Clinical pharmacological properties of mipomersen (Kynamro), a second generation antisense inhibitor of apolipoprotein B

British Journal of Clinical Pharmacology

Volumn 76, Issue 2, 2013, Pages 269-276

  Crooke, Stanley T ^a   Geary, Richard S ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

Antisense inhibitor; Familial hypercholesterolaemia; LDL cholesterol; Mipomersen

Indexed keywords

MIPOMERSEN; PLACEBO;

ARTICLE; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG TOLERABILITY; FLU LIKE SYNDROME; HUMAN; HYPERCHOLESTEROLEMIA; NONHUMAN; OPEN STUDY; PHARMACODYNAMICS; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; SIDE EFFECT; URINARY EXCRETION;

ANTISENSE INHIBITOR; FAMILIAL HYPERCHOLESTEROLAEMIA; LDL-CHOLESTEROL; MIPOMERSEN;

APOLIPOPROTEINS B; BIOLOGICAL AVAILABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; HALF-LIFE; HUMANS; OLIGONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SKIN;

EID: 84880668457     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2012.04469.x     Document Type: Article

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