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ChemBioChem

Volumn 14, Issue 1, 2013, Pages 58-62

Synthesis, Duplex Stabilization and Structural Properties of a Fluorinated Carbocyclic LNA Analogue

(4) Seth, Punit P a Pallan, Pradeep S b Swayze, Eric E a Egli, Martin b

a ISIS PHARMACEUTICALS (United States)

b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

Carbocyclic LNA; Duplex stability; Fluorinated nucleosides; Nucleic acids; X ray crystallography

Indexed keywords

2' FLUORO ARABINO NUCLEIC ACID; 2' FLUORO RNA; ANTISENSE OLIGONUCLEOTIDE; FLUORINATED CARBOXYLIC LOCKED NUCLEIC ACID DERIVATIVE; FLUORINATED CARBOXYLIC LOCKED NUCLEIC ACID PHOSPHORAMIDITE; FLUORINE; HEXITOL NUCLEIC ACID; LOCKED NUCLEIC ACID; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORINATION; PRIORITY JOURNAL; SUBSTITUTION REACTION;

BASE SEQUENCE; CHEMISTRY TECHNIQUES, SYNTHETIC; HALOGENATION; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES;

EID: 84871481281 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201200669 Document Type: Article

Times cited : (20)

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