-
1
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros,V. (2004) The functions of animal microRNAs. Nature, 431, 350-355.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
2
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel,D.P. (2004) MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
3
-
-
3042767202
-
MicroRNAs: Small RNAs with a big role in gene regulation
-
He,L. and Hannon,G.J. (2004) MicroRNAs: Small RNAs with a big role in gene regulation. Nature Rev. Genet., 5, 522-531.
-
(2004)
Nature Rev. Genet.
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
4
-
-
28044455435
-
microPrimer: The biogenesis and function of microRNA
-
Du,T. and Zamore,P.D. (2005) microPrimer: The biogenesis and function of microRNA. Development, 132, 4645-4652.
-
(2005)
Development
, vol.132
, pp. 4645-4652
-
-
Du, T.1
Zamore, P.D.2
-
5
-
-
22444437609
-
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
-
Zhao,Y., Samal,E. and Srivastava,D. (2005) Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature, 436, 214-220.
-
(2005)
Nature
, vol.436
, pp. 214-220
-
-
Zhao, Y.1
Samal, E.2
Srivastava, D.3
-
6
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen,C.-Z., Li,L., Lodish,H.F. and Bartel,D.P. (2004) MicroRNAs modulate hematopoietic lineage differentiation. Science, 303, 83-87.
-
(2004)
Science
, vol.303
, pp. 83-87
-
-
Chen, C.-Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
-
7
-
-
4143142117
-
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
-
Calin,G.A., Liu,C.G., Sevignani,C., Ferracin,M., Felli,N., Dumitru,C.D., Shimizu,M., Cimmino,A., Zupo,S., Dono,M. et al. (2004) MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl Acad. Sci. USA, 101, 11755-11760.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 11755-11760
-
-
Calin, G.A.1
Liu, C.G.2
Sevignani, C.3
Ferracin, M.4
Felli, N.5
Dumitru, C.D.6
Shimizu, M.7
Cimmino, A.8
Zupo, S.9
Dono, M.10
-
8
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin,G.A., Sevignani,C., Dumitru,C.D., Hyslop,T., Noch,E., Yendamuri,S., Shimizu,M., Rattan,S., Bullrich,F., Negrini,M. et al. (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl Acad. Sci. USA, 101, 2999-3004.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
Yendamuri, S.6
Shimizu, M.7
Rattan, S.8
Bullrich, F.9
Negrini, M.10
-
9
-
-
0345818258
-
MicroRNAs and cancer
-
McManus,M.T. (2003) MicroRNAs and cancer. Semin. Cancer Biol., 13, 253-258.
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 253-258
-
-
McManus, M.T.1
-
10
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu,J., Getz,G., Miska,E.A., Alvarez-Saavedra,E., Lamb,J., Peck,D., Sweet-Cordero,A., Ebert,B.L., Mak,R.H., Ferrando,A.A. et al. (2005) MicroRNA expression profiles classify human cancers. Nature, 435, 834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
-
12
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia,S., Calin,G.A., Liu,C.G., Ambs,S., Cimmino,A., Petrocca,F., Visone,R., Iorio,M., Roldo,C., Ferracin,M. et al. (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl Acad. Sci. USA, 103, 2257-2261.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
Petrocca, F.6
Visone, R.7
Iorio, M.8
Roldo, C.9
Ferracin, M.10
-
13
-
-
10344243662
-
MicroRNA-143 regulates adipocyte differentiation
-
Esau,C., Kang,X., Peralta,E., Hanson,E., Marcusson,E.G., Ravichandran,L.V., Sun,Y., Koo,S., Perera,R.J., Jain,R. et al. (2004) MicroRNA-143 regulates adipocyte differentiation. J. Biol. Chem., 279, 52361-52365.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 52361-52365
-
-
Esau, C.1
Kang, X.2
Peralta, E.3
Hanson, E.4
Marcusson, E.G.5
Ravichandran, L.V.6
Sun, Y.7
Koo, S.8
Perera, R.J.9
Jain, R.10
-
14
-
-
9144270691
-
A pancreatic islet-specific microRNA regulates insulin secretion
-
Poy,M.N., Eliasson,L., Krutzfeldt,J., Kuwajima,S., Ma,X., MacDonald,P.E., Pfeffer,S., Tuschl,T., Rajewsky,N., Rorsman,P. et al. (2004) A pancreatic islet-specific microRNA regulates insulin secretion. Nature, 432, 226-230.
-
(2004)
Nature
, vol.432
, pp. 226-230
-
-
Poy, M.N.1
Eliasson, L.2
Krutzfeldt, J.3
Kuwajima, S.4
Ma, X.5
MacDonald, P.E.6
Pfeffer, S.7
Tuschl, T.8
Rajewsky, N.9
Rorsman, P.10
-
15
-
-
28444469246
-
Silencing of microRNAs in vivo with 'antagomirs'
-
Krutzfeldt,J., Rajewsky,N., Braich,R., Rajeev,K.G., Tuschl,T., Manoharan,M. and Stoffel,M. (2005) Silencing of microRNAs in vivo with 'antagomirs'. Nature, 438, 685-689.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
Stoffel, M.7
-
16
-
-
33645075443
-
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
-
Esau,C., Davis,S., Murray,S.F., Yu,X.X., Pandey,S.K., Pear,M., Watts,L., Booten,S.L., Graham,M., McKay,R. et al. (2006) miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab., 3, 87-98.
-
(2006)
Cell Metab.
, vol.3
, pp. 87-98
-
-
Esau, C.1
Davis, S.2
Murray, S.F.3
Yu, X.X.4
Pandey, S.K.5
Pear, M.6
Watts, L.7
Booten, S.L.8
Graham, M.9
McKay, R.10
-
17
-
-
17644363376
-
A cellular microRNA mediates antiviral defense in human cells
-
Lecellier,C.H., Dunoyer,P., Arar,K., Lehmann-Che,J., Eyquem,S., Himber,C., Saib,A. and Voinnet,O. (2005) A cellular microRNA mediates antiviral defense in human cells. Science, 308, 557-560.
-
(2005)
Science
, vol.308
, pp. 557-560
-
-
Lecellier, C.H.1
Dunoyer, P.2
Arar, K.3
Lehmann-Che, J.4
Eyquem, S.5
Himber, C.6
Saib, A.7
Voinnet, O.8
-
18
-
-
24644483623
-
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
-
Jopling,C.L., Yi,M., Lancaster,A.M., Lemon,S.M. and Sarnow,P. (2005) Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science, 309, 1577-1581.
-
(2005)
Science
, vol.309
, pp. 1577-1581
-
-
Jopling, C.L.1
Yi, M.2
Lancaster, A.M.3
Lemon, S.M.4
Sarnow, P.5
-
19
-
-
33644750115
-
miRBase: MicroRNA sequences, targets and gene nomenclature
-
Griffiths-Jones,S., Grocock,R.J., van Dongen,S., Bateman,A. and Enright,A.J. (2006) miRBase: MicroRNA sequences, targets and gene nomenclature. Nucleic Acids Res., 34, D140-D144.
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.J.2
van Dongen, S.3
Bateman, A.4
Enright, A.J.5
-
20
-
-
33644878178
-
Argonaute - A database for gene regulation by mammalian microRNAs
-
Shahi,P., Loukianiouk,S., Bohne-Lang,A., Kenzelmann,M., Kuffer,S., Maertens,S., Eils,R., Grone,H.J., Gretz,N. and Brors,B. (2006) Argonaute - a database for gene regulation by mammalian microRNAs. Nucleic Acids Res., 34, D115-D118.
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Shahi, P.1
Loukianiouk, S.2
Bohne-Lang, A.3
Kenzelmann, M.4
Kuffer, S.5
Maertens, S.6
Eils, R.7
Grone, H.J.8
Gretz, N.9
Brors, B.10
-
21
-
-
0033485278
-
Antisense oligonucleotides: A systematic high-throughput approach to target validation and gene function determination
-
Taylor,M.F., Wiederholt,K. and Sverdrup,F. (1999) Antisense oligonucleotides: A systematic high-throughput approach to target validation and gene function determination. Drug. Discov. Today, 4, 562-567.
-
(1999)
Drug. Discov. Today
, vol.4
, pp. 562-567
-
-
Taylor, M.F.1
Wiederholt, K.2
Sverdrup, F.3
-
22
-
-
0035709416
-
Functional genomics and target validation approaches using antisense oligonucleotide technology
-
Dean,N.M. (2001) Functional genomics and target validation approaches using antisense oligonucleotide technology. Curr. Opin. Biotechnol., 12, 622-625.
-
(2001)
Curr. Opin. Biotechnol.
, vol.12
, pp. 622-625
-
-
Dean, N.M.1
-
23
-
-
8844232706
-
Functional genomics to new drug targets
-
Kramer,R. and Cohen,D. (2004) Functional genomics to new drug targets. Nature Rev. Drug Discov., 3, 965-972.
-
(2004)
Nature Rev. Drug Discov.
, vol.3
, pp. 965-972
-
-
Kramer, R.1
Cohen, D.2
-
24
-
-
0033039523
-
Antisense oligonucleotides for target validation in the CNS
-
Ho,S.P. and Hartig,P.R. (1999) Antisense oligonucleotides for target validation in the CNS. Curr. Opin. Mol. Ther., 1, 336-343.
-
(1999)
Curr. Opin. Mol. Ther.
, vol.1
, pp. 336-343
-
-
Ho, S.P.1
Hartig, P.R.2
-
25
-
-
33644517511
-
Use of a chemically modified antisense oligonucleotide library to identify and validate Eg5 (kinesin-like 1) as a target for antineoplastic drug development
-
Koller,E., Propp,S., Zhang,H., Zhao,C., Xiao,X., Chang,M., Hirsch,S.A., Shepard,P.J., Koo,S., Murphy,C. et al. (2006) Use of a chemically modified antisense oligonucleotide library to identify and validate Eg5 (kinesin-like 1) as a target for antineoplastic drug development. Cancer Res., 66, 2059-2066.
-
(2006)
Cancer Res.
, vol.66
, pp. 2059-2066
-
-
Koller, E.1
Propp, S.2
Zhang, H.3
Zhao, C.4
Xiao, X.5
Chang, M.6
Hirsch, S.A.7
Shepard, P.J.8
Koo, S.9
Murphy, C.10
-
26
-
-
0141750434
-
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
-
Aza-Blanc,P., Cooper,C.L., Wagner,K., Batalov,S., Deveraux,Q.L. and Cooke,M.P. (2003) Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Mol. Cell, 12, 627-637.
-
(2003)
Mol. Cell
, vol.12
, pp. 627-637
-
-
Aza-Blanc, P.1
Cooper, C.L.2
Wagner, K.3
Batalov, S.4
Deveraux, Q.L.5
Cooke, M.P.6
-
27
-
-
12144289681
-
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
-
Berns,K., Hijmans,E.M., Mullenders,J., Brummelkamp,T.R., Velds,A., Heimerikx,M., Kerkhoven,R.M., Madiredjo,M., Nijkamp, W., Weigelt,B. et al. (2004) A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature, 428, 431-437.
-
(2004)
Nature
, vol.428
, pp. 431-437
-
-
Berns, K.1
Hijmans, E.M.2
Mullenders, J.3
Brummelkamp, T.R.4
Velds, A.5
Heimerikx, M.6
Kerkhoven, R.M.7
Madiredjo, M.8
Nijkamp, W.9
Weigelt, B.10
-
28
-
-
0347089019
-
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells
-
Zheng,L., Liu,J., Batalov,S., Zhou,D., Orth,A., Ding,S. and Schultz,P.G. (2004) An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proc. Natl Acad. Sci. USA, 101, 135-140.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 135-140
-
-
Zheng, L.1
Liu, J.2
Batalov, S.3
Zhou, D.4
Orth, A.5
Ding, S.6
Schultz, P.G.7
-
29
-
-
21344457432
-
RNA interference: From gene silencing to gene-specific therapeutics
-
Leung,R.K. and Whittaker,P.A. (2005) RNA interference: From gene silencing to gene-specific therapeutics. Pharmacol. Ther., 107, 222-239.
-
(2005)
Pharmacol. Ther.
, vol.107
, pp. 222-239
-
-
Leung, R.K.1
Whittaker, P.A.2
-
30
-
-
12544254978
-
Antisense and RNA interference approaches to target validation in pain research
-
Kurreck,J. (2004) Antisense and RNA interference approaches to target validation in pain research. Curr. Opin. Drug Discov. Devel., 7, 179-187.
-
(2004)
Curr. Opin. Drug Discov. Devel.
, vol.7
, pp. 179-187
-
-
Kurreck, J.1
-
31
-
-
0033780376
-
Effective targeted gene 'knockdown' in zebrafish
-
Nasevicius,A. and Ekker,S.C. (2000) Effective targeted gene 'knockdown' in zebrafish. Nature Genet., 26, 216-220.
-
(2000)
Nature Genet.
, vol.26
, pp. 216-220
-
-
Nasevicius, A.1
Ekker, S.C.2
-
32
-
-
0034883854
-
Antitumor activity of antisense clusterin oligonucleotides is improved in vitro and in vivo by incorporation of 2′-O-(2-methoxy)ethyl chemistry
-
Zellweger,T., Miyake,H., Cooper,S., Chi,K., Conklin,B.S., Monia,B.P. and Gleave,M.E. (2001) Antitumor activity of antisense clusterin oligonucleotides is improved in vitro and in vivo by incorporation of 2′-O-(2-methoxy)ethyl chemistry. J. Pharmacol. Exp. Ther., 298, 934-940.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 934-940
-
-
Zellweger, T.1
Miyake, H.2
Cooper, S.3
Chi, K.4
Conklin, B.S.5
Monia, B.P.6
Gleave, M.E.7
-
33
-
-
20044384728
-
Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism
-
Watts,L.M., Manchem,V.P., Leedom,T.A., Rivard,A.L., McKay,R.A., Bao,D., Neroladakis,T., Monia,B.P., Bodenmiller,D.M., Cao,J.X. et al. (2005) Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism. Diabetes, 54, 1846-1853.
-
(2005)
Diabetes
, vol.54
, pp. 1846-1853
-
-
Watts, L.M.1
Manchem, V.P.2
Leedom, T.A.3
Rivard, A.L.4
McKay, R.A.5
Bao, D.6
Neroladakis, T.7
Monia, B.P.8
Bodenmiller, D.M.9
Cao, J.X.10
-
34
-
-
23044450772
-
Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice
-
Yu,X.X., Murray,S.F., Pandey,S.K., Booten,S.L., Bao,D., Song,X.Z., Kelly,S., Chen,S., McKay,R., Monia,B.P. et al. (2005) Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice. Hepatology, 42, 362-371.
-
(2005)
Hepatology
, vol.42
, pp. 362-371
-
-
Yu, X.X.1
Murray, S.F.2
Pandey, S.K.3
Booten, S.L.4
Bao, D.5
Song, X.Z.6
Kelly, S.7
Chen, S.8
McKay, R.9
Monia, B.P.10
-
35
-
-
33745599493
-
GTI-2501, an antisense agent targeting R1, the large subunit of human ribonucleotide reductase, shows potent anti-tumor activity against a variety of tumors
-
Lee,Y., Vassilakos,A., Feng,N., Jin,H., Wang,M., Xiong,K., Wright,J. and Young,A. (2006) GTI-2501, an antisense agent targeting R1, the large subunit of human ribonucleotide reductase, shows potent anti-tumor activity against a variety of tumors. Int. J. Oncol., 28, 469-478.
-
(2006)
Int. J. Oncol.
, vol.28
, pp. 469-478
-
-
Lee, Y.1
Vassilakos, A.2
Feng, N.3
Jin, H.4
Wang, M.5
Xiong, K.6
Wright, J.7
Young, A.8
-
36
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek,J., Akinc,A., Bramlage,B., Charisse,K., Constien,R., Donoghue,M., Elbashir,S., Geick,A., Hadwiger,P., Harborth,J. et al. (2004) Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature, 432, 173-178.
-
(2004)
Nature
, vol.432
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
Charisse, K.4
Constien, R.5
Donoghue, M.6
Elbashir, S.7
Geick, A.8
Hadwiger, P.9
Harborth, J.10
-
37
-
-
0034721317
-
Inhibition of C-raf expression by antisense oligonucleotides extends heart allograft survival in rats
-
Stepkowski,S.M., Qu,X., Wang,M.E., Tian,L., Chen,W., Wancewicz,E.V., Johnston,J.F., Bennett,C.F. and Monia,B.P. (2000) Inhibition of C-raf expression by antisense oligonucleotides extends heart allograft survival in rats. Transplantation, 70, 656-661.
-
(2000)
Transplantation
, vol.70
, pp. 656-661
-
-
Stepkowski, S.M.1
Qu, X.2
Wang, M.E.3
Tian, L.4
Chen, W.5
Wancewicz, E.V.6
Johnston, J.F.7
Bennett, C.F.8
Monia, B.P.9
-
38
-
-
24744470522
-
A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2′-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer
-
Chi,K.N., Eisenhauer,E., Fazli,L., Jones,E.C., Goldenberg,S.L., Powers,J., Tu,D. and Gleave,M.E. (2005) A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2′-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer. J. Natl. Cancer Inst., 97, 1287-1296.
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 1287-1296
-
-
Chi, K.N.1
Eisenhauer, E.2
Fazli, L.3
Jones, E.C.4
Goldenberg, S.L.5
Powers, J.6
Tu, D.7
Gleave, M.E.8
-
39
-
-
1642430704
-
Antisense oligonucleotide-based therapeutics for cancer
-
Dean,N.M. and Bennett,C.F. (2003) Antisense oligonucleotide-based therapeutics for cancer. Oncogene, 22, 9087-9096.
-
(2003)
Oncogene
, vol.22
, pp. 9087-9096
-
-
Dean, N.M.1
Bennett, C.F.2
-
40
-
-
7944230575
-
Oligonucleotide therapeutics: 25 years agrowing
-
Goodchild,J. (2004) Oligonucleotide therapeutics: 25 years agrowing. Curr. Opin. Mol. Ther., 6, 120-128.
-
(2004)
Curr. Opin. Mol. Ther.
, vol.6
, pp. 120-128
-
-
Goodchild, J.1
-
41
-
-
3242719541
-
Antisense strategies
-
Crooke,S.T. (2004) Antisense strategies. Curr. Mol. Med., 4, 465-487.
-
(2004)
Curr. Mol. Med.
, vol.4
, pp. 465-487
-
-
Crooke, S.T.1
-
42
-
-
5444256072
-
A functionally improved locked nucleic acid antisense oligonucleotide inhibits Bcl-2 and Bcl-xL expression and facilitates tumor cell apoptosis
-
Simoes-Wust,A.P., Hopkins-Donaldson,S., Sigrist,B., Belyanskaya,L., Stahel,R.A. and Zangemeister-Wittke,U. (2004) A functionally improved locked nucleic acid antisense oligonucleotide inhibits Bcl-2 and Bcl-xL expression and facilitates tumor cell apoptosis. Oligonucleotides, 14, 199-209.
-
(2004)
Oligonucleotides
, vol.14
, pp. 199-209
-
-
Simoes-Wust, A.P.1
Hopkins-Donaldson, S.2
Sigrist, B.3
Belyanskaya, L.4
Stahel, R.A.5
Zangemeister-Wittke, U.6
-
43
-
-
11844296704
-
Oligonucleotides and oligonucleotide conjugates: A new approach for cancer treatment
-
Da Ros,T., Spalluto,G., Prato,M., Saison-Behmoaras,T., Boutorine,A. and Cacciari,B. (2005) Oligonucleotides and oligonucleotide conjugates: A new approach for cancer treatment. Curr. Med. Chem., 12, 71-88.
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 71-88
-
-
Da Ros, T.1
Spalluto, G.2
Prato, M.3
Saison-Behmoaras, T.4
Boutorine, A.5
Cacciari, B.6
-
44
-
-
0344011088
-
Expanding the design horizon of antisense oligonucleotides with alpha-L-LNA
-
Frieden,M., Christensen,S.M., Mikkelsen,N.D., Rosenbohm,C., Thrue,C.A., Westergaard,M., Hansen,H.F., Orum,H. and Koch,T. (2003) Expanding the design horizon of antisense oligonucleotides with alpha-L-LNA. Nucleic Acids Res., 31, 6365-6372.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 6365-6372
-
-
Frieden, M.1
Christensen, S.M.2
Mikkelsen, N.D.3
Rosenbohm, C.4
Thrue, C.A.5
Westergaard, M.6
Hansen, H.F.7
Orum, H.8
Koch, T.9
-
45
-
-
0141819348
-
Nuclease stability of LNA oligonucleotides and LNA-DNA chimeras
-
Frieden,M., Hansen,H.F. and Koch,T. (2003) Nuclease stability of LNA oligonucleotides and LNA-DNA chimeras. Nucleosides Nucleotides Nucleic Acids, 22, 1041-1043.
-
(2003)
Nucleosides Nucleotides Nucleic Acids
, vol.22
, pp. 1041-1043
-
-
Frieden, M.1
Hansen, H.F.2
Koch, T.3
-
46
-
-
0027168725
-
Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression
-
Monia,B.P., Lesnik,E.A., Gonzalez,C., Lima,W.F., McGee,D., Guinosso,C.J., Kawasaki,A.M., Cook,P.D. and Freier,S.M. (1993) Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression. J. Biol. Chem., 268, 14514-14522.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14514-14522
-
-
Monia, B.P.1
Lesnik, E.A.2
Gonzalez, C.3
Lima, W.F.4
McGee, D.5
Guinosso, C.J.6
Kawasaki, A.M.7
Cook, P.D.8
Freier, S.M.9
-
47
-
-
0029077840
-
Characterization of fully 2′-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity
-
Cummins,L.L., Owens,S.R., Risen,L.M., Lesnik,E.A., Freier,S.M., McGee,D., Guinosso,C.J. and Cook,P.D. (1995) Characterization of fully 2′-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity. Nucleic Acids Res., 23, 2019-2024.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 2019-2024
-
-
Cummins, L.L.1
Owens, S.R.2
Risen, L.M.3
Lesnik, E.A.4
Freier, S.M.5
McGee, D.6
Guinosso, C.J.7
Cook, P.D.8
-
48
-
-
15844400778
-
Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras
-
Monia,B.P., Johnston,J.F., Sasmor,H. and Cummins,L.L. (1996) Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras. J. Biol. Chem., 271, 14533-14540.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14533-14540
-
-
Monia, B.P.1
Johnston, J.F.2
Sasmor, H.3
Cummins, L.L.4
-
49
-
-
18844455464
-
Second generation of antisense oligonucleotides. From nuclease resistance to biological efficacy in animals
-
Altmann,K.H., Dean,N.M., Fabbro,D., Freier,S.M., Geiger,T., Haener,R., Huesken,D., Martin,P., Monia,B.P., Muller,M. et al. (1996) Second generation of antisense oligonucleotides. From nuclease resistance to biological efficacy in animals. Chimia, 50, 168-176.
-
(1996)
Chimia
, vol.50
, pp. 168-176
-
-
Altmann, K.H.1
Dean, N.M.2
Fabbro, D.3
Freier, S.M.4
Geiger, T.5
Haener, R.6
Huesken, D.7
Martin, P.8
Monia, B.P.9
Muller, M.10
-
50
-
-
0030727765
-
The ups and downs of nucleic acid duplex stability: Structure-stability studies on chemically-modified DNA:RNA duplexes
-
Freier,S.M. and Altmann,K.H. (1997) The ups and downs of nucleic acid duplex stability: Structure-stability studies on chemically-modified DNA:RNA duplexes. Nucleic Acids Res., 25, 4429-4443.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 4429-4443
-
-
Freier, S.M.1
Altmann, K.H.2
-
51
-
-
0035119936
-
Pharmacokinetic properties of 2′-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats
-
Geary,R.S., Watanabe,T.A., Truong,L., Freier,S., Lesnik,E.A., Sioufi,N.B., Sasmor,H., Manoharan,M. and Levin,A.A. (2001) Pharmacokinetic properties of 2′-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats. J. Pharmacol. Exp. Ther., 296, 890-897.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 890-897
-
-
Geary, R.S.1
Watanabe, T.A.2
Truong, L.3
Freier, S.4
Lesnik, E.A.5
Sioufi, N.B.6
Sasmor, H.7
Manoharan, M.8
Levin, A.A.9
-
52
-
-
4344589884
-
Structural requirements at the catalytic site of the heteroduplex substrate for human RNase H1 catalysis
-
Lima,W.F., Nichols,J.G., Wu,H., Prakash,T.P., Migawa,M.T., Wyrzykiewicz,T.K., Bhat,B. and Crooke,S.T. (2004) Structural requirements at the catalytic site of the heteroduplex substrate for human RNase H1 catalysis. J. Biol. Chem., 279, 36317-36326.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 36317-36326
-
-
Lima, W.F.1
Nichols, J.G.2
Wu, H.3
Prakash, T.P.4
Migawa, M.T.5
Wyrzykiewicz, T.K.6
Bhat, B.7
Crooke, S.T.8
-
53
-
-
0033965192
-
Chemically modified oligonucleotides exhibit decreased immune stimulation in mice
-
Henry,S., Stecker,K., Brooks,D., Monteith,D., Conklin,B. and Bennett,C.F. (2000) Chemically modified oligonucleotides exhibit decreased immune stimulation in mice. J. Pharmacol. Exp. Ther., 292, 468-479.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 468-479
-
-
Henry, S.1
Stecker, K.2
Brooks, D.3
Monteith, D.4
Conklin, B.5
Bennett, C.F.6
-
54
-
-
0034501081
-
Nucleotides LXIV[1]: Synthesis hydridization and enzymatic degradation studies of 2′-O-methyloligoribonucleotides and 2′-O-methyl/deoxy gapmers
-
Cramer,H. and Pfleiderer,W. (2000) Nucleotides LXIV[1]: Synthesis hydridization and enzymatic degradation studies of 2′-O-methyloligoribonucleotides and 2′-O-methyl/deoxy gapmers. Nucleosides Nucleotides Nucleic Acids, 19, 1765-1777.
-
(2000)
Nucleosides Nucleotides Nucleic Acids
, vol.19
, pp. 1765-1777
-
-
Cramer, H.1
Pfleiderer, W.2
-
55
-
-
0024519705
-
Highly efficient chemical synthesis of 2′-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases
-
Sproat,B.S., Lamond,A.I., Beijer,B., Neuner,P. and Ryder,U. (1989) Highly efficient chemical synthesis of 2′-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases. Nucleic Acids Res., 17, 3373-3386.
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 3373-3386
-
-
Sproat, B.S.1
Lamond, A.I.2
Beijer, B.3
Neuner, P.4
Ryder, U.5
-
56
-
-
25144497136
-
The influence of locked nucleic acid residues on the thermodynamic properties of 2′-O-methyl RNA/RNA heteroduplexes
-
Kierzek,E., Ciesielska,A., Pasternak,K., Mathews,D.H., Turner,D.H. and Kierzek,R. (2005) The influence of locked nucleic acid residues on the thermodynamic properties of 2′-O-methyl RNA/RNA heteroduplexes. Nucleic Acids Res., 33, 5082-5093.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 5082-5093
-
-
Kierzek, E.1
Ciesielska, A.2
Pasternak, K.3
Mathews, D.H.4
Turner, D.H.5
Kierzek, R.6
-
57
-
-
0345064195
-
Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes
-
Boutla,A., Delidakis,C. and Tabler,M. (2003) Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes. Nucleic Acids Res., 31, 4973-4980.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 4973-4980
-
-
Boutla, A.1
Delidakis, C.2
Tabler, M.3
-
58
-
-
21244448730
-
Antisensemediated depletion reveals essential and specific functions of microRNAs in Drosophila development
-
Leaman,D., Chen,P.Y., Fak,J., Yalcin,A., Pearce,M., Unnerstall,U., Marks,D.S., Sander,C., Tuschl,T. and Gaul,U. (2005) Antisensemediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell, 121, 1097-1108.
-
(2005)
Cell
, vol.121
, pp. 1097-1108
-
-
Leaman, D.1
Chen, P.Y.2
Fak, J.3
Yalcin, A.4
Pearce, M.5
Unnerstall, U.6
Marks, D.S.7
Sander, C.8
Tuschl, T.9
Gaul, U.10
-
59
-
-
19344378192
-
Sequence-specific inhibition of small RNA function
-
Hutvagner,G., Simard,M.J., Mello,C.C. and Zamore,P.D. (2004) Sequence-specific inhibition of small RNA function. PLoS Biol., 2, E98.
-
(2004)
PLoS Biol.
, vol.2
-
-
Hutvagner, G.1
Simard, M.J.2
Mello, C.C.3
Zamore, P.D.4
-
60
-
-
20444440706
-
Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
-
Lee,Y.S., Kim,H.K., Chung,S., Kim,K.S. and Dutta,A. (2005) Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation. J. Biol. Chem., 280, 16635-16641.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16635-16641
-
-
Lee, Y.S.1
Kim, H.K.2
Chung, S.3
Kim, K.S.4
Dutta, A.5
-
61
-
-
14844364472
-
Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
-
Cheng,A.M., Byrom,M.W., Shelton,J. and Ford,L.P. (2005) Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res., 33, 1290-1297.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 1290-1297
-
-
Cheng, A.M.1
Byrom, M.W.2
Shelton, J.3
Ford, L.P.4
-
62
-
-
22244467087
-
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
-
Chan,J.A., Krichevsky,A.M. and Kosik,K.S. (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res., 65, 6029-6033.
-
(2005)
Cancer Res.
, vol.65
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
63
-
-
31144479591
-
A brain-specific microRNA regulates dendritic spine development
-
Schratt,G.M., Tuebing,F., Nigh,E.A., Kane,C.G., Sabatini,M.E., Kiebler,M. and Greenberg,M.E. (2006) A brain-specific microRNA regulates dendritic spine development. Nature, 439, 283-289.
-
(2006)
Nature
, vol.439
, pp. 283-289
-
-
Schratt, G.M.1
Tuebing, F.2
Nigh, E.A.3
Kane, C.G.4
Sabatini, M.E.5
Kiebler, M.6
Greenberg, M.E.7
-
64
-
-
33645135862
-
Anti-miRNA oligonucleotides (AMOs): Ammunition to target miRNAs implicated in human disease?
-
Weiler,J., Hunziker,J. and Hall,J. (2005) Anti-miRNA oligonucleotides (AMOs): Ammunition to target miRNAs implicated in human disease? Gene. Ther., 13, 496-502.
-
(2005)
Gene. Ther.
, vol.13
, pp. 496-502
-
-
Weiler, J.1
Hunziker, J.2
Hall, J.3
-
65
-
-
0024804759
-
Absorbance melting curves of RNA
-
Puglisi,J.D. and Tinoco,I.,Jr (1989) Absorbance melting curves of RNA. Meth. Enzymol., 180, 304-325.
-
(1989)
Meth. Enzymol.
, vol.180
, pp. 304-325
-
-
Puglisi, J.D.1
Tinoco Jr., I.2
-
66
-
-
0020674698
-
Base-stacking and base-pairing contributions to helix stability: Thermodynamics of double-helix formation with CCGG, CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp
-
Petersheim,M. and Turner,D.H. (1983) Base-stacking and base-pairing contributions to helix stability: Thermodynamics of double-helix formation with CCGG, CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp. Biochemistry, 22, 256-263.
-
(1983)
Biochemistry
, vol.22
, pp. 256-263
-
-
Petersheim, M.1
Turner, D.H.2
-
67
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson,S.M., Grosshans,H., Shingara,J., Byrom,M., Jarvis,R., Cheng,A., Labourier,E., Reinert,K.L., Brown,D. and Slack,F.J. (2005) RAS is regulated by the let-7 microRNA family. Cell, 120, 635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
Byrom, M.4
Jarvis, R.5
Cheng, A.6
Labourier, E.7
Reinert, K.L.8
Brown, D.9
Slack, F.J.10
-
68
-
-
25444520537
-
miR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino,A., Calin,G.A., Fabbri,M., Iorio,M.V., Ferracin,M., Shimizu,M., Wojcik,S.E., Aqeilan,R.I., Zupo,S., Dono,M. et al. (2005) miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl Acad. Sci. USA, 102, 13944-13949.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
Iorio, M.V.4
Ferracin, M.5
Shimizu, M.6
Wojcik, S.E.7
Aqeilan, R.I.8
Zupo, S.9
Dono, M.10
-
69
-
-
20444479428
-
c-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell,K.A., Wentzel,E.A., Zeller,K.I., Dang,C.V. and Mendell,J.T. (2005) c-Myc-regulated microRNAs modulate E2F1 expression. Nature, 435, 839-843.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
70
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim,L.P., Lau,N.C., Garrett-Engele,P., Grimson,A., Schelter,J.M., Castle,J., Bartel,D.P., Linsley,P.S. and Johnson,J.M. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature, 433, 769-773.
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
Castle, J.6
Bartel, D.P.7
Linsley, P.S.8
Johnson, J.M.9
-
71
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes and microRNA targets
-
Lewis,B.P., Burge,C.B. and Bartel,D.P. (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes and microRNA targets. Cell, 120, 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
72
-
-
0037418839
-
Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
-
Brennecke,J., Hipfner,D.R., Stark,A., Russell,R.B. and Cohen,S.M. (2003) Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell, 113, 25-36.
-
(2003)
Cell
, vol.113
, pp. 25-36
-
-
Brennecke, J.1
Hipfner, D.R.2
Stark, A.3
Russell, R.B.4
Cohen, S.M.5
-
73
-
-
6944246368
-
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and othere developmentally regulated patterns of vertebrate microRNA expression
-
Mansfield,J., Harfe,B.D., Nissen,R., Obenauer,J., Srineel,J., Chaudhuri,A., Farzan-Kashani,R., Zuker,M., Pasquinelli,A.E., Ruvkun,G. et al. (2004) MicroRNA-responsive 'sensor' transgenes uncover Hox-like and othere developmentally regulated patterns of vertebrate microRNA expression. Nature Genet., 36, 1076-1083.
-
(2004)
Nature Genet.
, vol.36
, pp. 1076-1083
-
-
Mansfield, J.1
Harfe, B.D.2
Nissen, R.3
Obenauer, J.4
Srineel, J.5
Chaudhuri, A.6
Farzan-Kashani, R.7
Zuker, M.8
Pasquinelli, A.E.9
Ruvkun, G.10
-
74
-
-
1242318826
-
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
-
Meister,G., Landthaler,M., Dorsett,Y. and Tuschl,T. (2004) Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA, 10, 544-550.
-
(2004)
RNA
, vol.10
, pp. 544-550
-
-
Meister, G.1
Landthaler, M.2
Dorsett, Y.3
Tuschl, T.4
-
75
-
-
0041691111
-
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
-
Zeng,Y., Yi,R. and Cullen,B.R. (2003) MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc. Natl Acad. Sci. USA, 100, 9779-9784.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 9779-9784
-
-
Zeng, Y.1
Yi, R.2
Cullen, B.R.3
-
76
-
-
0031010177
-
2′-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells
-
Baker,B.F., Lot,S.S., Condon,T.P., Cheng-Flournoy,S., Lesnik,E.A., Sasmor,H.M. and Bennett,C.F. (1997) 2′-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells. J. Biol. Chem., 272, 11994-12000.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11994-12000
-
-
Baker, B.F.1
Lot, S.S.2
Condon, T.P.3
Cheng-Flournoy, S.4
Lesnik, E.A.5
Sasmor, H.M.6
Bennett, C.F.7
-
77
-
-
0024296609
-
Physicochemical properties of phosphorothioate oligodeoxynucleotides
-
Stein,C.A., Subasinghe,C., Shinozuka,K. and Cohen,J.S. (1988) Physicochemical properties of phosphorothioate oligodeoxynucleotides. Nucleic Acids Res., 16, 3209-3221.
-
(1988)
Nucleic Acids Res.
, vol.16
, pp. 3209-3221
-
-
Stein, C.A.1
Subasinghe, C.2
Shinozuka, K.3
Cohen, J.S.4
-
78
-
-
0027479864
-
Uniformly modified 2′-deoxy-2′-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets
-
Kawasaki,A.M., Casper,M.D., Freier,S.M., Lesnik,E.A., Zounes,M.C., Cummins,L.L., Gonzalez,C. and Cook,P.D. (1993) Uniformly modified 2′-deoxy-2′-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets. J. Med. Chem., 36, 831-841.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 831-841
-
-
Kawasaki, A.M.1
Casper, M.D.2
Freier, S.M.3
Lesnik, E.A.4
Zounes, M.C.5
Cummins, L.L.6
Gonzalez, C.7
Cook, P.D.8
-
79
-
-
0033555551
-
Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression
-
McKay,R.A., Miraglia,L.J., Cummins,L.L., Owens,S.R., Sasmor,H. and Dean,N.M. (1999) Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression. J. Biol. Chem., 274, 1715-1722.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1715-1722
-
-
McKay, R.A.1
Miraglia, L.J.2
Cummins, L.L.3
Owens, S.R.4
Sasmor, H.5
Dean, N.M.6
-
80
-
-
0026048056
-
Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection
-
Hoke,G.D., Draper,K., Freier,S.M., Gonzalez,C., Driver,V.B., Zounes,M.C. and Ecker,D.J. (1991) Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection. Nucleic Acids Res., 19, 5743-5748.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 5743-5748
-
-
Hoke, G.D.1
Draper, K.2
Freier, S.M.3
Gonzalez, C.4
Driver, V.B.5
Zounes, M.C.6
Ecker, D.J.7
-
81
-
-
27744537851
-
Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
-
Gregory,R.I., Chendrimada,T.P., Cooch,N. and Shiekhattar,R. (2005) Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell, 123, 631-640.
-
(2005)
Cell
, vol.123
, pp. 631-640
-
-
Gregory, R.I.1
Chendrimada, T.P.2
Cooch, N.3
Shiekhattar, R.4
-
82
-
-
29144431656
-
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
-
Maniataki,E. and Mourelatos,Z. (2005) A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev., 19, 2979-2990.
-
(2005)
Genes Dev.
, vol.19
, pp. 2979-2990
-
-
Maniataki, E.1
Mourelatos, Z.2
-
83
-
-
27744590896
-
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
-
Matranga,C., Tomari,Y., Shin,C., Bartel,D. and Zamore,P. (2005) Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell, 123, 607-620.
-
(2005)
Cell
, vol.123
, pp. 607-620
-
-
Matranga, C.1
Tomari, Y.2
Shin, C.3
Bartel, D.4
Zamore, P.5
-
84
-
-
28444437427
-
Slicer function of Drosophila Argonautes and its involvement in RISC formation
-
Miyoshi,K., Tsukumo,H., Nagami,T., Siomi,H. and Siomi,M.C. (2005) Slicer function of Drosophila Argonautes and its involvement in RISC formation. Genes Dev., 19, 2837-2848.
-
(2005)
Genes Dev.
, vol.19
, pp. 2837-2848
-
-
Miyoshi, K.1
Tsukumo, H.2
Nagami, T.3
Siomi, H.4
Siomi, M.C.5
-
85
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
Chendrimada,T.P., Gregory,R.I., Kumaraswamy,E., Norman,J., Cooch,N., Nishikura,K. and Shiekhattar,R. (2005) TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature, 436, 740-744.
-
(2005)
Nature
, vol.436
, pp. 740-744
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
Norman, J.4
Cooch, N.5
Nishikura, K.6
Shiekhattar, R.7
-
86
-
-
15844402005
-
Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
-
Parker,J.S., Roe,S.M. and Barford,D. (2005) Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex. Nature, 434, 663-666.
-
(2005)
Nature
, vol.434
, pp. 663-666
-
-
Parker, J.S.1
Roe, S.M.2
Barford, D.3
-
87
-
-
15844371219
-
Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
-
Ma,J.B., Yuan,Y.R., Meister,G., Pei,Y., Tuschl,T. and Patel,D.J. (2005) Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature, 434, 666-670.
-
(2005)
Nature
, vol.434
, pp. 666-670
-
-
Ma, J.B.1
Yuan, Y.R.2
Meister, G.3
Pei, Y.4
Tuschl, T.5
Patel, D.J.6
-
88
-
-
32544460452
-
The role of PACT in the RNA silencing pathway
-
Lee,Y., Hur,I., Park,S.Y., Kim,Y.K., Suh,M.R. and Kim,V.N. (2006) The role of PACT in the RNA silencing pathway. EMBO. J., 25, 522-532.
-
(2006)
EMBO. J.
, vol.25
, pp. 522-532
-
-
Lee, Y.1
Hur, I.2
Park, S.Y.3
Kim, Y.K.4
Suh, M.R.5
Kim, V.N.6
-
89
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee,Y., Ahn,C., Han,J., Choi,H., Kim,J., Yim,J., Lee,J., Provost,P., Radmark,O., Kim,S. et al. (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature, 425, 415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
-
90
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund,E., Guttinger,S., Calado,A., Dahlberg,J.E. and Kutay,U. (2004) Nuclear export of microRNA precursors. Science, 303, 95-98.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
91
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi,R., Qin,Y., Macara,I.G. and Cullen,B.R. (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev., 17, 3011-3016.
-
(2003)
Genes Dev.
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
92
-
-
0034653783
-
Effects of RNA secondary structure on cellular antisense activity
-
Vickers,T.A., Wyatt,J.R. and Freier,S.M. (2000) Effects of RNA secondary structure on cellular antisense activity. Nucleic Acids Res., 28, 1340-1347.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 1340-1347
-
-
Vickers, T.A.1
Wyatt, J.R.2
Freier, S.M.3
-
93
-
-
26844440157
-
Regulating gene expression through RNA nuclear retention
-
Prasanth,K.V., Prasanth,S.G., Xuan,Z., Hearn,S., Freier,S.M., Bennett,C.F., Zhang,M.Q. and Spector,D.L. (2005) Regulating gene expression through RNA nuclear retention. Cell, 123, 249-263.
-
(2005)
Cell
, vol.123
, pp. 249-263
-
-
Prasanth, K.V.1
Prasanth, S.G.2
Xuan, Z.3
Hearn, S.4
Freier, S.M.5
Bennett, C.F.6
Zhang, M.Q.7
Spector, D.L.8
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