-
1
-
-
77950362382
-
The inflammasomes
-
Schroder, K., and J. Tschopp. 2010. The inflammasomes. Cell 140: 821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
2
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello, C. A. 2009. Immunological and inflammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 27: 519-550.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
3
-
-
79951578449
-
Inflammasomes: Current understanding and open questions
-
Bauernfeind, F., A. Ablasser, E. Bartok, S. Kim, J. Schmid-Burgk, T. Cavlar, and V. Hornung. 2011. Inflammasomes: current understanding and open questions. Cell. Mol. Life Sci. 68: 765-783.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 765-783
-
-
Bauernfeind, F.1
Ablasser, A.2
Bartok, E.3
Kim, S.4
Schmid-Burgk, J.5
Cavlar, T.6
Hornung, V.7
-
4
-
-
0346350694
-
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties
-
O'Connor, W., Jr., J. A. Harton, X. Zhu, M. W. Linhoff, and J. P. Ting. 2003. Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties. J. Immunol. 171: 6329-6333.
-
(2003)
J. Immunol.
, vol.171
, pp. 6329-6333
-
-
O'Connor Jr., W.1
Harton, J.A.2
Zhu, X.3
Linhoff, M.W.4
Ting, J.P.5
-
5
-
-
79960542894
-
Cutting edge: Reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
Bauernfeind, F., E. Bartok, A. Rieger, L. Franchi, G. Núñez, and V. Hornung. 2011. Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J. Immunol. 187: 613-617.
-
(2011)
J. Immunol.
, vol.187
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Núñez, G.5
Hornung, V.6
-
6
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind, F. G., G. Horvath, A. Stutz, E. S. Alnemri, K. MacDonald, D. Speert, T. Fernandes-Alnemri, J. Wu, B. G. Monks, K. A. Fitzgerald, et al. 2009. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J. Immunol. 183: 787-791.
-
(2009)
J. Immunol.
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
Wu, J.8
Monks, B.G.9
Fitzgerald, K.A.10
-
7
-
-
77749304034
-
Critical functions of priming and lysosomal damage for NLRP3 activation
-
Hornung, V., and E. Latz. 2010. Critical functions of priming and lysosomal damage for NLRP3 activation. Eur. J. Immunol. 40: 620-623.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 620-623
-
-
Hornung, V.1
Latz, E.2
-
8
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel, D. P. 2009. MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
9
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek, D., J. Villén, C. Shin, F. D. Camargo, S. P. Gygi, and D. P. Bartel. 2008. The impact of microRNAs on protein output. Nature 455: 64-71.
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villén, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
10
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo, H., N. T. Ingolia, J. S. Weissman, and D. P. Bartel. 2010. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466: 835-840.
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
11
-
-
79952186298
-
MicroRNAs: The fine-tuners of Toll-like receptor signalling
-
O'Neill, L. A., F. J. Sheedy, and C. E. McCoy. 2011. MicroRNAs: the fine-tuners of Toll-like receptor signalling. Nat. Rev. Immunol. 11: 163-175.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 163-175
-
-
O'Neill, L.A.1
Sheedy, F.J.2
McCoy, C.E.3
-
12
-
-
38549095711
-
Micromanagement of the immune system by microRNAs
-
Lodish, H. F., B. Zhou, G. Liu, and C. Z. Chen. 2008. Micromanagement of the immune system by microRNAs. Nat. Rev. Immunol. 8: 120-130.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 120-130
-
-
Lodish, H.F.1
Zhou, B.2
Liu, G.3
Chen, C.Z.4
-
13
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung, V., F. Bauernfeind, A. Halle, E. O. Samstad, H. Kono, K. L. Rock, K. A. Fitzgerald, and E. Latz. 2008. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 9: 847-856.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
14
-
-
58149252151
-
Stable knockdown of microRNA in vivo by lentiviral vectors
-
Gentner, B., G. Schira, A. Giustacchini, M. Amendola, B. D. Brown, M. Ponzoni, and L. Naldini. 2009. Stable knockdown of microRNA in vivo by lentiviral vectors. Nat. Methods 6: 63-66.
-
(2009)
Nat. Methods
, vol.6
, pp. 63-66
-
-
Gentner, B.1
Schira, G.2
Giustacchini, A.3
Amendola, M.4
Brown, B.D.5
Ponzoni, M.6
Naldini, L.7
-
15
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung, V., A. Ablasser, M. Charrel-Dennis, F. Bauernfeind, G. Horvath, D. R. Caffrey, E. Latz, and K. A. Fitzgerald. 2009. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458: 514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Latz, E.7
Fitzgerald, K.A.8
-
16
-
-
70249110860
-
Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation
-
Franchi, L., T. Eigenbrod, and G. Núñez. 2009. Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation. J. Immunol. 183: 792-796.
-
(2009)
J. Immunol.
, vol.183
, pp. 792-796
-
-
Franchi, L.1
Eigenbrod, T.2
Núñez, G.3
-
17
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala, F. S., Y. Ogura, M. Szczepanik, M. Lara-Tejero, G. S. Lichtenberger, E. P. Grant, J. Bertin, A. J. Coyle, J. E. Galán, P. W. Askenase, and R. A. Flavell. 2006. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24: 317-327.
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
Bertin, J.7
Coyle, A.J.8
Galán, J.E.9
Askenase, P.W.10
Flavell, R.A.11
-
18
-
-
28344438648
-
A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis
-
Fazi, F., A. Rosa, A. Fatica, V. Gelmetti, M. L. De Marchis, C. Nervi, and I. Bozzoni. 2005. A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell 123: 819-831.
-
(2005)
Cell
, vol.123
, pp. 819-831
-
-
Fazi, F.1
Rosa, A.2
Fatica, A.3
Gelmetti, V.4
De Marchis, M.L.5
Nervi, C.6
Bozzoni, I.7
-
19
-
-
34247483919
-
An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling
-
Fukao, T., Y. Fukuda, K. Kiga, J. Sharif, K. Hino, Y. Enomoto, A. Kawamura, K. Nakamura, T. Takeuchi, and M. Tanabe. 2007. An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling. Cell 129: 617-631.
-
(2007)
Cell
, vol.129
, pp. 617-631
-
-
Fukao, T.1
Fukuda, Y.2
Kiga, K.3
Sharif, J.4
Hino, K.5
Enomoto, Y.6
Kawamura, A.7
Nakamura, K.8
Takeuchi, T.9
Tanabe, M.10
-
20
-
-
39849096995
-
Regulation of progenitor cell proliferation and granulocyte function by micro-RNA-223
-
Johnnidis, J. B., M. H. Harris, R. T. Wheeler, S. Stehling-Sun, M. H. Lam, O. Kirak, T. R. Brummelkamp, M. D. Fleming, and F. D. Camargo. 2008. Regulation of progenitor cell proliferation and granulocyte function by micro-RNA-223. Nature 451: 1125-1129.
-
(2008)
Nature
, vol.451
, pp. 1125-1129
-
-
Johnnidis, J.B.1
Harris, M.H.2
Wheeler, R.T.3
Stehling-Sun, S.4
Lam, M.H.5
Kirak, O.6
Brummelkamp, T.R.7
Fleming, M.D.8
Camargo, F.D.9
-
21
-
-
67650736238
-
Horror autoinflammaticus: The molecular pathophysiology of autoinflammatory disease (&z.ast;)
-
Masters, S. L., A. Simon, I. Aksentijevich, and D. L. Kastner. 2009. Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (&z.ast;). Annu. Rev. Immunol. 27: 621-668.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 621-668
-
-
Masters, S.L.1
Simon, A.2
Aksentijevich, I.3
Kastner, D.L.4
-
22
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis, B. P., C. B. Burge, and D. P. Bartel. 2005. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
23
-
-
79960861141
-
GM-CSF signalling boosts dramatically IL-1 production
-
Khameneh, H. J., S. A. Isa, L. Min, F. W. Nih, and C. Ruedl. 2011. GM-CSF signalling boosts dramatically IL-1 production. PLoS ONE 6: e23025.
-
(2011)
PLoS ONE
, vol.6
-
-
Khameneh, H.J.1
Isa, S.A.2
Min, L.3
Nih, F.W.4
Ruedl, C.5
-
24
-
-
84859492693
-
The NLRP3/ASC/Caspase-1 axis regulates IL-1b processing in neutrophils
-
Mankan, A. K., T. Dau, D. Jenne, and V. Hornung. 2012. The NLRP3/ASC/Caspase-1 axis regulates IL-1b processing in neutrophils. Eur. J. Immunol. 42: 710-715.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 710-715
-
-
Mankan, A.K.1
Dau, T.2
Jenne, D.3
Hornung, V.4
-
25
-
-
84862150859
-
A novel regulator of macrophage activation: MiR-223 in obesity-associated adipose tissue inflammation
-
Zhuang, G., C. Meng, X. Guo, P. S. Cheruku, L. Shi, H. Xu, H. Li, G. Wang, A. R. Evans, S. Safe, et al. 2012. A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation. Circulation 125: 2892-2903.
-
(2012)
Circulation
, vol.125
, pp. 2892-2903
-
-
Zhuang, G.1
Meng, C.2
Guo, X.3
Cheruku, P.S.4
Shi, L.5
Xu, H.6
Li, H.7
Wang, G.8
Evans, A.R.9
Safe, S.10
-
26
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon, F., V. Pétrilli, A.Mayor, A. Tardivel, and J. Tschopp. 2006. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440: 237-241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Pétrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
27
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell, P., H. Kono, K. J. Rayner, C. M. Sirois, G. Vladimer, F. G. Bauernfeind, G. S. Abela, L. Franchi, G. Nuñez, M. Schnurr, et al. 2010. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 464: 1357-1361.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nuñez, G.9
Schnurr, M.10
-
28
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1b in type 2 diabetes
-
Masters, S. L., A. Dunne, S. L. Subramanian, R. L. Hull, G. M. Tannahill, F. A. Sharp, C. Becker, L. Franchi, E. Yoshihara, Z. Chen, et al. 2010. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1b in type 2 diabetes. Nat. Immunol. 11: 897-904.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
Becker, C.7
Franchi, L.8
Yoshihara, E.9
Chen, Z.10
-
29
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle, A., V. Hornung, G. C. Petzold, C. R. Stewart, B. G. Monks, T. Reinheckel, K. A. Fitzgerald, E. Latz, K. J. Moore, and D. T. Golenbock. 2008. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat. Immunol. 9: 857-865.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
|