A cytosine analog that confers enhanced potency to antisense oligonucleotides

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 7, 1999, Pages 3513-3518

  Flanagan, W Michael ^a,b   Wolf, John J ^a   Olson, Peter ^a   Grant, Debbie ^a   Lin, Kuei Ying ^a   Wagner, Richard W ^a,c   Matteucci, Mark D ^a  

^a GILEAD SCIENCES   (United States)

^b Sunesis Pharmaceuticals Inc   (United States)

^c Phylos Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYTOSINE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; RIBONUCLEASE;

ANIMAL CELL; ARTICLE; BASE MISPAIRING; BINDING AFFINITY; CHEMICAL STRUCTURE; DNA MODIFICATION; DNA RNA HYBRIDIZATION; ENZYME ACTIVITY; MOLECULAR STABILITY; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; CELL CYCLE PROTEINS; CELL LINE; CERCOPITHECUS AETHIOPS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOSINE; DRUG DESIGN; ENZYME INHIBITORS; KIDNEY; MICROTUBULE-ASSOCIATED PROTEINS; NUCLEIC ACID HYBRIDIZATION; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; OXAZINES; RNA, MESSENGER; STRUCTURE-ACTIVITY RELATIONSHIP; THIONUCLEOTIDES; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 0033616610     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.7.3513     Document Type: Article

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