-
1
-
-
0036899079
-
Apoptosomes: engines for caspase activation
-
Adams J.M., and Cory S. Apoptosomes: engines for caspase activation. Curr. Opin. Cell Biol. 14 (2002) 715-720
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 715-720
-
-
Adams, J.M.1
Cory, S.2
-
2
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
Agostini L., Martinon F., Burns K., McDermott M.F., Hawkins P.N., and Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20 (2004) 319-325
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
3
-
-
0034282104
-
Hsp27 negatively regulates cell death by interacting with cytochrome c
-
Bruey J.-M., Ducasse C., Bonniaud P., Ravagnan L., Susin S.A., Diaz-Latoud C., Gurbuxani S., Arrigo A.-P., Kroemer G., Solary E., and Garrido C. Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat. Cell Biol. 2 (2000) 645-652
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 645-652
-
-
Bruey, J.-M.1
Ducasse, C.2
Bonniaud, P.3
Ravagnan, L.4
Susin, S.A.5
Diaz-Latoud, C.6
Gurbuxani, S.7
Arrigo, A.-P.8
Kroemer, G.9
Solary, E.10
Garrido, C.11
-
5
-
-
0035937797
-
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis
-
Chu Z.-L., Pio F., Xie Z., Welsh K., Krajewska M., Krajewski S., Godzik A., and Reed J.C. A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis. J. Biol. Chem. 276 (2001) 9239-9245
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9239-9245
-
-
Chu, Z.-L.1
Pio, F.2
Xie, Z.3
Welsh, K.4
Krajewska, M.5
Krajewski, S.6
Godzik, A.7
Reed, J.C.8
-
6
-
-
0034677173
-
The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential
-
Domen J., Cheshier S.H., and Weissman I.L. The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential. J. Exp. Med. 191 (2000) 253-264
-
(2000)
J. Exp. Med.
, vol.191
, pp. 253-264
-
-
Domen, J.1
Cheshier, S.H.2
Weissman, I.L.3
-
7
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
-
Faustin B., Lartigue L., Bruey J.-M., Luciano F., Sergienko E., Bailly-Maitre B., Hanein D., Rouiller I., and Reed J.C. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. Mol. Cell 25 (2007) 713-724
-
(2007)
Mol. Cell
, vol.25
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.-M.3
Luciano, F.4
Sergienko, E.5
Bailly-Maitre, B.6
Hanein, D.7
Rouiller, I.8
Reed, J.C.9
-
8
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
Franchi L., Amer A., Body-Malapel M., Kanneganti T.D., Ozoren N., Jagirdar R., Inohara N., Vandenabeele P., Bertin J., Coyle A., et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat. Immunol. 7 (2006) 576-582
-
(2006)
Nat. Immunol.
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.D.4
Ozoren, N.5
Jagirdar, R.6
Inohara, N.7
Vandenabeele, P.8
Bertin, J.9
Coyle, A.10
-
9
-
-
0038485614
-
Humanin peptide suppresses apoptosis by interfering with Bax activation
-
Guo B., Zhai D., Cabezas E., Welsh K., Nouraini S., Satterthwait A.C., and Reed J.C. Humanin peptide suppresses apoptosis by interfering with Bax activation. Nature 423 (2003) 456-461
-
(2003)
Nature
, vol.423
, pp. 456-461
-
-
Guo, B.1
Zhai, D.2
Cabezas, E.3
Welsh, K.4
Nouraini, S.5
Satterthwait, A.C.6
Reed, J.C.7
-
10
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N., Ogura Y., Fontalba A., Gutierrez O., Pons F., Crespo J., Fukase K., Inamura S., Kusumoto S., Hashimoto M., et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J. Biol. Chem. 278 (2003) 5509-5512
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
Gutierrez, O.4
Pons, F.5
Crespo, J.6
Fukase, K.7
Inamura, S.8
Kusumoto, S.9
Hashimoto, M.10
-
11
-
-
23044452084
-
NACHT-LRR proteins (NLRs) in bacterial infection and immunity
-
Kufer T.A., Fritz J.H., and Philpott D.J. NACHT-LRR proteins (NLRs) in bacterial infection and immunity. Trends Microbiol. 13 (2005) 381-388
-
(2005)
Trends Microbiol.
, vol.13
, pp. 381-388
-
-
Kufer, T.A.1
Fritz, J.H.2
Philpott, D.J.3
-
12
-
-
2542457495
-
Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases
-
Martinon F., and Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 117 (2004) 561-574
-
(2004)
Cell
, vol.117
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
13
-
-
22444433175
-
NLRs join TLRs as innate sensors of pathogens
-
Martinon F., and Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol. 26 (2005) 447-454
-
(2005)
Trends Immunol.
, vol.26
, pp. 447-454
-
-
Martinon, F.1
Tschopp, J.2
-
14
-
-
0036671894
-
The Inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
-
Martinon F., Burns K., and Tschopp J. The Inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β. Mol. Cell 10 (2002) 417-426
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
15
-
-
7944232105
-
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
-
Martinon F., Agostini L., Meylan E., and Tschopp J. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr. Biol. 14 (2004) 1929-1934
-
(2004)
Curr. Biol.
, vol.14
, pp. 1929-1934
-
-
Martinon, F.1
Agostini, L.2
Meylan, E.3
Tschopp, J.4
-
16
-
-
0031731989
-
Genetics of programmed cell death in C. elegans: past, present and future
-
Metzstein M., Stanfield G., and Horvitz H. Genetics of programmed cell death in C. elegans: past, present and future. Trends Genet. 14 (1998) 410-416
-
(1998)
Trends Genet.
, vol.14
, pp. 410-416
-
-
Metzstein, M.1
Stanfield, G.2
Horvitz, H.3
-
17
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao E.A., Alpuche-Aranda C.M., Dors M., Clark A.E., Bader M.W., Miller S.I., and Aderem A. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat. Immunol. 7 (2006) 569-575
-
(2006)
Nat. Immunol.
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
Aderem, A.7
-
18
-
-
0033857980
-
Pathogen-induced apoptosis of macrophages: a common end for different pathogenic strategies
-
Navarre W.W., and Zychlinsky A. Pathogen-induced apoptosis of macrophages: a common end for different pathogenic strategies. Cell. Microbiol. 2 (2000) 265-273
-
(2000)
Cell. Microbiol.
, vol.2
, pp. 265-273
-
-
Navarre, W.W.1
Zychlinsky, A.2
-
19
-
-
1642633791
-
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
-
Ohtsuka T., Ryu H., Minamishima Y.A., Macip S., Sagara J., Nakayama K.I., Aaronson S.A., and Lee S.W. ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway. Nat. Cell Biol. 6 (2004) 121-128
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 121-128
-
-
Ohtsuka, T.1
Ryu, H.2
Minamishima, Y.A.3
Macip, S.4
Sagara, J.5
Nakayama, K.I.6
Aaronson, S.A.7
Lee, S.W.8
-
20
-
-
0035958867
-
Indentification of Ipaf, a human caspase-1 activating protein related to Apaf-1
-
Poyet J.-L., Srinivasula S.M., Tnani M., Razmara M., Fernandes-Alnemri T., and Alnemri E.S. Indentification of Ipaf, a human caspase-1 activating protein related to Apaf-1. J. Biol. Chem. 276 (2001) 28309-28313
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28309-28313
-
-
Poyet, J.-L.1
Srinivasula, S.M.2
Tnani, M.3
Razmara, M.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
21
-
-
17244368276
-
Structure of the apoptotic protease-activating factor 1 bound to ADP
-
Riedl S.J., Li W., Chao Y., Schwarzenbacher R., and Shi Y. Structure of the apoptotic protease-activating factor 1 bound to ADP. Nature 434 (2005) 926-933
-
(2005)
Nature
, vol.434
, pp. 926-933
-
-
Riedl, S.J.1
Li, W.2
Chao, Y.3
Schwarzenbacher, R.4
Shi, Y.5
-
22
-
-
0344628673
-
Effects of aging on mortality, hypothermia, and cytokine induction in mice with endotoxemia or sepsis
-
Saito H., Sherwood E.R., Varma T.K., and Evers B.M. Effects of aging on mortality, hypothermia, and cytokine induction in mice with endotoxemia or sepsis. Mech. Ageing Dev. 124 (2003) 1047-1058
-
(2003)
Mech. Ageing Dev.
, vol.124
, pp. 1047-1058
-
-
Saito, H.1
Sherwood, E.R.2
Varma, T.K.3
Evers, B.M.4
-
23
-
-
4544341107
-
The PYRIN connection: novel players in innate immunity and inflammation
-
Stehlik C., and Reed J.C. The PYRIN connection: novel players in innate immunity and inflammation. J. Exp. Med. 200 (2004) 551-558
-
(2004)
J. Exp. Med.
, vol.200
, pp. 551-558
-
-
Stehlik, C.1
Reed, J.C.2
-
24
-
-
14944348965
-
The role of BH3-only proteins in the immune system
-
Strasser A. The role of BH3-only proteins in the immune system. Nat. Rev. Immunol. 5 (2005) 189-200
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 189-200
-
-
Strasser, A.1
-
25
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala F.S., Ogura Y., Szczepanik M., Lara-Tejero M., Lichtenberger G.S., Grant E.P., Bertin J., Coyle A.J., Galan J.E., Askenase P.W., and Flavell R.A. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24 (2006) 317-327
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
Bertin, J.7
Coyle, A.J.8
Galan, J.E.9
Askenase, P.W.10
Flavell, R.A.11
-
26
-
-
33344476398
-
CATERPILLERs, pyrin and hereditary immunological disorders
-
Ting J.P., Kastner D.L., and Hoffman H.M. CATERPILLERs, pyrin and hereditary immunological disorders. Nat. Rev. Immunol. 6 (2006) 183-195
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 183-195
-
-
Ting, J.P.1
Kastner, D.L.2
Hoffman, H.M.3
-
28
-
-
26844485563
-
Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans
-
Yan N., Chai J., Lee E.S., Gu L., Liu Q., He J., Wu J.W., Kokel D., Li H., Hao Q., et al. Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature 437 (2005) 831-837
-
(2005)
Nature
, vol.437
, pp. 831-837
-
-
Yan, N.1
Chai, J.2
Lee, E.S.3
Gu, L.4
Liu, Q.5
He, J.6
Wu, J.W.7
Kokel, D.8
Li, H.9
Hao, Q.10
-
29
-
-
0028206341
-
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with bax
-
Yin X.M., Oltvai Z.N., and Korsmeyer S.J. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with bax. Nature 369 (1994) 321-333
-
(1994)
Nature
, vol.369
, pp. 321-333
-
-
Yin, X.M.1
Oltvai, Z.N.2
Korsmeyer, S.J.3
-
30
-
-
33745872296
-
Comparison of chemical inhibitors of anti-apoptotic Bcl-2-family proteins
-
in press
-
Zhai D., Jin C., Satterthwait A.C., and Reed J.C. Comparison of chemical inhibitors of anti-apoptotic Bcl-2-family proteins. Cell Death Differ. (2006) in press
-
(2006)
Cell Death Differ.
-
-
Zhai, D.1
Jin, C.2
Satterthwait, A.C.3
Reed, J.C.4
-
31
-
-
0346103651
-
Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death
-
Zhang W.H., Wang X., Narayanan M., Zhang Y., Huo C., Reed J.C., and Friedlander R.M. Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death. Proc. Natl. Acad. Sci. USA 100 (2003) 16012-16017
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 16012-16017
-
-
Zhang, W.H.1
Wang, X.2
Narayanan, M.3
Zhang, Y.4
Huo, C.5
Reed, J.C.6
Friedlander, R.M.7
-
32
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey R., Dull T., Mandel R.J., Bukovsky A., Quiroz D., Naldini L., and Trono D. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 72 (1998) 9873-9880
-
(1998)
J. Virol.
, vol.72
, pp. 9873-9880
-
-
Zufferey, R.1
Dull, T.2
Mandel, R.J.3
Bukovsky, A.4
Quiroz, D.5
Naldini, L.6
Trono, D.7
|