The Medicinal Chemistry of Therapeutic Oligonucleotides

Journal of Medicinal Chemistry

Volumn 59, Issue 21, 2016, Pages 9645-9667

  Brad Wan, W ^a   Seth, Punit P ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; LOCKED NUCLEIC ACID; METHYLPHOSPHONIC ACID; NUCLEIC ACID; NUCLEIC ACID BASE; OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID; PHOSPHORAMIDIC ACID DERIVATIVE; PHOSPHOROTHIOIC ACID; PURINE; PYRIMIDINE DERIVATIVE; SMALL INTERFERING RNA; SUGAR; THYMINE;

DRUG CONJUGATION; DRUG USE; MEDICINAL CHEMISTRY; REVIEW; TOXICOLOGY; CHEMISTRY; CONFORMATION; HUMAN; MOLECULAR MODEL; SYNTHESIS;

CHEMISTRY, PHARMACEUTICAL; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OLIGONUCLEOTIDES;

EID: 84994817779     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.6b00551     Document Type: Review

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