Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury

Journal of Molecular and Cellular Cardiology

Volumn 51, Issue 2, 2011, Pages 244-251

  Toldo, Stefano ^a   Seropian, Ignacio M ^a   Mezzaroma, Eleonora ^a   Van Tassell, Benjamin W ^a   Salloum, Fadi N ^a   Lewis, Eli C ^b   Voelkel, Norbert ^a   Dinarello, Charles A ^b,c   Abbate, Antonio ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Caspase 1; Cell death; Inflammation; NEW Myocardial infarction; NEW Remodeling

Indexed keywords

ALBUMIN; ALPHA 1 ANTITRYPSIN; INTERLEUKIN 1BETA CONVERTING ENZYME;

ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; CORONARY ARTERY LIGATION; ENZYME ACTIVITY; ENZYME INHIBITION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE HOMOGENATE; TRANSTHORACIC ECHOCARDIOGRAPHY;

ACUTE DISEASE; ALPHA 1-ANTITRYPSIN; ANIMALS; CASPASE 1; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; HUMANS; LEUKOCYTES; MALE; MICE; MICE, INBRED ICR; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; SERINE PROTEINASE INHIBITORS; VENTRICULAR REMODELING;

MUS;

EID: 79959516887     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.05.003     Document Type: Article

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