Novel role of PKR in inflammasome activation and HMGB1 release

Nature

Volumn 488, Issue 7413, 2012, Pages 670-674

  Lu, Ben ^a,b   Nakamura, Takahisa ^c   Inouye, Karen ^c   Li, Jianhua ^a   Tang, Yiting ^a   Lundbäck, Peter ^d   Valdes Ferrer, Sergio I ^a,b   Olofsson, Peder S ^a   Kalb, Thomas ^a   Roth, Jesse ^a   Zou, Yongrui ^a   Erlandsson Harris, Helena ^d   Yang, Huan ^a   Ting, Jenny P Y ^e   Wang, Haichao ^f   Andersson, Ulf ^d   Antoine, Daniel J ^g   Chavan, Sangeeta S ^a   Hotamisligil, Gökhan S ^c   Tracey, Kevin J ^a,b  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b North Shore LIJ Health System ^*  (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f NORTH SHORE UNIVERSITY HOSPITAL   (United States)

^g UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM; ANTHRAX TOXIN; CRYOPYRIN; HIGH MOBILITY GROUP B1 PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; PROTEIN KINASE R; ROTENONE; URATE;

APOPTOSIS; BACTERIUM; BIOCHEMISTRY; BIOTECHNOLOGY; DISEASE TREATMENT; ENZYME ACTIVITY; GENETIC ANALYSIS; INHIBITION; MOLECULAR ANALYSIS; PROTEIN; TOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVATION; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTION; GENE DELETION; MACROPHAGE; MOUSE; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; SALMONELLA TYPHIMURIUM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIGENS, BACTERIAL; APOPTOSIS REGULATORY PROTEINS; BACTERIAL TOXINS; CALCIUM-BINDING PROTEINS; CARD SIGNALING ADAPTOR PROTEINS; CARRIER PROTEINS; CELL LINE; CELLS, CULTURED; CRYSTALLINS; EIF-2 KINASE; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; HMGB1 PROTEIN; HUMANS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; INTERLEUKIN-6; MACROPHAGES, PERITONEAL; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PERITONITIS; PHOSPHORYLATION; RNA, DOUBLE-STRANDED; ROTENONE; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; TRANSFECTION; URIC ACID;

ESCHERICHIA COLI; SALMONELLA TYPHIMURIUM;

EID: 84865511926     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11290     Document Type: Article

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