Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis

Molecular Cell

Volumn 11, Issue 3, 2003, Pages 591-604

  Chae, Jae Jin ^a   Komarow, Hirsh D ^a   Cheng, Jun ^b   Wood, Geryl ^a   Raben, Nina ^a   Liu, P Paul ^b   Kastner, Daniel L ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN WITH A CARD; BACTERIUM LIPOPOLYSACCHARIDE; ENDOTOXIN; ENZYME ACTIVATOR; FAMILIAL MEDITERRANEAN FEVER PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BINDING COMPETITION; CELL STIMULATION; FAMILIAL MEDITERRANEAN FEVER; HOMOZYGOSITY; IN VITRO STUDY; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MALE; MOUSE MUTANT; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; THERMOREGULATION;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0037349294     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(03)00056-X     Document Type: Article

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