Structure activity relationships of α-l-LNA modified phosphorothioate gapmer antisense oligonucleotides in animals

Molecular Therapy Nucleic Acids

Volumn 1, Issue 10, 2012, Pages e47-

  Seth, Punit P ^a   Jazayeri, Ali ^a   Yu, Jeff ^a   Allerson, Charles R ^b   Bhat, Balkrishen ^b   Swayze, Eric E ^a  

^a ISIS PHARMACEUTICALS   (United States)

^b REGULUS THERAPEUTICS   (United States)

Author keywords

Gapmer; Hepatotoxicity; Immune stimulation; Oligonucleotides; l LNA

Indexed keywords

EID: 84868347571     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2012.34     Document Type: Article

References (40)

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