The SPRY domain of pyrin, mutated in familial mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing

Cell Death and Differentiation

Volumn 14, Issue 8, 2007, Pages 1457-1466

  Papin, S ^a   Cuenin, S ^a   Agostini, L ^a   Martinon, F ^a   Werner, S ^b   Beer, H D ^b   Grutter C ^c   Grutter M ^c   Tschopp, J ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN NALP3; PYRIN; SPROUTY PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CINCA SYNDROME; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FAMILIAL COLD AUTOINFLAMMATORY SYNDROME; FAMILIAL MEDITERRANEAN FEVER; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; MUCKLE WELLS SYNDROME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION;

AUTOIMMUNITY; BASE SEQUENCE; CARRIER PROTEINS; CASPASE 1; CELL LINE; CYTOSKELETAL PROTEINS; DNA; FAMILIAL MEDITERRANEAN FEVER; HUMANS; INTERLEUKIN-1; MODELS, BIOLOGICAL; MUTATION; PROTEIN BINDING; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 34547138176     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4402142     Document Type: Article

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