Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage

Immunity

Volumn 35, Issue 1, 2011, Pages 34-44

  Ali, Syed Raza ^a   Timmer, Anjuli M ^a,c   Bilgrami, Sameera ^a   Park, Eek Joong ^a   Eckmann, Lars ^b   Nizet, Victor ^a,c   Karin, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATE; ANTHRAX TOXIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CONNEXIN 43; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PROTEIN KINASE; PROTEIN KINASE B; PURINERGIC P2X7 RECEPTOR;

ARTICLE; BACILLUS ANTHRACIS; CELL DEATH; ENZYME ACTIVATION; MACROPHAGE; PRIORITY JOURNAL; PROTECTION; PROTEIN ANALYSIS; PROTEIN EXPRESSION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTHRAX; ANTIGENS, BACTERIAL; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BACILLUS ANTHRACIS; BACTERIAL TOXINS; CELLS, CULTURED; CONNEXIN 43; IMMUNITY, INNATE; INFLAMMASOMES; INTERLEUKIN-1BETA; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MUTATION; ONCOGENE PROTEIN V-AKT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, PURINERGIC P2X7; VIRULENCE;

EID: 79960450059     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2011.04.015     Document Type: Article

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