Sulfonamide bearing oligonucleotides: Simple synthesis and efficient RNA recognition

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 12, 2012, Pages 3843-3849

  Kumar, Pawan ^a,b   Chandak, Navneet ^a   Nielsen, Poul ^b   Sharma, Pawan K ^a  

^a KURUKSHETRA UNIVERSITY   (India)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Stacking; Click chemistry; CuAAC reaction; Oligonucleotides; RNA targeting; Sonogashira coupling

Indexed keywords

3 AZIDOBENZENESULFONAMIDE; 5 [1 [3 [N [(DIMETHYLEMINO)METHYLIDENE]AMINOSULFONYL]PHENYL] 1,2,3 TRIAZOL 4 YL] 5' (4,4' DIMETHOXYTRITYL) 2' DEOXYURIDINE; 5 [1 [3 [N [(DIMETHYLEMINO)METHYLIDENE]AMINOSULFONYL]PHENYL] 1,2,3 TRIAZOL 4 YL] 5' (4,4' DIMETHOXYTRITYL) 3' O [PARA (2 CYANOETHOXY) N,N' DIISOPROPYLAMINOPHOSPHINYL] 2' DEOXYURIDINE; 5 [3 [N [(DIMETHYLAMINO)METHYLIDENE]AMINOSULFONYL]PHENYL)ETHYNYL 5' (4,4' DIMETHOXYTRITYL] 2' DEOXYURIDINE; 5 [3 [N [(DIMETHYLAMINO)METHYLIDENE]AMINOSULFONYL]PHENYL]ETHYNYL 5' (4,4' DIMETHOXYTRITYL) 3' O [PARA (2 CYANOETHOXY) N,N' DIISOPROPYLAMINOPHOSPHINYL] 2' DEOXYURIDINE; 5 [4 [N [(DIMETHYLAMINO)METHYLIDENE]AMINOSULFONYL]PHENYL]ETHYNYL 5' (4,4' DIMETHOXYTRITYL) 2' DEOXYURIDINE; 5 [4 [N [(DIMETHYLAMINO)METHYLIDENE]AMINOSULFONYL]PHENYL]ETHYNYL 5' (4,4' DIMETHOXYTRITYL) 3' O [PARA (2 CYANOETHOXY) N,N' DIISOPROPYLAMINOPHOSPHINYL] 2' DEOXYURIDINE; N DIMETHYLAMINOMETHYLIDINE 3 AZIDOBENZENESULFONAMIDE; N DIMETHYLAMINOMETHYLIDINE 3 IODOBENZENESULFONAMIDE; N DIMETHYLAMINOMETHYLIDINE 4 IODOBENZENESULFONAMIDE; OLIGONUCLEOTIDE; PHENYLTRIAZOLE DERIVATIVE; SULFANILAMIDE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; CYCLOADDITION; DNA RNA HYBRIDIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR RECOGNITION; SONOGASHIRA REACTION; THERMOSTABILITY;

BASE PAIR MISMATCH; OLIGONUCLEOTIDES; RNA; SULFONAMIDES; TEMPERATURE;

EID: 84861579033     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.04.036     Document Type: Conference Paper

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