Structure and nuclease resistance of 2′,4′-constrained 2′-O-methoxyethyl (cMOE) and 2′-O-ethyl (cEt) modified DNAs

Chemical Communications

Volumn 48, Issue 66, 2012, Pages 8195-8197

  Pallan, Pradeep S ^a   Allerson, Charles R ^b   Berdeja, Andres ^b   Seth, Punit P ^b   Swayze, Eric E ^b   Prakash, Thazha P ^b   Egli, Martin ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2' O METHOXYETHYL; ANTISENSE OLIGONUCLEOTIDE; CHEMICAL COMPOUND; NUCLEASE; NUCLEIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DNA MODIFICATION; ENZYME STRUCTURE;

EID: 84864199342     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c2cc32286b     Document Type: Article

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