Asymmetric RNA duplexes mediate RNA interference in mammalian cells

Nature Biotechnology

Volumn 26, Issue 12, 2008, Pages 1379-1382

  Sun, Xiangao ^a   Rogoff, Harry A ^a   Li, Chiang J ^a,b  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; GENETIC ENGINEERING; MAMMALS; RNA;

ANTI SENSES; BASE PAIRS; BIOMEDICAL RESEARCHES; MAMMALIAN CELLS; MAMMALIAN GENES; NEW CLASSES; RNA DUPLEXES; RNA INTERFERENCES; RNAI TECHNOLOGIES; SCAFFOLD STRUCTURES; SHORT INTERFERING RNAS (SIRNA);

NUCLEIC ACIDS;

MESSENGER RNA; RNA INDUCED SILENCING COMPLEX;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MAMMAL CELL; PRIORITY JOURNAL; RNA INTERFERENCE; RNA STRUCTURE;

BASE PAIRING; GENE SILENCING; HELA CELLS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA-INDUCED SILENCING COMPLEX; TRANSFECTION;

MAMMALIA;

EID: 57449107290     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.1512     Document Type: Article

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