메뉴 건너뛰기




Volumn 32, Issue 20, 2004, Pages 5991-6000

RNA interference using boranophosphate siRNAs: Structure-activity relationships

Author keywords

[No Author keywords available]

Indexed keywords

BORANE DERIVATIVE; COMPLEMENTARY RNA; NUCLEASE; PHOSPHOROTHIOIC ACID; SMALL INTERFERING RNA;

EID: 11344257391     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh936     Document Type: Article
Times cited : (248)

References (40)
  • 2
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus,M.T. and Sharp,P.A. (2002) Gene silencing in mammals by small interfering RNAs. Nature Rev. Genet., 3, 737-747.
    • (2002) Nature Rev. Genet. , vol.3 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 3
    • 0036245743 scopus 로고    scopus 로고
    • Expanding small RNA interference
    • Tuschl,T. (2002) Expanding small RNA interference. Nat. Biotechnol., 20, 446-448.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 446-448
    • Tuschl, T.1
  • 5
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir,S.M., Lendeckel,W. and Tuschl,T. (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev., 15, 188-200.
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 6
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond,S.M., Bernstein,E., Beach,D. and Hannon,G.J. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature, 404, 293-296.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 7
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • Hammond,S.M., Boettcher,S., Caudy,A.A., Kobayashi,R. and Hannon,G.J. (2001) Argonaute2, a link between genetic and biochemical analyses of RNAi. Science, 293, 1146-1150.
    • (2001) Science , vol.293 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3    Kobayashi, R.4    Hannon, G.J.5
  • 8
    • 0037031576 scopus 로고    scopus 로고
    • Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
    • Martinez,J., Patkaniowska,A., Urlaub,H., Luhrmann,R. and Tuschl,T. (2002) Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell., 110, 563-574.
    • (2002) Cell , vol.110 , pp. 563-574
    • Martinez, J.1    Patkaniowska, A.2    Urlaub, H.3    Luhrmann, R.4    Tuschl, T.5
  • 9
    • 0141569812 scopus 로고    scopus 로고
    • Interfering with disease: Opportunities and roadblocks to harnessing RNA interference
    • Lieberman,J., Song,E., Lee,S.K. and Shankar,P. (2003) Interfering with disease: opportunities and roadblocks to harnessing RNA interference. Trends Mol. Med., 9, 397-403.
    • (2003) Trends Mol. Med. , vol.9 , pp. 397-403
    • Lieberman, J.1    Song, E.2    Lee, S.K.3    Shankar, P.4
  • 10
    • 0036721314 scopus 로고    scopus 로고
    • Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
    • Coburn,G.A. and Cullen,B.R. (2002) Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J. Virol., 76, 9225-9231.
    • (2002) J. Virol. , vol.76 , pp. 9225-9231
    • Coburn, G.A.1    Cullen, B.R.2
  • 11
    • 0037422607 scopus 로고    scopus 로고
    • Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
    • Randall,G., Grakoui,A. and Rice,C.M. (2003) Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs. Proc. Natl Acad. Sci. USA, 100, 235-240.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 235-240
    • Randall, G.1    Grakoui, A.2    Rice, C.M.3
  • 12
    • 0038032792 scopus 로고    scopus 로고
    • RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells
    • Hall,A.H. and Alexander,K.A. (2003) RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells. J. Virol., 77, 6066-6069.
    • (2003) J. Virol. , vol.77 , pp. 6066-6069
    • Hall, A.H.1    Alexander, K.A.2
  • 13
    • 0037158901 scopus 로고    scopus 로고
    • Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
    • Wilda,M., Fuchs,U., Wossmann,W. and Borkhardt,A. (2002) Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene, 21, 5716-5724.
    • (2002) Oncogene , vol.21 , pp. 5716-5724
    • Wilda, M.1    Fuchs, U.2    Wossmann, W.3    Borkhardt, A.4
  • 14
    • 0141552295 scopus 로고    scopus 로고
    • Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    • Sorensen,D.R., Leirdal,M. and Sioud,M. (2003) Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J. Mol. Biol. 327, 761-766.
    • (2003) J. Mol. Biol. , vol.327 , pp. 761-766
    • Sorensen, D.R.1    Leirdal, M.2    Sioud, M.3
  • 15
    • 0021891882 scopus 로고
    • Nucleoside phosphorothioates
    • Eckstein,F. (1985) Nucleoside phosphorothioates. Annu. Rev. Biochem., 54, 367-402.
    • (1985) Annu. Rev. Biochem. , vol.54 , pp. 367-402
    • Eckstein, F.1
  • 16
    • 0036760718 scopus 로고    scopus 로고
    • Developments in RNA chemistry, a personal view
    • Eckstein,F. (2002) Developments in RNA chemistry, a personal view. Biochimie, 84, 841-848.
    • (2002) Biochimie , vol.84 , pp. 841-848
    • Eckstein, F.1
  • 17
    • 0030868820 scopus 로고    scopus 로고
    • Identification of aptamers against the DNA template for in vitro transcription of the HIV-1 TAR element
    • Boiziau,C.Dausse,E., Mishra,R., Duconge,F. and Toulme,J.J. (1997) Identification of aptamers against the DNA template for in vitro transcription of the HIV-1 TAR element. Antisense Nucleic Acid Drug Dev., 7, 369-380.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 369-380
    • Boiziau, C.1    Dausse, E.2    Mishra, R.3    Duconge, F.4    Toulme, J.J.5
  • 18
    • 11344265281 scopus 로고    scopus 로고
    • Summary
    • Chadwick,D.J. and Cardew,G. (ed.) Ciba Foundation Symposium 209, John Wiley, NY
    • Caruthers,M.H. (1997) Summary. In Chadwick,D.J. and Cardew,G. (ed.) Oligonucleotides as Therapeutic Agents. Ciba Foundation Symposium 209, John Wiley, NY, pp. 235-239.
    • (1997) Oligonucleotides As Therapeutic Agents , pp. 235-239
    • Caruthers, M.H.1
  • 19
    • 0037440005 scopus 로고    scopus 로고
    • Tolerance for mutations and chemical modifications in a siRNA
    • Amarzguioui,M., Holen,T., Babaie,E. and Prydz,H. (2003) Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res., 31, 589-595.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 589-595
    • Amarzguioui, M.1    Holen, T.2    Babaie, E.3    Prydz, H.4
  • 22
  • 23
    • 0033634682 scopus 로고    scopus 로고
    • Functional anatomy of a dsRNA trigger: Differential requirement for the two trigger strands in RNA interference
    • Parrish,S., Fleenor,J., Xu,S., Mello,C. and Fire,A. (2000) Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference. Mol. Cell., 6, 1077-1087.
    • (2000) Mol. Cell. , vol.6 , pp. 1077-1087
    • Parrish, S.1    Fleenor, J.2    Xu, S.3    Mello, C.4    Fire, A.5
  • 24
    • 0002557775 scopus 로고    scopus 로고
    • Chemical synthesis and purification of phosphorothioate antisense oligonucleotides
    • Hartmann,G. and Endres,S. (eds) Kluwer Academic Publisher, Boston, MA
    • Sanghvi,Y.S., Anrade,M., Deshmukh,R.R., Holmberg,L., Scozzari,A.N. and Cole,D.L. (1999) Chemical synthesis and purification of phosphorothioate antisense oligonucleotides. In: Hartmann,G. and Endres,S. (eds) Manual of Antisense Methodology. Kluwer Academic Publisher, Boston, MA, pp. 3-24.
    • (1999) Manual of Antisense Methodology , pp. 3-24
    • Sanghvi, Y.S.1    Anrade, M.2    Deshmukh, R.R.3    Holmberg, L.4    Scozzari, A.N.5    Cole, D.L.6
  • 25
  • 26
    • 11344251096 scopus 로고    scopus 로고
    • Diastereomers of 5′-O-adenosyl 3′-O-uridyl Boranophosphate [UpBH3)A]: Synthesis and nuclease resistant property
    • Oxford University Press, Oxford, UK
    • He,K. and Ramsay Shaw,B. (1999) Diastereomers of 5′-O adenosyl 3′-O-uridyl Boranophosphate [UpBH3)A]: synthesis and nuclease resistant property. Symposium on RNA Biology III: RNA, Tool and Target in Nucleic Acids Symposium Series No. 41, Oxford University Press, Oxford, UK, pp. 99-100.
    • (1999) Symposium on RNA Biology III: RNA, Tool and Target in Nucleic Acids Symposium Series , Issue.41 , pp. 99-100
    • He, K.1    Ramsay Shaw, B.2
  • 29
    • 11344282872 scopus 로고    scopus 로고
    • Synthesis and properties of boranophosphate nucleic acids
    • PhD Dissertation. Duke University, Durham, NC
    • He,K. (2000). Synthesis and properties of boranophosphate nucleic acids. PhD Dissertation. Duke University, Durham, NC.
    • (2000)
    • He, K.1
  • 30
    • 0034958945 scopus 로고    scopus 로고
    • Boranophosphates as mimics of natural phosphodiesters in DNA
    • Summers,J.S. and Shaw,B.R. (2001) Boranophosphates as mimics of natural phosphodiesters in DNA. Curr. Med. Chem. 8, 1147-1155.
    • (2001) Curr. Med. Chem. , vol.8 , pp. 1147-1155
    • Summers, J.S.1    Shaw, B.R.2
  • 31
    • 0033990454 scopus 로고    scopus 로고
    • Boranophosphate backbone: A mimic of phosphodiesters, phosphorothioates, and methylphosphonates
    • Ramsay Shaw,B., Sergueev,D.S., He,K., Porter,K., Summers,J., Sergueeva,Z. and Rait,V. (1999) Boranophosphate backbone: a mimic of phosphodiesters, phosphorothioates, and methylphosphonates. Meth. Enzymol., 313, 226-257.
    • (1999) Meth. Enzymol. , vol.313 , pp. 226-257
    • Ramsay Shaw, B.1    Sergueev, D.S.2    He, K.3    Porter, K.4    Summers, J.5    Sergueeva, Z.6    Rait, V.7
  • 33
    • 0029934395 scopus 로고    scopus 로고
    • Hydrolysis of thymidine boranomonophosphate and stepwise deuterium substitution of the borane hydrogens. 31P and 11B NMR studies
    • Li,H., Hardin,C. and Ramsay Shaw,B. (1996) Hydrolysis of thymidine boranomonophosphate and stepwise deuterium substitution of the borane hydrogens. 31P and 11B NMR studies. J. Am. Chem. Soc., 118, 6606-6614.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 6606-6614
    • Li, H.1    Hardin, C.2    Ramsay Shaw, B.3
  • 34
    • 0000287564 scopus 로고    scopus 로고
    • Synthesis and separation of diastereomers of ribonucleoside 5′-(alpha-P-Borano)triphosphates
    • He,K., Hasan,A., Krzyzanowska,B. and Ramsay Shaw,B. (1998) Synthesis and separation of diastereomers of ribonucleoside 5′-(alpha-P-Borano)triphosphates. J. Org. Chem., 63, 5769-5773.
    • (1998) J. Org. Chem. , vol.63 , pp. 5769-5773
    • He, K.1    Hasan, A.2    Krzyzanowska, B.3    Ramsay Shaw, B.4
  • 35
    • 0012756249 scopus 로고    scopus 로고
    • RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase
    • Donze,O. and Picard,D. (2002) RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res., 30, e46.
    • (2002) Nucleic Acids Res. , vol.30
    • Donze, O.1    Picard, D.2
  • 36
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir,S.M., Martinez,J., Patkaniowska,A., Lendeckel,W. and Tuschl,T. (2001) Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J., 20 6877-6888.
    • (2001) EMBO J. , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 38
    • 0041331496 scopus 로고    scopus 로고
    • siRNA function in RNAi: A chemical modification analysis
    • Chiu,Y.L. and Rana,T.M. (2003) siRNA function in RNAi: a chemical modification analysis. RNA, 9, 1034-1048.
    • (2003) RNA , vol.9 , pp. 1034-1048
    • Chiu, Y.L.1    Rana, T.M.2
  • 39
    • 0032879978 scopus 로고    scopus 로고
    • GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation
    • Cikaluk,D.E., Tahbaz,N., Hendricks,L.C., DiMattia,G.E., Hansen,D., Pilgrim,D. and Hobman,T.C. (1999) GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation. Mol. Biol. Cell., 10, 3357-3372.
    • (1999) Mol. Biol. Cell. , vol.10 , pp. 3357-3372
    • Cikaluk, D.E.1    Tahbaz, N.2    Hendricks, L.C.3    DiMattia, G.E.4    Hansen, D.5    Pilgrim, D.6    Hobman, T.C.7
  • 40
    • 0037144546 scopus 로고    scopus 로고
    • A microRNA in a multiple-turnover RNAi enzyme complex
    • Hutvagner,G. and Zamore,P.D. (2002) A microRNA in a multiple-turnover RNAi enzyme complex. Science, 297, 2056-2060.
    • (2002) Science , vol.297 , pp. 2056-2060
    • Hutvagner, G.1    Zamore, P.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.