-
2
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
McManus,M.T. and Sharp,P.A. (2002) Gene silencing in mammals by small interfering RNAs. Nature Rev. Genet., 3, 737-747.
-
(2002)
Nature Rev. Genet.
, vol.3
, pp. 737-747
-
-
McManus, M.T.1
Sharp, P.A.2
-
3
-
-
0036245743
-
Expanding small RNA interference
-
Tuschl,T. (2002) Expanding small RNA interference. Nat. Biotechnol., 20, 446-448.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 446-448
-
-
Tuschl, T.1
-
5
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir,S.M., Lendeckel,W. and Tuschl,T. (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev., 15, 188-200.
-
(2001)
Genes Dev.
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
6
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond,S.M., Bernstein,E., Beach,D. and Hannon,G.J. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature, 404, 293-296.
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
7
-
-
0035839109
-
Argonaute2, a link between genetic and biochemical analyses of RNAi
-
Hammond,S.M., Boettcher,S., Caudy,A.A., Kobayashi,R. and Hannon,G.J. (2001) Argonaute2, a link between genetic and biochemical analyses of RNAi. Science, 293, 1146-1150.
-
(2001)
Science
, vol.293
, pp. 1146-1150
-
-
Hammond, S.M.1
Boettcher, S.2
Caudy, A.A.3
Kobayashi, R.4
Hannon, G.J.5
-
8
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez,J., Patkaniowska,A., Urlaub,H., Luhrmann,R. and Tuschl,T. (2002) Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell., 110, 563-574.
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Luhrmann, R.4
Tuschl, T.5
-
9
-
-
0141569812
-
Interfering with disease: Opportunities and roadblocks to harnessing RNA interference
-
Lieberman,J., Song,E., Lee,S.K. and Shankar,P. (2003) Interfering with disease: opportunities and roadblocks to harnessing RNA interference. Trends Mol. Med., 9, 397-403.
-
(2003)
Trends Mol. Med.
, vol.9
, pp. 397-403
-
-
Lieberman, J.1
Song, E.2
Lee, S.K.3
Shankar, P.4
-
10
-
-
0036721314
-
Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
-
Coburn,G.A. and Cullen,B.R. (2002) Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J. Virol., 76, 9225-9231.
-
(2002)
J. Virol.
, vol.76
, pp. 9225-9231
-
-
Coburn, G.A.1
Cullen, B.R.2
-
11
-
-
0037422607
-
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
-
Randall,G., Grakoui,A. and Rice,C.M. (2003) Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs. Proc. Natl Acad. Sci. USA, 100, 235-240.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 235-240
-
-
Randall, G.1
Grakoui, A.2
Rice, C.M.3
-
12
-
-
0038032792
-
RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells
-
Hall,A.H. and Alexander,K.A. (2003) RNA interference of human papillomavirus type 18 E6 and E7 induces senescence in HeLa cells. J. Virol., 77, 6066-6069.
-
(2003)
J. Virol.
, vol.77
, pp. 6066-6069
-
-
Hall, A.H.1
Alexander, K.A.2
-
13
-
-
0037158901
-
Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
-
Wilda,M., Fuchs,U., Wossmann,W. and Borkhardt,A. (2002) Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene, 21, 5716-5724.
-
(2002)
Oncogene
, vol.21
, pp. 5716-5724
-
-
Wilda, M.1
Fuchs, U.2
Wossmann, W.3
Borkhardt, A.4
-
14
-
-
0141552295
-
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
-
Sorensen,D.R., Leirdal,M. and Sioud,M. (2003) Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J. Mol. Biol. 327, 761-766.
-
(2003)
J. Mol. Biol.
, vol.327
, pp. 761-766
-
-
Sorensen, D.R.1
Leirdal, M.2
Sioud, M.3
-
15
-
-
0021891882
-
Nucleoside phosphorothioates
-
Eckstein,F. (1985) Nucleoside phosphorothioates. Annu. Rev. Biochem., 54, 367-402.
-
(1985)
Annu. Rev. Biochem.
, vol.54
, pp. 367-402
-
-
Eckstein, F.1
-
16
-
-
0036760718
-
Developments in RNA chemistry, a personal view
-
Eckstein,F. (2002) Developments in RNA chemistry, a personal view. Biochimie, 84, 841-848.
-
(2002)
Biochimie
, vol.84
, pp. 841-848
-
-
Eckstein, F.1
-
17
-
-
0030868820
-
Identification of aptamers against the DNA template for in vitro transcription of the HIV-1 TAR element
-
Boiziau,C.Dausse,E., Mishra,R., Duconge,F. and Toulme,J.J. (1997) Identification of aptamers against the DNA template for in vitro transcription of the HIV-1 TAR element. Antisense Nucleic Acid Drug Dev., 7, 369-380.
-
(1997)
Antisense Nucleic Acid Drug Dev.
, vol.7
, pp. 369-380
-
-
Boiziau, C.1
Dausse, E.2
Mishra, R.3
Duconge, F.4
Toulme, J.J.5
-
18
-
-
11344265281
-
Summary
-
Chadwick,D.J. and Cardew,G. (ed.) Ciba Foundation Symposium 209, John Wiley, NY
-
Caruthers,M.H. (1997) Summary. In Chadwick,D.J. and Cardew,G. (ed.) Oligonucleotides as Therapeutic Agents. Ciba Foundation Symposium 209, John Wiley, NY, pp. 235-239.
-
(1997)
Oligonucleotides As Therapeutic Agents
, pp. 235-239
-
-
Caruthers, M.H.1
-
19
-
-
0037440005
-
Tolerance for mutations and chemical modifications in a siRNA
-
Amarzguioui,M., Holen,T., Babaie,E. and Prydz,H. (2003) Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res., 31, 589-595.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 589-595
-
-
Amarzguioui, M.1
Holen, T.2
Babaie, E.3
Prydz, H.4
-
20
-
-
0038606999
-
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
-
Czauderna,F., Fechtner,M., Dames,S., Aygun,H., Klippel,A., Pronk,G.J., Giese,K. and Kaufmann,J. (2003) Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res., 31, 2705-2716.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2705-2716
-
-
Czauderna, F.1
Fechtner, M.2
Dames, S.3
Aygun, H.4
Klippel, A.5
Pronk, G.J.6
Giese, K.7
Kaufmann, J.8
-
21
-
-
0038385504
-
RNA interference in mammalian cells by chemically-modified RNA
-
Braasch,D.A., Jensen,S., Liu,Y., Kaur,K., Arar,K., White,M.A. and Corey,D.R. (2003) RNA interference in mammalian cells by chemically-modified RNA. Biochemistry, 42, 7967-7975.
-
(2003)
Biochemistry
, vol.42
, pp. 7967-7975
-
-
Braasch, D.A.1
Jensen, S.2
Liu, Y.3
Kaur, K.4
Arar, K.5
White, M.A.6
Corey, D.R.7
-
22
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
Harborth,J., ElbashirS.M., Vandenburgh,K., Manninga,H., Scaringe,S.A., Weber,K. and Tuschl,T. (2003) Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Antisense Nucleic Acid Drug Dev., 13, 83-105.
-
(2003)
Antisense Nucleic Acid Drug Dev.
, vol.13
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
Manninga, H.4
Scaringe, S.A.5
Weber, K.6
Tuschl, T.7
-
23
-
-
0033634682
-
Functional anatomy of a dsRNA trigger: Differential requirement for the two trigger strands in RNA interference
-
Parrish,S., Fleenor,J., Xu,S., Mello,C. and Fire,A. (2000) Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference. Mol. Cell., 6, 1077-1087.
-
(2000)
Mol. Cell.
, vol.6
, pp. 1077-1087
-
-
Parrish, S.1
Fleenor, J.2
Xu, S.3
Mello, C.4
Fire, A.5
-
24
-
-
0002557775
-
Chemical synthesis and purification of phosphorothioate antisense oligonucleotides
-
Hartmann,G. and Endres,S. (eds) Kluwer Academic Publisher, Boston, MA
-
Sanghvi,Y.S., Anrade,M., Deshmukh,R.R., Holmberg,L., Scozzari,A.N. and Cole,D.L. (1999) Chemical synthesis and purification of phosphorothioate antisense oligonucleotides. In: Hartmann,G. and Endres,S. (eds) Manual of Antisense Methodology. Kluwer Academic Publisher, Boston, MA, pp. 3-24.
-
(1999)
Manual of Antisense Methodology
, pp. 3-24
-
-
Sanghvi, Y.S.1
Anrade, M.2
Deshmukh, R.R.3
Holmberg, L.4
Scozzari, A.N.5
Cole, D.L.6
-
25
-
-
0030842860
-
Direct PCR sequencing with boronated nucleotides
-
Porter,K.W., Briley,J.D. and Ramsay Shaw,B. (1997) Direct PCR sequencing with boronated nucleotides. Nucleic Acids Res., 25 1611-1617.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 1611-1617
-
-
Porter, K.W.1
Briley, J.D.2
Ramsay Shaw, B.3
-
26
-
-
11344251096
-
Diastereomers of 5′-O-adenosyl 3′-O-uridyl Boranophosphate [UpBH3)A]: Synthesis and nuclease resistant property
-
Oxford University Press, Oxford, UK
-
He,K. and Ramsay Shaw,B. (1999) Diastereomers of 5′-O adenosyl 3′-O-uridyl Boranophosphate [UpBH3)A]: synthesis and nuclease resistant property. Symposium on RNA Biology III: RNA, Tool and Target in Nucleic Acids Symposium Series No. 41, Oxford University Press, Oxford, UK, pp. 99-100.
-
(1999)
Symposium on RNA Biology III: RNA, Tool and Target in Nucleic Acids Symposium Series
, Issue.41
, pp. 99-100
-
-
He, K.1
Ramsay Shaw, B.2
-
27
-
-
5444224668
-
Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA
-
Ramsay Shaw,B., Dobrikov,M., Wang,X, Wan,J., He,K., Lin,J., Li,P., Rait,V., Sergueeva,Z.A. and Sergueev,D. (2003) Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA. Ann. N. Y. Acad. Sci., 1002, 12-39.
-
(2003)
Ann. N. Y. Acad. Sci.
, vol.1002
, pp. 12-39
-
-
Ramsay Shaw, B.1
Dobrikov, M.2
Wang, X.3
Wan, J.4
He, K.5
Lin, J.6
Li, P.7
Rait, V.8
Sergueeva, Z.A.9
Sergueev, D.10
-
28
-
-
0037085736
-
Boron-containing aptamers to ATP
-
Lato,S.M., Ozerova,N.D., He,K., Sergueeva,Z., Shaw,B.R. and Burke,D.H. (2002) Boron-containing aptamers to ATP. Nucleic Acids Res. 30, 1401-1407.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 1401-1407
-
-
Lato, S.M.1
Ozerova, N.D.2
He, K.3
Sergueeva, Z.4
Shaw, B.R.5
Burke, D.H.6
-
29
-
-
11344282872
-
Synthesis and properties of boranophosphate nucleic acids
-
PhD Dissertation. Duke University, Durham, NC
-
He,K. (2000). Synthesis and properties of boranophosphate nucleic acids. PhD Dissertation. Duke University, Durham, NC.
-
(2000)
-
-
He, K.1
-
30
-
-
0034958945
-
Boranophosphates as mimics of natural phosphodiesters in DNA
-
Summers,J.S. and Shaw,B.R. (2001) Boranophosphates as mimics of natural phosphodiesters in DNA. Curr. Med. Chem. 8, 1147-1155.
-
(2001)
Curr. Med. Chem.
, vol.8
, pp. 1147-1155
-
-
Summers, J.S.1
Shaw, B.R.2
-
31
-
-
0033990454
-
Boranophosphate backbone: A mimic of phosphodiesters, phosphorothioates, and methylphosphonates
-
Ramsay Shaw,B., Sergueev,D.S., He,K., Porter,K., Summers,J., Sergueeva,Z. and Rait,V. (1999) Boranophosphate backbone: a mimic of phosphodiesters, phosphorothioates, and methylphosphonates. Meth. Enzymol., 313, 226-257.
-
(1999)
Meth. Enzymol.
, vol.313
, pp. 226-257
-
-
Ramsay Shaw, B.1
Sergueev, D.S.2
He, K.3
Porter, K.4
Summers, J.5
Sergueeva, Z.6
Rait, V.7
-
32
-
-
0027324722
-
Hypolipidemic activity of boronated nucleosides and nucleotides in rodents
-
Hall,I.H., Burnham,B.S., Rajendran,K.G., Chen,S.Y., Sood,A., Spielvogel,B.F. and Ramsay Shaw,B. (1993) Hypolipidemic activity of boronated nucleosides and nucleotides in rodents. Biomed. Pharmacother., 47, 79-87.
-
(1993)
Biomed. Pharmacother.
, vol.47
, pp. 79-87
-
-
Hall, I.H.1
Burnham, B.S.2
Rajendran, K.G.3
Chen, S.Y.4
Sood, A.5
Spielvogel, B.F.6
Ramsay Shaw, B.7
-
33
-
-
0029934395
-
Hydrolysis of thymidine boranomonophosphate and stepwise deuterium substitution of the borane hydrogens. 31P and 11B NMR studies
-
Li,H., Hardin,C. and Ramsay Shaw,B. (1996) Hydrolysis of thymidine boranomonophosphate and stepwise deuterium substitution of the borane hydrogens. 31P and 11B NMR studies. J. Am. Chem. Soc., 118, 6606-6614.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 6606-6614
-
-
Li, H.1
Hardin, C.2
Ramsay Shaw, B.3
-
34
-
-
0000287564
-
Synthesis and separation of diastereomers of ribonucleoside 5′-(alpha-P-Borano)triphosphates
-
He,K., Hasan,A., Krzyzanowska,B. and Ramsay Shaw,B. (1998) Synthesis and separation of diastereomers of ribonucleoside 5′-(alpha-P-Borano)triphosphates. J. Org. Chem., 63, 5769-5773.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 5769-5773
-
-
He, K.1
Hasan, A.2
Krzyzanowska, B.3
Ramsay Shaw, B.4
-
35
-
-
0012756249
-
RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase
-
Donze,O. and Picard,D. (2002) RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res., 30, e46.
-
(2002)
Nucleic Acids Res.
, vol.30
-
-
Donze, O.1
Picard, D.2
-
36
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
Elbashir,S.M., Martinez,J., Patkaniowska,A., Lendeckel,W. and Tuschl,T. (2001) Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J., 20 6877-6888.
-
(2001)
EMBO J.
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
Martinez, J.2
Patkaniowska, A.3
Lendeckel, W.4
Tuschl, T.5
-
37
-
-
0037443089
-
siRNAs can function as miRNAs
-
Doench,J.G., Petersen,C.P. and Sharp,P.A. (2003) siRNAs can function as miRNAs. Genes Dev., 17, 438-442.
-
(2003)
Genes Dev.
, vol.17
, pp. 438-442
-
-
Doench, J.G.1
Petersen, C.P.2
Sharp, P.A.3
-
38
-
-
0041331496
-
siRNA function in RNAi: A chemical modification analysis
-
Chiu,Y.L. and Rana,T.M. (2003) siRNA function in RNAi: a chemical modification analysis. RNA, 9, 1034-1048.
-
(2003)
RNA
, vol.9
, pp. 1034-1048
-
-
Chiu, Y.L.1
Rana, T.M.2
-
39
-
-
0032879978
-
GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation
-
Cikaluk,D.E., Tahbaz,N., Hendricks,L.C., DiMattia,G.E., Hansen,D., Pilgrim,D. and Hobman,T.C. (1999) GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation. Mol. Biol. Cell., 10, 3357-3372.
-
(1999)
Mol. Biol. Cell.
, vol.10
, pp. 3357-3372
-
-
Cikaluk, D.E.1
Tahbaz, N.2
Hendricks, L.C.3
DiMattia, G.E.4
Hansen, D.5
Pilgrim, D.6
Hobman, T.C.7
-
40
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner,G. and Zamore,P.D. (2002) A microRNA in a multiple-turnover RNAi enzyme complex. Science, 297, 2056-2060.
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
|