Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor

EMBO Journal

Volumn 25, Issue 21, 2006, Pages 5071-5082

  Pelegrin, Pablo ^a   Surprenant, Annmarie ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Hemichannel; Inflammasome; Ion channel; Pro inflammatory cytokines; Purine receptors

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBENOXOLONE; CARRIER PROTEIN; DYE; HEPTANOL; INTERLEUKIN 1; INTERLEUKIN 1BETA CONVERTING ENZYME; MEFLOQUINE; MESSENGER RNA; POTASSIUM; PROTEIN PANNEXIN 1; PURINE P2X7 RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CASPASE 1; CELL LINE; CELL MEMBRANE; CONNEXINS; HUMANS; INTERLEUKIN-1BETA; NERVE TISSUE PROTEINS; RATS; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 33750473352     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601378     Document Type: Article

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