-
1
-
-
29444448260
-
Targeted ablation of plectin isoform 1 uncovers role of cytolinker proteins in leukocyte recruitment
-
Abrahamsberg, C., Fuchs, P., Osmanagic-Myers, S., Fischer, I., Propst, F., Elbe-Burger, A., and Wiche, G. 2005. Targeted ablation of plectin isoform 1 uncovers role of cytolinker proteins in leukocyte recruitment. Proc. Natl. Acad. Sci. 102: 18449-18454.
-
(2005)
Proc. Natl. Acad. Sci
, vol.102
, pp. 18449-18454
-
-
Abrahamsberg, C.1
Fuchs, P.2
Osmanagic-Myers, S.3
Fischer, I.4
Propst, F.5
Elbe-Burger, A.6
Wiche, G.7
-
3
-
-
0032574824
-
Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development
-
Arman, E., Haffner-Krausz, R., Chen, Y., Heath, J.K., and Lonai, P. 1998. Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc. Natl. Acad. Sci. 95: 5082-5087.
-
(1998)
Proc. Natl. Acad. Sci
, vol.95
, pp. 5082-5087
-
-
Arman, E.1
Haffner-Krausz, R.2
Chen, Y.3
Heath, J.K.4
Lonai, P.5
-
4
-
-
32044467372
-
Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice
-
Baraniak, A.P., Chen, J.R., and Garcia-Blanco, M.A. 2006. Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice. Mol. Cell. Biol. 26: 1209-1222.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 1209-1222
-
-
Baraniak, A.P.1
Chen, J.R.2
Garcia-Blanco, M.A.3
-
5
-
-
0032521681
-
Knockout and knockin of the β1 exon D define distinct roles for integrin splice variants in heart function and embryonic development
-
Baudoin, C., Goumans, M.J., Mummery, C., and Sonnenberg, A. 1998. Knockout and knockin of the β1 exon D define distinct roles for integrin splice variants in heart function and embryonic development. Genes & Dev. 12: 1202-1216.
-
(1998)
Genes & Dev
, vol.12
, pp. 1202-1216
-
-
Baudoin, C.1
Goumans, M.J.2
Mummery, C.3
Sonnenberg, A.4
-
6
-
-
0013394889
-
Mechanisms of alternative pre-messenger RNA splicing
-
Black, D.L. 2003. Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 72: 291-336.
-
(2003)
Annu. Rev. Biochem
, vol.72
, pp. 291-336
-
-
Black, D.L.1
-
7
-
-
33745899048
-
Alternative splicing: New insights from global analyses
-
Blencowe, B.J. 2006. Alternative splicing: New insights from global analyses. Cell 126: 37-47.
-
(2006)
Cell
, vol.126
, pp. 37-47
-
-
Blencowe, B.J.1
-
8
-
-
33845270164
-
Imaging the alternative silencing of FGFR2 exon IIIb in vivo
-
Bonano, V.I., Oltean, S., Brazas, R.M., and Garcia-Blanco, M.A. 2006. Imaging the alternative silencing of FGFR2 exon IIIb in vivo. RNA 12: 2073-2079.
-
(2006)
RNA
, vol.12
, pp. 2073-2079
-
-
Bonano, V.I.1
Oltean, S.2
Brazas, R.M.3
Garcia-Blanco, M.A.4
-
9
-
-
0346503889
-
Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice
-
Branda, C.S. and Dymecki, S.M. 2004. Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice. Dev. Cell 6: 7-28.
-
(2004)
Dev. Cell
, vol.6
, pp. 7-28
-
-
Branda, C.S.1
Dymecki, S.M.2
-
10
-
-
0043244855
-
SCNM1, a putative RNA splicing factor that modifies disease severity in mice
-
Buchner, D.A., Trudeau, M., and Meisler, M.H. 2003. SCNM1, a putative RNA splicing factor that modifies disease severity in mice. Science 301: 967-969.
-
(2003)
Science
, vol.301
, pp. 967-969
-
-
Buchner, D.A.1
Trudeau, M.2
Meisler, M.H.3
-
11
-
-
0033137032
-
Alternatively spliced isoforms of nerve- and muscle-derived agrin: Their roles at the neuromuscular junction
-
Burgess, R.W., Nguyen, Q.T., Son, Y.J., Lichtman, J.W., and Sanes, J.R. 1999. Alternatively spliced isoforms of nerve- and muscle-derived agrin: Their roles at the neuromuscular junction. Neuron 23: 33-44.
-
(1999)
Neuron
, vol.23
, pp. 33-44
-
-
Burgess, R.W.1
Nguyen, Q.T.2
Son, Y.J.3
Lichtman, J.W.4
Sanes, J.R.5
-
12
-
-
0029864147
-
+ thymocytes, and B cell maturation
-
+ thymocytes, and B cell maturation. J. Exp. Med. 183: 1707-1718.
-
(1996)
J. Exp. Med
, vol.183
, pp. 1707-1718
-
-
Byth, K.F.1
Conroy, L.A.2
Howlett, S.3
Smith, A.J.4
May, J.5
Alexander, D.R.6
Holmes, N.7
-
13
-
-
0037885015
-
Knock-in of integrin β 1D affects primary but not secondary myogenesis in mice
-
Cachaco, A.S., Chuva de Sousa Lopes, S.M., Kuikman, I., Bajanca, F., Abe, K., Baudoin, C., Sonnenberg, A., Mummery, C.L., and Thorsteinsdottir, S. 2003. Knock-in of integrin β 1D affects primary but not secondary myogenesis in mice. Development 130: 1659-1671.
-
(2003)
Development
, vol.130
, pp. 1659-1671
-
-
Cachaco, A.S.1
Chuva de Sousa Lopes, S.M.2
Kuikman, I.3
Bajanca, F.4
Abe, K.5
Baudoin, C.6
Sonnenberg, A.7
Mummery, C.L.8
Thorsteinsdottir, S.9
-
14
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Eberhardt, C., et al. 1996. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380: 435-439.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Eberhardt, C.10
-
15
-
-
0032925156
-
Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
-
Carmeliet, P., Ng, Y.S., Nuyens, D., Theilmeier, G., Brusselmans, K., Cornelissen, I., Ehler, E., Kakkar, V.V., Stalmans, I., Mattot, V., et al. 1999. Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nat. Med. 5: 495-502.
-
(1999)
Nat. Med
, vol.5
, pp. 495-502
-
-
Carmeliet, P.1
Ng, Y.S.2
Nuyens, D.3
Theilmeier, G.4
Brusselmans, K.5
Cornelissen, I.6
Ehler, E.7
Kakkar, V.V.8
Stalmans, I.9
Mattot, V.10
-
16
-
-
0036207384
-
Listening to silence and understanding nonsense: Exonic mutations that affect splicing
-
Cartegni, L., Chew, S.L., and Krainer, A.R. 2002. Listening to silence and understanding nonsense: Exonic mutations that affect splicing. Nat. Rev. Genet. 3: 285-298.
-
(2002)
Nat. Rev. Genet
, vol.3
, pp. 285-298
-
-
Cartegni, L.1
Chew, S.L.2
Krainer, A.R.3
-
17
-
-
0347419453
-
Alternative splicing of fibronectin: A mouse model demonstrates the identity of in vitro and in vivo systems and the processing autonomy of regulated exons in adult mice
-
Chauhan, A.K., Iaconcig, A., Baralle, F.E., and Muro, A.F. 2004. Alternative splicing of fibronectin: A mouse model demonstrates the identity of in vitro and in vivo systems and the processing autonomy of regulated exons in adult mice. Gene 324: 55-63.
-
(2004)
Gene
, vol.324
, pp. 55-63
-
-
Chauhan, A.K.1
Iaconcig, A.2
Baralle, F.E.3
Muro, A.F.4
-
18
-
-
19344377593
-
Impaired motor coordination in mice lacking the EDA exon of the fibronectin gene
-
Chauhan, A.K., Moretti, F.A., Iaconcig, A., Baralle, F.E., and Muro, A.F. 2005. Impaired motor coordination in mice lacking the EDA exon of the fibronectin gene. Behav. Brain Res. 161: 31-38.
-
(2005)
Behav. Brain Res
, vol.161
, pp. 31-38
-
-
Chauhan, A.K.1
Moretti, F.A.2
Iaconcig, A.3
Baralle, F.E.4
Muro, A.F.5
-
19
-
-
0023647932
-
Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene
-
Crenshaw 3rd, E.B., Russo, A.F., Swanson, L.W., and Rosenfeld, M.G. 1987. Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene. Cell 49: 389-398.
-
(1987)
Cell
, vol.49
, pp. 389-398
-
-
Crenshaw 3rd, E.B.1
Russo, A.F.2
Swanson, L.W.3
Rosenfeld, M.G.4
-
20
-
-
1342333140
-
Integrins in regulation of tissue development and function
-
Danen, E.H. and Sonnenberg, A. 2003. Integrins in regulation of tissue development and function. J. Pathol. 201: 632-641.
-
(2003)
J. Pathol
, vol.201
, pp. 632-641
-
-
Danen, E.H.1
Sonnenberg, A.2
-
21
-
-
0033961133
-
An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis
-
De Moerlooze, L., Spencer-Dene, B., Revest, J., Hajihosseini, M., Rosewell, I., and Dickson, C. 2000. An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development 127: 483-492.
-
(2000)
Development
, vol.127
, pp. 483-492
-
-
De Moerlooze, L.1
Spencer-Dene, B.2
Revest, J.3
Hajihosseini, M.4
Rosewell, I.5
Dickson, C.6
-
22
-
-
34447577370
-
Mice deficient for RNA-binding protein brunol1 show reduction of spermatogenesis but are fertile
-
doi: 10.1002/mrd.20742
-
Dev, A., Nayernia, K., Meins, M., Adham, I., Lacone, F., and Engel, W. 2007. Mice deficient for RNA-binding protein brunol1 show reduction of spermatogenesis but are fertile. Mol. Reprod. Dev. doi: 10.1002/mrd.20742.
-
(2007)
Mol. Reprod. Dev
-
-
Dev, A.1
Nayernia, K.2
Meins, M.3
Adham, I.4
Lacone, F.5
Engel, W.6
-
23
-
-
12144285753
-
Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart
-
Ding, J.H., Xu, X., Yang, D., Chu, P.H., Dalton, N.D., Ye, Z., Yeakley, J.M., Cheng, H., Xiao, R.P., Ross, J., et al. 2004. Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J. 23: 885-896.
-
(2004)
EMBO J
, vol.23
, pp. 885-896
-
-
Ding, J.H.1
Xu, X.2
Yang, D.3
Chu, P.H.4
Dalton, N.D.5
Ye, Z.6
Yeakley, J.M.7
Cheng, H.8
Xiao, R.P.9
Ross, J.10
-
24
-
-
0030730986
-
Integrin α 6A β 1 induces CD81-dependent cell motility without engaging the extracellular matrix migration substrate
-
Domanico, S.Z., Pelletier, A.J., Havran, W.L., and Quaranta, V. 1997. Integrin α 6A β 1 induces CD81-dependent cell motility without engaging the extracellular matrix migration substrate. Mol. Biol. Cell 8: 2253-2265.
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 2253-2265
-
-
Domanico, S.Z.1
Pelletier, A.J.2
Havran, W.L.3
Quaranta, V.4
-
25
-
-
27944504221
-
Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1
-
Duan, Z., Zarebski, A., Montoya-Durango, D., Grimes, H.L., and Horwitz, M. 2005. Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1. Mol. Cell. Biol. 25: 10338-10351.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 10338-10351
-
-
Duan, Z.1
Zarebski, A.2
Montoya-Durango, D.3
Grimes, H.L.4
Horwitz, M.5
-
26
-
-
4344627862
-
Regulated tissue-specific alternative splicing of enhanced green fluorescent protein transgenes conferred by α-tropomyosin regulatory elements in transgenic mice
-
Ellis, P.D., Smith, C.W., and Kemp, P. 2004. Regulated tissue-specific alternative splicing of enhanced green fluorescent protein transgenes conferred by α-tropomyosin regulatory elements in transgenic mice. J. Biol. Chem. 279: 36660-36669.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 36660-36669
-
-
Ellis, P.D.1
Smith, C.W.2
Kemp, P.3
-
27
-
-
0028096639
-
Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing
-
Epstein, J.A., Glaser, T., Cai, J., Jepeal, L., Walton, D.S., and Maas, R.L. 1994. Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing. Genes & Dev. 8: 2022-2034.
-
(1994)
Genes & Dev
, vol.8
, pp. 2022-2034
-
-
Epstein, J.A.1
Glaser, T.2
Cai, J.3
Jepeal, L.4
Walton, D.S.5
Maas, R.L.6
-
28
-
-
0037443035
-
Pre-mRNA splicing and human disease
-
Faustino, N.A. and Cooper, T.A. 2003. Pre-mRNA splicing and human disease. Genes & Dev. 17: 419-437.
-
(2003)
Genes & Dev
, vol.17
, pp. 419-437
-
-
Faustino, N.A.1
Cooper, T.A.2
-
29
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara, N., Carver-Moore, K., Chen, H., Dowd, M., Lu, L., O'Shea, K.S., Powell-Braxton, L., Hillan, K.J., and Moore, M.W. 1996. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380: 439-442.
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
Powell-Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
30
-
-
33645766023
-
Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development
-
Fiolka, K., Hertzano, R., Vassen, L., Zeng, H., Hermesh, O., Avraham, K.B., Duhrsen, U., and Moroy, T. 2006. Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development. EMBO Rep. 7: 326-333.
-
(2006)
EMBO Rep
, vol.7
, pp. 326-333
-
-
Fiolka, K.1
Hertzano, R.2
Vassen, L.3
Zeng, H.4
Hermesh, O.5
Avraham, K.B.6
Duhrsen, U.7
Moroy, T.8
-
31
-
-
0242361316
-
A natural allele of Nxf1 suppresses retrovirus insertional mutations
-
Floyd, J.A., Gold, D.A., Concepcion, D., Poon, T.H., Wang, X., Keithley, E., Chen, D., Ward, E.J., Chinn, S.B., Friedman, R.A., et al. 2003. A natural allele of Nxf1 suppresses retrovirus insertional mutations. Nat. Genet. 35: 221-228.
-
(2003)
Nat. Genet
, vol.35
, pp. 221-228
-
-
Floyd, J.A.1
Gold, D.A.2
Concepcion, D.3
Poon, T.H.4
Wang, X.5
Keithley, E.6
Chen, D.7
Ward, E.J.8
Chinn, S.B.9
Friedman, R.A.10
-
32
-
-
0036790091
-
Mice lacking the EDB segment of fibronectin develop normally but exhibit reduced cell growth and fibronectin matrix assembly in vitro
-
Fukuda, T., Yoshida, N., Kataoka, Y., Manabe, R., Mizuno-Horikawa, Y., Sato, M., Kuriyama, K., Yasui, N., and Sekiguchi, K. 2002. Mice lacking the EDB segment of fibronectin develop normally but exhibit reduced cell growth and fibronectin matrix assembly in vitro. Cancer Res. 62: 5603-5610.
-
(2002)
Cancer Res
, vol.62
, pp. 5603-5610
-
-
Fukuda, T.1
Yoshida, N.2
Kataoka, Y.3
Manabe, R.4
Mizuno-Horikawa, Y.5
Sato, M.6
Kuriyama, K.7
Yasui, N.8
Sekiguchi, K.9
-
33
-
-
0029893117
-
Defective neuromuscular synaptogenesis in agrin-deficient mutant mice
-
Gautam, M., Noakes, P.G., Moscoso, L., Rupp, F., Scheller, R.H., Merlie, J.P., and Sanes, J.R. 1996. Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Cell 85: 525-535.
-
(1996)
Cell
, vol.85
, pp. 525-535
-
-
Gautam, M.1
Noakes, P.G.2
Moscoso, L.3
Rupp, F.4
Scheller, R.H.5
Merlie, J.P.6
Sanes, J.R.7
-
34
-
-
0043133425
-
Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle
-
Gebski, B.L., Mann, C.J., Fletcher, S., and Wilton, S.D. 2003. Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle. Hum. Mol. Genet. 12: 1801-1811.
-
(2003)
Hum. Mol. Genet
, vol.12
, pp. 1801-1811
-
-
Gebski, B.L.1
Mann, C.J.2
Fletcher, S.3
Wilton, S.D.4
-
35
-
-
0027379724
-
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin
-
George, E.L., Georges-Labouesse, E.N., Patel-King, R.S., Rayburn, H., and Hynes, R.O. 1993. Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development 119: 1079-1091.
-
(1993)
Development
, vol.119
, pp. 1079-1091
-
-
George, E.L.1
Georges-Labouesse, E.N.2
Patel-King, R.S.3
Rayburn, H.4
Hynes, R.O.5
-
36
-
-
0032487578
-
Cre-loxP-mediated inactivation of the α6A integrin splice variant in vivo: Evidence for a specific functional role of α6A in lymphocyte migration but not in heart development
-
Gimond, C., Baudoin, C., van der Neut, R., Kramer, D., Calafat, J., and Sonnenberg, A. 1998. Cre-loxP-mediated inactivation of the α6A integrin splice variant in vivo: Evidence for a specific functional role of α6A in lymphocyte migration but not in heart development. J. Cell Biol. 143: 253-266.
-
(1998)
J. Cell Biol
, vol.143
, pp. 253-266
-
-
Gimond, C.1
Baudoin, C.2
van der Neut, R.3
Kramer, D.4
Calafat, J.5
Sonnenberg, A.6
-
37
-
-
0028920569
-
Alternative splicing of the dopamine D2 receptor directs specificity of coupling to G-proteins
-
Guiramand, J., Montmayeur, J.P., Ceraline, J., Bhatia, M., and Borrelli, E. 1995. Alternative splicing of the dopamine D2 receptor directs specificity of coupling to G-proteins. J. Biol. Chem. 270: 7354-7358.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 7354-7358
-
-
Guiramand, J.1
Montmayeur, J.P.2
Ceraline, J.3
Bhatia, M.4
Borrelli, E.5
-
38
-
-
17044369958
-
Specific disruption of smooth muscle caldesmon expression in mice
-
Guo, H. and Wang, C.L. 2005. Specific disruption of smooth muscle caldesmon expression in mice. Biochem. Biophys. Res. Commun. 330: 1132-1137.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.330
, pp. 1132-1137
-
-
Guo, H.1
Wang, C.L.2
-
39
-
-
0035957343
-
A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes
-
Hajihosseini, M.K., Wilson, S., De Moerlooze, L., and Dickson, C. 2001. A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes. Proc. Natl. Acad. Sci. 98: 3855-3860.
-
(2001)
Proc. Natl. Acad. Sci
, vol.98
, pp. 3855-3860
-
-
Hajihosseini, M.K.1
Wilson, S.2
De Moerlooze, L.3
Dickson, C.4
-
40
-
-
0035839099
-
Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation
-
Hammes, A., Guo, J.K., Lutsch, G., Leheste, J.R., Landrock, D., Ziegler, U., Gubler, M.C., and Schedl, A. 2001. Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation. Cell 106: 319-329.
-
(2001)
Cell
, vol.106
, pp. 319-329
-
-
Hammes, A.1
Guo, J.K.2
Lutsch, G.3
Leheste, J.R.4
Landrock, D.5
Ziegler, U.6
Gubler, M.C.7
Schedl, A.8
-
41
-
-
0038815306
-
CD45: A critical regulator of signaling thresholds in immune cells
-
Hermiston, M.L., Xu, Z., and Weiss, A. 2003. CD45: A critical regulator of signaling thresholds in immune cells. Annu. Rev. Immunol. 21: 107-137.
-
(2003)
Annu. Rev. Immunol
, vol.21
, pp. 107-137
-
-
Hermiston, M.L.1
Xu, Z.2
Weiss, A.3
-
42
-
-
33746150385
-
Auxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicing
-
Heyd, F., ten Dam, G., and Moroy, T. 2006. Auxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicing. Nat. Immunol. 7: 859-867.
-
(2006)
Nat. Immunol
, vol.7
, pp. 859-867
-
-
Heyd, F.1
ten Dam, G.2
Moroy, T.3
-
43
-
-
4143120231
-
Muscleblind proteins regulate alternative splicing
-
Ho, T.H., Charlet, B.N., Poulos, M.G., Singh, G., Swanson, M.S., and Cooper, T.A. 2004. Muscleblind proteins regulate alternative splicing. EMBO J. 23: 3103-3112.
-
(2004)
EMBO J
, vol.23
, pp. 3103-3112
-
-
Ho, T.H.1
Charlet, B.N.2
Poulos, M.G.3
Singh, G.4
Swanson, M.S.5
Cooper, T.A.6
-
44
-
-
20444452898
-
Transgenic mice expressing CUG-BP1 reproduce splicing misregulation observed in myotonic dystrophy
-
Ho, T.H., Bundman, D., Armstrong, D.L., and Cooper, T.A. 2005. Transgenic mice expressing CUG-BP1 reproduce splicing misregulation observed in myotonic dystrophy. Hum. Mol. Genet. 14: 1539-1547.
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 1539-1547
-
-
Ho, T.H.1
Bundman, D.2
Armstrong, D.L.3
Cooper, T.A.4
-
45
-
-
7244231429
-
Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells
-
Hock, H., Hamblen, M.J., Rooke, H.M., Schindler, J.W., Saleque, S., Fujiwara, Y., and Orkin, S.H. 2004. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells. Nature 431: 1002-1007.
-
(2004)
Nature
, vol.431
, pp. 1002-1007
-
-
Hock, H.1
Hamblen, M.J.2
Rooke, H.M.3
Schindler, J.W.4
Saleque, S.5
Fujiwara, Y.6
Orkin, S.H.7
-
46
-
-
0033989561
-
Pre-mRNA splicing by the essential Drosophila protein B52: Tissue and target specificity
-
Hoffman, B.E. and Lis, J.T. 2000. Pre-mRNA splicing by the essential Drosophila protein B52: Tissue and target specificity. Mol. Cell. Biol. 20: 181-186.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 181-186
-
-
Hoffman, B.E.1
Lis, J.T.2
-
47
-
-
0032968642
-
Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the γ2 subunit of the γ-aminobutyrate type A receptor
-
Homanics, G.E., Harrison, N.L., Quinlan, J.J., Krasowski, M.D., Rick, C.E., de Blas, A.L., Mehta, A.K., Kist, F., Mihalek, R.M., Aul, J.J., et al. 1999. Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the γ2 subunit of the γ-aminobutyrate type A receptor. Neuropharmacology 38: 253-265.
-
(1999)
Neuropharmacology
, vol.38
, pp. 253-265
-
-
Homanics, G.E.1
Harrison, N.L.2
Quinlan, J.J.3
Krasowski, M.D.4
Rick, C.E.5
de Blas, A.L.6
Mehta, A.K.7
Kist, F.8
Mihalek, R.M.9
Aul, J.J.10
-
48
-
-
0033757702
-
Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability
-
Jensen, K.B., Dredge, B.K., Stefani, G., Zhong, R., Buckanovich, R.J., Okano, H.J., Yang, Y.Y., and Darnell, R.B. 2000. Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability. Neuron 25: 359-371.
-
(2000)
Neuron
, vol.25
, pp. 359-371
-
-
Jensen, K.B.1
Dredge, B.K.2
Stefani, G.3
Zhong, R.4
Buckanovich, R.J.5
Okano, H.J.6
Yang, Y.Y.7
Darnell, R.B.8
-
49
-
-
0033607012
-
Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20
-
Jumaa, H., Wei, G., and Nielsen, P.J. 1999. Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20. Curr. Biol. 9: 899-902.
-
(1999)
Curr. Biol
, vol.9
, pp. 899-902
-
-
Jumaa, H.1
Wei, G.2
Nielsen, P.J.3
-
50
-
-
0027445241
-
The conserved pre-mRNA splicing factor U2AF from Drosophila: Requirement for viability
-
Kanaar, R., Roche, S.E., Beall, E.L., Green, M.R., and Rio, D.C. 1993. The conserved pre-mRNA splicing factor U2AF from Drosophila: Requirement for viability. Science 262: 569-573.
-
(1993)
Science
, vol.262
, pp. 569-573
-
-
Kanaar, R.1
Roche, S.E.2
Beall, E.L.3
Green, M.R.4
Rio, D.C.5
-
51
-
-
0346243804
-
A muscleblind knockout model for myotonic dystrophy
-
Kanadia, R.N., Johnstone, K.A., Mankodi, A., Lungu, C., Thornton, C.A., Esson, D., Timmers, A.M., Hauswirth, W.W., and Swanson, M.S. 2003. A muscleblind knockout model for myotonic dystrophy. Science 302: 1978-1980.
-
(2003)
Science
, vol.302
, pp. 1978-1980
-
-
Kanadia, R.N.1
Johnstone, K.A.2
Mankodi, A.3
Lungu, C.4
Thornton, C.A.5
Esson, D.6
Timmers, A.M.7
Hauswirth, W.W.8
Swanson, M.S.9
-
52
-
-
33746796393
-
Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy
-
Kanadia, R.N., Shin, J., Yuan, Y., Beattie, S.G., Wheeler, T.M., Thornton, C.A., and Swanson, M.S. 2006. Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy. Proc. Natl. Acad. Sci. 103: 11748-11753.
-
(2006)
Proc. Natl. Acad. Sci
, vol.103
, pp. 11748-11753
-
-
Kanadia, R.N.1
Shin, J.2
Yuan, Y.3
Beattie, S.G.4
Wheeler, T.M.5
Thornton, C.A.6
Swanson, M.S.7
-
53
-
-
0036510161
-
Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1
-
Karsunky, H., Zeng, H., Schmidt, T., Zevnik, B., Kluge, R., Schmid, K.W., Duhrsen, U., and Moroy, T. 2002. Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1. Nat. Genet. 30: 295-300.
-
(2002)
Nat. Genet
, vol.30
, pp. 295-300
-
-
Karsunky, H.1
Zeng, H.2
Schmidt, T.3
Zevnik, B.4
Kluge, R.5
Schmid, K.W.6
Duhrsen, U.7
Moroy, T.8
-
54
-
-
27944458349
-
Visualization of alternative splicing in vivo
-
Kemp, P.R., Ellis, P.D., and Smith, C.W. 2005. Visualization of alternative splicing in vivo. Methods 37: 360-367.
-
(2005)
Methods
, vol.37
, pp. 360-367
-
-
Kemp, P.R.1
Ellis, P.D.2
Smith, C.W.3
-
55
-
-
0037388262
-
Specific SR proteindependent splicing substrates identified through genomic SELEX
-
Kim, S., Shi, H., Lee, D.K., and Lis, J.T. 2003. Specific SR proteindependent splicing substrates identified through genomic SELEX. Nucleic Acids Res. 31: 1955-1961.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 1955-1961
-
-
Kim, S.1
Shi, H.2
Lee, D.K.3
Lis, J.T.4
-
56
-
-
0031112267
-
T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45
-
Kozieradzki, I., Kundig, T., Kishihara, K., Ong, C.J., Chiu, D., Wallace, V.A., Kawai, K., Timms, E., Ionescu, J., Ohashi, P., et al. 1997. T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45. J. Immunol. 158: 3130-3139.
-
(1997)
J. Immunol
, vol.158
, pp. 3130-3139
-
-
Kozieradzki, I.1
Kundig, T.2
Kishihara, K.3
Ong, C.J.4
Chiu, D.5
Wallace, V.A.6
Kawai, K.7
Timms, E.8
Ionescu, J.9
Ohashi, P.10
-
57
-
-
0026794668
-
The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences
-
Krawczak, M., Reiss, J., and Cooper, D.N. 1992. The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences. Hum. Genet. 90: 41-54.
-
(1992)
Hum. Genet
, vol.90
, pp. 41-54
-
-
Krawczak, M.1
Reiss, J.2
Cooper, D.N.3
-
58
-
-
0033153348
-
hnRNP complexes: Composition, structure, and function
-
Krecic, A.M. and Swanson, M.S. 1999. hnRNP complexes: Composition, structure, and function. Curr. Opin. Cell Biol. 11: 363-371.
-
(1999)
Curr. Opin. Cell Biol
, vol.11
, pp. 363-371
-
-
Krecic, A.M.1
Swanson, M.S.2
-
59
-
-
20444443019
-
Dynamic balance between activation and repression regulates premRNA alternative splicing during heart development
-
Ladd, A.N., Stenberg, M.G., Swanson, M.S., and Cooper, T.A. 2005a. Dynamic balance between activation and repression regulates premRNA alternative splicing during heart development. Dev. Dyn. 233: 783-793.
-
(2005)
Dev. Dyn
, vol.233
, pp. 783-793
-
-
Ladd, A.N.1
Stenberg, M.G.2
Swanson, M.S.3
Cooper, T.A.4
-
60
-
-
21744448986
-
Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy
-
Ladd, A.N., Taffet, G., Hartley, C., Kearney, D.L., and Cooper, T.A. 2005b. Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy. Mol. Cell. Biol. 25: 6267-6278.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 6267-6278
-
-
Ladd, A.N.1
Taffet, G.2
Hartley, C.3
Kearney, D.L.4
Cooper, T.A.5
-
61
-
-
0034625057
-
Alternative splicing of Wilms' tumor suppressor protein modulates DNA binding activity through isoform-specific DNA-induced conformational changes
-
Laity, J.H., Chung, J., Dyson, H.J., and Wright, P.E. 2000. Alternative splicing of Wilms' tumor suppressor protein modulates DNA binding activity through isoform-specific DNA-induced conformational changes. Biochemistry 39: 5341-5348.
-
(2000)
Biochemistry
, vol.39
, pp. 5341-5348
-
-
Laity, J.H.1
Chung, J.2
Dyson, H.J.3
Wright, P.E.4
-
62
-
-
0036500149
-
Stability of a PKCI-1-related mRNA is controlled by the splicing factor ASF/SF2: A novel function for SR proteins
-
Lemaire, R., Prasad, J., Kashima, T., Gustafson, J., Manley, J.L., and Lafyatis, R. 2002. Stability of a PKCI-1-related mRNA is controlled by the splicing factor ASF/SF2: A novel function for SR proteins. Genes & Dev. 16: 594-607.
-
(2002)
Genes & Dev
, vol.16
, pp. 594-607
-
-
Lemaire, R.1
Prasad, J.2
Kashima, T.3
Gustafson, J.4
Manley, J.L.5
Lafyatis, R.6
-
63
-
-
0037422575
-
Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans
-
Lewis, B.P., Green, R.E., and Brenner, S.E. 2003. Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans. Proc. Natl. Acad. Sci. 100: 189-192.
-
(2003)
Proc. Natl. Acad. Sci
, vol.100
, pp. 189-192
-
-
Lewis, B.P.1
Green, R.E.2
Brenner, S.E.3
-
64
-
-
33745248133
-
Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy
-
Lin, X., Miller, J.W., Mankodi, A., Kanadia, R.N., Yuan, Y., Moxley, R.T., Swanson, M.S., and Thornton, C.A. 2006. Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy. Hum. Mol. Genet. 15: 2087-2097.
-
(2006)
Hum. Mol. Genet
, vol.15
, pp. 2087-2097
-
-
Lin, X.1
Miller, J.W.2
Mankodi, A.3
Kanadia, R.N.4
Yuan, Y.5
Moxley, R.T.6
Swanson, M.S.7
Thornton, C.A.8
-
65
-
-
0037386738
-
Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites
-
Lindgren, N., Usiello, A., Goiny, M., Haycock, J., Erbs, E., Greengard, P., Hokfelt, T., Borrelli, E., and Fisone, G. 2003. Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites. Proc. Natl. Acad. Sci. 100: 4305-4309.
-
(2003)
Proc. Natl. Acad. Sci
, vol.100
, pp. 4305-4309
-
-
Lindgren, N.1
Usiello, A.2
Goiny, M.3
Haycock, J.4
Erbs, E.5
Greengard, P.6
Hokfelt, T.7
Borrelli, E.8
Fisone, G.9
-
66
-
-
0034599949
-
Functional characterization of SR and SR-related genes in Caenorhabditis elegans
-
Longman, D., Johnstone, I.L., and Caceres, J.F. 2000. Functional characterization of SR and SR-related genes in Caenorhabditis elegans. EMBO J. 19: 1625-1637.
-
(2000)
EMBO J
, vol.19
, pp. 1625-1637
-
-
Longman, D.1
Johnstone, I.L.2
Caceres, J.F.3
-
67
-
-
10244239317
-
Consequences of regulated pre-mRNA splicing in the immune system
-
Lynch, K.W. 2004. Consequences of regulated pre-mRNA splicing in the immune system. Nat. Rev. Immunol. 4: 931-940.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 931-940
-
-
Lynch, K.W.1
-
68
-
-
0033986766
-
A model system for activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras
-
Lynch, K.W. and Weiss, A. 2000. A model system for activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras. Mol. Cell. Biol. 20: 70-80.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 70-80
-
-
Lynch, K.W.1
Weiss, A.2
-
69
-
-
0037062982
-
Alternative pre-mRNA splicing and proteome expansion in metazoans
-
Maniatis, T. and Tasic, B. 2002. Alternative pre-mRNA splicing and proteome expansion in metazoans. Nature 418: 236-243.
-
(2002)
Nature
, vol.418
, pp. 236-243
-
-
Maniatis, T.1
Tasic, B.2
-
70
-
-
0034622926
-
Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat
-
Mankodi, A., Logigian, E., Callahan, L., McClain, C., White, R., Henderson, D., Krym, M., and Thornton, C.A. 2000. Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat. Science 289: 1769-1773.
-
(2000)
Science
, vol.289
, pp. 1769-1773
-
-
Mankodi, A.1
Logigian, E.2
Callahan, L.3
McClain, C.4
White, R.5
Henderson, D.6
Krym, M.7
Thornton, C.A.8
-
71
-
-
0034783271
-
Muscleblind localizes to nuclear foci of aberrant RNA in myotonic dystrophy types 1 and 2
-
Mankodi, A., Urbinati, C.R., Yuan, Q.P., Moxley, R.T., Sansone, V., Krym, M., Henderson, D., Schalling, M., Swanson, M.S., and Thornton, C.A. 2001. Muscleblind localizes to nuclear foci of aberrant RNA in myotonic dystrophy types 1 and 2. Hum. Mol. Genet. 10: 2165-2170.
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 2165-2170
-
-
Mankodi, A.1
Urbinati, C.R.2
Yuan, Q.P.3
Moxley, R.T.4
Sansone, V.5
Krym, M.6
Henderson, D.7
Schalling, M.8
Swanson, M.S.9
Thornton, C.A.10
-
72
-
-
0036347525
-
Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy
-
Mankodi, A., Takahashi, M.P., Jiang, H., Beck, C.L., Bowers, W.J., Moxley, R.T., Cannon, S.C., and Thornton, C.A. 2002. Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy. Mol. Cell 10: 35-44.
-
(2002)
Mol. Cell
, vol.10
, pp. 35-44
-
-
Mankodi, A.1
Takahashi, M.P.2
Jiang, H.3
Beck, C.L.4
Bowers, W.J.5
Moxley, R.T.6
Cannon, S.C.7
Thornton, C.A.8
-
73
-
-
18344364099
-
Understanding alternative splicing: Toward a cellular code
-
Matlin, A.J., Clark, F., and Smith, C.W. 2005. Understanding alternative splicing: Toward a cellular code. Nat. Rev. Mol. Cell Biol. 6: 386-398.
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 386-398
-
-
Matlin, A.J.1
Clark, F.2
Smith, C.W.3
-
74
-
-
0034282958
-
Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy
-
Miller, J.W., Urbinati, C.R., Teng-Umnuay, P., Stenberg, M.G., Byrne, B.J., Thornton, C.A., and Swanson, M.S. 2000. Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy. EMBO J. 19: 4439-4448.
-
(2000)
EMBO J
, vol.19
, pp. 4439-4448
-
-
Miller, J.W.1
Urbinati, C.R.2
Teng-Umnuay, P.3
Stenberg, M.G.4
Byrne, B.J.5
Thornton, C.A.6
Swanson, M.S.7
-
75
-
-
33750062258
-
Diversity of human U2AF splicing factors
-
Mollet, I., Barbosa-Morais, N.L., Andrade, J., and Carmo-Fonseca, M. 2006. Diversity of human U2AF splicing factors. FEBS J. 273: 4807-4816.
-
(2006)
FEBS J
, vol.273
, pp. 4807-4816
-
-
Mollet, I.1
Barbosa-Morais, N.L.2
Andrade, J.3
Carmo-Fonseca, M.4
-
76
-
-
0038825157
-
Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan
-
Muro, A.F., Chauhan, A.K., Gajovic, S., Iaconcig, A., Porro, F., Stanta, G., and Baralle, F.E. 2003. Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan. J. Cell Biol. 162: 149-160.
-
(2003)
J. Cell Biol
, vol.162
, pp. 149-160
-
-
Muro, A.F.1
Chauhan, A.K.2
Gajovic, S.3
Iaconcig, A.4
Porro, F.5
Stanta, G.6
Baralle, F.E.7
-
77
-
-
0043092256
-
Either of the CD45RB and CD45RO isoforms are effective in restoring T cell, but not B cell, development and function in CD45-null mice
-
Ogilvy, S., Louis-Dit-Sully, C., Cooper, J., Cassady, R.L., Alexander, D.R., and Holmes, N. 2003. Either of the CD45RB and CD45RO isoforms are effective in restoring T cell, but not B cell, development and function in CD45-null mice. J. Immunol. 171: 1792-1800.
-
(2003)
J. Immunol
, vol.171
, pp. 1792-1800
-
-
Ogilvy, S.1
Louis-Dit-Sully, C.2
Cooper, J.3
Cassady, R.L.4
Alexander, D.R.5
Holmes, N.6
-
78
-
-
33746479738
-
Macula densa control of renin secretion and preglomerular resistance in mice with selective deletion of the B isoform of the Na, K, 2Cl co-transporter
-
Oppermann, M., Mizel, D., Huang, G., Li, C., Deng, C., Theilig, F., Bachmann, S., Briggs, J., Schnermann, J., and Castrop, H. 2006. Macula densa control of renin secretion and preglomerular resistance in mice with selective deletion of the B isoform of the Na, K, 2Cl co-transporter. J. Am. Soc. Nephrol. 17: 2143-2152.
-
(2006)
J. Am. Soc. Nephrol
, vol.17
, pp. 2143-2152
-
-
Oppermann, M.1
Mizel, D.2
Huang, G.3
Li, C.4
Deng, C.5
Theilig, F.6
Bachmann, S.7
Briggs, J.8
Schnermann, J.9
Castrop, H.10
-
79
-
-
33846662014
-
Renal function in mice with targeted disruption of the A isoform of the Na-K-2Cl co-transporter
-
Oppermann, M., Mizel, D., Kim, S.M., Chen, L., Faulhaber-Walter, R., Huang, Y., Li, C., Deng, C., Briggs, J., Schnermann, J., et al. 2007. Renal function in mice with targeted disruption of the A isoform of the Na-K-2Cl co-transporter. J. Am. Soc. Nephrol. 18: 440-448.
-
(2007)
J. Am. Soc. Nephrol
, vol.18
, pp. 440-448
-
-
Oppermann, M.1
Mizel, D.2
Kim, S.M.3
Chen, L.4
Faulhaber-Walter, R.5
Huang, Y.6
Li, C.7
Deng, C.8
Briggs, J.9
Schnermann, J.10
-
80
-
-
0027199056
-
Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)
-
Orr-Urtreger, A., Bedford, M.T., Burakova, T., Arman, E., Zimmer, Y., Yayon, A., Givol, D., and Lonai, P. 1993. Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2). Dev. Biol. 158: 475-486.
-
(1993)
Dev. Biol
, vol.158
, pp. 475-486
-
-
Orr-Urtreger, A.1
Bedford, M.T.2
Burakova, T.3
Arman, E.4
Zimmer, Y.5
Yayon, A.6
Givol, D.7
Lonai, P.8
-
81
-
-
33644858553
-
The Muscleblind family of proteins: An emerging class of regulators of developmentally programmed alternative splicing
-
Pascual, M., Vicente, M., Monferrer, L., and Artero, R. 2006. The Muscleblind family of proteins: An emerging class of regulators of developmentally programmed alternative splicing. Differentiation 74: 65-80.
-
(2006)
Differentiation
, vol.74
, pp. 65-80
-
-
Pascual, M.1
Vicente, M.2
Monferrer, L.3
Artero, R.4
-
82
-
-
0033593328
-
2+-ATPase isoform 2 (SERCA2) gene
-
2+-ATPase isoform 2 (SERCA2) gene. J. Biol. Chem. 274: 2556-2562.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 2556-2562
-
-
Periasamy, M.1
Reed, T.D.2
Liu, L.H.3
Ji, Y.4
Loukianov, E.5
Paul, R.J.6
Nieman, M.L.7
Riddle, T.8
Duffy, J.J.9
Doetschman, T.10
-
83
-
-
0028229714
-
Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung
-
Peters, K., Werner, S., Liao, X., Wert, S., Whitsett, J., and Williams, L. 1994. Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J. 13: 3296-3301.
-
(1994)
EMBO J
, vol.13
, pp. 3296-3301
-
-
Peters, K.1
Werner, S.2
Liao, X.3
Wert, S.4
Whitsett, J.5
Williams, L.6
-
84
-
-
0345099646
-
Arginine/serine repeats are sufficient to constitute a splicing activation domain
-
Philipps, D., Celotto, A.M., Wang, Q.Q., Tarng, R.S., and Graveley, B.R. 2003. Arginine/serine repeats are sufficient to constitute a splicing activation domain. Nucleic Acids Res. 31: 6502-6508.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6502-6508
-
-
Philipps, D.1
Celotto, A.M.2
Wang, Q.Q.3
Tarng, R.S.4
Graveley, B.R.5
-
85
-
-
0027492990
-
U2AF homolog required for splicing in vivo
-
Potashkin, J., Naik, K., and Wentz-Hunter, K. 1993. U2AF homolog required for splicing in vivo. Science 262: 573-575.
-
(1993)
Science
, vol.262
, pp. 573-575
-
-
Potashkin, J.1
Naik, K.2
Wentz-Hunter, K.3
-
86
-
-
0035281514
-
Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4
-
Revest, J.M., Spencer-Dene, B., Kerr, K., De Moerlooze, L., Rosewell, I., and Dickson, C. 2001. Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4. Dev. Biol. 231: 47-62.
-
(2001)
Dev. Biol
, vol.231
, pp. 47-62
-
-
Revest, J.M.1
Spencer-Dene, B.2
Kerr, K.3
De Moerlooze, L.4
Rosewell, I.5
Dickson, C.6
-
87
-
-
0028046121
-
The SR protein B52/SRp55 is essential for Drosophila development
-
Ring, H.Z. and Lis, J.T. 1994. The SR protein B52/SRp55 is essential for Drosophila development. Mol. Cell. Biol. 14: 7499-7506.
-
(1994)
Mol. Cell. Biol
, vol.14
, pp. 7499-7506
-
-
Ring, H.Z.1
Lis, J.T.2
-
88
-
-
19944394558
-
Hypomorphic mutation in hnRNP U results in post-implantation lethality
-
Roshon, M.J. and Ruley, H.E. 2005. Hypomorphic mutation in hnRNP U results in post-implantation lethality. Transgenic Res. 14: 179-192.
-
(2005)
Transgenic Res
, vol.14
, pp. 179-192
-
-
Roshon, M.J.1
Ruley, H.E.2
-
89
-
-
0345276470
-
A conserved signal-responsive sequence mediates activation-induced alternative splicing of CD45
-
Rothrock, C., Cannon, B., Hahm, B., and Lynch, K.W. 2003. A conserved signal-responsive sequence mediates activation-induced alternative splicing of CD45. Mol. Cell 12: 1317-1324.
-
(2003)
Mol. Cell
, vol.12
, pp. 1317-1324
-
-
Rothrock, C.1
Cannon, B.2
Hahm, B.3
Lynch, K.W.4
-
90
-
-
23844471326
-
HnRNP L represses exon splicing via a regulated exonic splicing silencer
-
Rothrock, C.R., House, A.E., and Lynch, K.W. 2005. HnRNP L represses exon splicing via a regulated exonic splicing silencer. EMBO J. 24: 2792-2802.
-
(2005)
EMBO J
, vol.24
, pp. 2792-2802
-
-
Rothrock, C.R.1
House, A.E.2
Lynch, K.W.3
-
91
-
-
0029814786
-
Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects
-
Rudner, D.Z., Kanaar, R., Breger, K.S., and Rio, D.C. 1996. Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects. Proc. Natl. Acad. Sci. 93: 10333-10337.
-
(1996)
Proc. Natl. Acad. Sci
, vol.93
, pp. 10333-10337
-
-
Rudner, D.Z.1
Kanaar, R.2
Breger, K.S.3
Rio, D.C.4
-
92
-
-
0028979458
-
Alpha 6 integrins participate in pro-T cell homing to the thymus
-
Ruiz, P., Wiles, M.V., and Imhof, B.A. 1995. Alpha 6 integrins participate in pro-T cell homing to the thymus. Eur. J. Immunol. 25: 2034-2041.
-
(1995)
Eur. J. Immunol
, vol.25
, pp. 2034-2041
-
-
Ruiz, P.1
Wiles, M.V.2
Imhof, B.A.3
-
93
-
-
0034873099
-
Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy
-
Savkur, R.S., Philips, A.V., and Cooper, T.A. 2001. Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy. Nat. Genet. 29: 40-47.
-
(2001)
Nat. Genet
, vol.29
, pp. 40-47
-
-
Savkur, R.S.1
Philips, A.V.2
Cooper, T.A.3
-
94
-
-
0036903132
-
Systemically delivered antisense oligomers upregulate gene expression in mouse tissues
-
Sazani, P., Gemignani, F., Kang, S.H., Maier, M.A., Manoharan, M., Persmark, M., Bortner, D., and Kole, R. 2002. Systemically delivered antisense oligomers upregulate gene expression in mouse tissues. Nat. Biotechnol. 20: 1228-1233.
-
(2002)
Nat. Biotechnol
, vol.20
, pp. 1228-1233
-
-
Sazani, P.1
Gemignani, F.2
Kang, S.H.3
Maier, M.A.4
Manoharan, M.5
Persmark, M.6
Bortner, D.7
Kole, R.8
-
95
-
-
0033019048
-
Selection and characterization of pre-mRNA splicing enhancers: Identification of novel SR protein-specific enhancer sequences
-
Schaal, T.D. and Maniatis, T. 1999. Selection and characterization of pre-mRNA splicing enhancers: Identification of novel SR protein-specific enhancer sequences. Mol. Cell. Biol. 19: 1705-1719.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 1705-1719
-
-
Schaal, T.D.1
Maniatis, T.2
-
96
-
-
0029075875
-
Cooperative transcriptional activity of Jun and Stat3 β, a short form of Stat3
-
Schaefer, T.S., Sanders, L.K., and Nathans, D. 1995. Cooperative transcriptional activity of Jun and Stat3 β, a short form of Stat3. Proc. Natl. Acad. Sci. 92: 9097-9101.
-
(1995)
Proc. Natl. Acad. Sci
, vol.92
, pp. 9097-9101
-
-
Schaefer, T.S.1
Sanders, L.K.2
Nathans, D.3
-
97
-
-
21244439380
-
Regulation of apoptosis by alternative pre-mRNA splicing
-
Schwerk, C. and Schulze-Osthoff, K. 2005. Regulation of apoptosis by alternative pre-mRNA splicing. Mol. Cell 19: 1-13.
-
(2005)
Mol. Cell
, vol.19
, pp. 1-13
-
-
Schwerk, C.1
Schulze-Osthoff, K.2
-
98
-
-
0036909533
-
Identification of cells deficient in signaling-induced alternative splicing by use of somatic cell genetics
-
Sheives, P. and Lynch, K.W. 2002. Identification of cells deficient in signaling-induced alternative splicing by use of somatic cell genetics. RNA 8: 1473-1481.
-
(2002)
RNA
, vol.8
, pp. 1473-1481
-
-
Sheives, P.1
Lynch, K.W.2
-
100
-
-
0031760295
-
Development of glycinergic synaptic transmission to rat brain stem motoneurons
-
Singer, J.H., Talley, E.M., Bayliss, D.A., and Berger, A.J. 1998. Development of glycinergic synaptic transmission to rat brain stem motoneurons. J. Neurophysiol. 80: 2608-2620.
-
(1998)
J. Neurophysiol
, vol.80
, pp. 2608-2620
-
-
Singer, J.H.1
Talley, E.M.2
Bayliss, D.A.3
Berger, A.J.4
-
101
-
-
0037076371
-
Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform
-
Singh, S., Mishra, R., Arango, N.A., Deng, J.M., Behringer, R.R., and Saunders, G.F. 2002. Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform. Proc. Natl. Acad. Sci. 99: 6812-6815.
-
(2002)
Proc. Natl. Acad. Sci
, vol.99
, pp. 6812-6815
-
-
Singh, S.1
Mishra, R.2
Arango, N.A.3
Deng, J.M.4
Behringer, R.R.5
Saunders, G.F.6
-
102
-
-
33746927884
-
The connection between splicing and cancer
-
Srebrow, A. and Kornblihtt, A.R. 2006. The connection between splicing and cancer. J. Cell Sci. 119: 2635-2641.
-
(2006)
J. Cell Sci
, vol.119
, pp. 2635-2641
-
-
Srebrow, A.1
Kornblihtt, A.R.2
-
103
-
-
0036174063
-
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms
-
Stalmans, I., Ng, Y.S., Rohan, R., Fruttiger, M., Bouche, A., Yuce, A., Fujisawa, H., Hermans, B., Shani, M., Jansen, S., et al. 2002. Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J. Clin. Invest. 109: 327-336.
-
(2002)
J. Clin. Invest
, vol.109
, pp. 327-336
-
-
Stalmans, I.1
Ng, Y.S.2
Rohan, R.3
Fruttiger, M.4
Bouche, A.5
Yuce, A.6
Fujisawa, H.7
Hermans, B.8
Shani, M.9
Jansen, S.10
-
104
-
-
0033152209
-
Determinants of SR protein specificity
-
Tacke, R. and Manley, J.L. 1999. Determinants of SR protein specificity. Curr. Opin. Cell Biol. 11: 358-362.
-
(1999)
Curr. Opin. Cell Biol
, vol.11
, pp. 358-362
-
-
Tacke, R.1
Manley, J.L.2
-
105
-
-
0034625084
-
Uncompensated polyuria in a mouse model of Bartter's syndrome
-
Takahashi, N., Chernavvsky, D.R., Gomez, R.A., Igarashi, P., Gitelman, H.J., and Smithies, O. 2000. Uncompensated polyuria in a mouse model of Bartter's syndrome. Proc. Natl. Acad. Sci. 97: 5434-5439.
-
(2000)
Proc. Natl. Acad. Sci
, vol.97
, pp. 5434-5439
-
-
Takahashi, N.1
Chernavvsky, D.R.2
Gomez, R.A.3
Igarashi, P.4
Gitelman, H.J.5
Smithies, O.6
-
106
-
-
3042708208
-
Deletion of the alternatively spliced fibronectin EIIIA domain in mice reduces atherosclerosis
-
Tan, M.H., Sun, Z., Opitz, S.L., Schmidt, T.E., Peters, J.H., and George, E.L. 2004. Deletion of the alternatively spliced fibronectin EIIIA domain in mice reduces atherosclerosis. Blood 104: 11-18.
-
(2004)
Blood
, vol.104
, pp. 11-18
-
-
Tan, M.H.1
Sun, Z.2
Opitz, S.L.3
Schmidt, T.E.4
Peters, J.H.5
George, E.L.6
-
107
-
-
0033570899
-
CUG repeat binding protein (CUGBP1) interacts with the 5′ region of C/EBPβ mRNA and regulates translation of C/EBPβ isoforms
-
Timchenko, N.A., Welm, A.L., Lu, X., and Timchenko, L.T. 1999. CUG repeat binding protein (CUGBP1) interacts with the 5′ region of C/EBPβ mRNA and regulates translation of C/EBPβ isoforms. Nucleic Acids Res. 27: 4517-4525.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 4517-4525
-
-
Timchenko, N.A.1
Welm, A.L.2
Lu, X.3
Timchenko, L.T.4
-
108
-
-
0035896610
-
RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1
-
Timchenko, N.A., Cai, Z.J., Welm, A.L., Reddy, S., Ashizawa, T., and Timchenko, L.T. 2001. RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1. J. Biol. Chem. 276: 7820-7826.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 7820-7826
-
-
Timchenko, N.A.1
Cai, Z.J.2
Welm, A.L.3
Reddy, S.4
Ashizawa, T.5
Timchenko, L.T.6
-
109
-
-
1842529234
-
Overexpression of CUG triplet repeat-binding protein, CUGBP1, in mice inhibits myogenesis
-
Timchenko, N.A., Patel, R., Iakova, P., Cai, Z.J., Quan, L., and Timchenko, L.T. 2004. Overexpression of CUG triplet repeat-binding protein, CUGBP1, in mice inhibits myogenesis. J. Biol. Chem. 279: 13129-13139.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 13129-13139
-
-
Timchenko, N.A.1
Patel, R.2
Iakova, P.3
Cai, Z.J.4
Quan, L.5
Timchenko, L.T.6
-
110
-
-
34249849472
-
Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110
-
Trede, N.S., Medenbach, J., Damianov, A., Hung, L.H., Weber, G.J., Paw, B.H., Zhou, Y., Hersey, C., Zapata, A., Keefe, M., et al. 2007. Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proc. Natl. Acad. Sci. 104: 6608-6613.
-
(2007)
Proc. Natl. Acad. Sci
, vol.104
, pp. 6608-6613
-
-
Trede, N.S.1
Medenbach, J.2
Damianov, A.3
Hung, L.H.4
Weber, G.J.5
Paw, B.H.6
Zhou, Y.7
Hersey, C.8
Zapata, A.9
Keefe, M.10
-
111
-
-
23044431574
-
Nova regulates brainspecific splicing to shape the synapse
-
Ule, J., Ule, A., Spencer, J., Williams, A., Hu, J.S., Cline, M., Wang, H., Clark, T., Fraser, C., Ruggiu, M., et al. 2005. Nova regulates brainspecific splicing to shape the synapse. Nat. Genet. 37: 844-852.
-
(2005)
Nat. Genet
, vol.37
, pp. 844-852
-
-
Ule, J.1
Ule, A.2
Spencer, J.3
Williams, A.4
Hu, J.S.5
Cline, M.6
Wang, H.7
Clark, T.8
Fraser, C.9
Ruggiu, M.10
-
112
-
-
0034626740
-
Distinct functions of the two isoforms of dopamine D2 receptors
-
Usiello, A., Baik, J.H., Rouge-Pont, F., Picetti, R., Dierich, A., LeMeur, M., Piazza, P.V., and Borrelli, E. 2000. Distinct functions of the two isoforms of dopamine D2 receptors. Nature 408: 199-203.
-
(2000)
Nature
, vol.408
, pp. 199-203
-
-
Usiello, A.1
Baik, J.H.2
Rouge-Pont, F.3
Picetti, R.4
Dierich, A.5
LeMeur, M.6
Piazza, P.V.7
Borrelli, E.8
-
113
-
-
0028984183
-
A novel β 1 integrin isoform produced by alternative splicing: Unique expression in cardiac and skeletal muscle
-
van der Flier, A., Kuikman, I., Baudoin, C., van der Neut, R., and Sonnenberg, A. 1995. A novel β 1 integrin isoform produced by alternative splicing: Unique expression in cardiac and skeletal muscle. FEBS Lett. 369: 340-344.
-
(1995)
FEBS Lett
, vol.369
, pp. 340-344
-
-
van der Flier, A.1
Kuikman, I.2
Baudoin, C.3
van der Neut, R.4
Sonnenberg, A.5
-
114
-
-
7444220147
-
Aberrant and alternative splicing in cancer
-
Venables, J.P. 2004. Aberrant and alternative splicing in cancer. Cancer Res. 64: 7647-7654.
-
(2004)
Cancer Res
, vol.64
, pp. 7647-7654
-
-
Venables, J.P.1
-
115
-
-
0035955750
-
2+-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart
-
2+-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart. Circ. Res. 89: 838-846.
-
(2001)
Circ. Res
, vol.89
, pp. 838-846
-
-
Ver Heyen, M.1
Heymans, S.2
Antoons, G.3
Reed, T.4
Periasamy, M.5
Awede, B.6
Lebacq, J.7
Vangheluwe, P.8
Dewerchin, M.9
Collen, D.10
-
116
-
-
5344222725
-
Modification of the tropomyosin isoform composition of actin filaments in the brain by deletion of an alternatively spliced exon
-
Vrhovski, B., Lemckert, F., and Gunning, P. 2004. Modification of the tropomyosin isoform composition of actin filaments in the brain by deletion of an alternatively spliced exon. Neuropharmacology 47: 684-693.
-
(2004)
Neuropharmacology
, vol.47
, pp. 684-693
-
-
Vrhovski, B.1
Lemckert, F.2
Gunning, P.3
-
117
-
-
0035106072
-
SC35 plays a role in T cell development and alternative splicing of CD45
-
Wang, H.Y., Xu, X., Ding, J.H., Bermingham Jr., J.R., and Fu, X.D. 2001. SC35 plays a role in T cell development and alternative splicing of CD45. Mol. Cell 7: 331-342.
-
(2001)
Mol. Cell
, vol.7
, pp. 331-342
-
-
Wang, H.Y.1
Xu, X.2
Ding, J.H.3
Bermingham Jr., J.R.4
Fu, X.D.5
-
118
-
-
0029859659
-
Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability
-
Wang, J., Takagaki, Y., and Manley, J.L. 1996. Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability. Genes & Dev. 10: 2588-2599.
-
(1996)
Genes & Dev
, vol.10
, pp. 2588-2599
-
-
Wang, J.1
Takagaki, Y.2
Manley, J.L.3
-
119
-
-
0034668907
-
Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions
-
Wang, Y., Xu, R., Sasaoka, T., Tonegawa, S., Kung, M.P., and Sankoorikal, E.B. 2000. Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions. J. Neurosci. 20: 8305-8314.
-
(2000)
J. Neurosci
, vol.20
, pp. 8305-8314
-
-
Wang, Y.1
Xu, R.2
Sasaoka, T.3
Tonegawa, S.4
Kung, M.P.5
Sankoorikal, E.B.6
-
120
-
-
33745289016
-
Induction of dystrophin expression by exon skipping in mdx mice following intramuscular injection of antisense oligonucleotides complexed with PEG-PEI copolymers
-
Williams, J.H., Sirsi, S.R., Latta, D.R., and Lutz, G.J. 2006. Induction of dystrophin expression by exon skipping in mdx mice following intramuscular injection of antisense oligonucleotides complexed with PEG-PEI copolymers. Mol. Ther. 14: 88-96.
-
(2006)
Mol. Ther
, vol.14
, pp. 88-96
-
-
Williams, J.H.1
Sirsi, S.R.2
Latta, D.R.3
Lutz, G.J.4
-
121
-
-
0034068281
-
hnRNP C is required for postimplantation mouse development but is dispensable for cell viability
-
Williamson, D.J., Banik-Maiti, S., DeGregori, J., and Ruley, H.E. 2000. hnRNP C is required for postimplantation mouse development but is dispensable for cell viability. Mol. Cell. Biol. 20: 4094-4105.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 4094-4105
-
-
Williamson, D.J.1
Banik-Maiti, S.2
DeGregori, J.3
Ruley, H.E.4
-
122
-
-
0037036057
-
The effects of dopamine and D2 receptor antagonists on pituitary hormone secretion are intact in mice lacking dopamine D2L receptor
-
Xu, R., Parlow, A.F., and Wang, Y. 2002. The effects of dopamine and D2 receptor antagonists on pituitary hormone secretion are intact in mice lacking dopamine D2L receptor. Brain Res. 939: 95-99.
-
(2002)
Brain Res
, vol.939
, pp. 95-99
-
-
Xu, R.1
Parlow, A.F.2
Wang, Y.3
-
123
-
-
27944434190
-
Conditional knockout mice to study alternative splicing in vivo
-
Xu, X. and Fu, X.D. 2005. Conditional knockout mice to study alternative splicing in vivo. Methods 37: 387-392.
-
(2005)
Methods
, vol.37
, pp. 387-392
-
-
Xu, X.1
Fu, X.D.2
-
124
-
-
19944427655
-
ASF/SF2-regulated CaMKIIδ alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle
-
Xu, X., Yang, D., Ding, J.H., Wang, W., Chu, P.H., Dalton, N.D., Wang, H.Y., Bermingham Jr., J.R., Ye, Z., Liu, F., et al. 2005. ASF/SF2-regulated CaMKIIδ alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell 120: 59-72.
-
(2005)
Cell
, vol.120
, pp. 59-72
-
-
Xu, X.1
Yang, D.2
Ding, J.H.3
Wang, W.4
Chu, P.H.5
Dalton, N.D.6
Wang, H.Y.7
Bermingham Jr., J.R.8
Ye, Z.9
Liu, F.10
-
125
-
-
10944229314
-
Variation in alternative splicing across human tissues
-
Yeo, G., Holste, D., Kreiman, G., and Burge, C.B. 2004. Variation in alternative splicing across human tissues. Genome Biol. 5: R74.
-
(2004)
Genome Biol
, vol.5
-
-
Yeo, G.1
Holste, D.2
Kreiman, G.3
Burge, C.B.4
-
126
-
-
0036008472
-
Specific ablation of Stat3β distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock
-
Yoo, J.Y., Huso, D.L., Nathans, D., and Desiderio, S. 2002. Specific ablation of Stat3β distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock. Cell 108: 331-344.
-
(2002)
Cell
, vol.108
, pp. 331-344
-
-
Yoo, J.Y.1
Huso, D.L.2
Nathans, D.3
Desiderio, S.4
-
127
-
-
8144220648
-
Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells
-
Zeng, H., Yucel, R., Kosan, C., Klein-Hitpass, L., and Moroy, T. 2004. Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells. EMBO J. 23: 4116-4125.
-
(2004)
EMBO J
, vol.23
, pp. 4116-4125
-
-
Zeng, H.1
Yucel, R.2
Kosan, C.3
Klein-Hitpass, L.4
Moroy, T.5
-
128
-
-
0032587919
-
U2AF35 is encoded by an essential gene clustered in an operon with RRM/cyclophilin in Caenorhabditis elegans
-
Zorio, D.A. and Blumenthal, T. 1999. U2AF35 is encoded by an essential gene clustered in an operon with RRM/cyclophilin in Caenorhabditis elegans. RNA 5: 487-494.
-
(1999)
RNA
, vol.5
, pp. 487-494
-
-
Zorio, D.A.1
Blumenthal, T.2
|