus PYRIN-only protein modulates the host immune response. A Dorfleutner SJ McDonald NB Bryan KN Funya JC Reed X Shi DC Flynn Y Rojanasakul C Stehlik, Virus Genes 2007 35 685 694 10.1007/s11262-007-0141-9 17676277
-
(2007)
Virus Genes
, vol.35
, pp. 685-694
-
-
Dorfleutner, A.1
McDonald, S.J.2
Bryan, N.B.3
Funya, K.N.4
Reed, J.C.5
Shi, X.6
Flynn, D.C.7
Rojanasakul, Y.8
Stehlik, C.9
-
40
-
-
0038682430
-
The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated NF-kB and pro-Caspase 1 regulation
-
10.1042/BJ20030304. 12656673
-
The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated NF-kB and pro-Caspase 1 regulation. C Stehlik M Krajewska K Welsh S Krajewski A Godzik JC Reed, Biochem J 2003 373 101 113 10.1042/BJ20030304 12656673
-
(2003)
Biochem J
, vol.373
, pp. 101-113
-
-
Stehlik, C.1
Krajewska, M.2
Welsh, K.3
Krajewski, S.4
Godzik, A.5
Reed, J.C.6
-
41
-
-
33947219338
-
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions
-
17339483
-
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions. F Bedoya LL Sandler JA Harton, J Immunol 2007 178 3837 3845 17339483
-
(2007)
J Immunol
, vol.178
, pp. 3837-3845
-
-
Bedoya, F.1
Sandler, L.L.2
Harton, J.A.3
-
42
-
-
28844466449
-
A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection
-
10.1016/j.immuni.2005.10.003. 16356857
-
A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection. JB Johnston JW Barrett SH Nazarian M Goodwin D Ricuttio G Wang G McFadden, Immunity 2005 23 587 598 10.1016/j.immuni.2005.10.003 16356857
-
(2005)
Immunity
, vol.23
, pp. 587-598
-
-
Johnston, J.B.1
Barrett, J.W.2
Nazarian, S.H.3
Goodwin, M.4
Ricuttio, D.5
Wang, G.6
McFadden, G.7
-
43
-
-
70350006843
-
A splice variant of ASC regulates IL-1beta release and aggregates differently from intact ASC
-
10.1155/2009/287387. 19759850
-
A splice variant of ASC regulates IL-1beta release and aggregates differently from intact ASC. K Matsushita M Takeoka J Sagara N Itano Y Kurose A Nakamura S Taniguchi, Mediators Inflamm 2009 2009 287387 10.1155/2009/287387 19759850
-
(2009)
Mediators Inflamm
, vol.2009
, pp. 287387
-
-
Matsushita, K.1
Takeoka, M.2
Sagara, J.3
Itano, N.4
Kurose, Y.5
Nakamura, A.6
Taniguchi, S.7
-
44
-
-
0033607768
-
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
-
10.1074/jbc.274.48.33835. 10567338
-
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J Masumoto S Taniguchi K Ayukawa H Sarvotham T Kishino N Niikawa E Hidaka T Katsuyama T Higuchi J Sagara, J Biol Chem 1999 274 33835 33838 10.1074/jbc.274.48.33835 10567338
-
(1999)
J Biol Chem
, vol.274
, pp. 33835-33838
-
-
Masumoto, J.1
Taniguchi, S.2
Ayukawa, K.3
Sarvotham, H.4
Kishino, T.5
Niikawa, N.6
Hidaka, E.7
Katsuyama, T.8
Higuchi, T.9
Sagara, J.10
-
45
-
-
0033709108
-
Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1
-
11103777
-
Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1. BB McConnell PM Vertino, Cancer Res 2000 60 6243 6247 11103777
-
(2000)
Cancer Res
, vol.60
, pp. 6243-6247
-
-
McConnell, B.B.1
Vertino, P.M.2
-
46
-
-
0035914452
-
Interaction between Pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis
-
10.1074/jbc.M104730200. 11498534
-
Interaction between Pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis. N Richards P Schaner A Diaz J Stcukey E Shelden A Wadhwa DL Gumucio, J Biol Chem 2001 276 39320 39329 10.1074/jbc.M104730200 11498534
-
(2001)
J Biol Chem
, vol.276
, pp. 39320-39329
-
-
Richards, N.1
Schaner, P.2
Diaz, A.3
Stcukey, J.4
Shelden, E.5
Wadhwa, A.6
Gumucio, D.L.7
-
47
-
-
0037121940
-
The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways
-
10.1084/jem.20021552. 12486103
-
The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways. C Stehlik L Fiorentino A Dorfleutner JM Bruey EM Ariza J Sagara JC Reed, J Exp Med 2002 196 1605 1615 10.1084/jem.20021552 12486103
-
(2002)
J Exp Med
, vol.196
, pp. 1605-1615
-
-
Stehlik, C.1
Fiorentino, L.2
Dorfleutner, A.3
Bruey, J.M.4
Ariza, E.M.5
Sagara, J.6
Reed, J.C.7
-
48
-
-
0034804347
-
Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC
-
DOI 10.1006/bbrc.2000.4190
-
Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC. J Masumoto S Taniguchi J Sagara, Biochem Biophysical Res Commun 2001 280 652 655 10.1006/bbrc.2000.4190 (Pubitemid 32924480)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.280
, Issue.3
, pp. 652-655
-
-
Masumoto, J.1
Taniguchi, S.2
Sagara, J.3
-
49
-
-
47249144272
-
P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage
-
18490713
-
P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage. P Pelegrin C Barroso-Gutierrez A Surprenant, J Immunol 2008 180 7147 7157 18490713
-
(2008)
J Immunol
, vol.180
, pp. 7147-7157
-
-
Pelegrin, P.1
Barroso-Gutierrez, C.2
Surprenant, A.3
-
50
-
-
51249115622
-
Alternative splicing in the NF-kappaB signaling pathway
-
10.1016/j.gene.2008.07.015. 18718859
-
Alternative splicing in the NF-kappaB signaling pathway. JR Leeman TD Gilmore, Gene 2008 423 97 107 10.1016/j.gene.2008.07.015 18718859
-
(2008)
Gene
, vol.423
, pp. 97-107
-
-
Leeman, J.R.1
Gilmore, T.D.2
-
51
-
-
21244439380
-
Regulation of apoptosis by alternative pre-mRNA splicing
-
10.1016/j.molcel.2005.05.026. 15989960
-
Regulation of apoptosis by alternative pre-mRNA splicing. C Schwerk K Schulze-Osthoff, Mol Cell 2005 19 1 13 10.1016/j.molcel.2005.05.026 15989960
-
(2005)
Mol Cell
, vol.19
, pp. 1-13
-
-
Schwerk, C.1
Schulze-Osthoff, K.2
-
52
-
-
56549101959
-
Alternative isoform regulation in human tissue transcriptomes
-
10.1038/nature07509. 18978772
-
Alternative isoform regulation in human tissue transcriptomes. ET Wang R Sandberg S Luo I Khrebtukova L Zhang C Mayr SF Kingsmore GP Schroth CB Burge, Nature 2008 456 470 476 10.1038/nature07509 18978772
-
(2008)
Nature
, vol.456
, pp. 470-476
-
-
Wang, E.T.1
Sandberg, R.2
Luo, S.3
Khrebtukova, I.4
Zhang, L.5
Mayr, C.6
Kingsmore, S.F.7
Schroth, G.P.8
Burge, C.B.9
-
53
-
-
22544451204
-
A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling
-
10.1128/MCB.25.15.6521-6532.2005. 16024789
-
A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling. N Rao S Nguyen K Ngo WP Fung-Leung, Mol Cell Biol 2005 25 6521 6532 10.1128/MCB.25.15.6521-6532.2005 16024789
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6521-6532
-
-
Rao, N.1
Nguyen, S.2
Ngo, K.3
Fung-Leung, W.P.4
-
54
-
-
3042686382
-
The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory
-
10.1074/jbc.M403068200. 15082713
-
The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory. MP Hardy LA O'Neill, J Biol Chem 2004 279 27699 27708 10.1074/jbc.M403068200 15082713
-
(2004)
J Biol Chem
, vol.279
, pp. 27699-27708
-
-
Hardy, M.P.1
O'Neill, L.A.2
-
55
-
-
0036006290
-
Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88
-
10.1016/S0960-9822(02)00712-1. 11909531
-
Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88. S Janssens K Burns J Tschopp R Beyaert, Curr Biol 2002 12 467 471 10.1016/S0960-9822(02)00712-1 11909531
-
(2002)
Curr Biol
, vol.12
, pp. 467-471
-
-
Janssens, S.1
Burns, K.2
Tschopp, J.3
Beyaert, R.4
-
56
-
-
60949106010
-
RIP2-beta: A novel alternative mRNA splice variant of the receptor interacting protein kinase RIP2
-
10.1016/j.molimm.2008.11.002. 19121870
-
RIP2-beta: a novel alternative mRNA splice variant of the receptor interacting protein kinase RIP2. A Krieg G Le Negrate JC Reed, Mol Immunol 2009 46 1163 1170 10.1016/j.molimm.2008.11.002 19121870
-
(2009)
Mol Immunol
, vol.46
, pp. 1163-1170
-
-
Krieg, A.1
Le Negrate, G.2
Reed, J.C.3
-
57
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
10.4049/jimmunol.0901363. 19570822
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. FG Bauernfeind G Horvath A Stutz ES Alnemri K MacDonald D Speert T Fernandes-Alnemri J Wu BG Monks KA Fitzgerald,, et al. J Immunol 2009 183 787 791 10.4049/jimmunol.0901363 19570822
-
(2009)
J Immunol
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
Wu, J.8
Monks, B.G.9
Fitzgerald, K.A.10
-
58
-
-
70450250064
-
Structure and interdomain dynamics of apoptosis-associated speck-like protein containing a CARD (ASC)
-
10.1074/jbc.M109.024273. 19759015
-
Structure and interdomain dynamics of apoptosis-associated speck-like protein containing a CARD (ASC). E de Alba, J Biol Chem 2009 284 32932 32941 10.1074/jbc.M109.024273 19759015
-
(2009)
J Biol Chem
, vol.284
, pp. 32932-32941
-
-
De Alba, E.1
-
59
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase 1 activation
-
10.1038/sj.cdd.4402194. 17599095
-
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase 1 activation. T Fernandes-Alnemri J Wu JW Yu P Datta B Miller W Jankowski S Rosenberg J Zhang ES Alnemri, Cell Death Differ 2007 14 1590 1604 10.1038/sj.cdd.4402194 17599095
-
(2007)
Cell Death Differ
, vol.14
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
Rosenberg, S.7
Zhang, J.8
Alnemri, E.S.9
-
60
-
-
0032101371
-
Death-effector filaments: Novel cytoplasmic structures that recruit caspases and trigger apoptosis
-
1243-1253. 10.1083/jcb.141.5.1243. 9606215
-
Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis. R Siegel D Martin L Zheng S Ng J Bertin J Cohen M Lenardo, J Cell Biol 1998 141 1243 1253 1243-1253. 10.1083/jcb.141.5.1243 9606215
-
(1998)
J Cell Biol
, vol.141
, pp. 1243-1253
-
-
Siegel, R.1
Martin, D.2
Zheng, L.3
Ng, S.4
Bertin, J.5
Cohen, J.6
Lenardo, M.7
-
61
-
-
0042386425
-
The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
-
10.1016/j.jmb.2003.07.007. 14499617
-
The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition. E Liepinsh R Barbals E Dahl A Sharipo E Staub G Otting, J Mol Biol 2003 332 1155 1163 10.1016/j.jmb.2003.07.007 14499617
-
(2003)
J Mol Biol
, vol.332
, pp. 1155-1163
-
-
Liepinsh, E.1
Barbals, R.2
Dahl, E.3
Sharipo, A.4
Staub, E.5
Otting, G.6
-
62
-
-
47249095449
-
Mapping of POP1-binding site on pyrin domain of ASC
-
10.1074/jbc.M801589200. 18362139
-
Mapping of POP1-binding site on pyrin domain of ASC. T Srimathi SL Robins RL Dubas H Chang H Cheng H Roder YC Park, J Biol Chem 2008 283 15390 15398 10.1074/jbc.M801589200 18362139
-
(2008)
J Biol Chem
, vol.283
, pp. 15390-15398
-
-
Srimathi, T.1
Robins, S.L.2
Dubas, R.L.3
Chang, H.4
Cheng, H.5
Roder, H.6
Park, Y.C.7
-
63
-
-
33644772156
-
A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways
-
10.1073/pnas.0505423103. 16492792
-
A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways. P Rosenstiel K Huse A Till J Hampe S Hellmig C Sina S Billmann O von Kampen GH Waetzig M Platzer,, et al. Proc Natl Acad Sci USA 2006 103 3280 3285 10.1073/pnas.0505423103 16492792
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3280-3285
-
-
Rosenstiel, P.1
Huse, K.2
Till, A.3
Hampe, J.4
Hellmig, S.5
Sina, C.6
Billmann, S.7
Von Kampen, O.8
Waetzig, G.H.9
Platzer, M.10
-
64
-
-
0032914182
-
Alternative splicing and programmed cell death
-
10.1046/j.1525-1373.1999.d01-11.x. 9933500
-
Alternative splicing and programmed cell death. ZH Jiang JY Wu, Proc Soc Exp Biol Med 1999 220 64 72 10.1046/j.1525-1373.1999.d01-11.x 9933500
-
(1999)
Proc Soc Exp Biol Med
, vol.220
, pp. 64-72
-
-
Jiang, Z.H.1
Wu, J.Y.2
|