Structure of the absent in melanoma 2 (AIM2) pyrin domain provides insights into the mechanisms of AIM2 autoinhibition and inflammasome assembly

Journal of Biological Chemistry

Volumn 288, Issue 19, 2013, Pages 13225-13235

  Jin, Tengchuan ^a   Perry, Andrew ^a   Smith, Patrick ^a   Jiang, Jiansheng ^a   Xiao, T Sam ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOINHIBITION; HYDROPHOBIC PATCH; INFLAMMASOME; PYRIN DOMAINS;

BIOCHEMISTRY;

BIOLOGY;

ABSENT IN MELANOMA 2; DNA BINDING PROTEIN; DOUBLE STRANDED DNA; INFLAMMASOME; LYSINE; PHENYLALANINE; UNCLASSIFIED DRUG;

ACIDITY; ALPHA HELIX; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROPHOBICITY; INHIBITION KINETICS; MOLECULAR DOCKING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

AIM2; CRYSTAL STRUCTURE; DEATH DOMAIN; IMMUNOLOGY; INFECTIOUS DISEASES; INNATE IMMUNITY; PYD;

AMINO ACID SEQUENCE; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYTOSKELETAL PROTEINS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INFLAMMASOMES; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; STRUCTURAL HOMOLOGY, PROTEIN; SURFACE PROPERTIES;

EID: 84877692253     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.468033     Document Type: Article

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