-
1
-
-
84914595430
-
Nicotinic and muscarinic binding sites on lymphocytes of Alzheimer patients
-
A. Fisher, I. Hanin, and C. Lachman, Eds., Plenum Press, New York
-
Adem, A., Nordberg, A., Bucht, G. and Winblad, B.: Nicotinic and muscarinic binding sites on lymphocytes of Alzheimer patients. In: "Alzheimer's and Parkinson's Diseases, " A. Fisher, I. Hanin, and C. Lachman, Eds., pp. 337-344, Plenum Press, New York, 1985.
-
(1985)
Alzheimer's and Parkinson's Diseases
, pp. 337-344
-
-
Adem, A.1
Nordberg, A.2
Bucht, G.3
Winblad, B.4
-
2
-
-
0041911076
-
EEG coherence in Alzheimer's dementia
-
Adler, G., Brassen, S. and Jajcevic, A.: EEG coherence in Alzheimer's dementia. J. Neural. Transm. 110: 1051-1058, 2003.
-
(2003)
J. Neural. Transm.
, vol.110
, pp. 1051-1058
-
-
Adler, G.1
Brassen, S.2
Jajcevic, A.3
-
3
-
-
0037638809
-
Alzheimer's Disease Cooperative Study. Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: A randomized controlled trial
-
Aisen, P. S., Schafer, K. A., Grundman, M., Pfeiffer, E., Sano, M., Davis, K. L., Farlow, M. R., Jin, S., Thomas, R. G. and Thal, L. J.: Alzheimer's Disease Cooperative Study. Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: A randomized controlled trial. JAMA 289(21): 2819- 2826, 2003.
-
(2003)
JAMA
, vol.289
, Issue.21
, pp. 2819-2826
-
-
Aisen, P.S.1
Schafer, K.A.2
Grundman, M.3
Pfeiffer, E.4
Sano, M.5
Davis, K.L.6
Farlow, M.R.7
Jin, S.8
Thomas, R.G.9
Thal, L.J.10
-
6
-
-
0342865865
-
Über die anatomische Grundlage der Hutingtonschen Chorea und der choreatischen Bewegungen überhaupt.
-
Alzheimer, A.: Über die anatomische Grundlage der Hutingtonschen Chorea und der choreatischen Bewegungen überhaupt. Ztschrft. Ges. Neurol. Psychiat. 3: 566, 1911.
-
(1911)
Ztschrft. Ges. Neurol. Psychiat.
, vol.3
, pp. 566
-
-
Alzheimer, A.1
-
7
-
-
0026132255
-
On certain peculiar diseases of old age
-
Translated, with an Introduction by H. Foerstl and R. Levy, Alpha Academic Press, London
-
Alzheimer, A.: On certain peculiar diseases of old age. In: "History of Psychiatry, " Translated, with an Introduction by H. Foerstl and R. Levy, Alpha Academic Press, London, vol. 2, pp. 71-101, 1991.
-
(1991)
History of Psychiatry
, vol.2
, pp. 71-101
-
-
Alzheimer, A.1
-
8
-
-
0002919093
-
Long-term treatment with rivastigmine continues to provide benefits for up to one year
-
Geneva, Abstract 18
-
Anand, R., Hartman, R. and Messina, J.: Long-term treatment with rivastigmine continues to provide benefits for up to one year. Fifth International Geneva-Springfield Symposium on Advances in Alzheimer Therapy, Geneva, Abstract 18, 1998.
-
(1998)
Fifth International Geneva-Springfield Symposium on Advances in Alzheimer Therapy
-
-
Anand, R.1
Hartman, R.2
Messina, J.3
-
9
-
-
0025831751
-
Exact cleavage site of Alzheimer amyloid precursor in neuronal PC- 12 cells
-
Anderson, J. P., Esch, F. S., Keim, P. S., Sambamurti, K., Lieberburg, I. and Robakis, N. K.: Exact cleavage site of Alzheimer amyloid precursor in neuronal PC- 12 cells. Neurosci. Lett. 128(1): 126-128, 1991.
-
(1991)
Neurosci. Lett.
, vol.128
, Issue.1
, pp. 126-128
-
-
Anderson, J.P.1
Esch, F.S.2
Keim, P.S.3
Sambamurti, K.4
Lieberburg, I.5
Robakis, N.K.6
-
10
-
-
0035223461
-
Sites of phosphorylation in tau and factors affecting their regulation
-
Anderton, B. H., Betts, J., Blackstock, W. P., Brion, J. P., Chapman, S., Connell, J., Dayanandan, R., Gallo, J. M., Gibb, G., Hanger, D. P., Hutton, M., Kardalinou, E., Leroy, K., Lovestone, S., Mack, T., Reynolds, C. H. and Van Slegtenhorst, M.: Sites of phosphorylation in tau and factors affecting their regulation. Biochem. Soc. Symp. 2001(67): 73-80, 2001.
-
(2001)
Biochem. Soc. Symp.
, vol.2001
, Issue.67
, pp. 73-80
-
-
Anderton, B.H.1
Betts, J.2
Blackstock, W.P.3
Brion, J.P.4
Chapman, S.5
Connell, J.6
Dayanandan, R.7
Gallo, J.M.8
Gibb, G.9
Hanger, D.P.10
Hutton, M.11
Kardalinou, E.12
Leroy, K.13
Lovestone, S.14
Mack, T.15
Reynolds, C.H.16
Van Slegtenhorst, M.17
-
11
-
-
0033749394
-
Expression, purification and crystallization of human tau-protein kinase I/glycogen synthase kinase-3beta
-
Aoki, M., Iwamoto-Sugai, M., Sugiura, I., Sasaki, C., Hasegawa, T., Okumura, C., Sugio, S., Kohno, T. and Matsuzaki, T.: Expression, purification and crystallization of human tau-protein kinase I/glycogen synthase kinase-3beta. Acta Crystallogr. D Biol. Crystallogr. 56, Pt. 11: 1464-1465, 2000.
-
(2000)
Acta Crystallogr. D Biol. Crystallogr.
, vol.56
, pp. 1464-1465
-
-
Aoki, M.1
Iwamoto-Sugai, M.2
Sugiura, I.3
Sasaki, C.4
Hasegawa, T.5
Okumura, C.6
Sugio, S.7
Kohno, T.8
Matsuzaki, T.9
-
12
-
-
17044373652
-
Role for glycogen synthase kinase-3 in NK cell cytotoxicity and X-linked lymphoproliferative disease
-
Aoukati, A. and Tan, R.: Role for glycogen synthase kinase-3 in NK cell cytotoxicity and X-linked lymphoproliferative disease, J. Immunol. 174: 4551- 4558, 2005.
-
(2005)
J. Immunol.
, vol.174
, pp. 4551-4558
-
-
Aoukati, A.1
Tan, R.2
-
13
-
-
0030035749
-
In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta
-
Aplin, A. E., Gibb, G. M., Jacobsen, J. S., Gallo, J. M. and Anderton, B. H.: In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta. J. Neurochem. 67(2): 699-707, 1996.
-
(1996)
J. Neurochem.
, vol.67
, Issue.2
, pp. 699-707
-
-
Aplin, A.E.1
Gibb, G.M.2
Jacobsen, J.S.3
Gallo, J.M.4
Anderton, B.H.5
-
14
-
-
0030974795
-
Developmental and aging changes in the expression of amyloid precursor protein in Down syndrome brains
-
Arai, Y., Suzuki, A., Mizuguchi, M. and Takashima, S.: Developmental and aging changes in the expression of amyloid precursor protein in Down syndrome brains. Brain Dev. 19(4): 290-294, 1997.
-
(1997)
Brain Dev.
, vol.19
, Issue.4
, pp. 290-294
-
-
Arai, Y.1
Suzuki, A.2
Mizuguchi, M.3
Takashima, S.4
-
15
-
-
0035146717
-
Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy
-
Arai, T., Ikeda, K., Akiyama, H., Shikamoto, Y., Tsuchiya, K., Yagishita, S., Beach, T., Rogers, J., Schwab, C. and McGeer, P. L.: Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy. Acta Neuro pathol. (Berl.) 101(2): 167-173, 2001.
-
(2001)
Acta Neuro Pathol. (Berl.)
, vol.101
, Issue.2
, pp. 167-173
-
-
Arai, T.1
Ikeda, K.2
Akiyama, H.3
Shikamoto, Y.4
Tsuchiya, K.5
Yagishita, S.6
Beach, T.7
Rogers, J.8
Schwab, C.9
McGeer, P.L.10
-
16
-
-
18744371544
-
The levels of mature glycosylated nicastrin are regulated and correlate with gamma-secretase processing of amyloid betaprecursor protein
-
Arawaka, S., Hasegawa, H., Tandon, A., Janus, C., Chen, F., Yu, G., Kikuchi, K., Koyama, S., Kato, T., Fraser, P. E. and St. George-Hyslop, P.: The levels of mature glycosylated nicastrin are regulated and correlate with gamma-secretase processing of amyloid betaprecursor protein. J. Neurochem. 83(5): 1065-1071, 2002.
-
(2002)
J. Neurochem.
, vol.83
, Issue.5
, pp. 1065-1071
-
-
Arawaka, S.1
Hasegawa, H.2
Tandon, A.3
Janus, C.4
Chen, F.5
Yu, G.6
Kikuchi, K.7
Koyama, S.8
Kato, T.9
Fraser, P.E.10
George-Hyslop, P.11
-
17
-
-
0035830686
-
Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
-
Arendash, G. W., King, D. L., Gordon, M. N., Morgan, D., Hatcher, J. M., Hope, C. L. and Diamond, D. M.: Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. Brain Res. 891: 42-53, 2001.
-
(2001)
Brain Res.
, vol.891
, pp. 42-53
-
-
Arendash, G.W.1
King, D.L.2
Gordon, M.N.3
Morgan, D.4
Hatcher, J.M.5
Hope, C.L.6
Diamond, D.M.7
-
19
-
-
84920031348
-
Galantamine prevents apoptosis induced by betaamyloid and thapsigargin: Involvement of nicotine acetylcholine receptors
-
Arias, E., Ales, E., Gabilan, N. H., Cano-Abad, M. F., Villarroya, M., Garcia, A. G. and Lopez, M. G.: Galantamine prevents apoptosis induced by betaamyloid and thapsigargin: Involvement of nicotine acetylcholine receptors. J. Pharmacol. Exper. Therap. 310: 387-994, 2004.
-
(2004)
J. Pharmacol. Exper. Therap.
, vol.310
, pp. 387-994
-
-
Arias, E.1
Ales, E.2
Gabilan, N.H.3
Cano-Abad, M.F.4
Villarroya, M.5
Garcia, A.G.6
Lopez, M.G.7
-
20
-
-
84919975005
-
Unequal protection afforded by the acetylcholinesterase inhibitors galantamine, donepezil and rivastigmine: Role of nicotinic receptors of SH-SY5H neuroblastoma cells
-
Arias, E., Gallego-Sandin, S., Villarroya, M., Garcia, A. G. and Lopez, M. G.: Unequal protection afforded by the acetylcholinesterase inhibitors galantamine, donepezil and rivastigmine: Role of nicotinic receptors of SH-SY5H neuroblastoma cells. J. Phamacol. Exper. Therap. 311, 2005.
-
J. Phamacol. Exper. Therap.
, vol.311
, pp. 2005
-
-
Arias, E.1
Gallego-Sandin, S.2
Villarroya, M.3
Garcia, A.G.4
Lopez, M.G.5
-
21
-
-
0022649468
-
Neurotrophic factor for central cholinergic neurons is present in both normal and Alzheimer brain tissue
-
Atterwill, C. K. and Bowen, D. M.: Neurotrophic factor for central cholinergic neurons is present in both normal and Alzheimer brain tissue. Acta Neuropthol. (Berlin) 69: 341-342, 1986.
-
(1986)
Acta Neuropthol. (Berlin)
, vol.69
, pp. 341-342
-
-
Atterwill, C.K.1
Bowen, D.M.2
-
22
-
-
0037436022
-
Cerebral hemorrhage and amyloid-beta
-
Atwood, C. S., Perry, G., Smith, M. A.: Cerebral hemorrhage and amyloid-beta. Science 299(5609): 1014, 2003.
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1014
-
-
Atwood, C.S.1
Perry, G.2
Smith, M.A.3
-
23
-
-
0002503154
-
Beta-amyloid peptides as direct cholinergic neuromodulators: A missing link?
-
Auld, D. S., Kar, S. and Quirion, R.: Beta-amyloid peptides as direct cholinergic neuromodulators: A missing link? TINS 21: 43-49, 1998.
-
(1998)
TINS
, vol.21
, pp. 43-49
-
-
Auld, D.S.1
Kar, S.2
Quirion, R.3
-
24
-
-
0038240645
-
Short-term beta-amyloid vaccinations do not improve cognitive performance in cognitively impaired APP + PS1 mice
-
Austin, L., Arendash, G. W., Gordon, M. N., Diamond, D. M., DiCarlo, G., Dickey, C., Ugen, K. and Morgan, D.: Short-term beta-amyloid vaccinations do not improve cognitive performance in cognitively impaired APP + PS1 mice. Behav. Neurosci. 117(3): 478-484, 2003.
-
(2003)
Behav. Neurosci.
, vol.117
, Issue.3
, pp. 478-484
-
-
Austin, L.1
Arendash, G.W.2
Gordon, M.N.3
Diamond, D.M.4
DiCarlo, G.5
Dickey, C.6
Ugen, K.7
Morgan, D.8
-
25
-
-
84919959988
-
-
Eds., Wiley-Liss, New York
-
Battistin, L. and Gerstenbrand, F., Eds.: "Aging Brain and Dementia, " Wiley-Liss, New York, 1990.
-
(1990)
Aging Brain and Dementia
-
-
Battistin, L.1
Gerstenbrand, F.2
-
26
-
-
0004734658
-
-
Eds., Birkhauser, Boston
-
Becker, R. and Giacobini, E., Eds.: "Cholinergic Basis for Alzheimer Therapy, " Birkhauser, Boston, 1991.
-
(1991)
Cholinergic Basis for Alzheimer Therapy
-
-
Becker, R.1
Giacobini, E.2
-
27
-
-
16244381448
-
A measure of neurobehavioral functioning after coma. I. Theory, reliability and validity of the disorders of consciousness scale
-
Bender-Pape, T. L., Heinemann, A. W., Kelly, J. P., Giobbie Hurder, A. and Lundgren, S.: A measure of neurobehavioral functioning after coma. I. Theory, reliability and validity of the disorders of consciousness scale. J. Rehabil. Res. Dev., 42: 1-17, 2005.
-
(2005)
J. Rehabil. Res. Dev.
, vol.42
, pp. 1-17
-
-
Bender-Pape, T.L.1
Heinemann, A.W.2
Kelly, J.P.3
Giobbie Hurder, A.4
Lundgren, S.5
-
28
-
-
0038117200
-
Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging
-
Berezovska, O., Ramdya, P., Skoch, J., Wolfe, M. S., Bacskai, B. J. and Hyman, B. T.: Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging. J. Neurosci. 23(11): 4560-4566, 2003.
-
(2003)
J. Neurosci.
, vol.23
, Issue.11
, pp. 4560-4566
-
-
Berezovska, O.1
Ramdya, P.2
Skoch, J.3
Wolfe, M.S.4
Bacskai, B.J.5
Hyman, B.T.6
-
29
-
-
0037029740
-
Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25- Transgenic mice
-
Bian, F., Nath, R., Sobocinski, G., Booher, R. N., Lipinski, W. J., Callahan, M. J., Pack, A., Wang, K. K. and Walker, L. C. Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25- Transgenic mice. J. Comp. Neurol. 446(3): 257-266, 2002.
-
(2002)
J. Comp. Neurol.
, vol.446
, Issue.3
, pp. 257-266
-
-
Bian, F.1
Nath, R.2
Sobocinski, G.3
Booher, R.N.4
Lipinski, W.J.5
Callahan, M.J.6
Pack, A.7
Wang, K.K.8
Walker, L.C.9
-
30
-
-
0003789592
-
-
Liviana Press, Padova
-
Bick, K., Amaducci, L. and Pepeu, G.: "The Early Story of Alzheimer Disease, " Liviana Press, Padova, 1987.
-
(1987)
The Early Story of Alzheimer Disease
-
-
Bick, K.1
Amaducci, L.2
Pepeu, G.3
-
31
-
-
0001035813
-
Zur Kentniss der Alzheimerschen Krankheit
-
Bielschowski, M.: Zur Kentniss der Alzheimerschen Krankheit. J. Psychol. Neurol. 18: 273-292, 1911.
-
(1911)
J. Psychol. Neurol.
, vol.18
, pp. 273-292
-
-
Bielschowski, M.1
-
32
-
-
0031848338
-
Cholesterol homeostasis in human brain: Turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation
-
Bjorkhem, I., Lutjohann, D., Diczfalusy, U., Stahle, L., Ahlborg, G. and Wahren, J.: Cholesterol homeostasis in human brain: Turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. J. Lipid Res. 39(8): 1594-1600, 1998.
-
(1998)
J. Lipid Res.
, vol.39
, Issue.8
, pp. 1594-1600
-
-
Bjorkhem, I.1
Lutjohann, D.2
Diczfalusy, U.3
Stahle, L.4
Ahlborg, G.5
Wahren, J.6
-
33
-
-
20344365107
-
Mild cognitive impairment-no benefit from vitamin E, little from donepezil
-
Blacker, D.: Mild cognitive impairment-no benefit from vitamin E, little from donepezil. N. Engl. J. Med. 352: 2439-2441, 2005.
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 2439-2441
-
-
Blacker, D.1
-
34
-
-
0014313861
-
The association between quantitative measures of dementia and senile changes in the cerebral grey matter of elderly subjects
-
Blessed, G., Tomlison, B. E. and Roth, M.: The association between quantitative measures of dementia and senile changes in the cerebral grey matter of elderly subjects. Brit. J. Psychiatry 114: 797-811, 1968.
-
(1968)
Brit. J. Psychiatry
, vol.114
, pp. 797-811
-
-
Blessed, G.1
Tomlison, B.E.2
Roth, M.3
-
35
-
-
0025304499
-
Bridging the aging-disease dichotomy. I. The amyloidosis model
-
Blumenthal, H. T. and Premachandra, B. N.: Bridging the aging-disease dichotomy. I. The amyloidosis model. Perspect. Biol. Med. 33: 402-420, 1990.
-
(1990)
Perspect. Biol. Med.
, vol.33
, pp. 402-420
-
-
Blumenthal, H.T.1
Premachandra, B.N.2
-
36
-
-
0029671454
-
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
-
Bodovitz, S. and Klein, W. L.: Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J. Biol. Chem.: 271(8): 4436-4440, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.8
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
37
-
-
0037092417
-
Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis
-
Boncristiano, S., Calhoun, M. E., Kelly, P. H., Pfeifer, M., Bondolfi, L., Stalder, M., Phinney, A. L., Abramowski, D., Sturchler-Pierrat, C., Enz, A., Sommer, B., Staufenbiel, M. and Jucker, M.: Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis. J. Neurosci. 22(8): 3234-3243, 2002.
-
(2002)
J. Neurosci.
, vol.22
, Issue.8
, pp. 3234-3243
-
-
Boncristiano, S.1
Calhoun, M.E.2
Kelly, P.H.3
Pfeifer, M.4
Bondolfi, L.5
Stalder, M.6
Phinney, A.L.7
Abramowski, D.8
Sturchler-Pierrat, C.9
Enz, A.10
Sommer, B.11
Staufenbiel, M.12
Jucker, M.13
-
38
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
-
Borchelt, D. R., Thinakaran, G., Eckman, C. B., Lee, M. K., Davenport, F., Ratovitsky, T., Prada, C. M., Kim, G., Seekins, S., Yager, D., Slunt, H. H., Wang, R., Seeger, M., Levey, A. I., Gandy, S. E., Copeland, N. G., Jenkins, N. A., Price, D. L., Younkin, S. G. and Sisodia, S. S.: Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron 17(5): 1005-1013, 1996.
-
(1996)
Neuron
, vol.17
, Issue.5
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Wang, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
39
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt, D. R., Ratovitski, T., van Lare, J., Lee, M. K., Gonzales, V., Jenkins, N. A., Copeland, N. G., Price, D. L. and Sisodia, S. S.: Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19(4): 939-945, 1997.
-
(1997)
Neuron
, vol.19
, Issue.4
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
40
-
-
0029932417
-
Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties
-
Bouillot, C., Prochiantz, A., Rougon, G. and Allinquant, B.: Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties. J. Biol. Chem. 271(13): 7640-7644, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.13
, pp. 7640-7644
-
-
Bouillot, C.1
Prochiantz, A.2
Rougon, G.3
Allinquant, B.4
-
41
-
-
0017133142
-
Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies
-
Bowen, D. M., Smith, C. B., White, P. and Davison, A. N.: Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies. Brain 49: 459-495, 1976.
-
(1976)
Brain
, vol.49
, pp. 459-495
-
-
Bowen, D.M.1
Smith, C.B.2
White, P.3
Davison, A.N.4
-
43
-
-
0035224478
-
Neurofibrillary tangles and tau phosphorylation
-
Brion, J. P., Anderton, B. H., Authelet, M., Dayanandan, R., Leroy, K., Lovestone, S., Octave, J. N., Pradier, L., Touchet, N. and Tremp, G.: Neurofibrillary tangles and tau phosphorylation. Biochem. Soc. Symp. 2001(67): 81-88, 2001.
-
(2001)
Biochem. Soc. Symp.
, vol.2001
, Issue.67
, pp. 81-88
-
-
Brion, J.P.1
Anderton, B.H.2
Authelet, M.3
Dayanandan, R.4
Leroy, K.5
Lovestone, S.6
Octave, J.N.7
Pradier, L.8
Touchet, N.9
Tremp, G.10
-
44
-
-
0032539989
-
Phosphorylation of the cAMP response element binding protein CREB by cAMP-dependent protein kinase A and glycogen synthase kinase-3 alters DNA-binding affinity, conformation, and increases net charge
-
Bullock, B. P. and Habener, J. F.: Phosphorylation of the cAMP response element binding protein CREB by cAMP-dependent protein kinase A and glycogen synthase kinase-3 alters DNA-binding affinity, conformation, and increases net charge. Biochemistry 37(11): 3795-3809, 1998.
-
(1998)
Biochemistry
, vol.37
, Issue.11
, pp. 3795-3809
-
-
Bullock, B.P.1
Habener, J.F.2
-
45
-
-
0141836978
-
Current treatment of dementia with Lewy bodies and dementia associated with Parkinson's disease
-
Burn, D. J. and McKeith, I. G.: Current treatment of dementia with Lewy bodies and dementia associated with Parkinson's disease. Mov. Disord. 18, Supplt. 6: 872-879, 2003.
-
(2003)
Mov. Disord.
, vol.18
, pp. 872-879
-
-
Burn, D.J.1
McKeith, I.G.2
-
46
-
-
0037386086
-
The metallobiology of Alzheimer's disease
-
Bush, A. I.: The metallobiology of Alzheimer's disease. Trends Neurosci. 26: 207-214, 2003.
-
(2003)
Trends Neurosci.
, vol.26
, pp. 207-214
-
-
Bush, A.I.1
-
47
-
-
0024386288
-
Neurotrophic agents may exacerbate the pathologic cascade of Alzheimer's disease
-
Butcher, L. L. and Woolf, N. J.: Neurotrophic agents may exacerbate the pathologic cascade of Alzheimer's disease. Neurobiol. Aging 10: 557-570, 1989.
-
(1989)
Neurobiol. Aging
, vol.10
, pp. 557-570
-
-
Butcher, L.L.1
Woolf, N.J.2
-
48
-
-
84920034597
-
Animal models of Alzheimer's disease
-
Buxbaum, J. D.: Animal models of Alzheimer's disease. Neurosci. Facts 4: 1, 1993.
-
(1993)
Neurosci. Facts
, vol.4
, pp. 1
-
-
Buxbaum, J.D.1
-
49
-
-
14444272986
-
Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor
-
Buxbaum, J. D., Liu, K. N., Luo, Y., Slack, J. L., Stocking, K. L., Peschon, J. J., Johnson, R. S., Castner, B. J., Cerretti, D. P. and Black, R. A.: Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor. J. Biol. Chem. 273(43): 27765-27767, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.43
, pp. 27765-27767
-
-
Buxbaum, J.D.1
Liu, K.N.2
Luo, Y.3
Slack, J.L.4
Stocking, K.L.5
Peschon, J.J.6
Johnson, R.S.7
Castner, B.J.8
Cerretti, D.P.9
Black, R.A.10
-
50
-
-
0035112647
-
BACE1 is the major beta-secretase for generation of Abeta peptides by neurons
-
Cai, H., Wang, Y., McCarthy, D., Wen, H., Borchelt, D. R., Price, D. L. and Wong, P. C.: BACE1 is the major beta-secretase for generation of Abeta peptides by neurons. Nat. Neurosci. 4(3): 233-234, 2001.
-
(2001)
Nat. Neurosci.
, vol.4
, Issue.3
, pp. 233-234
-
-
Cai, H.1
Wang, Y.2
McCarthy, D.3
Wen, H.4
Borchelt, D.R.5
Price, D.L.6
Wong, P.C.7
-
51
-
-
0027526419
-
Release of excess amyloid beta protein from a mutant amyloid beta protein precursor
-
Cai, X. D., Golde, T. E., Younkin, S. G.: Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science 259(5094): 514-516, 1993.
-
(1993)
Science
, vol.259
, Issue.5094
, pp. 514-516
-
-
Cai, X.D.1
Golde, T.E.2
Younkin, S.G.3
-
52
-
-
0030836345
-
Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: Neuropathologic evidence for a mechanism of increased beta-amyloidogenesis
-
Cataldo, A. M., Barnett, J. L., Pieroni, C. and Nixon, R. A.: Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: Neuropathologic evidence for a mechanism of increased beta-amyloidogenesis. J. Neurosci. 17(16): 6142-6151, 1997.
-
(1997)
J. Neurosci.
, vol.17
, Issue.16
, pp. 6142-6151
-
-
Cataldo, A.M.1
Barnett, J.L.2
Pieroni, C.3
Nixon, R.A.4
-
53
-
-
0344667494
-
Membrane dynamics, cholesterol metabolism and Alzheimer's disease
-
Chauhan, N. B.: Membrane dynamics, cholesterol metabolism and Alzheimer's disease, J. Lipid Res. 44: 2019-2029, 2003.
-
(2003)
J. Lipid Res.
, vol.44
, pp. 2019-2029
-
-
Chauhan, N.B.1
-
54
-
-
0036644989
-
Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody
-
Chauhan, N. B. and Siegel, G. J.: Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody. J. Neurosci. Res. 69(1): 10-23, 2002.
-
(2002)
J. Neurosci. Res.
, vol.69
, Issue.1
, pp. 10-23
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
55
-
-
0037411794
-
Effect of PPF and ALCAR on the induction of NGF- And p75-mRNA and on APP processing in Tg2576 brain
-
Chauhan, N. B. and Siegel, G. J.: Effect of PPF and ALCAR on the induction of NGF- And p75-mRNA and on APP processing in Tg2576 brain. Neurochem. Int. 43(3): 225-233, 2003.
-
(2003)
Neurochem. Int.
, vol.43
, Issue.3
, pp. 225-233
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
56
-
-
13444283725
-
Efficacy of anti-Aβ antibody isotypes used for intracerebroventricular immunization in TgCRND8
-
Chauhan, N. B. and Siegel, G.J.: Efficacy of anti-Aβ antibody isotypes used for intracerebroventricular immunization in TgCRND8. Neurosci. Lett. 375: 143-147, 2005.
-
(2005)
Neurosci. Lett.
, vol.375
, pp. 143-147
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
57
-
-
11144284662
-
Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576
-
Jan
-
Chauhan, N. B., Siegel, G. J. and Feinstein, D. L.: Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576. Neuropharmacology. Jan; 48(1): 93-104, 2005.
-
(2005)
Neuropharmacology
, vol.48
, Issue.1
, pp. 93-104
-
-
Chauhan, N.B.1
Siegel, G.J.2
Feinstein, D.L.3
-
58
-
-
0142102406
-
Aging potentiates Abeta-induced depletion of SNAP-25 in mouse hippocampus
-
Chauhan, N. B., Lichtor, T. and Siegel, G. J.: Aging potentiates Abeta-induced depletion of SNAP-25 in mouse hippocampus. Brain Res. 982(2): 219-227, 2003.
-
(2003)
Brain Res.
, vol.982
, Issue.2
, pp. 219-227
-
-
Chauhan, N.B.1
Lichtor, T.2
Siegel, G.J.3
-
59
-
-
4644308807
-
Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain
-
Chauhan, N. B., Siegel, G. J. and Feinstein, D. L.: Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain. Neurochem. Res. 29: 1897-1911, 2004.
-
(2004)
Neurochem. Res.
, vol.29
, pp. 1897-1911
-
-
Chauhan, N.B.1
Siegel, G.J.2
Feinstein, D.L.3
-
60
-
-
0023729737
-
Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17
-
Cheng, S. V., Nadeau, J. H., Tanzi, R. E., Watkins, P. C., Jagadesh, J., Taylor, B. A., Haines, J. L., Sacchi, N. and Gusella, J. F.: Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17. Proc. Natl. Acad. Sci. U.S.A. 85(16): 6032-6036, 1988.
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, Issue.16
, pp. 6032-6036
-
-
Cheng, S.V.1
Nadeau, J.H.2
Tanzi, R.E.3
Watkins, P.C.4
Jagadesh, J.5
Taylor, B.A.6
Haines, J.L.7
Sacchi, N.8
Gusella, J.F.9
-
61
-
-
0034964390
-
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice
-
Cherny, R. A., Atwood, C. S., Xilinas, M. E., Gray, D. N., Jones, W. D., McLean, C. A., Barnham, K. J., Volitakis, I., Fraser, F. W., Kim, Y., Huang, X., Goldstein, L. E., Moir, R. D., Lim, J. T., Beyreuther, K., Zheng, H., Tanzi, R. E., Masters, C. L. and Bush, A. I.: Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron. 30: 665-676, 2001.
-
(2001)
Neuron.
, vol.30
, pp. 665-676
-
-
Cherny, R.A.1
Atwood, C.S.2
Xilinas, M.E.3
Gray, D.N.4
Jones, W.D.5
McLean, C.A.6
Barnham, K.J.7
Volitakis, I.8
Fraser, F.W.9
Kim, Y.10
Huang, X.11
Goldstein, L.E.12
Moir, R.D.13
Lim, J.T.14
Beyreuther, K.15
Zheng, H.16
Tanzi, R.E.17
Masters, C.L.18
Bush, A.I.19
-
62
-
-
0034742113
-
Amyloid beta-peptide 1-40 increases neuronal membrane fluidity: Role of cholesterol and brain region
-
Chochina, S. V., Avdulov, N. A., Igbavboa, U., Cleary, J. P., O'Hare, E. O. and Wood, W. G.: Amyloid beta-peptide 1-40 increases neuronal membrane fluidity: Role of cholesterol and brain region. J. Lipid Res. 42(8): 1292-1297, 2001.
-
(2001)
J. Lipid Res.
, vol.42
, Issue.8
, pp. 1292-1297
-
-
Chochina, S.V.1
Avdulov, N.A.2
Igbavboa, U.3
Cleary, J.P.4
O'Hare, E.O.5
Wood, W.G.6
-
63
-
-
0035374675
-
Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2
-
Choi, E. K., Zaidi, N. F., Miller, J. S., Crowley, A. C., Merriam, D. E., Lilliehook, C., Buxbaum, J. D. and Wasco, W.: Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2. J. Biol. Chem. 276(22): 19197-19204, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.22
, pp. 19197-19204
-
-
Choi, E.K.1
Zaidi, N.F.2
Miller, J.S.3
Crowley, A.C.4
Merriam, D.E.5
Lilliehook, C.6
Buxbaum, J.D.7
Wasco, W.8
-
64
-
-
0030581107
-
Amyloidogenic processing of Alzheimer's amyloid precursor protein in vitro and its modulation by metal ions and tacrine
-
Chong, Y. H. and Suh, Y. H.: Amyloidogenic processing of Alzheimer's amyloid precursor protein in vitro and its modulation by metal ions and tacrine. Life Sci. 59: 545-557, 1996.
-
(1996)
Life Sci.
, vol.59
, pp. 545-557
-
-
Chong, Y.H.1
Suh, Y.H.2
-
65
-
-
0026745610
-
Mutation of the betaamyloid precursor protein in familial Alzheimer's disease increases beta-protein production
-
Citron, M., Oltersdorf, T., Haass, C., McConlogue, L., Hung, A. Y., Seubert, P., Vigo-Pelfrey, C., Lieberburg, I. and Selkoe, D. J.: Mutation of the betaamyloid precursor protein in familial Alzheimer's disease increases beta-protein production. Nature 360(6405): 672-674, 1992.
-
(1992)
Nature
, vol.360
, Issue.6405
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
66
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice
-
Citron, M., Westaway, D., Xia, W., Carlson, G., Diehl, T., Levesque, G., Johnson-Wood, K., Lee, M., Seubert, P., Davis, A., Kholodenko, D., Motter, R., Sherrington, R., Perry, B., Yao, H., Strome, R., Lieberburg, I., Rommens, J., Kim, S., Schenk, D., Fraser, P., St. George Hyslop, P. and Selkoe, D. J.: Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nat. Med. 3(1):67-72, 1997.
-
(1997)
Nat. Med.
, vol.3
, Issue.1
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
George Hyslop, P.22
Selkoe, D.J.23
more..
-
68
-
-
19944429977
-
Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study
-
Cook, L. J., Ho, L. W., Wang, L., Terrenoir, E., Brayne, C., Evans, J. G., Xuereb, J., Cairns, N. J., Turic, D., Hollingwrth, P., Moore, P. J., Jehu, L., Archer, N., Walter, S., Foy, C., Edmondson, A., Powell, J., Lovestone, S., Williams, J. and Rubinsztein, D. C.: Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study. Am. J. Med. Genet. B Neuropsychiatr. Genet. 132B: 5-8, 2004.
-
(2004)
Am. J. Med. Genet. B Neuropsychiatr. Genet.
, vol.132 B
, pp. 5-8
-
-
Cook, L.J.1
Ho, L.W.2
Wang, L.3
Terrenoir, E.4
Brayne, C.5
Evans, J.G.6
Xuereb, J.7
Cairns, N.J.8
Turic, D.9
Hollingwrth, P.10
Moore, P.J.11
Jehu, L.12
Archer, N.13
Walter, S.14
Foy, C.15
Edmondson, A.16
Powell, J.17
Lovestone, S.18
Williams, J.19
Rubinsztein, D.C.20
more..
-
69
-
-
23244456099
-
A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease
-
Cottrell, B. A., Galvan, V., Banwait, S., Gorostiza, O., et al.: A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease. Ann Neurol. 58: 277-289, 2005.
-
(2005)
Ann Neurol.
, vol.58
, pp. 277-289
-
-
Cottrell, B.A.1
Galvan, V.2
Banwait, S.3
Gorostiza, O.4
-
70
-
-
0036630634
-
Statins in the prevention and treatment of Alzheimer disease
-
Crisby, M., Carlson, L. A. and Winblad, B.: Statins in the prevention and treatment of Alzheimer disease. Alzheimer Dis. Assoc. Disord. 16(3):131-136, 2002.
-
(2002)
Alzheimer Dis. Assoc. Disord.
, vol.16
, Issue.3
, pp. 131-136
-
-
Crisby, M.1
Carlson, L.A.2
Winblad, B.3
-
71
-
-
0035087123
-
Selective smallmolecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death
-
Cross, D. A., Culbert, A. A., Chalmers, K. A., Facci, L., Skaper, S. D. and Reith, A. D.: Selective smallmolecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death. J. Neurochem. 77(1): 94-102, 2001.
-
(2001)
J. Neurochem.
, vol.77
, Issue.1
, pp. 94-102
-
-
Cross, D.A.1
Culbert, A.A.2
Chalmers, K.A.3
Facci, L.4
Skaper, S.D.5
Reith, A.D.6
-
72
-
-
0034602179
-
Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal
-
Crowder, R. J. and Freeman, R. S.: Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal. J. Biol. Chem. 275(44): 34266-34271, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.44
, pp. 34266-34271
-
-
Crowder, R.J.1
Freeman, R.S.2
-
73
-
-
0034965634
-
Efficacy of metrifonate in improving the psychiatric and behavioral disturbances of patients with Alzheimer's disease
-
Cummings, J. L., Nadel, A., Masterman, D. and Cyrus, P. A.: Efficacy of metrifonate in improving the psychiatric and behavioral disturbances of patients with Alzheimer's disease, J. Geriatr. Psychiatry Neurol. 14: 101-108, 2001.
-
(2001)
J. Geriatr. Psychiatry Neurol.
, vol.14
, pp. 101-108
-
-
Cummings, J.L.1
Nadel, A.2
Masterman, D.3
Cyrus, P.A.4
-
74
-
-
0034692686
-
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways
-
D'Amico, M., Hulit, J., Amanatullah, D. F., Zafonte, B. T., Albanese, C., Bouzahzah, B., Fu, M., Augenlicht, L. H., Donehower, L. A., Takemaru, K., Moon, R. T., Davis, R., Lisanti, M. P., Shtutman, M., Zhurinsky, J., Ben-Ze'ev, A., Troussard, A. A., Dedhar, S. and Pestell, R. G.: The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways. J. Biol. Chem. 275(42): 32649-32657, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.42
, pp. 32649-32657
-
-
D'Amico, M.1
Hulit, J.2
Amanatullah, D.F.3
Zafonte, B.T.4
Albanese, C.5
Bouzahzah, B.6
Fu, M.7
Augenlicht, L.H.8
Donehower, L.A.9
Takemaru, K.10
Moon, R.T.11
Davis, R.12
Lisanti, M.P.13
Shtutman, M.14
Zhurinsky, J.15
Ben-Ze'ev, A.16
Troussard, A.A.17
Dedhar, S.18
Pestell, R.G.19
-
75
-
-
84909770612
-
Selective loss of central cholinergic neurons in Alzheimer's disease
-
Davies, P. and Maloney, A. J. F.: Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 2: 1402, 1976.
-
(1976)
Lancet
, vol.2
, pp. 1402
-
-
Davies, P.1
Maloney, A.J.F.2
-
76
-
-
0034704244
-
Transmembrane molecular pump activity of Niemann- Pick C1 protein
-
Davies, J. P., Chen, F. W. and Ioannou, Y. A.: Transmembrane molecular pump activity of Niemann- Pick C1 protein. Science 290: 2295-2298, 2000.
-
(2000)
Science
, vol.290
, pp. 2295-2298
-
-
Davies, J.P.1
Chen, F.W.2
Ioannou, Y.A.3
-
77
-
-
0017031325
-
Physostigmine: Effects on cognition and affect in normal subjects
-
Davis, K. L., Hollister, L. E. and Tinkleberg, J. R.: Physostigmine: Effects on cognition and affect in normal subjects. Psychopharmacology 51: 23-27, 1976.
-
(1976)
Psychopharmacology
, vol.51
, pp. 23-27
-
-
Davis, K.L.1
Hollister, L.E.2
Tinkleberg, J.R.3
-
79
-
-
0037089102
-
APP knockout attenuates microglial activation and enhances neuron survival in substantia nigra compacta after axotomy
-
DeGiorgio, L. A., Shimizu, Y., Chun, H. S., Cho, B. P., Sugama, S., Joh, T. H. and Volpe, B. T.: APP knockout attenuates microglial activation and enhances neuron survival in substantia nigra compacta after axotomy. Glia. 38(2): 174-178, 2002.
-
(2002)
Glia.
, vol.38
, Issue.2
, pp. 174-178
-
-
DeGiorgio, L.A.1
Shimizu, Y.2
Chun, H.S.3
Cho, B.P.4
Sugama, S.5
Joh, T.H.6
Volpe, B.T.7
-
80
-
-
0035421638
-
Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability
-
De Jonghe, C., Esselens, C., Kumar-Singh, S., Craessaerts, K., Serneels, S., Checler, F., Annaert, W., Van Broeckhoven, C. and De Strooper, B.: Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability. Hum. Mol. Genet. 10(16): 1665-1671, 2001.
-
(2001)
Hum. Mol. Genet.
, vol.10
, Issue.16
, pp. 1665-1671
-
-
De Jonghe, C.1
Esselens, C.2
Kumar-Singh, S.3
Craessaerts, K.4
Serneels, S.5
Checler, F.6
Annaert, W.7
Van Broeckhoven, C.8
De Strooper, B.9
-
81
-
-
0038752964
-
Pathology and pathways of Alzheimer's disease with an update on new developments in treatment
-
Supplt. Dementia
-
DeKosky, S. T.: Pathology and pathways of Alzheimer's disease with an update on new developments in treatment. J. Am. Geriatr. Soc. 51(5), Supplt. Dementia: S314-S320, 2003.
-
(2003)
J. Am. Geriatr. Soc.
, vol.51
, Issue.5
, pp. S314-S320
-
-
DeKosky, S.T.1
-
82
-
-
0035083555
-
Cholesterol metabolism in the brain
-
Dietschy, J. M. and Turley, S. D.: Cholesterol metabolism in the brain. Curr. Opin. Lipidol. 12(2): 105- 112, 2001.
-
(2001)
Curr. Opin. Lipidol.
, vol.12
, Issue.2
, pp. 105-112
-
-
Dietschy, J.M.1
Turley, S.D.2
-
83
-
-
0037151046
-
Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice coexpressing mutant human presenilin 1 and amyloid precursor proteins
-
Dineley, K. T., Xia, X., Bui, D., Sweatt, J. D. and Zheng, H.: Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice coexpressing mutant human presenilin 1 and amyloid precursor proteins. J. Biol. Chem. 277(25): 22768- 22780, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.25
, pp. 22768-22780
-
-
Dineley, K.T.1
Xia, X.2
Bui, D.3
Sweatt, J.D.4
Zheng, H.5
-
84
-
-
33645504715
-
De la nature de l'alteration fibrillaire d'Alzheimer
-
Divry, P.: De la nature de l'alteration fibrillaire d'Alzheimer. J. Belge Neurol. Psychiat. 34: 197-201, 1934.
-
(1934)
J. Belge Neurol. Psychiat.
, vol.34
, pp. 197-201
-
-
Divry, P.1
-
85
-
-
0037383322
-
GSK-3: Tricks of the trade for a multi-tasking kinase
-
Doble, B. W. and Woodgett, J. R.: GSK-3: Tricks of the trade for a multi-tasking kinase. J. Cell Sci. 116:1175- 1186, 2003.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
86
-
-
24744449320
-
Phenotypic and biochemical analyses of BACE1- And BACE2-deficient mice
-
Dominguez, D., Tournoy, J., Hartmann, D., Huth, T., Cryus, K., Deforce, S., Serneels, L., Camacho, I. E., Marjauy, E., Craessaerts, K., Roebroek, A. J., Schwake, M., D'Hooge, R., Back, P., Kalinke, U., Moechars, D., Alzheimer, C., Reiss, K., Saftig, P. and De Strooper, B.: Phenotypic and biochemical analyses of BACE1- And BACE2-deficient mice. J. Biol. Chem. 280: 30797-30806, 2005.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 30797-30806
-
-
Dominguez, D.1
Tournoy, J.2
Hartmann, D.3
Huth, T.4
Cryus, K.5
Deforce, S.6
Serneels, L.7
Camacho, I.E.8
Marjauy, E.9
Craessaerts, K.10
Roebroek, A.J.11
Schwake, M.12
D'Hooge, R.13
Back, P.14
Kalinke, U.15
Moechars, D.16
Alzheimer, C.17
Reiss, K.18
Saftig, P.19
De Strooper, B.20
more..
-
87
-
-
0002633972
-
Central cholinergic system and memory
-
M. A. Lipton, A. DiMascio, and K. F. Killam, Eds., Raven Press, New York
-
Drachman, D. A.: Central cholinergic system and memory. In: "Psychopharmacology: A Generation of Progress, " M. A. Lipton, A. DiMascio, and K. F. Killam, Eds., pp. 651-662, Raven Press, New York, 1978.
-
(1978)
Psychopharmacology: A Generation of Progress
, pp. 651-662
-
-
Drachman, D.A.1
-
88
-
-
0015965912
-
Human memory and the cholinergic system-A relationship to aging?
-
Drachman, D. A. and Leavitt, J.: Human memory and the cholinergic system-a relationship to aging? Arch. Neurol. Psychiat. 30: 113-121, 1974.
-
(1974)
Arch. Neurol. Psychiat.
, vol.30
, pp. 113-121
-
-
Drachman, D.A.1
Leavitt, J.2
-
89
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
-
Duff, K., Eckman, C., Zehr, C., Yu, X., Prada, C. M., Perez-tur, J., Hutton, M., Buee, L., Harigaya, Y., Yager, D., Morgan, D., Gordon, M. N., Holcomb, L., Refolo, L., Zenk, B., Hardy, J. and Younkin, S.: Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature 383(6602): 710-713, 1996.
-
(1996)
Nature
, vol.383
, Issue.6602
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
90
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts
-
Ehehalt, R., Keller, P., Haass, C., Thiele, C. and Simons, K.: Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J. Cell Biol. 160(1): 113-123, 2003.
-
(2003)
J. Cell Biol.
, vol.160
, Issue.1
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
91
-
-
85047691727
-
NSAIDs and enantiomers of flurbiprofen target gammasecretase and lower Abeta 42 in vivo
-
Eriksen, J. L., Sagi, S. A., Smith, T. E., Weggen, S., Das, P., McLendon, D. C., Ozols, V. V., Jessing, K. W., Zavitz, K. H., Koo, E. H. and Golde, T. E.: NSAIDs and enantiomers of flurbiprofen target gammasecretase and lower Abeta 42 in vivo. J. Clin. Invest. 112(3): 440-449, 2003.
-
(2003)
J. Clin. Invest.
, vol.112
, Issue.3
, pp. 440-449
-
-
Eriksen, J.L.1
Sagi, S.A.2
Smith, T.E.3
Weggen, S.4
Das, P.5
McLendon, D.C.6
Ozols, V.V.7
Jessing, K.W.8
Zavitz, K.H.9
Koo, E.H.10
Golde, T.E.11
-
92
-
-
0027429837
-
Brain selective inhibition of acetylcholinesterase: A novel approach to therapy for Alzheimer's disease
-
A. C. Cuello, Ed., Elsevier, Amsterdam
-
Enz, A., Amstutz, R., Bodekke, H., Gmelin, G. and Malanowski, J.: Brain selective inhibition of acetylcholinesterase: A novel approach to therapy for Alzheimer's disease. In: "Cholinergic Function and Dysfunction, " A. C. Cuello, Ed., pp. 431-438, Elsevier, Amsterdam, 1993.
-
(1993)
Cholinergic Function and Dysfunction
, pp. 431-438
-
-
Enz, A.1
Amstutz, R.2
Bodekke, H.3
Gmelin, G.4
Malanowski, J.5
-
93
-
-
0037022644
-
Activity- dependent isolation of the presenilin- gammasecretase complex reveals nicastrin and a gamma substrate
-
Esler, W. P., Kimberly, W. T., Ostaszewski, B. L., Ye, W., Diehl, T. S., Selkoe, D. J., Wolfe, M. S.: Activity- dependent isolation of the presenilin- gammasecretase complex reveals nicastrin and a gamma substrate. Proc. Natl. Acad. Sci. U.S.A. 99(5): 2720- 2725, 2002.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, Issue.5
, pp. 2720-2725
-
-
Esler, W.P.1
Kimberly, W.T.2
Ostaszewski, B.L.3
Ye, W.4
Diehl, T.S.5
Selkoe, D.J.6
Wolfe, M.S.7
-
94
-
-
0038375640
-
Effect of nonsteroidal anti-inflammatory drugs on risk of Alzheimer's disease: Systematic review and metaanalysis of observational studies
-
Etminan, M., Gill, S. and Samii, A.: Effect of nonsteroidal anti-inflammatory drugs on risk of Alzheimer's disease: Systematic review and metaanalysis of observational studies. BMJ 327(7407): 128, 2003.
-
(2003)
BMJ
, vol.327
, Issue.7407
, pp. 128
-
-
Etminan, M.1
Gill, S.2
Samii, A.3
-
95
-
-
0002043699
-
Ageing and disease
-
D. Evered and J. Whalen, Eds. Ciba Found. Symp. No. 124, Wiley, Chichester
-
Evans, J. G.: Ageing and disease. In: "Research and the Ageing Population, " D. Evered and J. Whalen, Eds., Ciba Found. Symp. No. 124, Wiley, Chichester, 1988.
-
(1988)
Research and the Ageing Population
-
-
Evans, J.G.1
-
96
-
-
0036233168
-
Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease
-
Fagan, A. M., Watson, M., Parsadanian, M., Bales, K. R., Paul, S. M. and Holtzman, D. M.: Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease. Neurobiol. Dis. 9(3): 305- 318, 2002.
-
(2002)
Neurobiol. Dis.
, vol.9
, Issue.3
, pp. 305-318
-
-
Fagan, A.M.1
Watson, M.2
Parsadanian, M.3
Bales, K.R.4
Paul, S.M.5
Holtzman, D.M.6
-
97
-
-
0041589436
-
Partial purification and characterization of ?-secretase from post-mortem human brain
-
Farmery, M. R., Tjernberg, L. O., Pursglove, S. E., Bergman, A., et al.: Partial purification and characterization of ?-secretase from post-mortem human brain. J. Biol. Chem. 278: 24277-24284, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 24277-24284
-
-
Farmery, M.R.1
Tjernberg, L.O.2
Pursglove, S.E.3
Bergman, A.4
-
98
-
-
0001504829
-
Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo
-
Fassbender, K., Simons, M., Bergmann, C., Stroick, M., Lutjohann, D., Keller, P., Runz, H., Kuhl, S., Bertsch, T., von Bergmann, K., Hennerici, M., Beyreuther, K. and Hartmann, T.: Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo. Proc. Natl. Acad. Sci. U.S.A. 98(10): 5856-5861, 2001.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, Issue.10
, pp. 5856-5861
-
-
Fassbender, K.1
Simons, M.2
Bergmann, C.3
Stroick, M.4
Lutjohann, D.5
Keller, P.6
Runz, H.7
Kuhl, S.8
Bertsch, T.9
Von Bergmann, K.10
Hennerici, M.11
Beyreuther, K.12
Hartmann, T.13
-
99
-
-
0036942843
-
Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration
-
Ferrer, I., Barrachina, M. and Puig, B.: Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Acta Neuropathol (Berl.) 104(6): 583-591, 2002.
-
(2002)
Acta Neuropathol (Berl.)
, vol.104
, Issue.6
, pp. 583-591
-
-
Ferrer, I.1
Barrachina, M.2
Puig, B.3
-
100
-
-
0037246583
-
Phosphorylated protein kinases associated with neuronal and glial tau deposits in argyrophilic brain disease
-
Ferrer, I., Barrachina, M., Tolnay, M., Rey, M. J., Vidal, N., Carmona, M., Blanco, R. and Puig, B.: Phosphorylated protein kinases associated with neuronal and glial tau deposits in argyrophilic brain disease. Brain Pathol. 13(1): 62-78, 2003a.
-
(2003)
Brain Pathol.
, vol.13
, Issue.1
, pp. 62-78
-
-
Ferrer, I.1
Barrachina, M.2
Tolnay, M.3
Rey, M.J.4
Vidal, N.5
Carmona, M.6
Blanco, R.7
Puig, B.8
-
101
-
-
0037327535
-
Tau phosphorylation and kinase activation in familial tauopathy linked to deln296 mutation
-
Ferrer, I., Pastor, P., Rey, M. J., Munoz, E., Puig, B., Pastor, E., Oliva, R. and Tolosa, E.: Tau phosphorylation and kinase activation in familial tauopathy linked to deln296 mutation. Neuropathol. Appl. Neuro biol. 29(1): 23-34, 2003b.
-
(2003)
Neuropathol. Appl. Neuro Biol.
, vol.29
, Issue.1
, pp. 23-34
-
-
Ferrer, I.1
Pastor, P.2
Rey, M.J.3
Munoz, E.4
Puig, B.5
Pastor, E.6
Oliva, R.7
Tolosa, E.8
-
102
-
-
0002447758
-
Biochemistry of aging
-
Sixth Edition, G. J. Siegel, B. W. Agranoff, R. W. Albers, S. K. Fisher, and M. D. Uhler, Eds., Philadelphia: Lippincott-Raven
-
Finch, C. E. and Roth, G. S.: Biochemistry of Aging. In: "Basic Neurochemistry", Sixth Edition, G. J. Siegel, B. W. Agranoff, R. W. Albers, S. K. Fisher, and M. D. Uhler, Eds., pp. 614-633, Philadelphia: Lippincott- Raven, 1999.
-
(1999)
Basic Neurochemistry
, pp. 614-633
-
-
Finch, C.E.1
Roth, G.S.2
-
103
-
-
0028670773
-
A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression
-
Fiol, C. J., Williams, J. S., Chou, C. H., Wang, Q. M., Roach, P. J. and Andrisani, O. M.: A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression. J. Biol. Chem. 269(51): 32187- 32193, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, Issue.51
, pp. 32187-32193
-
-
Fiol, C.J.1
Williams, J.S.2
Chou, C.H.3
Wang, Q.M.4
Roach, P.J.5
Andrisani, O.M.6
-
104
-
-
0001361276
-
Miliary Nekrosen mit drueszinger Wucherungen der Neurofibrillen, eine regelmaessige Veraenderung der Hirnrinde bei seniler Demenz
-
Fischer, O.: Miliary Nekrosen mit drueszinger Wucherungen der Neurofibrillen, eine regelmaessige Veraenderung der Hirnrinde bei seniler Demenz. Monatsschrft. Psych. U. Neurol. 22: 361- 372, 1907.
-
(1907)
Monatsschrft. Psych. U. Neurol.
, vol.22
, pp. 361-372
-
-
Fischer, O.1
-
105
-
-
0030764026
-
Muscarinic agonists for the treatment of Alzheimer's disease: Progress and perspectives
-
Fisher, A.: Muscarinic agonists for the treatment of Alzheimer's disease: Progress and perspectives. Eur. Opin. Invest. Drugs 6: 1395-1411, 1997.
-
(1997)
Eur. Opin. Invest. Drugs
, vol.6
, pp. 1395-1411
-
-
Fisher, A.1
-
106
-
-
84920048757
-
Novel m1 muscarinic agonists in treatment and delaying the progression of Alzheimer's disease: An unifying hypothesis
-
J. Massoulié, Ed., Elsevier, Amsterdam
-
Fisher, A., Brandeis, R., Haring, R., Eshar, N., Heldman, E., Karton, Y., Eisenberg, O., Meshulam, H., Marciano, D., Bar-Ner, N. and Pittel, Z.: Novel m1 muscarinic agonists in treatment and delaying the progression of Alzheimer's disease: An unifying hypothesis. In: "From Torpedo Electric Organ to Human Brain: Fundamental and Applied Aspects, " J. Massoulié, Ed., pp. 227-340, Elsevier, Amsterdam, 1998.
-
(1998)
From Torpedo Electric Organ to Human Brain: Fundamental and Applied Aspects
, pp. 227-340
-
-
Fisher, A.1
Brandeis, R.2
Haring, R.3
Eshar, N.4
Heldman, E.5
Karton, Y.6
Eisenberg, O.7
Meshulam, H.8
Marciano, D.9
Bar-Ner, N.10
Pittel, Z.11
-
107
-
-
0034528416
-
M1 muscarinic agonists as potential disease-modifying agents in Alzheimer's disease. Rationale and perspectives
-
Fisher, A., Michaelson, D. M., Brandeis, R., Haring, R., Chapman, S. and Pittel, Z.: M1 muscarinic agonists as potential disease-modifying agents in Alzheimer's disease. Rationale and perspectives. Ann. N. Y. Acad. Sci. 920: 315-320, 2000.
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.920
, pp. 315-320
-
-
Fisher, A.1
Michaelson, D.M.2
Brandeis, R.3
Haring, R.4
Chapman, S.5
Pittel, Z.6
-
108
-
-
84919975004
-
-
Eds., Alpha Academic Press, London
-
Foerstl, H. and Levy, R., Eds.: Introduction to Alzheimer's paper "On certain diseases of Old Age, " Alpha Academic Press, London, 2: 71-73, 1991.
-
(1991)
Introduction to Alzheimer's Paper "On Certain Diseases of Old Age
, vol.2
, pp. 71-73
-
-
Foerstl, H.1
Levy, R.2
-
109
-
-
0033781487
-
Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons
-
Forlenza, O. V., Spink, J. M., Dayanandan, R., Anderton, B. H., Olesen, O. F. and Lovestone, S.: Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons. J. Neural. Transm. 107(10): 1201-1212, 2000.
-
(2000)
J. Neural. Transm.
, vol.107
, Issue.10
, pp. 1201-1212
-
-
Forlenza, O.V.1
Spink, J.M.2
Dayanandan, R.3
Anderton, B.H.4
Olesen, O.F.5
Lovestone, S.6
-
110
-
-
0038004636
-
Clinical biomarkers in drug discovery and development
-
Frank, R. and Hargreaves, R.: Clinical biomarkers in drug discovery and development. Nat. Rev. Drug Discov. 2(7): 566-580, 2003.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, Issue.7
, pp. 566-580
-
-
Frank, R.1
Hargreaves, R.2
-
111
-
-
0035232145
-
Presenilin function: Connections to Alzheimer's disease and signal transduction
-
Fraser, P. E., Yu, G., Levesque, L., Nishimura, M., Yang, D. S., Mount, H. T., Westaway, D. and St. George Hyslop, P. H.: Presenilin function: Connections to Alzheimer's disease and signal transduction. Biochem. Soc. Symp. 2001(67): 89-100, 2001.
-
(2001)
Biochem. Soc. Symp.
, vol.2001
, Issue.67
, pp. 89-100
-
-
Fraser, P.E.1
Yu, G.2
Levesque, L.3
Nishimura, M.4
Yang, D.S.5
Mount, H.T.6
Westaway, D.7
George Hyslop, P.H.8
-
112
-
-
0033519601
-
The role of cholesterol in the biosynthesis of beta-amyloid
-
Frears, E. R., Stephens, D. J., Walters, C. E., Davies, H. and Austen, B. M.: The role of cholesterol in the biosynthesis of beta-amyloid. Neuroreport 10(8): 1699-1705, 1999.
-
(1999)
Neuroreport
, vol.10
, Issue.8
, pp. 1699-1705
-
-
Frears, E.R.1
Stephens, D.J.2
Walters, C.E.3
Davies, H.4
Austen, B.M.5
-
113
-
-
0346103816
-
Quantification of nicotinic acetylcholine receptors in human brain using [1231]5-I-A-85380 SPET
-
Fujita, M., Ichise, M., van Dyck, C. H., Zoghbi, S. S., Tamagnan, G., Mukhin, A. G., Bozkurt, A., Seneca, N., Tipre, D., DeNucci, C. C., Iida, H., Vaupel, D. B., Horti, A. G., Koren, A. O., Kimes, A. S., London, E. D., Seibyl, j. P., Baldwin, R. M. and Innis, R. B.: Quantification of nicotinic acetylcholine receptors in human brain using [1231]5-I-A-85380 SPET. Eur. J. Nucl. Med. Mol. Imaging 30: 1620-1619, 2003.
-
(2003)
Eur. J. Nucl. Med. Mol. Imaging
, vol.30
, pp. 1619-1620
-
-
Fujita, M.1
Ichise, M.2
Van Dyck, C.H.3
Zoghbi, S.S.4
Tamagnan, G.5
Mukhin, A.G.6
Bozkurt, A.7
Seneca, N.8
Tipre, D.9
DeNucci, C.C.10
Iida, H.11
Vaupel, D.B.12
Horti, A.G.13
Koren, A.O.14
Kimes, A.S.15
London, E.D.16
Seibyl, J.P.17
Baldwin, R.M.18
Innis, R.B.19
-
114
-
-
18044372996
-
Neuroprotective effect of donepezil, a nicotinic acetylcholine receptor activator, on cerebral infarction in rats
-
Fujiki, M., Kobayashi, H., Uchida, S., Inoue, R. and Ishii, K.: Neuroprotective effect of donepezil, a nicotinic acetylcholine receptor activator, on cerebral infarction in rats. Brain Res. 1043: 2236-2241, 2005.
-
(2005)
Brain Res.
, vol.1043
, pp. 2236-2241
-
-
Fujiki, M.1
Kobayashi, H.2
Uchida, S.3
Inoue, R.4
Ishii, K.5
-
115
-
-
0041689948
-
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
Gamblin, T. C., Chen, F., Zambrano, A., Abraha, A., Lagalwar, S., Guillozet, A. L., Lu, M., Fu, Y., Garcia-Sierra, F., LaPointe, N., Miller, R., Berry, R. W., Binder, L. I. and Cryns, V. L.: Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 100(17): 10032-10037, 2003.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, Issue.17
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
LaPointe, N.10
Miller, R.11
Berry, R.W.12
Binder, L.I.13
Cryns, V.L.14
-
116
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games, D., Adams, D., Alessandrini, R., Barbour, R., Berthelette, P., Blackwell, C., Carr, T., Clemens, J., Donaldson, T., Gillespie, F., et al.: Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 373(6514): 523-527, 1995.
-
(1995)
Nature
, vol.373
, Issue.6514
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
-
117
-
-
0038732558
-
Estrogen and neurodegeneration
-
Gandy, S.: Estrogen and neurodegeneration. Neurochem. Res. 28(7): 1003-1008, 2003.
-
(2003)
Neurochem. Res.
, vol.28
, Issue.7
, pp. 1003-1008
-
-
Gandy, S.1
-
118
-
-
12144290846
-
Alzheimer Aa vaccination of Rhesus monkeys (Macaca Mulatta)
-
Gandy, S., DeMattos, R. B., Lemere, C. A., Heppner, F. L., Leerone, J., Aguzzi, A., Ershler, W. B., Dai, J., Fraser, P., St. George-Hyslop, P., Holtzman, D. M., Walker, L. C. and Keller, E. T.: Alzheimer Aa vaccination of Rhesus monkeys (Macaca Mulatta). Alzheimer Dis. Assoc. Disord. 303: 44-46, 2004.
-
(2004)
Alzheimer Dis. Assoc. Disord.
, vol.303
, pp. 44-46
-
-
Gandy, S.1
DeMattos, R.B.2
Lemere, C.A.3
Heppner, F.L.4
Leerone, J.5
Aguzzi, A.6
Ershler, W.B.7
Dai, J.8
Fraser, P.9
George-Hyslop, P.10
Holtzman, D.M.11
Walker, L.C.12
Keller, E.T.13
-
119
-
-
0036884291
-
Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway
-
Garrido, J. L., Godoy, J. A., Alvarez, A., Bronfman, M. and Inestrosa, N. C.: Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway. FASEB J. 16(14): 1982-1984, 2002.
-
(2002)
FASEB J.
, vol.16
, Issue.14
, pp. 1982-1984
-
-
Garrido, J.L.1
Godoy, J.A.2
Alvarez, A.3
Bronfman, M.4
Inestrosa, N.C.5
-
120
-
-
0037443604
-
Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation
-
Ghribi, O., Herman, M. M. and Savory, J.: Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation. J. Neurosci. Res. 71(6): 853-862, 2003.
-
(2003)
J. Neurosci. Res.
, vol.71
, Issue.6
, pp. 853-862
-
-
Ghribi, O.1
Herman, M.M.2
Savory, J.3
-
121
-
-
0025644484
-
Cholinergic receptors in human brain: Effects of aging and Alzheimer's disease
-
Giacobini, E.: Cholinergic receptors in human brain: Effects of aging and Alzheimer's disease. J. Neurosci. Res. 27: 548-560, 1990.
-
(1990)
J. Neurosci. Res.
, vol.27
, pp. 548-560
-
-
Giacobini, E.1
-
122
-
-
0002654491
-
The second generation of cholinesterase inhibitors: Pharmacological aspects
-
R. Becker and E. Giacobini, Birkhaeuser, Boston
-
Giacobini, E.: The second generation of cholinesterase inhibitors: Pharmacological aspects. In: "Cholinergic Basis for Alzheimer Therapy, " R. Becker and E. Giacobini, pp. 247-296, Birkhaeuser, Boston, 1991.
-
(1991)
Cholinergic Basis for Alzheimer Therapy
, pp. 247-296
-
-
Giacobini, E.1
-
123
-
-
0001885399
-
Cholinesterase inhibitors: From the Calabar bean to Alzheimer therapy
-
E. Giacobini, Ed., Martin Dunitz, London
-
Giacobini, E.: Cholinesterase inhibitors: from the Calabar bean to Alzheimer therapy. In: "Cholinesterases and Cholinesterase Inhibitors, " E. Giacobini, Ed. pp. 181-226, Martin Dunitz, London, 2000.
-
(2000)
Cholinesterases and Cholinesterase Inhibitors
, pp. 181-226
-
-
Giacobini, E.1
-
125
-
-
0141818332
-
Cholinergic function and Alzheimer's disease
-
Giacobini, E.: Cholinergic function and Alzheimer's disease. Int. J. Geriatr. Psychiatry 18, Supplt. 1: S1-S5, 2003b.
-
(2003)
Int. J. Geriatr. Psychiatry
, vol.18
, pp. S1-S5
-
-
Giacobini, E.1
-
126
-
-
0343037749
-
-
Eds., Taylor and Francis, New York
-
Giacobini, E. and Becker, R., Eds.: "Current Research in Alzheimer Therapy, " Taylor and Francis, New York, 1988.
-
(1988)
Current Research in Alzheimer Therapy
-
-
Giacobini, E.1
Becker, R.2
-
127
-
-
12344254945
-
Evaluation of cholinergic markers in Alzheimer's disease and in model of cholinergic deficits
-
Gil-Bea, F. J., Garcia-Alloza, M., Dominquez, J., Marcos, B. and Ramirez, M. J.: Evaluation of cholinergic markers in Alzheimer's disease and in model of cholinergic deficits. Neurosci. Lett. 375: 37-41, 2005.
-
(2005)
Neurosci. Lett.
, vol.375
, pp. 37-41
-
-
Gil-Bea, F.J.1
Garcia-Alloza, M.2
Dominquez, J.3
Marcos, B.4
Ramirez, M.J.5
-
128
-
-
0019153066
-
Amyloid deposits and amyloidosis
-
Glenner, G.: Amyloid deposits and amyloidosis. N. Engl. J. Med. 302: 1283-1292, 1980.
-
(1980)
N. Engl. J. Med.
, vol.302
, pp. 1283-1292
-
-
Glenner, G.1
-
129
-
-
0022977846
-
Editorial: Reactive systemic amyloidosis in cystic fibrosis and other disorders associated with chronic inflammation
-
Glenner, G.: Editorial: Reactive systemic amyloidosis in cystic fibrosis and other disorders associated with chronic inflammation. Arch. Pathol Lab. Med. 110: 873-877, 1986.
-
(1986)
Arch. Pathol Lab. Med.
, vol.110
, pp. 873-877
-
-
Glenner, G.1
-
130
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner, G. G. and Wong, C. W.: Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120: 885-890, 1984a.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
131
-
-
0021207461
-
Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
-
Glenner, G. G. and Wong, C. W.: Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein. Biochem. Biophys. Res. Commun. 122: 1131-1135, 1984b.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.122
, pp. 1131-1135
-
-
Glenner, G.G.1
Wong, C.W.2
-
132
-
-
84919967493
-
The nature and significance of cholinesterase
-
H. B. Lewis, Ed., Jacques Cattell Press, Lancaster, Penn
-
Glick, D.: The nature and significance of cholinesterase. In: "Comparative Biochemistry: Intermediate Metabolism of Fats, Carbohydrate Metabolism, Biochemistry of Choline, " H. B. Lewis, Ed., pp. 213-233, Jacques Cattell Press, Lancaster, Penn., 1941.
-
(1941)
Comparative Biochemistry: Intermediate Metabolism of Fats, Carbohydrate Metabolism, Biochemistry of Choline
, pp. 213-233
-
-
Glick, D.1
-
133
-
-
0015371027
-
Cholinergic effects on adrenergic neurotransmitters in rabbit brain parts
-
Glisson, S. N., Karczmar, A. G. and Barnes, L.: Cholinergic effects on adrenergic neurotransmitters in rabbit brain parts. Neuropharmacology 11: 465-477, 1972.
-
(1972)
Neuropharmacology
, vol.11
, pp. 465-477
-
-
Glisson, S.N.1
Karczmar, A.G.2
Barnes, L.3
-
134
-
-
0016138658
-
Effects of diisopropyl phosphorofluoridate on acetylcholine, cholinesterase and catecholamines of several parts of rabbit brain
-
Glisson, S. N., Karczmar, A. G. and Barnes, L.: Effects of diisopropyl phosphorofluoridate on acetylcholine, cholinesterase and catecholamines of several parts of rabbit brain. Neuropharmacology 13: 623-632, 1974.
-
(1974)
Neuropharmacology
, vol.13
, pp. 623-632
-
-
Glisson, S.N.1
Karczmar, A.G.2
Barnes, L.3
-
135
-
-
84914557083
-
Acetylcholinesterase activity and somatostatin-like immunoreactivity in lumbar cerebrospinal fluid of demented patients
-
A. Fisher, I. Hanin, and C. Lachman, Eds., Plenum Press, New York
-
Gomez, S., Davies, P., Faivre-Bauman, A., Valade, D., Jeannin, C., Rondot, P. and Puymirat, J.: Acetylcholinesterase activity and somatostatin-like immunoreactivity in lumbar cerebrospinal fluid of demented patients. In: "Alzheimer's and Parkinson's Diseases, " A. Fisher, I. Hanin, and C. Lachman, Eds., pp. 317-322, Plenum Press, New York, 1985.
-
(1985)
Alzheimer's and Parkinson's Diseases
, pp. 317-322
-
-
Gomez, S.1
Davies, P.2
Faivre-Bauman, A.3
Valade, D.4
Jeannin, C.5
Rondot, P.6
Puymirat, J.7
-
136
-
-
0035947772
-
Ecadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesionindependent manner
-
Gottardi, C. J., Wong, E. and Gumbiner, B. M.: Ecadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesionindependent manner. J. Cell Biol. 153(5): 1049-1060, 2001.
-
(2001)
J. Cell Biol.
, vol.153
, Issue.5
, pp. 1049-1060
-
-
Gottardi, C.J.1
Wong, E.2
Gumbiner, B.M.3
-
137
-
-
0035943436
-
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
-
Gotz, J., Chen, F., van Dorpe, J. and Nitsch, R. M.: Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Science 293(5534): 1491-1495, 2001.
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1491-1495
-
-
Gotz, J.1
Chen, F.2
Van Dorpe, J.3
Nitsch, R.M.4
-
138
-
-
0027318670
-
Induction of beta-amyloid precursor protein isoform mRNAs by bFGF in astrocytes
-
Gray, C. W. and Patel, A. J.: Induction of beta-amyloid precursor protein isoform mRNAs by bFGF in astrocytes. Neuroreport 4(6): 811-814, 1993.
-
(1993)
Neuroreport
, vol.4
, Issue.6
, pp. 811-814
-
-
Gray, C.W.1
Patel, A.J.2
-
139
-
-
0034806590
-
CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium
-
Grimes, C. A. and Jope, R. S.: CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium. J. Neurochem. 78(6): 1219-1232, 2001.
-
(2001)
J. Neurochem.
, vol.78
, Issue.6
, pp. 1219-1232
-
-
Grimes, C.A.1
Jope, R.S.2
-
140
-
-
0034745017
-
Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome
-
Gyure, K. A., Durham, R., Stewart, W. F., Smialek, J. E. and Troncoso, J. C.: Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome. Arch. Pathol. Lab. Med. 125(4): 489-492, 2001.
-
(2001)
Arch. Pathol. Lab. Med.
, vol.125
, Issue.4
, pp. 489-492
-
-
Gyure, K.A.1
Durham, R.2
Stewart, W.F.3
Smialek, J.E.4
Troncoso, J.C.5
-
141
-
-
0026646604
-
Amyloid beta-peptide is produced by cultured cells during normal metabolism
-
Haass, C., Schlossmacher, M. G., Hung, A. Y., Vigo- Pelfrey, C., Mellon, A., Ostaszewski, B. L., Lieberburg, I., Koo, E. H., Schenk, D., Teplow, D. B., et al.: Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature 359(6393): 322-325, 1992a.
-
(1992)
Nature
, vol.359
, Issue.6393
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostaszewski, B.L.6
Lieberburg, I.7
Koo, E.H.8
Schenk, D.9
Teplow, D.B.10
-
142
-
-
0026735070
-
Targeting of cell-surface beta-amyloid precursor protein to lysosomes: Alternative processing into amyloid-bearing fragments
-
Haass, C., Koo, E. H., Mellon, A., Hung, A. Y. and Selkoe, D. J.: Targeting of cell-surface beta-amyloid precursor protein to lysosomes: Alternative processing into amyloid-bearing fragments. Nature 357(6378): 500- 503, 1992b.
-
(1992)
Nature
, vol.357
, Issue.6378
, pp. 500-503
-
-
Haass, C.1
Koo, E.H.2
Mellon, A.3
Hung, A.Y.4
Selkoe, D.J.5
-
143
-
-
0031888035
-
Regulation of caveolin and caveolae by cholesterol in MDCK cells
-
Hailstones, D., Sleer, L. S., Parton, R. G. and Stanley, K. K.: Regulation of caveolin and caveolae by cholesterol in MDCK cells. J. Lipid Res. 39(2): 369-379, 1998.
-
(1998)
J. Lipid Res.
, vol.39
, Issue.2
, pp. 369-379
-
-
Hailstones, D.1
Sleer, L.S.2
Parton, R.G.3
Stanley, K.K.4
-
144
-
-
0037424260
-
Novel role for apolipoprotein E in the central nervous system: Modulation of sulfatide content
-
Han, X., Cheng, H., Fryer, J. D., Fagan, A. M. and Holtzman, D. M.: Novel role for apolipoprotein E in the central nervous system: modulation of sulfatide content. J. Biol. Chem. 278(10): 8043-8051, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.10
, pp. 8043-8051
-
-
Han, X.1
Cheng, H.2
Fryer, J.D.3
Fagan, A.M.4
Holtzman, D.M.5
-
145
-
-
0026443801
-
Effects of apolipoprotein E, beta-very low density lipoproteins, and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro
-
Handelmann, G. E., Boyles, J. K., Weisgraber, K. H., Mahley, R. W. and Pitas, R. E.: Effects of apolipoprotein E, beta-very low density lipoproteins, and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro. J. Lipid Res. 33(11): 1677-1688, 1992.
-
(1992)
J. Lipid Res.
, vol.33
, Issue.11
, pp. 1677-1688
-
-
Handelmann, G.E.1
Boyles, J.K.2
Weisgraber, K.H.3
Mahley, R.W.4
Pitas, R.E.5
-
146
-
-
0026487365
-
Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase
-
Hanger, D. P., Hughes, K., Woodgett, J. R., Brion, J. P. and Anderton, B. H.: Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci Lett. 147(1): 58-62, 1992.
-
(1992)
Neurosci Lett.
, vol.147
, Issue.1
, pp. 58-62
-
-
Hanger, D.P.1
Hughes, K.2
Woodgett, J.R.3
Brion, J.P.4
Anderton, B.H.5
-
147
-
-
0037205315
-
Glycogen synthase kinase-3beta: A novel regulator of cardiac hypertrophy and development
-
Hardt, S. E. and Sadoshima, J.: Glycogen synthase kinase-3beta: A novel regulator of cardiac hypertrophy and development. Circ. Res. 90(10): 1055-1063, 2002.
-
(2002)
Circ. Res.
, vol.90
, Issue.10
, pp. 1055-1063
-
-
Hardt, S.E.1
Sadoshima, J.2
-
148
-
-
0031751761
-
Mitogen-activated protein kinase-dependent and protein kinase C-dependent pathways link the m1 muscarinic receptor to beta-amyloid precursor protein secretion
-
Haring, R., Fisher, A., Marciano, D., Pittel, Z., Kloog, Y., Zuckerman, A., Eshhar, N. and Heldman, E.: Mitogen-activated protein kinase-dependent and protein kinase C-dependent pathways link the m1 muscarinic receptor to beta-amyloid precursor protein secretion. J. Neurochem. 71(5): 2094-2103, 1998.
-
(1998)
J. Neurochem.
, vol.71
, Issue.5
, pp. 2094-2103
-
-
Haring, R.1
Fisher, A.2
Marciano, D.3
Pittel, Z.4
Kloog, Y.5
Zuckerman, A.6
Eshhar, N.7
Heldman, E.8
-
149
-
-
0031890373
-
Beta-amyloid {Phe [(So3H) 24] 25-35} in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cholinergic innervation
-
Harkany, T., O'Mahoney, S. and Kelly, J. P.: Beta-amyloid {Phe [(So3H) 24] 25-35} in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cholinergic innervation. Behav. Brain Res. 90: 133-145, 1998.
-
(1998)
Behav. Brain Res.
, vol.90
, pp. 133-145
-
-
Harkany, T.1
O'Mahoney, S.2
Kelly, J.P.3
-
150
-
-
0032517134
-
Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro
-
Harper, S. J., Bilsland, J. G., Shearman, M. S., Zheng, H., Van der Ploeg, L. and Sirinathsinghji, D. J.: Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro. Neuroreport 9(13): 3053-3058, 1998.
-
(1998)
Neuroreport
, vol.9
, Issue.13
, pp. 3053-3058
-
-
Harper, S.J.1
Bilsland, J.G.2
Shearman, M.S.3
Zheng, H.4
Van Der Ploeg, L.5
Sirinathsinghji, D.J.6
-
151
-
-
0038410044
-
Gamma-secretase inhibitors- from molecular probes to new therapeutics?
-
Harrison, T. and Beher, D.: Gamma-secretase inhibitors- from molecular probes to new therapeutics? Prog. Med. Chem. 41: 99-127, 2003.
-
(2003)
Prog. Med. Chem.
, vol.41
, pp. 99-127
-
-
Harrison, T.1
Beher, D.2
-
152
-
-
0034870449
-
Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: ApoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuro pathology
-
Hartman, R. E., Wozniak, D. F., Nardi, A., Olney, J. W., Sartorius, L. and Holtzman, D. M.: Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: ApoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuro pathology. Exp. Neurol. 170(2): 326-344, 2001.
-
(2001)
Exp. Neurol.
, vol.170
, Issue.2
, pp. 326-344
-
-
Hartman, R.E.1
Wozniak, D.F.2
Nardi, A.3
Olney, J.W.4
Sartorius, L.5
Holtzman, D.M.6
-
153
-
-
0022549757
-
Nerve growth factor and Alzheimer's disease
-
Hefti, F. and Weiner, W. J.: Nerve growth factor and Alzheimer's disease. Ann. Neurol. 20: 275-281, 1986.
-
(1986)
Ann. Neurol.
, vol.20
, pp. 275-281
-
-
Hefti, F.1
Weiner, W.J.2
-
154
-
-
1642363745
-
Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments
-
Hernandez, F., Borrell, J., Guaza, C., Avila, J. and Lucas, J. J.: Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments. J. Neurochem. 83(6): 1529-1533, 2002.
-
(2002)
J. Neurochem.
, vol.83
, Issue.6
, pp. 1529-1533
-
-
Hernandez, F.1
Borrell, J.2
Guaza, C.3
Avila, J.4
Lucas, J.J.5
-
155
-
-
0037444574
-
Gamma-secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation
-
Herreman, A., Van Gassen, G., Bentahir, M., Nyabi, O., Craessaerts, K., Mueller, U., Annaert, W. and De Strooper, B.: Gamma-secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation. J. Cell Sci. 116, Pt. 6: 1127-1136, 2003.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1127-1136
-
-
Herreman, A.1
Van Gassen, G.2
Bentahir, M.3
Nyabi, O.4
Craessaerts, K.5
Mueller, U.6
Annaert, W.7
De Strooper, B.8
-
156
-
-
0020701177
-
Senile amyloidosis in senescence accelerated mice
-
Higuchi, K., Matsumara, A. and Honma, A.: Senile amyloidosis in senescence accelerated mice. Lab. Invest. 48: 231-240, 1983.
-
(1983)
Lab. Invest.
, vol.48
, pp. 231-240
-
-
Higuchi, K.1
Matsumara, A.2
Honma, A.3
-
157
-
-
4544246618
-
Comparison studies of cholinesterase inhibitors for Alzheimer's disease
-
Hogan, D. B., Goldlist, B., Naglie, G. and Patterson, C.: Comparison studies of cholinesterase inhibitors for Alzheimer's disease. Lancet Neurol. 3: 622-626, 2004.
-
(2004)
Lancet Neurol.
, vol.3
, pp. 622-626
-
-
Hogan, D.B.1
Goldlist, B.2
Naglie, G.3
Patterson, C.4
-
158
-
-
0029159875
-
Mutant and native human beta-amyloid precursor proteins in transgenic mouse brain
-
Howland, D. S., Savage, M. J., Huntress, F. A., Wallace, R. E., Schwartz, D. A., Loh, T., Melloni, R. H. Jr., DeGennaro, L. J., Greenberg, B. D., Siman, R., Swanson, M. E. and Scott, R. W.: Mutant and native human beta-amyloid precursor proteins in transgenic mouse brain. Neurobiol. Aging 16(4): 685-699, 1995.
-
(1995)
Neurobiol. Aging
, vol.16
, Issue.4
, pp. 685-699
-
-
Howland, D.S.1
Savage, M.J.2
Huntress, F.A.3
Wallace, R.E.4
Schwartz, D.A.5
Loh, T.6
Melloni, R.H.7
DeGennaro, L.J.8
Greenberg, B.D.9
Siman, R.10
Swanson, M.E.11
Scott, R.W.12
-
159
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
Hsia, A. Y., Masliah, E., McConlogue, L., Yu, G. Q., Tatsuno, G., Hu, K., Kholodenko, D., Malenka, R. C., Nicoll, R. A. and Mucke, L.: Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl. Acad. Sci. U.S.A. 96(6): 3228-3233, 1999.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, Issue.6
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
160
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F. and Cole, G.: Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274(5284): 99-102, 1996.
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
161
-
-
0033382226
-
Identification of a novel aspartic protease (Asp 2) as beta-secretase
-
Hussain, I., Powell, D., Howlett, D. R., Tew, D. G., Meek, T. D., Chapman, C., Gloger, I. S., Murphy, K. E., Southan, C. D., Ryan, D. M., Smith, T. S., Simmons, D. L., Walsh, F. S., Dingwall, C. and Christie, G.: Identification of a novel aspartic protease (Asp 2) as beta-secretase. Mol. Cell. Neurosci. 14(6): 419-427, 1999.
-
(1999)
Mol. Cell. Neurosci.
, vol.14
, Issue.6
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Howlett, D.R.3
Tew, D.G.4
Meek, T.D.5
Chapman, C.6
Gloger, I.S.7
Murphy, K.E.8
Southan, C.D.9
Ryan, D.M.10
Smith, T.S.11
Simmons, D.L.12
Walsh, F.S.13
Dingwall, C.14
Christie, G.15
-
162
-
-
0032562615
-
Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein
-
Ikezu, T., Trapp, B. D., Song, K. S., Schlegel, A., Lisanti, M. P. and Okamoto, T.: Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein. J. Biol. Chem. 273(17): 10485-10495, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.17
, pp. 10485-10495
-
-
Ikezu, T.1
Trapp, B.D.2
Song, K.S.3
Schlegel, A.4
Lisanti, M.P.5
Okamoto, T.6
-
163
-
-
0037697336
-
Inactivation of integrin-linked kinase induces aberrant Tau phosphorylation via sustained activation of glycogen synthase kinase 3beta in N1E-115 neuroblastoma cells
-
Ishii, T., Furuoka, H., Muroi, Y. and Nishimura, M.: Inactivation of integrin-linked kinase induces aberrant Tau phosphorylation via sustained activation of glycogen synthase kinase 3beta in N1E-115 neuroblastoma cells. J. Biol. Chem. 278(29): 26970- 26975, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.29
, pp. 26970-26975
-
-
Ishii, T.1
Furuoka, H.2
Muroi, Y.3
Nishimura, M.4
-
164
-
-
18544370897
-
Significance and mechanism of Alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion
-
Iqbal, K., Alonso Adel, C., El-Akkad, E., Gong, C. X., Haque, N., Khatoon, S., Pei, J. J., Tsujio, I., Wang, J. Z. and Grundke-Iqbal, I. Significance and mechanism of Alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion. J. Mol. Neurosci. 19(1-2): 95-99, 2002.
-
(2002)
J. Mol. Neurosci.
, vol.19
, Issue.1-2
, pp. 95-99
-
-
Iqbal, K.1
Alonso Adel, C.2
El-Akkad, E.3
Gong, C.X.4
Haque, N.5
Khatoon, S.6
Pei, J.J.7
Tsujio, I.8
Wang, J.Z.9
Grundke-Iqbal, I.10
-
165
-
-
0037606205
-
Vaccines for Alzheimer's disease: How close are we?
-
Janus, C.: Vaccines for Alzheimer's disease: How close are we? CNS Drugs. 17(7): 457-474, 2003.
-
(2003)
CNS Drugs
, vol.17
, Issue.7
, pp. 457-474
-
-
Janus, C.1
-
166
-
-
0034638746
-
Statins and the risk of dementia
-
Jick, H., Zornberg, G. L., Jick, S. S., Seshadri, S. and Drachman, D. A.: Statins and the risk of dementia. Lancet 356(9242): 1627-1631, 2000.
-
(2000)
Lancet
, vol.356
, Issue.9242
, pp. 1627-1631
-
-
Jick, H.1
Zornberg, G.L.2
Jick, S.S.3
Seshadri, S.4
Drachman, D.A.5
-
167
-
-
0141818331
-
Have cholinergic therapies reached their clinical boundary in Alzheimer's disease?
-
Jones, R. W.: Have cholinergic therapies reached their clinical boundary in Alzheimer's disease? Int. J. Geriatr. Psychiatry 18, Supplt. 18: S7-S13, 2003.
-
(2003)
Int. J. Geriatr. Psychiatry
, vol.18
, pp. S7-S13
-
-
Jones, R.W.1
-
168
-
-
0035816709
-
Cholesterol-dependent formation of GM1 ganglioside-bound amyloid betaprotein, an endogenous seed for Alzheimer amyloid
-
Kakio, A., Nishimoto, S. I., Yanagisawa, K., Kozutsumi, Y. and Matsuzaki, K.: Cholesterol-dependent formation of GM1 ganglioside-bound amyloid betaprotein, an endogenous seed for Alzheimer amyloid. J. Biol. Chem. 276(27): 24985-24990, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.27
, pp. 24985-24990
-
-
Kakio, A.1
Nishimoto, S.I.2
Yanagisawa, K.3
Kozutsumi, Y.4
Matsuzaki, K.5
-
169
-
-
0035818998
-
Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin- 1 requires APP
-
Kamal, A., Almenar-Queralt, A., LeBlanc, J. F., et al.: Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin- 1 requires APP. Nature 414: 643-648, 2001.
-
(2001)
Nature
, vol.414
, pp. 643-648
-
-
Kamal, A.1
Almenar-Queralt, A.2
LeBlanc, J.F.3
-
170
-
-
0037145062
-
Presenilin couples the paired phosphorylation of beta-catenin independent of axin: Implications for beta-catenin activation in tumorigenesis
-
Kang, D. E., Soriano, S., Xia, X., Eberhart, C. G., De Strooper, B., Zheng, H., Koo, E. H.: Presenilin couples the paired phosphorylation of beta-catenin independent of axin: Implications for beta-catenin activation in tumorigenesis. Cell 110(6): 751-762, 2002.
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 751-762
-
-
Kang, D.E.1
Soriano, S.2
Xia, X.3
Eberhart, C.G.4
De Strooper, B.5
Zheng, H.6
Koo, E.H.7
-
171
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang, J., Lemaire, H. G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K. H., Multhaup, G., Beyreuther, K. and Muller-Hill, B.: The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325(6106): 733-736, 1987.
-
(1987)
Nature
, vol.325
, Issue.6106
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
172
-
-
0010462888
-
Pharmacologic, toxicologic, and therapeutic properties of anticholinesterase agents
-
W. S. Root and F. G. Hofman, Eds., Academic Press, New York
-
Karczmar, A. G.: Pharmacologic, toxicologic, and therapeutic properties of anticholinesterase agents. In: "Physiological Pharmacology, " W. S. Root and F. G. Hofman, Eds., vol. 3, pp. 163-322, Academic Press, New York, 1967.
-
(1967)
Physiological Pharmacology
, vol.3
, pp. 163-322
-
-
Karczmar, A.G.1
-
173
-
-
84915643684
-
New roles for cholinergics in CNS disease
-
Karczmar, A. G.: New roles for cholinergics in CNS disease. Drug Ther. 4: 31-42, 1979.
-
(1979)
Drug Ther.
, vol.4
, pp. 31-42
-
-
Karczmar, A.G.1
-
174
-
-
0010463276
-
SDAT models and their dynamics
-
R. Becker and E. Giacobini, Eds., Birkhaeuser, Boston
-
Karczmar, A. G.: SDAT models and their dynamics. In: "Cholinergic Basis for Alzheimer Therapy, " R. Becker and E. Giacobini, Eds., pp. 141-152, Birkhaeuser, Boston, 1991.
-
(1991)
Cholinergic Basis for Alzheimer Therapy
, pp. 141-152
-
-
Karczmar, A.G.1
-
175
-
-
0028906149
-
Cholinergic substrates of cognition and organism-environment interaction
-
Karczmar, A. G.: Cholinergic substrates of cognition and organism-environment interaction. Prog. Neuropsychopharmacol. Biol. Psychiatry 19: 187-211, 1995.
-
(1995)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.19
, pp. 187-211
-
-
Karczmar, A.G.1
-
176
-
-
0010423622
-
Effects of anticholinesterases pertinent for SDAT treatment but not necessarily underlying their clinical effectiveness
-
E. Giacobini and R. Becker, Eds., Taylor and Francis, New York
-
Karczmar, A. G. and Dun, N. J.: Effects of anticholinesterases pertinent for SDAT treatment but not necessarily underlying their clinical effectiveness. In: "Current Research in Alzheimer Therapy, " E. Giacobini and R. Becker, Eds., pp. 15-29, Taylor and Francis, New York, 1988.
-
(1988)
Current Research in Alzheimer Therapy
, pp. 15-29
-
-
Karczmar, A.G.1
Dun, N.J.2
-
177
-
-
0347284323
-
Effects of amyloid-beta on cholinergic and acetylcholinesterase-positive cells in cultured basal forebrain neurons of embryonic rat brain
-
Kasa, P. Sr., Papp, H., Kasa, P. Jr., Pakaski, M. and Balaspiri, L.: Effects of amyloid-beta on cholinergic and acetylcholinesterase-positive cells in cultured basal forebrain neurons of embryonic rat brain. Brain Res. 998: 73-82, 2004.
-
(2004)
Brain Res.
, vol.998
, pp. 73-82
-
-
Kasa, P.1
Papp, H.2
Kasa, P.3
Pakaski, M.4
Balaspiri, L.5
-
178
-
-
0034832025
-
Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation
-
Kawamura, Y., Kikuchi, A., Takada, R., Takada, S., Sudoh, S., Shibamoto, S., Yanagisawa, K. and Komano, H. Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation. Eur. J. Biochem. 268(10): 3036-3041, 2001.
-
(2001)
Eur. J. Biochem.
, vol.268
, Issue.10
, pp. 3036-3041
-
-
Kawamura, Y.1
Kikuchi, A.2
Takada, R.3
Takada, S.4
Sudoh, S.5
Shibamoto, S.6
Yanagisawa, K.7
Komano, H.8
-
179
-
-
0242525080
-
A randomized placebo controlled study to assess the effects of cholinergic treatment on muscarinic receptors in Alzheimer's disease
-
Kemp, P. M., Holmes, C., Hoffman, S., Wilkinson, S., Zivanovic, M., Thom, J., Bolt, L., Fleming, J. and Wilkinson, D. G.: A randomized placebo controlled study to assess the effects of cholinergic treatment on muscarinic receptors in Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 74: 1567-1570, 2003.
-
(2003)
J. Neurol. Neurosurg. Psychiatry
, vol.74
, pp. 1567-1570
-
-
Kemp, P.M.1
Holmes, C.2
Hoffman, S.3
Wilkinson, S.4
Zivanovic, M.5
Thom, J.6
Bolt, L.7
Fleming, J.8
Wilkinson, D.G.9
-
180
-
-
0035126176
-
P35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction
-
Kesavapany, S., Lau, K. F., McLoughlin, D. M., Brownlees, J., Ackerley, S., Leigh, P. N., Shaw, C. E. and Miller, C. C.: P35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction. Eur. J. Neurosci. 13(2): 241-247, 2001.
-
(2001)
Eur. J. Neurosci.
, vol.13
, Issue.2
, pp. 241-247
-
-
Kesavapany, S.1
Lau, K.F.2
McLoughlin, D.M.3
Brownlees, J.4
Ackerley, S.5
Leigh, P.N.6
Shaw, C.E.7
Miller, C.C.8
-
181
-
-
0038538234
-
Imaging methods for evaluating brain function in man
-
Kessler, R. M.: Imaging methods for evaluating brain function in man. Neurobiol. Aging 24, Supplt. 1: S21-S35, 2003.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. S21-S35
-
-
Kessler, R.M.1
-
182
-
-
0035930522
-
Presenilin 1 independently regulates beta-catenin stability and transcriptional activity
-
Killick, R., Pollard, C. C., Asuni, A. A., Mudher, A. K., Richardson, J. C., Rupniak, H. T., Sheppard, P. W., Varndell, I. M., Brion, J. P., Levey, A. I., Levy, O. A., Vestling, M., Cowburn, R., Lovestone, S. and Anderton, B. H.: Presenilin 1 independently regulates beta-catenin stability and transcriptional activity. J. Biol. Chem. 276(51): 48554-48561, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.51
, pp. 48554-48561
-
-
Killick, R.1
Pollard, C.C.2
Asuni, A.A.3
Mudher, A.K.4
Richardson, J.C.5
Rupniak, H.T.6
Sheppard, P.W.7
Varndell, I.M.8
Brion, J.P.9
Levey, A.I.10
Levy, O.A.11
Vestling, M.12
Cowburn, R.13
Lovestone, S.14
Anderton, B.H.15
-
183
-
-
0000792598
-
The transmembrane aspartates in presentilin 1 and 2 are obligatory for gammasecretase activity and amyloid beta-protein generation
-
Kimberly, W. T., Xia, W., Rahmati, T., Wolfe, M. S. and Selkoe, D. J.: The transmembrane aspartates in presentilin 1 and 2 are obligatory for gammasecretase activity and amyloid beta-protein generation. J. Biol. Chem. 275: 3173-3178, 2000.
-
(2000)
J. Biol. Chem., 3173-3178
, vol.275
-
-
Kimberly, W.T.1
Xia, W.2
Rahmati, T.3
Wolfe, M.S.4
Selkoe, D.J.5
-
184
-
-
0038652102
-
Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2
-
Kimberly, W. T., LaVoie, M. J., Ostaszewski, B. L., Ye, W., Wolfe, M. S. and Selkoe, D. J.: Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2. Proc. Natl. Acad. Sci. U.S.A. 100(11): 6382-6387, 2003.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, Issue.11
, pp. 6382-6387
-
-
Kimberly, W.T.1
LaVoie, M.J.2
Ostaszewski, B.L.3
Ye, W.4
Wolfe, M.S.5
Selkoe, D.J.6
-
185
-
-
0036677928
-
Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: Association with Fe65 and translocation to the nucleus
-
Kinoshita, A., Whelan, C. M., Smith, C. J., Berezovska, O. and Hyman, B. T.: Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: Association with Fe65 and translocation to the nucleus. J. Neurochem. 82(4): 839-847, 2002.
-
(2002)
J. Neurochem.
, vol.82
, Issue.4
, pp. 839-847
-
-
Kinoshita, A.1
Whelan, C.M.2
Smith, C.J.3
Berezovska, O.4
Hyman, B.T.5
-
186
-
-
0023872043
-
Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity
-
Kitaguchi, N., Takahashi, Y., Tokushima, Y., Shiojiri, S. and Ito, H.: Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature 331(6156): 530-532, 1988.
-
(1988)
Nature
, vol.331
, Issue.6156
, pp. 530-532
-
-
Kitaguchi, N.1
Takahashi, Y.2
Tokushima, Y.3
Shiojiri, S.4
Ito, H.5
-
187
-
-
0000748464
-
Experimental production of neurofibrillary degeneration
-
Klatzo, I., Wisniewski, H. M. and Streiker, E.: Experimental production of neurofibrillary degeneration. J. Neuropathol. Exp. Neurol. 24: 1187-1199, 1965.
-
(1965)
J. Neuropathol. Exp. Neurol.
, vol.24
, pp. 1187-1199
-
-
Klatzo, I.1
Wisniewski, H.M.2
Streiker, E.3
-
188
-
-
0037337271
-
Dissecting the assembly of abeta(16-22) amyloid peptides into antiparallel Beta sheets
-
Klimov, D. K. and Thirumalai, D.: Dissecting the assembly of abeta(16-22) amyloid peptides into antiparallel Beta sheets. Structure (Camb.) 11(3): 295-307, 2003.
-
(2003)
Structure (Camb.)
, vol.11
, Issue.3
, pp. 295-307
-
-
Klimov, D.K.1
Thirumalai, D.2
-
189
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha - secretase ADAM 10
-
Kojro, E., Gimpl, G., Lammich, S., Marz, W. and Fahrenholz, F.: Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha - secretase ADAM 10. Proc. Natl. Acad. Sci. U.S.A. 98(10): 5815-5820, 2001.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, Issue.10
, pp. 5815-5820
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
Marz, W.4
Fahrenholz, F.5
-
190
-
-
0028276801
-
Evidence that production and release of amyloid beta-protein involves the endocytic pathway
-
Koo, E. H. and Squazzo, S. L.: Evidence that production and release of amyloid beta-protein involves the endocytic pathway. J. Biol. Chem. 269(26): 17386- 17389, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, Issue.26
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.L.2
-
191
-
-
0034669031
-
A common enzyme connects notch signaling and Alzheimer's disease
-
Kopan, R. and Goate, A.: A common enzyme connects notch signaling and Alzheimer's disease. Genes Dev. 14(22): 2799-2806, 2000.
-
(2000)
Genes Dev.
, vol.14
, Issue.22
, pp. 2799-2806
-
-
Kopan, R.1
Goate, A.2
-
192
-
-
0033387397
-
Beta-amyloid deposition and neurofibrillary tangle formation in the olfactory bulb in ageing and Alzheimer's disease
-
Kovacs, T., Cairns, N. J. and Lantos, P. L.: Beta-amyloid deposition and neurofibrillary tangle formation in the olfactory bulb in ageing and Alzheimer's disease. Neuropathol. Appl. Neurobiol. 25(6): 481-491, 1999.
-
(1999)
Neuropathol. Appl. Neurobiol.
, vol.25
, Issue.6
, pp. 481-491
-
-
Kovacs, T.1
Cairns, N.J.2
Lantos, P.L.3
-
193
-
-
0004219440
-
-
Band. Johann Ambrosius Barth Verlag, Leipzig
-
Kraepelin, E.: "Lehrbuch der Psychiatry, " II Band. Johann Ambrosius Barth Verlag, Leipzig, 1910.
-
(1910)
Lehrbuch Der Psychiatry
, vol.2
-
-
Kraepelin, E.1
-
194
-
-
0035341309
-
SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis
-
Lang, T., Bruns, D., Wenzel, D., Riedel, D., Holroyd, P., Thiele, C. and Jahn, R.: SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis. EMBO J 20(9): 2202-2213, 2001.
-
(2001)
EMBO J
, vol.20
, Issue.9
, pp. 2202-2213
-
-
Lang, T.1
Bruns, D.2
Wenzel, D.3
Riedel, D.4
Holroyd, P.5
Thiele, C.6
Jahn, R.7
-
195
-
-
0033198715
-
Molecular cloning and characterization of the human glycogen synthase kinase-3beta promoter
-
Lau, K. F., Miller, C. C., Anderton, B. H. and Shaw, P. C.: Molecular cloning and characterization of the human glycogen synthase kinase-3beta promoter. Genomics 60(2): 121-128, 1999.
-
(1999)
Genomics
, vol.60
, Issue.2
, pp. 121-128
-
-
Lau, K.F.1
Miller, C.C.2
Anderton, B.H.3
Shaw, P.C.4
-
196
-
-
0346655318
-
The neurobiology of nicotine addiction: Bridging the gap from molecules to behavior
-
Laviolette, S. R. and van der Kooy, I.: The neurobiology of nicotine addiction: Bridging the gap from molecules to behavior. Nat. Rev. Neurosci. 5: 55-65, 2004.
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 55-65
-
-
Laviolette, S.R.1
Van Der Kooy, I.2
-
197
-
-
20044396527
-
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: Revisited
-
Lazarov, O., Morfini, G. A., Lee, E. B., Farah, M. H., Szodora, A., DeBeer, S. K., Koliatsos, V. E., King, S., Lee, V. M., Wong, P. C., Price, D. L., Brady, S. T. and Sisodia, S. S.: Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: Revisited. J. Neurosci. 25: 2386-2395, 2005.
-
(2005)
J. Neurosci.
, vol.25
, pp. 2386-2395
-
-
Lazarov, O.1
Morfini, G.A.2
Lee, E.B.3
Farah, M.H.4
Szodora, A.5
DeBeer, S.K.6
Koliatsos, V.E.7
King, S.8
Lee, V.M.9
Wong, P.C.10
Price, D.L.11
Brady, S.T.12
Sisodia, S.S.13
-
198
-
-
0344406228
-
Glycogen synthase kinase-3 beta-mediated tau phosphorylation in cultured cell lines
-
Lee, C. W., Lau, K. F., Miller, C. C. and Shaw, P. C.: Glycogen synthase kinase-3 beta-mediated tau phosphorylation in cultured cell lines. Neuroreport 14(2): 257-260, 2003.
-
(2003)
Neuroreport
, vol.14
, Issue.2
, pp. 257-260
-
-
Lee, C.W.1
Lau, K.F.2
Miller, C.C.3
Shaw, P.C.4
-
199
-
-
0037155219
-
Presenilindependent gamma-secretase-like intramembrane cleavage of ErbB4
-
Lee, H. J., Jung, K. M., Huang, Y. Z., Bennett, L. B., Lee, J. S., Mei, L. and Kim, T. W.: Presenilindependent gamma-secretase-like intramembrane cleavage of ErbB4. J. Biol. Chem. 277(8): 6318- 6323, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.8
, pp. 6318-6323
-
-
Lee, H.J.1
Jung, K.M.2
Huang, Y.Z.3
Bennett, L.B.4
Lee, J.S.5
Mei, L.6
Kim, T.W.7
-
200
-
-
0031746979
-
A detergent-insoluble membrane compartment contains A beta in vivo
-
Lee, S. J., Liyanage, U., Bickel, P. E., Xia, W., Lansbury, P. T. Jr. and Kosik, K. S.: A detergent-insoluble membrane compartment contains A beta in vivo. Nat. Med. 4(6): 730-734, 1998.
-
(1998)
Nat. Med.
, vol.4
, Issue.6
, pp. 730-734
-
-
Lee, S.J.1
Liyanage, U.2
Bickel, P.E.3
Xia, W.4
Lansbury, P.T.5
Kosik, K.S.6
-
201
-
-
0034682541
-
Calsenilin reverses presenilin-mediated enhancement of calcium signaling
-
Leissring, M. A., Yamasaki, T. R., Wasco, W., Buxbaum, J. D., Parker, I. and LaFerla, F. M.: Calsenilin reverses presenilin-mediated enhancement of calcium signaling. Proc. Natl. Acad. Sci. U.S.A. 97(15): 8590-8593, 2000.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, Issue.15
, pp. 8590-8593
-
-
Leissring, M.A.1
Yamasaki, T.R.2
Wasco, W.3
Buxbaum, J.D.4
Parker, I.5
LaFerla, F.M.6
-
202
-
-
0037007140
-
A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP
-
Leissring, M. A., Murphy, M. P., Mead, T. R., Akbari, Y., Sugarman, M. C., Jannatipour, M., Anliker, B., Muller, U., Saftig, P., De Strooper, B., Wolfe, M. S., Golde, T. E. and LaFerla, F. M.: A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP. Proc. Natl. Acad. Sci. U.S.A. 99(7): 4697-4702, 2002.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, Issue.7
, pp. 4697-4702
-
-
Leissring, M.A.1
Murphy, M.P.2
Mead, T.R.3
Akbari, Y.4
Sugarman, M.C.5
Jannatipour, M.6
Anliker, B.7
Muller, U.8
Saftig, P.9
De Strooper, B.10
Wolfe, M.S.11
Golde, T.E.12
LaFerla, F.M.13
-
203
-
-
0036942638
-
The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease
-
Leroy, K., Boutajangout, A., Authelet, M., Woodgett, J. R., Anderton, B. H., Brion, J. P.: The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease. Acta Neuropathol. (Berl.) 103(2): 91- 99, 2002.
-
(2002)
Acta Neuropathol. (Berl.)
, vol.103
, Issue.2
, pp. 91-99
-
-
Leroy, K.1
Boutajangout, A.2
Authelet, M.3
Woodgett, J.R.4
Anderton, B.H.5
Brion, J.P.6
-
204
-
-
0038661168
-
Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate
-
Levites, Y., Amit, T., Mandel, S. and Youdim, M. B.: Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate. FASEB J. 17(8): 952-954, 2003.
-
(2003)
FASEB J.
, vol.17
, Issue.8
, pp. 952-954
-
-
Levites, Y.1
Amit, T.2
Mandel, S.3
Youdim, M.B.4
-
205
-
-
0034426011
-
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
-
Erratum in: Nat. Genet. 26(1): 127, 2000
-
Lewis, J., McGowan, E., Rockwood, J., Melrose, H., Nacharaju, P., Van Slegtenhorst, M., Gwinn-Hardy, K., Paul Murphy, M., Baker, M., Yu, X., Duff, K., Hardy, J., Corral, A., Lin, W. L., Yen, S. H., Dickson, D. W., Davies, P., Hutton, M.: Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet. 25(4): 402-405, 2000. Erratum in: Nat. Genet. 26(1): 127, 2000.
-
(2000)
Nat. Genet.
, vol.25
, Issue.4
, pp. 402-405
-
-
Lewis, J.1
McGowan, E.2
Rockwood, J.3
Melrose, H.4
Nacharaju, P.5
Van Slegtenhorst, M.6
Gwinn-Hardy, K.7
Paul Murphy, M.8
Baker, M.9
Yu, X.10
Duff, K.11
Hardy, J.12
Corral, A.13
Lin, W.L.14
Yen, S.H.15
Dickson, D.W.16
Davies, P.17
Hutton, M.18
-
206
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
Lewis, J., Dickson, D. W., Lin, W. L., Chisholm, L., Corral, A., Jones, G., Yen, S. H., Sahara, N., Skipper, L., Yager, D., Eckman, C., Hardy, J., Hutton, M. and McGowan, E.: Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 293(5534): 1487-1491, 2001.
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
-
207
-
-
24044456340
-
Novel dimeric AChE inhibitor Bis(7)- Tacrine but not donepezil, prevents glutamateinduced neuronal apoptosis by blocking NMDA receptors
-
Li, W., Pi, R., Chan, H. H., Lee, N. T., Tsang, H. W., Pu, Y., Chang, D. C., Li, C., Luo, J., Li, Z., Xue, H., Carlier, P. R., Pang, Y., Tsim, K. W., Li, M. and Han, Y.: Novel dimeric AChE inhibitor Bis(7)- Tacrine but not donepezil, prevents glutamateinduced neuronal apoptosis by blocking NMDA receptors. J. Biol. Chem., 280: 18179-18188, 2005.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18179-18188
-
-
Li, W.1
Pi, R.2
Chan, H.H.3
Lee, N.T.4
Tsang, H.W.5
Pu, Y.6
Chang, D.C.7
Li, C.8
Luo, J.9
Li, Z.10
Xue, H.11
Carlier, P.R.12
Pang, Y.13
Tsim, K.W.14
Li, M.15
Han, Y.16
-
208
-
-
0036251786
-
Calsenilin enhances apoptosis by altering endoplasmic reticulum calcium signaling
-
Lilliehook, C., Chan, S., Choi, E. K., Zaidi, N. F., Wasco, W., Mattson, M. P. and Buxbaum, J. D.: Calsenilin enhances apoptosis by altering endoplasmic reticulum calcium signaling. Mol. Cell. Neurosci. 19(4): 552-559, 2002.
-
(2002)
Mol. Cell. Neurosci.
, vol.19
, Issue.4
, pp. 552-559
-
-
Lilliehook, C.1
Chan, S.2
Choi, E.K.3
Zaidi, N.F.4
Wasco, W.5
Mattson, M.P.6
Buxbaum, J.D.7
-
209
-
-
0022263642
-
Apolipoprotein E gene mapping and expression: Localization of the structural gene to human chromosome 19 and expression of ApoE mRNA in lipoprotein- And non-lipoprotein-producing tissues
-
Lin-Lee, Y. C., Kao, F. T., Cheung, P. and Chan, L.: Apolipoprotein E gene mapping and expression: Localization of the structural gene to human chromosome 19 and expression of ApoE mRNA in lipoprotein- And non-lipoprotein-producing tissues. Biochemistry 24: 3751-3756, 1985.
-
(1985)
Biochemistry
, vol.24
, pp. 3751-3756
-
-
Lin-Lee, Y.C.1
Kao, F.T.2
Cheung, P.3
Chan, L.4
-
210
-
-
13444291406
-
Paradigm shift in NMDA receptor antagonist drug development. Molecular mechanism of uncompetitive inhibition by memantine in the treatment of Alzheimer's disease and other neurological disorders
-
Lipton, S. A.: Paradigm shift in NMDA receptor antagonist drug development. Molecular mechanism of uncompetitive inhibition by memantine in the treatment of Alzheimer's disease and other neurological disorders. J. Alzheimers Dis. 6, Supplt. 6: S61-S74, 2004.
-
(2004)
J. Alzheimers Dis.
, vol.6
, pp. S61-S74
-
-
Lipton, S.A.1
-
211
-
-
0037163879
-
Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta
-
Liu, F., Iqbal, K., Grundke-Iqbal, I. and Gong, C. X.: Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta. FEBS Lett. 530(1-3): 209-214, 2002.
-
(2002)
FEBS Lett.
, vol.530
, Issue.1-3
, pp. 209-214
-
-
Liu, F.1
Iqbal, K.2
Grundke-Iqbal, I.3
Gong, C.X.4
-
212
-
-
0242523117
-
The effect of cholinesterase inhibitors on the regional blood flow in patients with Alzheimer's disease and vascular dementia
-
Lojkowska, W., Ryglewicz, D., Jedrzejczak, T., Mine, S., Jakubowska, T., Jarosz, H. and Bochynska, A. J.: The effect of cholinesterase inhibitors on the regional blood flow in patients with Alzheimer's disease and vascular dementia. Neurol. Sci. 216: 119-126, 2003.
-
(2003)
Neurol. Sci.
, vol.216
, pp. 119-126
-
-
Lojkowska, W.1
Ryglewicz, D.2
Jedrzejczak, T.3
Mine, S.4
Jakubowska, T.5
Jarosz, H.6
Bochynska, A.J.7
-
213
-
-
0038679745
-
Chronic exposure to anticholinergic medication adversely affects the course of Alzheimer's disease
-
Lu, S. and Tune, L. E.: Chronic exposure to anticholinergic medication adversely affects the course of Alzheimer's disease. Am. J. Geriatr. Psychiatry 11: 458-461, 2003.
-
(2003)
Am. J. Geriatr. Psychiatry
, vol.11
, pp. 458-461
-
-
Lu, S.1
Tune, L.E.2
-
214
-
-
0019614994
-
Senescence: Pathology facing medicine's ultimate issue
-
Ludwig, F. C.: Senescence: Pathology facing medicine's ultimate issue. Arch. Pathol. Lab. Med. 105: 445- 451, 1981.
-
(1981)
Arch. Pathol. Lab. Med.
, vol.105
, pp. 445-451
-
-
Ludwig, F.C.1
-
215
-
-
0037424275
-
PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1
-
Luo, W. J., Wang, H., Li, H., Kim, B. S., Shah, S., Lee, H. J., Thinakaran, G., Kim, T. W., Yu, G. and Xu, H.: PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1. J. Biol. Chem. 278(10): 7850-7854, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.10
, pp. 7850-7854
-
-
Luo, W.J.1
Wang, H.2
Li, H.3
Kim, B.S.4
Shah, S.5
Lee, H.J.6
Thinakaran, G.7
Kim, T.W.8
Yu, G.9
Xu, H.10
-
216
-
-
0035116273
-
Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation
-
Luo, Y., Bolon, B., Kahn, S., Bennett, B. D., Babu- Khan, S., Denis, P., Fan, W., Kha, H., Zhang, J., Gong, Y., Martin, L., Louis, J. C., Yan, Q., Richards, W. G., Citron, M. and Vassar, R.: Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation. Nat. Neurosci. 4(3): 231-232, 2001.
-
(2001)
Nat. Neurosci.
, vol.4
, Issue.3
, pp. 231-232
-
-
Luo, Y.1
Bolon, B.2
Kahn, S.3
Bennett, B.D.4
Babu- Khan, S.5
Denis, P.6
Fan, W.7
Kha, H.8
Zhang, J.9
Gong, Y.10
Martin, L.11
Louis, J.C.12
Yan, Q.13
Richards, W.G.14
Citron, M.15
Vassar, R.16
-
217
-
-
0034831233
-
The protein kinase Cdk5: Structural aspects, roles in neurogenesis and involvement in Alzheimers pathology
-
Maccioni, R. B., Otth, C., Concha, I. I. and Munoz, J. P.: The protein kinase Cdk5: Structural aspects, roles in neurogenesis and involvement in Alzheimers pathology. Eur. J. Biochem. 268(6): 1518-1527, 2001.
-
(2001)
Eur. J. Biochem.
, vol.268
, Issue.6
, pp. 1518-1527
-
-
Maccioni, R.B.1
Otth, C.2
Concha, I.I.3
Munoz, J.P.4
-
218
-
-
0024299370
-
Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
-
Mahley, R. W.: Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology. Science 240(4852): 622-630, 1988.
-
(1988)
Science
, vol.240
, Issue.4852
, pp. 622-630
-
-
Mahley, R.W.1
-
219
-
-
0035827702
-
Retention of the Alzheimer's amyloid precursor fragment C99 in the endoplasmic reticulum prevents formation of amyloid beta-peptide
-
Maltese, W. A., Wilson, S., Tan, Y., Suomensaari, S., Sinha, S., Barbour, R. and McConlogue, L.: Retention of the Alzheimer's amyloid precursor fragment C99 in the endoplasmic reticulum prevents formation of amyloid beta-peptide. J. Biol. Chem. 276(23): 20267-20279, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.23
, pp. 20267-20279
-
-
Maltese, W.A.1
Wilson, S.2
Tan, Y.3
Suomensaari, S.4
Sinha, S.5
Barbour, R.6
McConlogue, L.7
-
220
-
-
18344380083
-
A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions
-
Marambaud, P., Shioi, J., Serban, G., Georgakopoulos, A., Sarner, S., Nagy, V., Baki, L., Wen, P., Efthimiopoulos, S., Shao, Z., Wisniewski, T. and Robakis, N. K.: A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. EMBO J. 21(8): 1948-1956, 2002.
-
(2002)
EMBO J.
, vol.21
, Issue.8
, pp. 1948-1956
-
-
Marambaud, P.1
Shioi, J.2
Serban, G.3
Georgakopoulos, A.4
Sarner, S.5
Nagy, V.6
Baki, L.7
Wen, P.8
Efthimiopoulos, S.9
Shao, Z.10
Wisniewski, T.11
Robakis, N.K.12
-
221
-
-
0038293404
-
APP processing enzymes (secretases) as therapeutic targets: Insights from the use of transgenics (Tgs) and transfected cells
-
Marks, N. and Berg, M. J.: APP processing enzymes (secretases) as therapeutic targets: Insights from the use of transgenics (Tgs) and transfected cells. Neurochem. Res. 28(7): 1049-1062, 2003.
-
(2003)
Neurochem. Res.
, vol.28
, Issue.7
, pp. 1049-1062
-
-
Marks, N.1
Berg, M.J.2
-
222
-
-
0038006958
-
Antioxidant vitamins E and C and risk of Alzheimer's disease
-
Martin, A.: Antioxidant vitamins E and C and risk of Alzheimer's disease. Nutr. Rev. 61(2): 69-73, 2003.
-
(2003)
Nutr. Rev.
, vol.61
, Issue.2
, pp. 69-73
-
-
Martin, A.1
-
223
-
-
0026075978
-
Secretase, " Alzheimer amyloid protein precursor secreting enzyme is not sequence-specific
-
Maruyama, K., Kametani, F., Usami, M., Yamao- Harigaya, W. and Tanaka, K.: "Secretase, " Alzheimer amyloid protein precursor secreting enzyme is not sequence-specific. Biochem. Biophys. Res. Commun. 179(3): 1670-1676, 1991.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.179
, Issue.3
, pp. 1670-1676
-
-
Maruyama, K.1
Kametani, F.2
Usami, M.3
Yamao- Harigaya, W.4
Tanaka, K.5
-
224
-
-
0028898888
-
Mechanisms of synaptic dysfunction in Alzheimer's disease
-
Masliah, E.: Mechanisms of synaptic dysfunction in Alzheimer's disease. Histol. Histopathol. 10(2): 509-519, 1995.
-
(1995)
Histol. Histopathol.
, vol.10
, Issue.2
, pp. 509-519
-
-
Masliah, E.1
-
225
-
-
0026743208
-
Amyloid precursor protein is localized in growing neurites of neonatal rat brain
-
Masliah, E., Mallory, M., Ge, N. and Saitoh, T.: Amyloid precursor protein is localized in growing neurites of neonatal rat brain. Brain Res. 593: 323-337, 1992.
-
(1992)
Brain Res.
, vol.593
, pp. 323-337
-
-
Masliah, E.1
Mallory, M.2
Ge, N.3
Saitoh, T.4
-
226
-
-
0345276627
-
Positron emission tomography radiochemistry
-
Mason, N. S. and Mathis, C. A.: Positron emission tomography radiochemistry. Neuroimaging Clin. N. Am. 13: 671-687, 2003.
-
(2003)
Neuroimaging Clin. N. Am.
, vol.13
, pp. 671-687
-
-
Mason, N.S.1
Mathis, C.A.2
-
227
-
-
0036674066
-
Alzheimer's therapeutics: Neurotrophin small molecule mimetics
-
Massa, S. M., Xie, Y. and Longo, F. M.: Alzheimer's therapeutics: Neurotrophin small molecule mimetics. J. Mol. Neurosci. 19: 107-111, 2002.
-
(2002)
J. Mol. Neurosci.
, vol.19
, pp. 107-111
-
-
Massa, S.M.1
Xie, Y.2
Longo, F.M.3
-
228
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer disease and Down syndrome
-
Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L. and Beyreuther, K.: Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. U.S.A. 82(12): 4245-4249, 1985.
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, Issue.12
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
Multhaup, G.4
McDonald, B.L.5
Beyreuther, K.6
-
229
-
-
0041695298
-
Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells
-
Mazzucchelli, M., Porello, E., Viletti-Pietra, C., Govoni, S. and Racchi, M.: Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells. J. Neural Transm. 110: 935-947, 2003.
-
(2003)
J. Neural Transm.
, vol.110
, pp. 935-947
-
-
Mazzucchelli, M.1
Porello, E.2
Viletti-Pietra, C.3
Govoni, S.4
Racchi, M.5
-
230
-
-
0021246085
-
Aging, Alzheimer's disease and the cholinergic system of the basal forebrain
-
McGeer, P. L., McGeer, E. G., Suzuki, J., Dolman, C. E. and Nagai, T.: Aging, Alzheimer's disease and the cholinergic system of the basal forebrain. Neurology 34: 741-745, 1984.
-
(1984)
Neurology
, vol.34
, pp. 741-745
-
-
McGeer, P.L.1
McGeer, E.G.2
Suzuki, J.3
Dolman, C.E.4
Nagai, T.5
-
231
-
-
0029811901
-
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
-
McGeer, P. L., Schulzer, M. and McGeer, E. G.: Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies. Neurology 47(2): 425-432, 1996.
-
(1996)
Neurology
, vol.47
, Issue.2
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
232
-
-
24944524929
-
Brain cholinergic vulnerability: Relevance to behavior and disease
-
McKinney, M. and Jacksonville, M. C.: Brain cholinergic vulnerability: Relevance to behavior and disease. Biochem. Pharmacol. 70: 1115-1124, 2005.
-
(2005)
Biochem. Pharmacol.
, vol.70
, pp. 1115-1124
-
-
McKinney, M.1
Jacksonville, M.C.2
-
233
-
-
84912702537
-
Alois Alzheimer and his disease
-
G. E. Wolstenholme and M. O'Connor, Eds. Ciba Found. Churchill, London
-
McMenemey, W. H.: Alois Alzheimer and his disease. In: "Alzheimer's Disease, " G. E. Wolstenholme and M. O'Connor, Eds. Ciba Found., Churchill, London, 1970.
-
(1970)
Alzheimer's Disease
-
-
McMenemey, W.H.1
-
234
-
-
0002031187
-
Neuroanatomy of cholinesterases in the normal human brain and in Alzheimer's disease
-
E. Giacobini, Ed., Martin Dunitz, London
-
Mesulam, M. M.: Neuroanatomy of cholinesterases in the normal human brain and in Alzheimer's disease. In: "Cholinesterases and Cholinesterase Inhibitors, " E. Giacobini, Ed., pp. 121-137, Martin Dunitz, London, 2000.
-
(2000)
Cholinesterases and Cholinesterase Inhibitors
, pp. 121-137
-
-
Mesulam, M.M.1
-
235
-
-
0842304284
-
The cholinergic lesion of Alzheimer's disease: Pivotal factor or side show?
-
Mesulam, M. M.: The cholinergic lesion of Alzheimer's disease: Pivotal factor or side show? Learn. Mem. 11: 43-49, 2004.
-
(2004)
Learn. Mem.
, vol.11
, pp. 43-49
-
-
Mesulam, M.M.1
-
236
-
-
2542511697
-
Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum
-
Mesulam, M. M., Shaw, P., Mash, D. and Weintraub, S.: Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum. Ann. Neurol. 55: 815-828, 2004.
-
(2004)
Ann. Neurol.
, vol.55
, pp. 815-828
-
-
Mesulam, M.M.1
Shaw, P.2
Mash, D.3
Weintraub, S.4
-
237
-
-
0032960305
-
Regulation of amyloid precursor protein cleavage
-
Mills, J. and Reiner, P. B.: Regulation of amyloid precursor protein cleavage. J. Neurochem. 72(2): 443- 460, 1999.
-
(1999)
J. Neurochem.
, vol.72
, Issue.2
, pp. 443-460
-
-
Mills, J.1
Reiner, P.B.2
-
238
-
-
0037336857
-
Role of integrin-linked kinase in nerve growth factor-stimulated neurite outgrowth
-
Mills, J., Digicaylioglu, M., Legg, A. T., Young, C. E., Young, S. S., Barr, A. M., Fletcher, L., O'Connor, T. P. and Dedhar, S.: Role of integrin-linked kinase in nerve growth factor-stimulated neurite outgrowth. J. Neurosci. 23(5): 1638-1648, 2003.
-
(2003)
J. Neurosci.
, vol.23
, Issue.5
, pp. 1638-1648
-
-
Mills, J.1
Digicaylioglu, M.2
Legg, A.T.3
Young, C.E.4
Young, S.S.5
Barr, A.M.6
Fletcher, L.7
O'Connor, T.P.8
Dedhar, S.9
-
239
-
-
10744224126
-
What happens when donepezil is suddenly withdrawn? An open label trial in dementia with Lewy bodies and Parkinson's disease with dementia
-
Minett, T. S., Thomas, A., Wilkinson, L. M., Daniel, S. L., Sanders, J., Richardson, J., Littlewood, E., Myint, P., Newby, J. and McKeith, I. G.: What happens when donepezil is suddenly withdrawn? An open label trial in dementia with Lewy bodies and Parkinson's disease with dementia. Int. J. Geriatr. Psychiatry 18: 988-993, 2003.
-
(2003)
Int. J. Geriatr. Psychiatry
, vol.18
, pp. 988-993
-
-
Minett, T.S.1
Thomas, A.2
Wilkinson, L.M.3
Daniel, S.L.4
Sanders, J.5
Richardson, J.6
Littlewood, E.7
Myint, P.8
Newby, J.9
McKeith, I.G.10
-
240
-
-
0033591230
-
Cholesterol- dependent generation of a seeding amyloid beta-protein in cell culture
-
Mizuno, T., Nakata, M., Naiki, H., Michikawa, M., Wang, R., Haass, C. and Yanagisawa, K.: Cholesterol- dependent generation of a seeding amyloid beta-protein in cell culture. J. Biol. Chem. 274(21): 15110-15114, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.21
, pp. 15110-15114
-
-
Mizuno, T.1
Nakata, M.2
Naiki, H.3
Michikawa, M.4
Wang, R.5
Haass, C.6
Yanagisawa, K.7
-
241
-
-
0033525520
-
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain
-
Moechars, D., Dewachter, I., Lorent, K., Reverse, D., Baekelandt, V., Naidu, A., Tesseur, I., Spittaels, K., Haute, C. V., Checler, F., Godaux, E., Cordell, B. and Van Leuven, F.: Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. J. Biol. Chem. 274(10): 6483-6492, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.10
, pp. 6483-6492
-
-
Moechars, D.1
Dewachter, I.2
Lorent, K.3
Reverse, D.4
Baekelandt, V.5
Naidu, A.6
Tesseur, I.7
Spittaels, K.8
Haute, C.V.9
Checler, F.10
Godaux, E.11
Cordell, B.12
Van Leuven, F.13
-
242
-
-
0041886776
-
Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease
-
Monsonego, A., Zota, V., Karni, A., Krieger, J. I., Bar- Or, A., Bitan, G., Budson, A. E., Sperling, R., Selkoe, D. J. and Weiner, H. L.: Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease. J. Clin. Invest. 112(3): 415-422, 2003.
-
(2003)
J. Clin. Invest.
, vol.112
, Issue.3
, pp. 415-422
-
-
Monsonego, A.1
Zota, V.2
Karni, A.3
Krieger, J.I.4
Bar- Or, A.5
Bitan, G.6
Budson, A.E.7
Sperling, R.8
Selkoe, D.J.9
Weiner, H.L.10
-
243
-
-
0036043950
-
Fast axonal transport misregulation and Alzheimer's disease
-
Morfini, G., Pigino, G., Beffert, U., Busciglio, J. and Brady, S. T.: Fast axonal transport misregulation and Alzheimer's disease. Neuromolecular Med. 2(2): 89-99, 2002.
-
(2002)
Neuromolecular Med.
, vol.2
, Issue.2
, pp. 89-99
-
-
Morfini, G.1
Pigino, G.2
Beffert, U.3
Busciglio, J.4
Brady, S.T.5
-
244
-
-
0035997524
-
Intraneuronal Abeta42 accumulation in Down syndrome brain
-
Mori, C., Spooner, E. T., Wisniewsk, K. E., Wisniewski, T. M., Yamaguch, H., Saido, T. C., Tolan, D. R., Selkoe, D. J., Lemere, C. A.: Intraneuronal Abeta42 accumulation in Down syndrome brain. Amyloid. 9(2): 88-102, 2002.
-
(2002)
Amyloid.
, vol.9
, Issue.2
, pp. 88-102
-
-
Mori, C.1
Spooner, E.T.2
Wisniewsk, K.E.3
Wisniewski, T.M.4
Yamaguch, H.5
Saido, T.C.6
Tolan, D.R.7
Selkoe, D.J.8
Lemere, C.A.9
-
245
-
-
0027514286
-
Colocalization of cholinesterases with beta amyloid protein in aged and Alzheimer's brains
-
Moran, M. A., Mufson, E. J. and Gomez-Ramos, P.: Colocalization of cholinesterases with beta amyloid protein in aged and Alzheimer's brains. Acta Neuropathol. 85: 362-369, 1993.
-
(1993)
Acta Neuropathol.
, vol.85
, pp. 362-369
-
-
Moran, M.A.1
Mufson, E.J.2
Gomez-Ramos, P.3
-
246
-
-
0038632272
-
Learning and memory deficits in APP transgenic mouse models of amyloid deposition
-
Morgan, D.: Learning and memory deficits in APP transgenic mouse models of amyloid deposition. Neurochem. Res. 28(7): 1029-1034, 2003.
-
(2003)
Neurochem. Res.
, vol.28
, Issue.7
, pp. 1029-1034
-
-
Morgan, D.1
-
247
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan, D., Diamond, D. M., Gottschall, P. E., Ugen, K. E., Dickey, C., Hardy, J., Duff, K., Jantzen, P., DiCarlo, G., Wilcox, D., Connor, K., Hatcher, J., Hope, C., Gordon, M. and Arendash, G. W.: A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408(6815): 982-985, 2000.
-
(2000)
Nature
, vol.408
, Issue.6815
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
Duff, K.7
Jantzen, P.8
DiCarlo, G.9
Wilcox, D.10
Connor, K.11
Hatcher, J.12
Hope, C.13
Gordon, M.14
Arendash, G.W.15
-
248
-
-
0032480771
-
The presence of amyloid beta-protein in the detergent-insoluble membrane compartment of human neuroblastoma cells
-
Morishima-Kawashima, M. and Ihara, Y.: The presence of amyloid beta-protein in the detergent-insoluble membrane compartment of human neuroblastoma cells. Biochemistry 37(44): 15247-15253, 1998.
-
(1998)
Biochemistry
, vol.37
, Issue.44
, pp. 15247-15253
-
-
Morishima-Kawashima, M.1
Ihara, Y.2
-
249
-
-
0037177892
-
Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4
-
Morohashi, Y., Hatano, N., Ohya, S., Takikawa, R., Watabiki, T., Takasugi, N., Imaizumi, Y., Tomita, T. and Iwatsubo, T.: Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4. J. Biol. Chem. 277(17): 14965-14975, 2002.
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.17
, pp. 14965-14975
-
-
Morohashi, Y.1
Hatano, N.2
Ohya, S.3
Takikawa, R.4
Watabiki, T.5
Takasugi, N.6
Imaizumi, Y.7
Tomita, T.8
Iwatsubo, T.9
-
250
-
-
0035168927
-
Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease
-
Morris, J. C. and Price, A L.: Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease. J. Mol. Neurosci. 17(2): 101-118, 2001.
-
(2001)
J. Mol. Neurosci.
, vol.17
, Issue.2
, pp. 101-118
-
-
Morris, J.C.1
Price, A.L.2
-
252
-
-
0035879075
-
Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogenactivated protein kinase and c-Jun terminal kinase
-
Mudher, A., Chapman, S., Richardson, J., Asuni, A., Gibb, G., Pollard, C., Killick, R., Iqbal, T., Raymond, L., Varndell, I., Sheppard, P., Makoff, A., Gower, E., Soden, P. E., Lewis, P., Murphy, M., Golde, T. E., Rupniak, H. T., Anderton, B. H. and Lovestone, S.: Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogenactivated protein kinase and c-Jun terminal kinase. J. Neurosci. 21(14): 4987-4995, 2001.
-
(2001)
J. Neurosci.
, vol.21
, Issue.14
, pp. 4987-4995
-
-
Mudher, A.1
Chapman, S.2
Richardson, J.3
Asuni, A.4
Gibb, G.5
Pollard, C.6
Killick, R.7
Iqbal, T.8
Raymond, L.9
Varndell, I.10
Sheppard, P.11
Makoff, A.12
Gower, E.13
Soden, P.E.14
Lewis, P.15
Murphy, M.16
Golde, T.E.17
Rupniak, H.T.18
Anderton, B.H.19
Lovestone, S.20
more..
-
253
-
-
0028232662
-
Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro
-
Nathan, B. P., Bellosta, S., Sanan, D. A., Weisgraber, K. H., Mahley, R. W. and Pitas, R. E.: Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro. Science 264(5160): 850-852, 1994.
-
(1994)
Science
, vol.264
, Issue.5160
, pp. 850-852
-
-
Nathan, B.P.1
Bellosta, S.2
Sanan, D.A.3
Weisgraber, K.H.4
Mahley, R.W.5
Pitas, R.E.6
-
254
-
-
0034704245
-
Identification of HE1 as the second gene of Niemann-Pick C disease
-
Naureckiene, S., Sleat, D. E., Lackland, H., Fensom, A., Vanier, M. T., Wattiaux, R., Jadot, M. and Lobel, P.: Identification of HE1 as the second gene of Niemann-Pick C disease. Science 290: 2298-2301, 2000.
-
(2000)
Science
, vol.290
, pp. 2298-2301
-
-
Naureckiene, S.1
Sleat, D.E.2
Lackland, H.3
Fensom, A.4
Vanier, M.T.5
Wattiaux, R.6
Jadot, M.7
Lobel, P.8
-
255
-
-
3543073059
-
-
Editorial: Do Alzheimer's drugs work? Editorial Desk, Section 4, April 11
-
New York Times, Editorial: Do Alzheimer's drugs work? Editorial Desk, Section 4, p. 10, April 11, 2004.
-
(2004)
New York Times
, pp. 10
-
-
-
256
-
-
0035486922
-
Mutations in the open reading frame of the beta-site APP cleaving enzyme (BACE) locus are not a common cause of Alzheimer's disease
-
Nicolaou, M., Song, Y. Q., Sato, C. A., Orlacchio, A., Kawarai, T., Medeiros, H., Liang, Y., Sorbi, S., Richard, E., Rogaev, E. I., Moliaka, Y., Bruni, A. C., Jorge, R., Percy, M., Duara, R., Farrer, L. A., St. George-Hyslop, P. and Rogaeva, E. A.: Mutations in the open reading frame of the beta-site APP cleaving enzyme (BACE) locus are not a common cause of Alzheimer's disease. Neurogenetics 3(4): 203-206, 2001.
-
(2001)
Neurogenetics
, vol.3
, Issue.4
, pp. 203-206
-
-
Nicolaou, M.1
Song, Y.Q.2
Sato, C.A.3
Orlacchio, A.4
Kawarai, T.5
Medeiros, H.6
Liang, Y.7
Sorbi, S.8
Richard, E.9
Rogaev, E.I.10
Moliaka, Y.11
Bruni, A.C.12
Jorge, R.13
Percy, M.14
Duara, R.15
Farrer, L.A.16
George-Hyslop, P.17
Rogaeva, E.A.18
-
257
-
-
0032905727
-
Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex
-
Nishimura, M., Yu, G., Levesque, G., Zhang, D. M., Ruel, L., Chen, F., Milman, P., Holmes, E., Liang, Y., Kawarai, T., Jo, E., Supala, A., Rogaeva, E., Xu, D. M., Janus, C., Levesque, L., Bi, Q., Duthie, M., Rozmahel, R., Mattila, K., Lannfelt, L., Westaway, D., Mount, H. T., Woodgett, J., St. George-Hyslop, P., et al. Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex. Nat. Med. 5(2): 164-169, 1999.
-
(1999)
Nat. Med.
, vol.5
, Issue.2
, pp. 164-169
-
-
Nishimura, M.1
Yu, G.2
Levesque, G.3
Zhang, D.M.4
Ruel, L.5
Chen, F.6
Milman, P.7
Holmes, E.8
Liang, Y.9
Kawarai, T.10
Jo, E.11
Supala, A.12
Rogaeva, E.13
Xu, D.M.14
Janus, C.15
Levesque, L.16
Bi, Q.17
Duthie, M.18
Rozmahel, R.19
Mattila, K.20
Lannfelt, L.21
Westaway, D.22
Mount, H.T.23
Woodgett, J.24
George-Hyslop, P.25
more..
-
258
-
-
0026476297
-
Release of amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
-
Nitsch, R. M., Slack, B. E., Wurtan, R. J. and Growdon, J. H.: Release of amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 258: 304-307, 1992.
-
(1992)
Science
, vol.258
, pp. 304-307
-
-
Nitsch, R.M.1
Slack, B.E.2
Wurtan, R.J.3
Growdon, J.H.4
-
259
-
-
0032105340
-
Muscarinic acetylcholine receptors activate the acetylcholinesterase gene promoter
-
Nitsch, R. M., Rossner, S. and Albrecht, C.: Muscarinic acetylcholine receptors activate the acetylcholinesterase gene promoter. J. Physiol. 25: 257-264, 1998.
-
(1998)
J. Physiol.
, vol.25
, pp. 257-264
-
-
Nitsch, R.M.1
Rossner, S.2
Albrecht, C.3
-
260
-
-
0038689162
-
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
-
Noble, W., Olm, V., Takata, K., Casey, E., Mary, O., Meyerson, J., Gaynor, K., LaFrancois, J., Wang, L., Kondo, T., Davies, P., Burns, M., Veeranna, Nixon, R., Dickson, D., Matsuoka, Y., Ahlijanian, M., Lau, L. F. and Duff, K.: Cdk5 is a key factor in tau aggregation and tangle formation in vivo. Neuron 38(4): 555-565, 2003.
-
(2003)
Neuron
, vol.38
, Issue.4
, pp. 555-565
-
-
Noble, W.1
Olm, V.2
Takata, K.3
Casey, E.4
Mary, O.5
Meyerson, J.6
Gaynor, K.7
LaFrancois, J.8
Wang, L.9
Kondo, T.10
Davies, P.11
Burns, M.12
Veeranna13
Nixon, R.14
Dickson, D.15
Matsuoka, Y.16
Ahlijanian, M.17
Lau, L.F.18
Duff, K.19
-
261
-
-
0001142454
-
The effect of cholinesterase inhibitors studied with brain imaging
-
E. Giacobini, Ed., Martin Dunitz, London
-
Nordberg, A.: The effect of cholinesterase inhibitors studied with brain imaging. In: "Cholinesterases and Cholinesterase Inhibitors, " E. Giacobini, Ed., pp. 237-247, Martin Dunitz, London, 2000.
-
(2000)
Cholinesterases and Cholinesterase Inhibitors
, pp. 237-247
-
-
Nordberg, A.1
-
262
-
-
0347510769
-
Toward an early diagnosis and treatment of Alzheimer's disease
-
Nordberg, A.: Toward an early diagnosis and treatment of Alzheimer's disease. Int. Psychogeriatr. 15: 223- 227, 2003.
-
(2003)
Int. Psychogeriatr.
, vol.15
, pp. 223-227
-
-
Nordberg, A.1
-
263
-
-
0344009739
-
Functional studies of cholinergic activity in normal and Alzheimer's disease states by imaging technique
-
Nordberg, A.: Functional studies of cholinergic activity in normal and Alzheimer's disease states by imaging technique. Prog. Brain Res. 145: 301-310, 2004.
-
(2004)
Prog. Brain Res.
, vol.145
, pp. 301-310
-
-
Nordberg, A.1
-
264
-
-
0002468232
-
Brain nicotinic and muscarinic receptors in normal aging and dementia
-
A. Fisher, I. Hanin, and C. Lachman, Eds., Plenum Press, New York
-
Nordberg, A. and Winblad, B.: Brain nicotinic and muscarinic receptors in normal aging and dementia. In: "Alzheimer's and Parkinson's Diseases, " A. Fisher, I. Hanin, and C. Lachman, Eds., pp. 95-108, Plenum Press, New York, 1986.
-
(1986)
Alzheimer's and Parkinson's Diseases
, pp. 95-108
-
-
Nordberg, A.1
Winblad, B.2
-
265
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
Oddo, S., Caccamo, A., Shepherd, J. D., Murphy, M. P., Golde, T. E., Kayed, R., Metherate, R., Mattson, M. P., Akbari, Y. and LaFerla, F. M.: Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction. Neuron 39(3): 409-421, 2003.
-
(2003)
Neuron
, vol.39
, Issue.3
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
266
-
-
0037313587
-
Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an apolipoprotein E receptor/disabled-1/glycogen synthase kinase-3beta cascade
-
Ohkubo, N., Lee, Y. D., Morishima, A., Terashima, T., Kikkawa, S., Tohyama, M., Sakanaka, M., Tanaka, J., Maeda, N., Vitek, M. P. and Mitsuda, N.: Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an apolipoprotein E receptor/disabled-1/glycogen synthase kinase-3beta cascade. FASEB J. 17(2): 295-297, 2003.
-
(2003)
FASEB J.
, vol.17
, Issue.2
, pp. 295-297
-
-
Ohkubo, N.1
Lee, Y.D.2
Morishima, A.3
Terashima, T.4
Kikkawa, S.5
Tohyama, M.6
Sakanaka, M.7
Tanaka, J.8
Maeda, N.9
Vitek, M.P.10
Mitsuda, N.11
-
267
-
-
0024426526
-
The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II
-
Oltersdorf, T., Fritz, L. C., Schenk, D. B., Lieberburg, I., Johnson-Wood, K. L., Beattie, E. C., Ward, P. J., Blacher, R. W., Dovey, H. F. and Sinha, S.: The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II. Nature 341(6238): 144-147, 1989.
-
(1989)
Nature
, vol.341
, Issue.6238
, pp. 144-147
-
-
Oltersdorf, T.1
Fritz, L.C.2
Schenk, D.B.3
Lieberburg, I.4
Johnson-Wood, K.L.5
Beattie, E.C.6
Ward, P.J.7
Blacher, R.W.8
Dovey, H.F.9
Sinha, S.10
-
268
-
-
0035230380
-
Dysfunctional intracellular calcium homoeostasis: A central cause of neurodegeneration in Alzheimer's disease
-
O'Neill, C., Cowburn, R. F., Bonkale, W. L., Ohm, T. G., Fastbom, J., Carmody, M. and Kelliher, M.: Dysfunctional intracellular calcium homoeostasis: A central cause of neurodegeneration in Alzheimer's disease. Biochem. Soc. Symp. 2001(67): 177-194, 2001.
-
(2001)
Biochem. Soc. Symp.
, vol.2001
, Issue.67
, pp. 177-194
-
-
O'Neill, C.1
Cowburn, R.F.2
Bonkale, W.L.3
Ohm, T.G.4
Fastbom, J.5
Carmody, M.6
Kelliher, M.7
-
269
-
-
4243072970
-
ITH4012 (ethyl 5-amino-6, 7, 8, 9-tetrahydro- 2-methyl-4-phenylbenzol(1, 8) naphtythyridine-3- carboxylate. A novel acetylcholinesterase inhibitor with "calcium-promotor" and neuroprotective properties
-
Orozco, C., de Los Rios, C., Arias, E., Leon R. Garcia, A. G., Marco, J. L., Villarroya, M. and Lopez, M. G.: ITH4012 (ethyl 5-amino-6, 7, 8, 9-tetrahydro- 2-methyl-4-phenylbenzol(1, 8) naphtythyridine-3- carboxylate. a novel acetylcholinesterase inhibitor with "calcium-promotor" and neuroprotective properties. J. Pharmacol. Exper. Therap. 310: 987-994, 2004.
-
(2004)
J. Pharmacol. Exper. Therap.
, vol.310
, pp. 987-994
-
-
Orozco, C.1
De Los Rios, C.2
Arias, E.3
Leon R. Garcia, A.G.4
Marco, J.L.5
Villarroya, M.6
Lopez, M.G.7
-
270
-
-
18544411933
-
Mutant presenilin 2 transgenic mouse: Effect on an age-dependent increase of amyloid betaprotein 42 in the brain
-
Oyama, F., Sawamura, N., Kobayashi, K., Morishima- Kawashima, M., Kuramochi, T., Ito, M., Tomita, T., Maruyama, K., Saido, T. C., Iwatsubo, T., Capell, A., Walter, J., Grunberg, J., Ueyama, Y., Haass, C. and Ihara, Y.: Mutant presenilin 2 transgenic mouse: Effect on an age-dependent increase of amyloid betaprotein 42 in the brain. J. Neurochem. 71(1): 313- 322, 1998.
-
(1998)
J. Neurochem.
, vol.71
, Issue.1
, pp. 313-322
-
-
Oyama, F.1
Sawamura, N.2
Kobayashi, K.3
Morishima-Kawashima, M.4
Kuramochi, T.5
Ito, M.6
Tomita, T.7
Maruyama, K.8
Saido, T.C.9
Iwatsubo, T.10
Capell, A.11
Walter, J.12
Grunberg, J.13
Ueyama, Y.14
Haass, C.15
Ihara, Y.16
-
271
-
-
0034724977
-
In vitro effects of metrifonate on neuronal precursor protein processing and protein kinase C level
-
Pakaski, M., Rakonczay, Z., Fakla, I., Papp, H. and Kasa, P.: In vitro effects of metrifonate on neuronal precursor protein processing and protein kinase C level. Brain Res. 863: 266-270, 2000.
-
(2000)
Brain Res.
, vol.863
, pp. 266-270
-
-
Pakaski, M.1
Rakonczay, Z.2
Fakla, I.3
Papp, H.4
Kasa, P.5
-
272
-
-
0024793425
-
The beta amyloid protein precursor: MRNAs, membrane-associated forms, and soluble derivatives
-
Palmert, M. R., Podlisny, M. B., Golde, T. E., Cohen, M. L., Kovacs, D. M., Tanzi, R. E., Gusella, J. F., Whitehouse, P. J., Witker, D. S., Oltersdorf, T., et al.: The beta amyloid protein precursor: mRNAs, membrane-associated forms, and soluble derivatives. Prog. Clin. Biol. Res. 317: 971-984, 1989.
-
(1989)
Prog. Clin. Biol. Res.
, vol.317
, pp. 971-984
-
-
Palmert, M.R.1
Podlisny, M.B.2
Golde, T.E.3
Cohen, M.L.4
Kovacs, D.M.5
Tanzi, R.E.6
Gusella, J.F.7
Whitehouse, P.J.8
Witker, D.S.9
Oltersdorf, T.10
-
273
-
-
0042924399
-
Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits
-
Palop, J. J., Jones, B., Kekonius, L., Chin, J., Yu, G. Q., Raber, J., Masliah, E. and Mucke, L.: Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits. Proc. Natl. Acad. Sci. U.S.A. 100(16): 9572-9577, 2003.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, Issue.16
, pp. 9572-9577
-
-
Palop, J.J.1
Jones, B.2
Kekonius, L.3
Chin, J.4
Yu, G.Q.5
Raber, J.6
Masliah, E.7
Mucke, L.8
-
274
-
-
0032493729
-
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway
-
Pap, M. and Cooper, G. M.: Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway. J. Biol. Chem. 273(32): 19929-19932, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.32
, pp. 19929-19932
-
-
Pap, M.1
Cooper, G.M.2
-
275
-
-
0036883539
-
Presenilin-1 and the amyloid precursor protein are transported bidirectionally in the sciatic nerve of adult rat
-
Papp, H., Pakaski, M., Kasa, P.: Presenilin-1 and the amyloid precursor protein are transported bidirectionally in the sciatic nerve of adult rat. Neurochem. Int. 41(6): 429-435, 2002.
-
(2002)
Neurochem. Int.
, vol.41
, Issue.6
, pp. 429-435
-
-
Papp, H.1
Pakaski, M.2
Kasa, P.3
-
276
-
-
0033571721
-
Amyloid precursor protein, although partially detergentinsoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein
-
Parkin, E. T., Turner, A. J. and Hooper, N. M.: Amyloid precursor protein, although partially detergentinsoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein. Biochem. J. 344, Pt. 1: 23-30, 1999.
-
(1999)
Biochem. J.
, vol.344
, pp. 23-30
-
-
Parkin, E.T.1
Turner, A.J.2
Hooper, N.M.3
-
277
-
-
0037698096
-
Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are colocalized in the lysosomal membrane
-
Pasternak, S. H., Bagshaw, R. D., Guiral, M., Zhang, S., Ackerley, C. A., Pak, B. J., Callahan, J. W. and Mahuran, D. J.: Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are colocalized in the lysosomal membrane. J. Biol. Chem. 278(29): 26687-26694, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.29
, pp. 26687-26694
-
-
Pasternak, S.H.1
Bagshaw, R.D.2
Guiral, M.3
Zhang, S.4
Ackerley, C.A.5
Pak, B.J.6
Callahan, J.W.7
Mahuran, D.J.8
-
278
-
-
0033540060
-
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
-
Patrick, G. N., Zukerberg, L., Nikolic, M., de la Monte, S., Dikkes, P. and Tsai, L. H.: Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 402(6762): 615-622, 1999.
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 615-622
-
-
Patrick, G.N.1
Zukerberg, L.2
Nikolic, M.3
De La Monte, S.4
Dikkes, P.5
Tsai, L.H.6
-
279
-
-
0032850599
-
Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes
-
Pei, J. J., Braak, E., Braak, H., Grundke-Iqbal, I., Iqbal, K., Winblad, B. and Cowburn, R. F.: Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes. J. Neuropathol. Exp. Neurol. 58(9): 1010-1019, 1999.
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, Issue.9
, pp. 1010-1019
-
-
Pei, J.J.1
Braak, E.2
Braak, H.3
Grundke-Iqbal, I.4
Iqbal, K.5
Winblad, B.6
Cowburn, R.F.7
-
280
-
-
0038100358
-
Role of protein kinase B in Alzheimer's neurofibrillary pathology
-
Pei, J. J., Khatoon, S., An, W. L., Nordlinder, M., Tanaka, T., Braak, H., Tsujio, I., Takeda, M., Alafuzoff, I., Winblad, B., Cowburn, R. F., Grundke- Iqbal, I. and Iqbal, K.: Role of protein kinase B in Alzheimer's neurofibrillary pathology. Acta Neuropathol. (Berl.) 105(4): 381-392, 2003.
-
(2003)
Acta Neuropathol. (Berl.)
, vol.105
, Issue.4
, pp. 381-392
-
-
Pei, J.J.1
Khatoon, S.2
An, W.L.3
Nordlinder, M.4
Tanaka, T.5
Braak, H.6
Tsujio, I.7
Takeda, M.8
Alafuzoff, I.9
Winblad, B.10
Cowburn, R.F.11
Grundke- Iqbal, I.12
Iqbal, K.13
-
281
-
-
12344306018
-
Characterization of a double (amyloid precursor proteintau) transgenic: Tau phosphorylation and aggregation
-
Perez, M., Ribe, E., Rubio, A., Lim, F., et al.: Characterization of a double (amyloid precursor proteintau) transgenic: Tau phosphorylation and aggregation. Neuroscience 130: 339-347, 2005.
-
(2005)
Neuroscience
, vol.130
, pp. 339-347
-
-
Perez, M.1
Ribe, E.2
Rubio, A.3
Lim, F.4
-
282
-
-
84886631402
-
Neurotransmitter enzyme abnormalities in senile dementia
-
Perry, E. K., Gibson, P. H., Blessed, G., Perry, R. H. and Tomlison, B. E.: Neurotransmitter enzyme abnormalities in senile dementia. J. Neurol. Sci. 34: 247- 265, 1977.
-
(1977)
J. Neurol. Sci.
, vol.34
, pp. 247-265
-
-
Perry, E.K.1
Gibson, P.H.2
Blessed, G.3
Perry, R.H.4
Tomlison, B.E.5
-
283
-
-
11444268288
-
Absence of cholinergic deficits in "pure" vascular dementia
-
Perry, E. K., Ziabreva, I., Perry, R. H., Aarsland, D. and Ballard, C.: Absence of cholinergic deficits in "pure" vascular dementia. Neurology 64: 132-133, 2005.
-
(2005)
Neurology
, vol.64
, pp. 132-133
-
-
Perry, E.K.1
Ziabreva, I.2
Perry, R.H.3
Aarsland, D.4
Ballard, C.5
-
284
-
-
0000381003
-
Über klinisch und histologisch eigenmartige psychische Erkränkung der späteren Lebensalters
-
F. Nissl and A. Alzheimer, Eds. Bd
-
Perusini, G.: Über klinisch und histologisch eigenmartige psychische Erkränkung der späteren Lebensalters. In: "Histologische und Histopataologische Arbeiten, " F. Nissl and A. Alzheimer, Eds., Bd. 3, pp. 197-351, 1910.
-
(1910)
Histologische Und Histopataologische Arbeiten
, vol.3
, pp. 197-351
-
-
Perusini, G.1
-
285
-
-
0344246544
-
Sul valore nosografico di alcuni reperti istopatologici caractteristici per la senilita
-
Perusini, G.: Sul valore nosografico di alcuni reperti istopatologici caractteristici per la senilita. Revista Ital. Neuropatol. Psichiat. Elettroter. 4: 145-151, 1911.
-
(1911)
Revista Ital. Neuropatol. Psichiat. Elettroter.
, vol.4
, pp. 145-151
-
-
Perusini, G.1
-
286
-
-
0018319269
-
Effects of physostigmine and lecithin on memory in Alzheimer's disease
-
Peters, B. and Levin, H. S.: Effects of physostigmine and lecithin on memory in Alzheimer's disease. Ann. Neurol. 6: 219-221, 1979.
-
(1979)
Ann. Neurol.
, vol.6
, pp. 219-221
-
-
Peters, B.1
Levin, H.S.2
-
287
-
-
0037062566
-
Cerebral amyloid angiopathy and cognitive function: The HAAS autopsy study
-
Pfeifer, L. A., White, L. R., Ross, G. W., Petrovitch, H. and Launer, L. J.: Cerebral amyloid angiopathy and cognitive function: The HAAS autopsy study. Neurology 58(11): 1629-1634, 2002a.
-
(2002)
Neurology
, vol.58
, Issue.11
, pp. 1629-1634
-
-
Pfeifer, L.A.1
White, L.R.2
Ross, G.W.3
Petrovitch, H.4
Launer, L.J.5
-
288
-
-
0037112201
-
Cerebral hemorrhage after passive anti- Abeta immunotherapy
-
Pfeifer, M., Boncristiano, S., Bondolfi, L., Stalder, A., Deller, T., Staufenbiel, M., Mathews, P. M. and Jucker, M.: Cerebral hemorrhage after passive anti- Abeta immunotherapy. Science 298(5597): 1379, 2002b.
-
(2002)
Science
, vol.298
, Issue.5597
, pp. 1379
-
-
Pfeifer, M.1
Boncristiano, S.2
Bondolfi, L.3
Stalder, A.4
Deller, T.5
Staufenbiel, M.6
Mathews, P.M.7
Jucker, M.8
-
289
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
Phiel, C. J., Wilson, C. A., Lee, V. M. and Klein, P. S.: GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 423(6938): 435-439, 2003.
-
(2003)
Nature
, vol.423
, Issue.6938
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.3
Klein, P.S.4
-
290
-
-
26644445247
-
β-Amyloid is different in normal aging and in Alzheimer disease
-
Piccini, A., Russo, C., Gliozzi, A., Relini, A., et al.: β-Amyloid is different in normal aging and in Alzheimer disease. J. Biol. Chem. 280: 34186-34192, 2005.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 34186-34192
-
-
Piccini, A.1
Russo, C.2
Gliozzi, A.3
Relini, A.4
-
291
-
-
0038118207
-
Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport
-
Pigino, G., Morfini, G., Pelsman, A., Mattson, M. P., Brady, S. T. and Busciglio, J.: Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport. J. Neurosci. 23(11): 4499-4508, 2003.
-
(2003)
J. Neurosci.
, vol.23
, Issue.11
, pp. 4499-4508
-
-
Pigino, G.1
Morfini, G.2
Pelsman, A.3
Mattson, M.P.4
Brady, S.T.5
Busciglio, J.6
-
292
-
-
0032575524
-
Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover
-
Pike, L. J. and Miller, J. M.: Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover. J. Biol. Chem. 273(35): 22298-22304, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.35
, pp. 22298-22304
-
-
Pike, L.J.1
Miller, J.M.2
-
293
-
-
0034515763
-
Apolipoprotein E and Alzheimer's disease: A role in amyloid catabolism
-
Poirier, J.: Apolipoprotein E and Alzheimer's disease: A role in amyloid catabolism. Ann N. Y. Acad. Sci. 924: 81-90, 2000.
-
(2000)
Ann N. Y. Acad. Sci.
, vol.924
, pp. 81-90
-
-
Poirier, J.1
-
294
-
-
0027298061
-
Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats
-
Poirier, J., Baccichet, A., Dea, D. and Gauthier, S.: Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats. Neuroscience 55(1): 81-90, 1993.
-
(1993)
Neuroscience
, vol.55
, Issue.1
, pp. 81-90
-
-
Poirier, J.1
Baccichet, A.2
Dea, D.3
Gauthier, S.4
-
296
-
-
0023870043
-
A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors
-
Ponte, P., Gonzalez-DeWhitt, P., Schilling, J., Miller, J., Hsu, D., Greenberg, B., Davis, K., Wallace, W., Lieberburg, I. and Fuller, F.: A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature 331(6156): 525-527, 1988.
-
(1988)
Nature
, vol.331
, Issue.6156
, pp. 525-527
-
-
Ponte, P.1
Gonzalez-DeWhitt, P.2
Schilling, J.3
Miller, J.4
Hsu, D.5
Greenberg, B.6
Davis, K.7
Wallace, W.8
Lieberburg, I.9
Fuller, F.10
-
297
-
-
84920034597
-
The Macaca mulatta model of Alzheimer's disease
-
Price, D. L.: The Macaca mulatta model of Alzheimer's disease. Neurosci. Facts 4: 17-18, 1993.
-
(1993)
Neurosci. Facts
, vol.4
, pp. 17-18
-
-
Price, D.L.1
-
298
-
-
0344629364
-
Pharmacologic management of agitation in Alzheimer's disease
-
Profenno, L. A. and Tariot, P. N.: Pharmacologic management of agitation in Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 17: 65-77, 2005.
-
(2005)
Dement. Geriatr. Cogn. Disord.
, vol.17
, pp. 65-77
-
-
Profenno, L.A.1
Tariot, P.N.2
-
299
-
-
0034795651
-
Acyl-coenzyme A: Cholesterol acyltransferase modulates the generation of the amyloid beta-peptide
-
Puglielli, L., Konopka, G., Pack-Chung, E., Ingano, L. A., Berezovska, O., Hyman, B. T., Chang, T. Y., Tanzi, R. E. and Kovacs, D. M.: Acyl-coenzyme A: Cholesterol acyltransferase modulates the generation of the amyloid beta-peptide. Nat. Cell Biol. 3(10): 905-912, 2001.
-
(2001)
Nat. Cell Biol.
, vol.3
, Issue.10
, pp. 905-912
-
-
Puglielli, L.1
Konopka, G.2
Pack-Chung, E.3
Ingano, L.A.4
Berezovska, O.5
Hyman, B.T.6
Chang, T.Y.7
Tanzi, R.E.8
Kovacs, D.M.9
-
300
-
-
0027324122
-
Induction of apoptosis by low-affinity NGF receptor
-
Rabidazeh, S., Oh, S., Ord, J., Zhong, L.-T., Yang, J., Bittner, C. M., Butcher, L. L. and Dresdesen, D. E.: Induction of apoptosis by low-affinity NGF receptor. Science 261: 345-348, 1993.
-
(1993)
Science
, vol.261
, pp. 345-348
-
-
Rabidazeh, S.1
Oh, S.2
Ord, J.3
Zhong, L.-T.4
Yang, J.5
Bittner, C.M.6
Butcher, L.L.7
Dresdesen, D.E.8
-
301
-
-
0027996904
-
Expression of the low affinity growth factor receptor enhances beta-amyloid peptide toxicity
-
Rabizadeh, S., Bittner, C. M., Butcher, L. L. and Bredesen, D. E.: Expression of the low affinity growth factor receptor enhances beta-amyloid peptide toxicity. Proc. Natl. Acad. Sci. U.S.A. 91: 10703-10706, 1994.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 10703-10706
-
-
Rabizadeh, S.1
Bittner, C.M.2
Butcher, L.L.3
Bredesen, D.E.4
-
302
-
-
17644429206
-
Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content
-
Racchi, M., Baetta, R., Salvietti, N., Ianna, P., Franceschini, G., Paoletti, R., Fumagalli, R., Govoni, S., Trabucchi, M. and Soma, M.: Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content. Biochem. J. 322, Pt. 3: 893-898, 1997.
-
(1997)
Biochem. J
, vol.322
, pp. 893-898
-
-
Racchi, M.1
Baetta, R.2
Salvietti, N.3
Ianna, P.4
Franceschini, G.5
Paoletti, R.6
Fumagalli, R.7
Govoni, S.8
Trabucchi, M.9
Soma, M.10
-
303
-
-
0010665141
-
Über miliare Sklerose der Hirnrinde bei seniler Atrophie
-
Redlich, E.: Über miliare Sklerose der Hirnrinde bei seniler Atrophie. Jahrbuche Psych. u. Neurol. 17: 361-372, 1898.
-
(1898)
Jahrbuche Psych. U. Neurol.
, vol.17
, pp. 361-372
-
-
Redlich, E.1
-
304
-
-
17344388652
-
BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: Implications for Alzheimer's disease therapeutics
-
Roberds, S. L., Anderson, J., Basi, G., Bienkowski, M. J., Branstetter, D. G., Chen, K. S., Freedman, S. B., Frigon, N. L., Games, D., Hu, K., Johnson-Wood, K., Kappenman, K. E., Kawabe, T. T., Kola, I., Kuehn, R., Lee, M., Liu, W., Motter, R., Nichols, N. F., Power, M., Robertson, D. W., Schenk, D., Schoor, M., Shopp, G. M., Shuck, M. E., Sinha, S., Svensson, K. A., Tatsuno, G., Tintrup, H., Wijsman, J., Wright, S. and McConlogue, L.: BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: Implications for Alzheimer's disease therapeutics. Hum. Mol. Genet. 10(12): 1317-1324, 2001.
-
(2001)
Hum. Mol. Genet.
, vol.10
, Issue.12
, pp. 1317-1324
-
-
Roberds, S.L.1
Anderson, J.2
Basi, G.3
Bienkowski, M.J.4
Branstetter, D.G.5
Chen, K.S.6
Freedman, S.B.7
Frigon, N.L.8
Games, D.9
Hu, K.10
Johnson-Wood, K.11
Kappenman, K.E.12
Kawabe, T.T.13
Kola, I.14
Kuehn, R.15
Lee, M.16
Liu, W.17
Motter, R.18
Nichols, N.F.19
Power, M.20
Robertson, D.W.21
Schenk, D.22
Schoor, M.23
Shopp, G.M.24
Shuck, M.E.25
Sinha, S.26
Svensson, K.A.27
Tatsuno, G.28
Tintrup, H.29
Wijsman, J.30
Wright, S.31
McConlogue, L.32
more..
-
305
-
-
0032931988
-
Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
-
Rodal, S. K., Skretting, G., Garred, O., Vilhardt, F., van Deurs, B. and Sandvig, K.: Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles. Mol. Biol. Cell. 10(4): 961-974, 1999.
-
(1999)
Mol. Biol. Cell.
, vol.10
, Issue.4
, pp. 961-974
-
-
Rodal, S.K.1
Skretting, G.2
Garred, O.3
Vilhardt, F.4
Van Deurs, B.5
Sandvig, K.6
-
306
-
-
0141954291
-
The neuropharmacological basis for the use of memantine in treatment of Alzheimer's disease
-
Rogawski, M. A. and Wenk, G. L.: The neuropharmacological basis for the use of memantine in treatment of Alzheimer's disease. CNS Drug Rev. 9(3): 275- 308, 2003.
-
(2003)
CNS Drug Rev.
, vol.9
, Issue.3
, pp. 275-308
-
-
Rogawski, M.A.1
Wenk, G.L.2
-
307
-
-
0009631131
-
Cell-specific expression of beta-amyloid precursor protein isoform mRNAs and proteins in neurons and astrocytes
-
Rohan de Silva, H. A., Jen, A., Wickenden, C., Jen, L. S., Wilkinson, S. L. and Patel, A. J.: Cell-specific expression of beta-amyloid precursor protein isoform mRNAs and proteins in neurons and astrocytes. Brain Res. Mol. Brain Res. 47(1-2): 147-156, 1997.
-
(1997)
Brain Res. Mol. Brain Res.
, vol.47
, Issue.1-2
, pp. 147-156
-
-
Rohan De Silva, H.A.1
Jen, A.2
Wickenden, C.3
Jen, L.S.4
Wilkinson, S.L.5
Patel, A.J.6
-
308
-
-
0029263413
-
Influence of the susceptibility genes apolipoprotein Eepsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease
-
Roses, A. D., Saunders, A. M., Corder, E. H., Pericak- Vance, M. A., Han, S. H., Einstein, G., Hulette, C., Schmechel, D. E., Holsti, M., Huang, D., et al.: Influence of the susceptibility genes apolipoprotein Eepsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease. Arzneimittelforschung. 45(3A): 413-417, 1995.
-
(1995)
Arzneimittelforschung
, vol.45
, Issue.3 A
, pp. 413-417
-
-
Roses, A.D.1
Saunders, A.M.2
Corder, E.H.3
Pericak- Vance, M.A.4
Han, S.H.5
Einstein, G.6
Hulette, C.7
Schmechel, D.E.8
Holsti, M.9
Huang, D.10
-
309
-
-
0001059974
-
The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling
-
Rossner, S., Ueberham, U., Schliebs, R., Perez-Polo, J. R. and Bigl, V.: The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling. Prog. Neurobiol. 56(5): 541-569, 1998.
-
(1998)
Prog. Neurobiol.
, vol.56
, Issue.5
, pp. 541-569
-
-
Rossner, S.1
Ueberham, U.2
Schliebs, R.3
Perez-Polo, J.R.4
Bigl, V.5
-
310
-
-
0030017123
-
Live long and prosper?
-
Roush, W.: Live long and prosper? Science 273: 42-46, 1996.
-
(1996)
Science
, vol.273
, pp. 42-46
-
-
Roush, W.1
-
311
-
-
0036523031
-
Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells
-
Runz, H., Rietdorf, J., Tomic, I., de Bernard, M., Beyreuther, K., Pepperkok, R. and Hartmann, T.: Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells. J. Neurosci. 22(5): 1679-1689, 2002.
-
(2002)
J. Neurosci.
, vol.22
, Issue.5
, pp. 1679-1689
-
-
Runz, H.1
Rietdorf, J.2
Tomic, I.3
De Bernard, M.4
Beyreuther, K.5
Pepperkok, R.6
Hartmann, T.7
-
312
-
-
0024250449
-
Brain "transplants, " neurotrophic factors and behavior
-
Russell, R. W.: Brain "transplants, " neurotrophic factors and behavior. Alzheimer Dis. Assoc. Disord. 2: 77- 95, 1988.
-
(1988)
Alzheimer Dis. Assoc. Disord.
, vol.2
, pp. 77-95
-
-
Russell, R.W.1
-
313
-
-
18744435477
-
Presenilin-1 mutations in Alzheimer's disease
-
Russo, C., Schettini, G., Saido, T. C., Hulette, C., Lippa, C., Lannfelt, L., Ghetti, B., Gambetti, P., Tabaton, M., Teller, J. K.: Presenilin-1 mutations in Alzheimer's disease. Nature 405(6786): 531-532, 2000.
-
(2000)
Nature
, vol.405
, Issue.6786
, pp. 531-532
-
-
Russo, C.1
Schettini, G.2
Saido, T.C.3
Hulette, C.4
Lippa, C.5
Lannfelt, L.6
Ghetti, B.7
Gambetti, P.8
Tabaton, M.9
Teller, J.K.10
-
314
-
-
0038795608
-
An autocatalytic reaction as a model for the kinetics of the aggregation of beta-amyloid
-
Sabate, R., Gallardo, M. and Estelrich, J.: An autocatalytic reaction as a model for the kinetics of the aggregation of beta-amyloid. Biopolymers 71(2): 190-195, 2003.
-
(2003)
Biopolymers
, vol.71
, Issue.2
, pp. 190-195
-
-
Sabate, R.1
Gallardo, M.2
Estelrich, J.3
-
315
-
-
4444242307
-
L6 myoblast differentiation is modulated by Cdk5 via the PI3K-Akt-p70s6K signaling pathway
-
Sarker, K. P. and Lee, K. Y.: L6 myoblast differentiation is modulated by Cdk5 via the PI3K-Akt-p70s6K signaling pathway, Oncogene. 23: 6064, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 6064
-
-
Sarker, K.P.1
Lee, K.Y.2
-
316
-
-
0033795279
-
Apolipoprotein E and Alzheimer disease: An update on genetic and functional analyses
-
Saunders, A. M.: Apolipoprotein E and Alzheimer disease: An update on genetic and functional analyses. J. Neuropathol. Exp. Neurol. 59(9): 751-758, 2000.
-
(2000)
J. Neuropathol. Exp. Neurol.
, vol.59
, Issue.9
, pp. 751-758
-
-
Saunders, A.M.1
-
317
-
-
0035971218
-
Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice
-
Sawamura, N., Gong, J. S., Garver, W. S., Heidenreich, R. A., Ninomiya, H., Ohno, K., Yanagisawa, K. and Michikawa, M.: Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice. J. Biol. Chem. 276: 10314-10319, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 10314-10319
-
-
Sawamura, N.1
Gong, J.S.2
Garver, W.S.3
Heidenreich, R.A.4
Ninomiya, H.5
Ohno, K.6
Yanagisawa, K.7
Michikawa, M.8
-
318
-
-
0037162094
-
Regulation of neuronal cytoskeleton by lysophosphatidic acid: Role of GSK-3
-
Sayas, C. L., Avila, J. and Wandosell, F.: Regulation of neuronal cytoskeleton by lysophosphatidic acid: Role of GSK-3. Biochim. Biophys. Acta 1582(1-3): 144- 153, 2002.
-
(2002)
Biochim. Biophys. Acta
, vol.1582
, Issue.1-3
, pp. 144-153
-
-
Sayas, C.L.1
Avila, J.2
Wandosell, F.3
-
319
-
-
3142547230
-
Cholinergic enhancement of frontal lobe activity in mild cognitive impairment
-
Saykin, A. J., Wishart, H. A., Rabin, L. A., Flashmen, L. A., McHugh, T. L., Mamot, A. C. and Santulli, R. B.: Cholinergic enhancement of frontal lobe activity in mild cognitive impairment. Brain 127: 1574-1583, 2004.
-
(2004)
Brain
, vol.127
, pp. 1574-1583
-
-
Saykin, A.J.1
Wishart, H.A.2
Rabin, L.A.3
Flashmen, L.A.4
McHugh, T.L.5
Mamot, A.C.6
Santulli, R.B.7
-
320
-
-
0031754362
-
Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal segment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease
-
Sberna, G., Saez-Valero, J. and Li, Q.-X.: Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal segment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease. J. Neurochem. 71: 723-731, 1998.
-
(1998)
J. Neurochem.
, vol.71
, pp. 723-731
-
-
Sberna, G.1
Saez-Valero, J.2
Li, Q.-X.3
-
321
-
-
0036780877
-
Amyloid-beta immunotherapy for Alzheimer's disease: The end of the beginning
-
Schenk, D.: Amyloid-beta immunotherapy for Alzheimer's disease: The end of the beginning. Nat. Rev. Neurosci. 3(10): 824-828, 2002.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, Issue.10
, pp. 824-828
-
-
Schenk, D.1
-
322
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner, D., Eckman, C., Jensen, M., Song, X., Citron, M., Suzuki, N., Bird, T. D., Hardy, J., Hutton, M., Kukull, W., Larson, E., Levy-Lahad, E., Viitanen, M., Peskind, E., Poorkaj, P., Schellenberg, G., Tanzi, R., Wasco, W., Lannfelt, L., Selkoe, D. and Younkin, S.: Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2(8): 864-870, 1996.
-
(1996)
Nat. Med.
, vol.2
, Issue.8
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
323
-
-
0027517128
-
Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of coagulation factor IXa
-
Schmaier, A. H., Dahl, L. D., Rozemuller, A. J., Roos, R. A., Wagner, S. L., Chung, R. and Van Nostrand, W. E.: Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of coagulation factor IXa. J. Clin. Invest. 92(5): 2540-2545, 1993.
-
(1993)
J. Clin. Invest.
, vol.92
, Issue.5
, pp. 2540-2545
-
-
Schmaier, A.H.1
Dahl, L.D.2
Rozemuller, A.J.3
Roos, R.A.4
Wagner, S.L.5
Chung, R.6
Van Nostrand, W.E.7
-
324
-
-
0035853828
-
Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation
-
Schneider, I., Reverse, D., Dewachter, I., Ris, L., Caluwaerts, N., Kuiperi, C., Gilis, M., Geerts, H., Kretzschmar, H., Godaux, E., Moechars, D., Van Leuven, F. and Herms, J.: Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation. J. Biol. Chem. 276(15): 11539-11544, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.15
, pp. 11539-11544
-
-
Schneider, I.1
Reverse, D.2
Dewachter, I.3
Ris, L.4
Caluwaerts, N.5
Kuiperi, C.6
Gilis, M.7
Geerts, H.8
Kretzschmar, H.9
Godaux, E.10
Moechars, D.11
Van Leuven, F.12
Herms, J.13
-
325
-
-
0025886677
-
Transmembrane distribution of sterol in the human erythrocyte
-
Schroeder, F., Nemecz, G., Wood, W. G., Joiner, C., Morrot, G., Ayraut-Jarrier, M. and Devaux, P. F.: Transmembrane distribution of sterol in the human erythrocyte. Biochim. Biophys. Acta 1066(2): 183- 192, 1991.
-
(1991)
Biochim. Biophys. Acta
, vol.1066
, Issue.2
, pp. 183-192
-
-
Schroeder, F.1
Nemecz, G.2
Wood, W.G.3
Joiner, C.4
Morrot, G.5
Ayraut-Jarrier, M.6
Devaux, P.F.7
-
326
-
-
0032933457
-
Secretion of protease nexin-II/amyloid beta protein precursor by human colorectal carcinoma cells and its modulation by cytokines/growth factors and proteinase inhibitors
-
Seguchi, K., Kataoka, H., Uchino, H., Nabeshima, K. and Koono, M.: Secretion of protease nexin-II/amyloid beta protein precursor by human colorectal carcinoma cells and its modulation by cytokines/growth factors and proteinase inhibitors. Biol. Chem. 380(4): 473-483, 1999.
-
(1999)
Biol. Chem.
, vol.380
, Issue.4
, pp. 473-483
-
-
Seguchi, K.1
Kataoka, H.2
Uchino, H.3
Nabeshima, K.4
Koono, M.5
-
327
-
-
0028170818
-
Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease
-
Selkoe, D. J.: Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease. Annu. Rev. Cell Biol. 10: 373-403, 1994.
-
(1994)
Annu. Rev. Cell Biol.
, vol.10
, pp. 373-403
-
-
Selkoe, D.J.1
-
328
-
-
0022654027
-
Isolation of low-molecular-weight proteins from amyloid plaque fibers in Alzheimer's disease
-
Selkoe, D. J., Abraham, C. R., Podlisny, M. B. and Duffy, L. K.: Isolation of low-molecular-weight proteins from amyloid plaque fibers in Alzheimer's disease. J. Neurochem. 46(6): 1820- 1834, 1986.
-
(1986)
J. Neurochem.
, vol.46
, Issue.6
, pp. 1820-1834
-
-
Selkoe, D.J.1
Abraham, C.R.2
Podlisny, M.B.3
Duffy, L.K.4
-
329
-
-
0029933153
-
The role of APP processing and trafficking pathways in the formation of amyloid beta-protein
-
Selkoe, D. J., Yamazaki, T., Citron, M., Podlisny, M. B., Koo, E. H., Teplow, D. B. and Haass, C.: The role of APP processing and trafficking pathways in the formation of amyloid beta-protein. Ann. N. Y. Acad. Sci. 777: 57-64, 1996.
-
(1996)
Ann. N. Y. Acad. Sci.
, vol.777
, pp. 57-64
-
-
Selkoe, D.J.1
Yamazaki, T.2
Citron, M.3
Podlisny, M.B.4
Koo, E.H.5
Teplow, D.B.6
Haass, C.7
-
330
-
-
0002601147
-
Biochemistry of Alzheimer's disease and prion diseases
-
Sixth Edition, G. J. Siegel, B. W. Agranoff, R. W. Albers, S. K. Fisher, and M. D. Uhler, Eds., Lippincott-Raven, Philadelphia
-
Selkoe, D. J. and Lansbury, P. J. Jr.: Biochemistry of Alzheimer's disease and prion diseases. In: "Basic Neurochemistry, " Sixth Edition, G. J. Siegel, B. W. Agranoff, R. W. Albers, S. K. Fisher, and M. D. Uhler, Eds., pp. 950-968, Lippincott-Raven, Philadelphia, 1999.
-
(1999)
Basic Neurochemistry
, pp. 950-968
-
-
Selkoe, D.J.1
Lansbury, P.J.2
-
331
-
-
0031052339
-
Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5
-
Sengupta, A., Wu, Q., Grundke-Iqbal, I., Iqbal, K. and Singh, T. J.: Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5. Mol. Cell Biochem. 167(1-2): 99-105, 1997.
-
(1997)
Mol. Cell Biochem.
, vol.167
, Issue.1-2
, pp. 99-105
-
-
Sengupta, A.1
Wu, Q.2
Grundke-Iqbal, I.3
Iqbal, K.4
Singh, T.J.5
-
332
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
-
Seubert, P., Vigo-Pelfrey, C., Esch, F., Lee, M., Dovey, H., Davis, D., Sinha, S., Schlossmacher, M., Whaley, J., Swindlehurst, C., et al.: Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature 359(6393): 325-327, 1992.
-
(1992)
Nature
, vol.359
, Issue.6393
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
Sinha, S.7
Schlossmacher, M.8
Whaley, J.9
Swindlehurst, C.10
-
333
-
-
0029797410
-
The significance of the activity of CSF cholinesterases in dementias
-
Shen, Z.-X.: The significance of the activity of CSF cholinesterases in dementias. Med. Hypotheses 47: 363-376, 1996.
-
(1996)
Med. Hypotheses
, vol.47
, pp. 363-376
-
-
Shen, Z.-X.1
-
334
-
-
0842320909
-
The betaamyloid- related proeteins presenilins 1 and BACE1 are axonally transported to nerve terminals in the brain
-
Sheng, J. G., Price, D. L. and Koliatsos, V. E.: The betaamyloid- related proeteins presenilins 1 and BACE1 are axonally transported to nerve terminals in the brain. Exp. Neurol. 184: 1053-1057, 2003.
-
(2003)
Exp. Neurol.
, vol.184
, pp. 1053-1057
-
-
Sheng, J.G.1
Price, D.L.2
Koliatsos, V.E.3
-
335
-
-
0033813571
-
Neurotrophic factors in Alzheimer's and Parkinson's disease brain
-
Siegel, G. J. and Chauhan, N. B.: Neurotrophic factors in Alzheimer's and Parkinson's disease brain. Brain Res. Brain Res. Rev. 33(2-3): 199-227, 2000.
-
(2000)
Brain Res. Brain Res. Rev.
, vol.33
, Issue.2-3
, pp. 199-227
-
-
Siegel, G.J.1
Chauhan, N.B.2
-
336
-
-
0037339735
-
Localization of presenilinnicastrin complexes and gamma-secretase activity to the trans-Golginetwork
-
Siman, R. and Velji, J.: Localization of presenilinnicastrin complexes and gamma-secretase activity to the trans-Golginetwork. J. Neurochem. 84(5): 1143-1153, 2003.
-
(2003)
J. Neurochem.
, vol.84
, Issue.5
, pp. 1143-1153
-
-
Siman, R.1
Velji, J.2
-
337
-
-
0001719387
-
Histologische Sytudien über die senile Demenz
-
Simchowicz, T.: Histologische Sytudien über die senile Demenz. Nissl-Alzheimer Arbeiten 4: 267-444, 1911.
-
(1911)
Nissl-Alzheimer Arbeiten
, vol.4
, pp. 267-444
-
-
Simchowicz, T.1
-
338
-
-
0032568552
-
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons
-
Simons, M., Keller, P., De Strooper, B., Beyreuther, K., Dotti, C. G. and Simons, K.: Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc. Natl. Acad. Sci. U.S.A. 95(11): 6460-6464, 1998.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, Issue.11
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
339
-
-
0035949755
-
Cholesterol and Alzheimer's disease: Is there a link?
-
Simons, M., Keller, P., Dichgans, J. and Schulz, J. B.: Cholesterol and Alzheimer's disease: Is there a link? Neurology 57(6): 1089-1093, 2001.
-
(2001)
Neurology
, vol.57
, Issue.6
, pp. 1089-1093
-
-
Simons, M.1
Keller, P.2
Dichgans, J.3
Schulz, J.B.4
-
340
-
-
0026721943
-
Beta-amyloid precursor protein cleavage by a membrane-bound protease
-
Sisodia, S. S.: Beta-amyloid precursor protein cleavage by a membrane-bound protease. Proc. Natl. Acad. Sci. U.S.A. 89(13): 6075-6079, 1992.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, Issue.13
, pp. 6075-6079
-
-
Sisodia, S.S.1
-
341
-
-
0033518251
-
Purification and cloning of amyloid precursor protein beat-secretase from human brain
-
Sinha, S., Anderson, J. P., Barbour, R., Basi, G. S., Caccavello, R., Davis, D., Doan, M., Dovey, H. F., Frigon, N., Hong, J., Jacobson-Croak, K., Jewett, N., Keim, P., Knops, J., Lieberburg, I., Power, M., Tan, H., Tatsuno, G., Tung, J., Schenk, D., Seubert, P., Suomensaari, S. M., Wang, S., Walker, D., Zhao, J., McConlogue, L. and John, V.: Purification and cloning of amyloid precursor protein beat-secretase from human brain. Nature 402: 537-540, 1999.
-
(1999)
Nature
, vol.402
, pp. 537-540
-
-
Sinha, S.1
Anderson, J.P.2
Barbour, R.3
Basi, G.S.4
Caccavello, R.5
Davis, D.6
Doan, M.7
Dovey, H.F.8
Frigon, N.9
Hong, J.10
Jacobson-Croak, K.11
Jewett, N.12
Keim, P.13
Knops, J.14
Lieberburg, I.15
Power, M.16
Tan, H.17
Tatsuno, G.18
Tung, J.19
Schenk, D.20
Seubert, P.21
Suomensaari, S.M.22
Wang, S.23
Walker, D.24
Zhao, J.25
McConlogue, L.26
John, V.27
more..
-
342
-
-
0027212769
-
Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system
-
Sisodia, S. S., Koo, E. H., Hoffman, P. N., Perry, G. and Price, D. L.: Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system. J. Neurosci. 13(7): 3136-3142, 1993.
-
(1993)
J. Neurosci.
, vol.13
, Issue.7
, pp. 3136-3142
-
-
Sisodia, S.S.1
Koo, E.H.2
Hoffman, P.N.3
Perry, G.4
Price, D.L.5
-
343
-
-
0034723418
-
Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-Golginetwork
-
Skovronsky, D. M., Moore, D. B., Milla, M. E., Doms, R. W. and Lee, V. M.: Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-Golginetwork. J. Biol. Chem. 275(4): 2568- 2575, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.4
, pp. 2568-2575
-
-
Skovronsky, D.M.1
Moore, D.B.2
Milla, M.E.3
Doms, R.W.4
Lee, V.M.5
-
344
-
-
18244365872
-
Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: The chickens or the eggs?
-
Smith, M. A., Drew, K. L., Nunomura, A., Takeda, A., Hirai, K., Zhu, X., Atwood, C. S., Raina, A. K., Rottkamp, C. A., Sayre, L. M., Friedland, R. P. and Perry, G.: Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: The chickens or the eggs? Neurochem. Int. 40(6): 527-531, 2002.
-
(2002)
Neurochem. Int.
, vol.40
, Issue.6
, pp. 527-531
-
-
Smith, M.A.1
Drew, K.L.2
Nunomura, A.3
Takeda, A.4
Hirai, K.5
Zhu, X.6
Atwood, C.S.7
Raina, A.K.8
Rottkamp, C.A.9
Sayre, L.M.10
Friedland, R.P.11
Perry, G.12
-
345
-
-
0025365401
-
Platelet coagulation factor XIa-inhibitor, a form of Alzheimer amyloid precursor protein
-
Smith, R. P., Higuchi, D. A. and Broze, G. J. Jr.: Platelet coagulation factor XIa-inhibitor, a form of Alzheimer amyloid precursor protein. Science 248(4959): 1126- 1128, 1990.
-
(1990)
Science
, vol.248
, Issue.4959
, pp. 1126-1128
-
-
Smith, R.P.1
Higuchi, D.A.2
Broze, G.J.3
-
346
-
-
0038267245
-
CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling
-
Song, D. H., Dominguez, I., Mizuno, J., Kaut, M., Mohr, S. C. and Seldin, D. C.: CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling. J. Biol. Chem. 278(26): 24018- 24025, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.26
, pp. 24018-24025
-
-
Song, D.H.1
Dominguez, I.2
Mizuno, J.3
Kaut, M.4
Mohr, S.C.5
Seldin, D.C.6
-
347
-
-
16844379776
-
Interferon gamma induces neurite outgrowth by upregulation of p35 neuron-specific cyclin-dependent kinase 5 activator via activation of ERK1/2 pathway
-
Song, J. H., Wang, C. X., Song, D. K., Wang, P., et al.: Interferon gamma induces neurite outgrowth by upregulation of p35 neuron-specific cyclin-dependent kinase 5 activator via activation of ERK1/2 pathway. J Biol. Chem. 280: 12896-12901, 2005.
-
(2005)
J Biol. Chem.
, vol.280
, pp. 12896-12901
-
-
Song, J.H.1
Wang, C.X.2
Song, D.K.3
Wang, P.4
-
348
-
-
0035911156
-
Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing
-
Soriano, S., Kang, D. E., Fu, M., Pestell, R., Chevallier, N., Zheng, H. and Koo, E. H.: Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing. J. Cell Biol. 152(4): 785-794, 2001.
-
(2001)
J. Cell Biol.
, vol.152
, Issue.4
, pp. 785-794
-
-
Soriano, S.1
Kang, D.E.2
Fu, M.3
Pestell, R.4
Chevallier, N.5
Zheng, H.6
Koo, E.H.7
-
349
-
-
0036326442
-
ELISA analysis of beta-secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways
-
Steinhilb, M. L., Turner, R. S. and Gaut, J. R.: ELISA analysis of beta-secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways. J. Neurochem. 80(6): 1019-1028, 2002.
-
(2002)
J. Neurochem.
, vol.80
, Issue.6
, pp. 1019-1028
-
-
Steinhilb, M.L.1
Turner, R.S.2
Gaut, J.R.3
-
350
-
-
0038176528
-
In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis
-
Stine, W. B. Jr., Dahlgren, K. N., Krafft, G. A. and LaDu, M. J.: In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis. J. Biol. Chem. 278(13): 11612-11622, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.13
, pp. 11612-11622
-
-
Stine, W.B.1
Dahlgren, K.N.2
Krafft, G.A.3
LaDu, M.J.4
-
351
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter, W. J., Saunders, A. M., Schmechel, D., Pericak-Vance, M., Enghild, J., Salvesen, G. S. and Roses, A. D.: Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 90(5): 1977-1981, 1993.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, Issue.5
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
352
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat, C., Abramowski, D., Duke, M., Wiederhold, K. H., Mistl, C., Rothacher, S., Ledermann, B., Burki, K., Frey, P., Paganetti, P. A., Waridel, C., Calhoun, M. E., Jucker, M., Probst, A., Staufenbiel, M. and Sommer, B.: Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc. Natl. Acad. Sci. U.S.A. 94(24): 13287-13292, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.24
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Burki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
353
-
-
0033535989
-
Acute cholesterol depletion inhibits clathrin-coated pit budding
-
Subtil, A., Gaidarov, I., Kobylarz, K., Lampson, M. A., Keen, J. H. and McGraw, T. E.: Acute cholesterol depletion inhibits clathrin-coated pit budding. Proc. Natl. Acad. Sci. U.S.A. 96(12): 6775-6780, 1999.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, Issue.12
, pp. 6775-6780
-
-
Subtil, A.1
Gaidarov, I.2
Kobylarz, K.3
Lampson, M.A.4
Keen, J.H.5
McGraw, T.E.6
-
354
-
-
0036736218
-
Amyloid precursor protein, presenilins, and alpha-synuclein: Molecular pathogenesis and pharmacological applications in Alzheimer's disease
-
Suh, Y. H. and Checler, F.: Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease. Pharmacol. Rev. 54(3): 469- 525, 2002.
-
(2002)
Pharmacol. Rev.
, vol.54
, Issue.3
, pp. 469-525
-
-
Suh, Y.H.1
Checler, F.2
-
355
-
-
0037404666
-
Abeta42 generation is toxic to endothelial cells and inhibits eNOS function through an Akt/GSK-3beta signaling-dependent mechanism
-
Suhara, T., Magrane, J., Rosen, K., Christensen, R., Kim, H. S., Zheng, B., McPhie, D. L., Walsh, K. and Querfurth, H.: Abeta42 generation is toxic to endothelial cells and inhibits eNOS function through an Akt/GSK-3beta signaling-dependent mechanism. Neurobiol. Aging 24(3): 437-451, 2003.
-
(2003)
Neurobiol. Aging
, vol.24
, Issue.3
, pp. 437-451
-
-
Suhara, T.1
Magrane, J.2
Rosen, K.3
Christensen, R.4
Kim, H.S.5
Zheng, B.6
McPhie, D.L.7
Walsh, K.8
Querfurth, H.9
-
356
-
-
4644262635
-
Cerebral hypoperfusion and amyloid-induced synergistic impairment of hippocampal CA1 synaptic efficacy and spatial memory in young adult rats
-
Sun, M. K. and Alkon, D. L.: Cerebral hypoperfusion and amyloid-induced synergistic impairment of hippocampal CA1 synaptic efficacy and spatial memory in young adult rats. J. Alzheimers Dis. 6: 355-366, 2004.
-
(2004)
J. Alzheimers Dis.
, vol.6
, pp. 355-366
-
-
Sun, M.K.1
Alkon, D.L.2
-
357
-
-
0037087220
-
Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
-
Sun, X., Sato, S., Murayama, O., Murayama, M., Park, J. M., Yamaguchi, H. and Takashima, A.: Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci. Lett. 321(1-2): 61-64, 2002.
-
(2002)
Neurosci. Lett.
, vol.321
, Issue.1-2
, pp. 61-64
-
-
Sun, X.1
Sato, S.2
Murayama, O.3
Murayama, M.4
Park, J.M.5
Yamaguchi, H.6
Takashima, A.7
-
358
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
Suzuki, N., Cheung, T. T., Cai, X. D., Odaka, A., Otvos, L. Jr., Eckman, C., Golde, T. E. and Younkin, S. G.: An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 264(5163): 1336- 1340, 1994.
-
(1994)
Science
, vol.264
, Issue.5163
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos, L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
359
-
-
0001658193
-
Cholinesterase inhibitors do more than inhibit cholinesterase
-
E. Giacobini, Ed., Martin Dunitz, London
-
Svensson, A.-L. and Giacobini, E.: Cholinesterase inhibitors do more than inhibit cholinesterase. In: "Cholinesterases and Cholinesterase Inhibitors, " E. Giacobini, Ed., pp. 227-235, Martin Dunitz, London, 2000.
-
(2000)
Cholinesterases and Cholinesterase Inhibitors
, pp. 227-235
-
-
Svensson, A.-L.1
Giacobini, E.2
-
360
-
-
0035992639
-
Induction of transcriptional activity of the cyclic adenosine monophosphate response element binding protein by parathyroid hormone and epidermal growth factor in osteoblastic cells
-
Erratum in: J. Bone Miner. Res. 17(10): 1917, 2002
-
Swarthout, J. T., Tyson, D. R., Jefcoat, S. C. Jr., Partridge, N. C. and Efcoat, S. C. Jr.: Induction of transcriptional activity of the cyclic adenosine monophosphate response element binding protein by parathyroid hormone and epidermal growth factor in osteoblastic cells. J. Bone Miner. Res. 17(8): 1401- 1407, 2002. Erratum in: J. Bone Miner. Res. 17(10): 1917, 2002.
-
(2002)
J. Bone Miner. Res.
, vol.17
, Issue.8
, pp. 1401-1407
-
-
Swarthout, J.T.1
Tyson, D.R.2
Jefcoat, S.C.3
Partridge, N.C.4
Efcoat, S.C.5
-
361
-
-
0028892186
-
Amyloid beta peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I/glycogen synthase kinase-3 beta in rat hippocampal neurons
-
Takashima, A., Yamaguchi, H., Noguchi, K., Michel, G., Ishiguro, K., Sato, K., Hoshino, T., Hoshi, M. and Imahori, K.: Amyloid beta peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I/glycogen synthase kinase-3 beta in rat hippocampal neurons. Neurosci. Lett. 198(2): 83-86, 1995.
-
(1995)
Neurosci. Lett.
, vol.198
, Issue.2
, pp. 83-86
-
-
Takashima, A.1
Yamaguchi, H.2
Noguchi, K.3
Michel, G.4
Ishiguro, K.5
Sato, K.6
Hoshino, T.7
Hoshi, M.8
Imahori, K.9
-
362
-
-
0030044463
-
Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta
-
Takashima, A., Noguchi, K., Michel, G., Mercken, M., Hoshi, M., Ishiguro, K. and Imahori, K.: Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta. Neurosci. Lett. 203(1): 33-36, 1996.
-
(1996)
Neurosci. Lett.
, vol.203
, Issue.1
, pp. 33-36
-
-
Takashima, A.1
Noguchi, K.2
Michel, G.3
Mercken, M.4
Hoshi, M.5
Ishiguro, K.6
Imahori, K.7
-
363
-
-
0031695652
-
Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons
-
Takashima, A., Honda, T., Yasutake, K., Michel, G., Murayama, O., Murayama, M., Ishiguro, K. and Yamaguchi, H.: Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons. Neurosci Res. 31(4): 317- 323, 1998a.
-
(1998)
Neurosci Res.
, vol.31
, Issue.4
, pp. 317-323
-
-
Takashima, A.1
Honda, T.2
Yasutake, K.3
Michel, G.4
Murayama, O.5
Murayama, M.6
Ishiguro, K.7
Yamaguchi, H.8
-
364
-
-
13144265717
-
Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau
-
Takashima, A., Murayama, M., Murayama, O., Kohno, T., Honda, T., Yasutake, K., Nihonmatsu, N., Mercken, M., Yamaguchi, H., Sugihara, S. and Wolozin, B.: Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau. Proc. Natl. Acad. Sci. U.S.A. 95(16): 9637-9641, 1998b.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, Issue.16
, pp. 9637-9641
-
-
Takashima, A.1
Murayama, M.2
Murayama, O.3
Kohno, T.4
Honda, T.5
Yasutake, K.6
Nihonmatsu, N.7
Mercken, M.8
Yamaguchi, H.9
Sugihara, S.10
Wolozin, B.11
-
365
-
-
0034678357
-
The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression
-
Takemaru, K. I. and Moon, R.T.: The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression. J. Cell Biol. 149(2): 249-254, 2000.
-
(2000)
J. Cell Biol.
, vol.149
, Issue.2
, pp. 249-254
-
-
Takemaru, K.I.1
Moon, R.T.2
-
366
-
-
0037969981
-
Atrophy of the substantia innominata on magnetic resonance imaging predicts response to donepezil treatment in Alzheimer's disease patients
-
Tanaka, Y., Hanya, H., Sakurai, H., Takasaki, M. and Abe, K.: Atrophy of the substantia innominata on magnetic resonance imaging predicts response to donepezil treatment in Alzheimer's disease patients. Dement. Geriatr. Cogn. Disord. 16: 119-1125, 2003.
-
(2003)
Dement. Geriatr. Cogn. Disord.
, vol.16
, pp. 119-1125
-
-
Tanaka, Y.1
Hanya, H.2
Sakurai, H.3
Takasaki, M.4
Abe, K.5
-
367
-
-
0036432244
-
The presenilins
-
reviews 3014
-
Tandon, A. and Fraser, P.: The presenilins. Genome Biol. 3(11): Reviews 3014, 2002.
-
(2002)
Genome Biol.
, vol.3
, Issue.11
-
-
Tandon, A.1
Fraser, P.2
-
368
-
-
0036138044
-
Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau
-
Tanemura, K., Murayama, M., Akagi, T., Hashikawa, T., Tominaga, T., Ichikawa, M., Yamaguchi, H. and Takashima, A.: Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau. J. Neurosci. 22(1): 133-141, 2002.
-
(2002)
J. Neurosci.
, vol.22
, Issue.1
, pp. 133-141
-
-
Tanemura, K.1
Murayama, M.2
Akagi, T.3
Hashikawa, T.4
Tominaga, T.5
Ichikawa, M.6
Yamaguchi, H.7
Takashima, A.8
-
369
-
-
0023635239
-
The amyloid beta protein gene is not duplicated in brains from patients with Alzheimer's disease
-
Tanzi, R. E., Bird, E. D., Latt, S. A. and Neve, R. L.: The amyloid beta protein gene is not duplicated in brains from patients with Alzheimer's disease. Science 238(4827): 666-669, 1987.
-
(1987)
Science
, vol.238
, Issue.4827
, pp. 666-669
-
-
Tanzi, R.E.1
Bird, E.D.2
Latt, S.A.3
Neve, R.L.4
-
370
-
-
0023850791
-
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease
-
Tanzi, R. E., McClatchey, A. I., Lamperti, E. D., Villa- Komaroff, L., Gusella, J. F. and Neve, R. L.: Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature 331(6156): 528-530, 1988.
-
(1988)
Nature
, vol.331
, Issue.6156
, pp. 528-530
-
-
Tanzi, R.E.1
McClatchey, A.I.2
Lamperti, E.D.3
Villa- Komaroff, L.4
Gusella, J.F.5
Neve, R.L.6
-
371
-
-
0037108953
-
Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau
-
Tatebayashi, Y., Miyasaka, T., Chui, D. H., Akagi, T., Mishima, K., Iwasaki, K., Fujiwara, M., Tanemura, K., Murayama, M., Ishiguro, K., Planel, E., Sato, S., Hashikawa, T. and Takashima, A.: Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. Proc. Natl. Acad. Sci. U.S.A. 99(21): 13896-13901, 2002.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, Issue.21
, pp. 13896-13901
-
-
Tatebayashi, Y.1
Miyasaka, T.2
Chui, D.H.3
Akagi, T.4
Mishima, K.5
Iwasaki, K.6
Fujiwara, M.7
Tanemura, K.8
Murayama, M.9
Ishiguro, K.10
Planel, E.11
Sato, S.12
Hashikawa, T.13
Takashima, A.14
-
372
-
-
13344293701
-
Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome
-
Teller, J. K., Russo, C., DeBusk, L. M., Angelini, G., Zaccheo, D., Dagna-Bricarelli, F., Scartezzini, P., Bertolini, S., Mann, D. M., Tabaton, M. and Gambetti, P.: Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome. Nat. Med. 2(1): 93-95, 1996.
-
(1996)
Nat. Med., 93-95
, vol.2
, Issue.1
-
-
Teller, J.K.1
Russo, C.2
DeBusk, L.M.3
Angelini, G.4
Zaccheo, D.5
Dagna-Bricarelli, F.6
Scartezzini, P.7
Bertolini, S.8
Mann, D.M.9
Tabaton, M.10
Gambetti, P.11
-
373
-
-
0002080057
-
The neuropathology of Alzheimer disease and the structural basis of its cognitive alterations
-
Second Edition, R. D. Terry, R. Katzman, K. L. Bick, and S. S. Sisodia, Eds., Lippincott, Williams and Wilkins, Philadelphia
-
Terry, R. D., Masliah, E. and Hansen, L. A.: The neuropathology of Alzheimer disease and the structural basis of its cognitive alterations. In: "Alzheimer Disease, " Second Edition, R. D. Terry, R. Katzman, K. L. Bick, and S. S. Sisodia, Eds., pp. 187-206, Lippincott, Williams and Wilkins, Philadelphia, 1999.
-
(1999)
Alzheimer Disease
, pp. 187-206
-
-
Terry, R.D.1
Masliah, E.2
Hansen, L.A.3
-
374
-
-
0020633185
-
Oral physostigmine and lecithin improve memory in Alzheimer's disease
-
Thal, L. J., Fuld, P. A., Masur, D. M. and Sharpless, N. S.: Oral physostigmine and lecithin improve memory in Alzheimer's disease. Ann. Neurol. 13: 491-496, 1983.
-
(1983)
Ann. Neurol.
, vol.13
, pp. 491-496
-
-
Thal, L.J.1
Fuld, P.A.2
Masur, D.M.3
Sharpless, N.S.4
-
375
-
-
0344738681
-
Idebenone treatment fails to slow cognitive decline in Alzheimer's disease
-
Thal, L. J., Grundman, B., Berg, J., Ernstrom, K., Margolin, E., Pfeiffer, E., Weiner, M. F., Zamrini, E. and Thomas, R. G.: Idebenone treatment fails to slow cognitive decline in Alzheimer's disease. Neurology 61: 1498-1502, 2003.
-
(2003)
Neurology
, vol.61
, pp. 1498-1502
-
-
Thal, L.J.1
Grundman, B.2
Berg, J.3
Ernstrom, K.4
Margolin, E.5
Pfeiffer, E.6
Weiner, M.F.7
Zamrini, E.8
Thomas, R.G.9
-
376
-
-
0141763651
-
Cholinergic modulation of learning and memory in the human brain as detected with functional neuroimaging
-
Thiel, C. M.: Cholinergic modulation of learning and memory in the human brain as detected with functional neuroimaging. Neurobiol. Learn. Mem. 80: 233-244, 2003.
-
(2003)
Neurobiol. Learn. Mem.
, vol.80
, pp. 233-244
-
-
Thiel, C.M.1
-
377
-
-
0020383628
-
Plaques, tangles and Alzheimer's disease
-
Tomlison, B. E.: Plaques, tangles and Alzheimer's disease. Psychol. Med. 12: 449-459, 1982.
-
(1982)
Psychol. Med.
, vol.12
, pp. 449-459
-
-
Tomlison, B.E.1
-
378
-
-
0036321305
-
Investigating emergent symptomatology as an outcome measure in a behavioral study of Alzheimer's disease
-
Tractenberg, R. E., Gamst, A., Thomas, R. G., Patterson, M., Schneider, L. S. and Thal, L.J.: Investigating emergent symptomatology as an outcome measure in a behavioral study of Alzheimer's disease. J. Neuropsychiatry Clin. Neurosci. 14: 303-310, 2002.
-
(2002)
J. Neuropsychiatry Clin. Neurosci.
, vol.14
, pp. 303-310
-
-
Tractenberg, R.E.1
Gamst, A.2
Thomas, R.G.3
Patterson, M.4
Schneider, L.S.5
Thal, L.J.6
-
379
-
-
0035879074
-
Death in the balance: Alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation
-
Erratum in: J. Neurosci. 21(16): 1b, 2001
-
Troy, C. M., Rabacchi, S. A., Hohl, J. B., Angelastro, J. M., Greene, L. A. and Shelanski, M. L.: Death in the balance: Alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation. J. Neurosci. 21(14): 5007-5016, 2001. Erratum in: J. Neurosci. 21(16): 1b, 2001.
-
(2001)
J. Neurosci.
, vol.21
, Issue.14
, pp. 5007-5016
-
-
Troy, C.M.1
Rabacchi, S.A.2
Hohl, J.B.3
Angelastro, J.M.4
Greene, L.A.5
Shelanski, M.L.6
-
380
-
-
1542344008
-
Effects of acute acetylcholinesterase inhibition on the cerebral cholinergic neuronal system and cognitive function: Functional imaging of the conscious monkey brain using animal PET in combination with microdialysis
-
Tsukada, H., Nishiyama, S., Fukumoto, D., Ohba, H., Sato, K. and Kakiuchi, T.: Effects of acute acetylcholinesterase inhibition on the cerebral cholinergic neuronal system and cognitive function: functional imaging of the conscious monkey brain using animal PET in combination with microdialysis. Synapse 52: 1-10, 2004.
-
(2004)
Synapse
, vol.52
, pp. 1-10
-
-
Tsukada, H.1
Nishiyama, S.2
Fukumoto, D.3
Ohba, H.4
Sato, K.5
Kakiuchi, T.6
-
381
-
-
21044458854
-
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease
-
Tuszynski, M. H., Thal, L., Pay, M., Salmon, D. P., U, H. S., Bakay, R., Patel, P., Blesch, A., Vahlsing, H. L., Ho, G., Tong, G., Potkin, S. G., Fallon, J., Hansen, L., Mufson, E. J., Kordower, J. H., Gall, C. and Conner, J.: A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat. Med. 11: 551-555, 2005 .
-
(2005)
Nat. Med.
, vol.11
, pp. 551-555
-
-
Tuszynski, M.H.1
Thal, L.2
Pay, M.3
Salmon, D.P.4
-
382
-
-
0036157857
-
PTH induction of transcriptional activity of the cAMP response elementbinding protein requires the serine 129 site and glycogen synthase kinase-3 activity, but not casein kinase II sites
-
Tyson, D. R., Swarthout, J. T., Jefcoat, S. C. and Partridge, N. C.: PTH induction of transcriptional activity of the cAMP response elementbinding protein requires the serine 129 site and glycogen synthase kinase-3 activity, but not casein kinase II sites. Endocrinology 143(2): 674-682, 2002.
-
(2002)
Endocrinology
, vol.143
, Issue.2
, pp. 674-682
-
-
Tyson, D.R.1
Swarthout, J.T.2
Jefcoat, S.C.3
Partridge, N.C.4
-
383
-
-
0032871188
-
Lipoprotein receptor-related protein in brain and in cultured neurons of mice deficient in receptor-associated protein and transgenic for apolipoprotein E4 or amyloid precursor protein
-
Umans, L., Serneels, L., Lorent, K., Dewachter, I., Tesseur, I., Moechars, D. and Van Leuven, F.: Lipoprotein receptor-related protein in brain and in cultured neurons of mice deficient in receptor-associated protein and transgenic for apolipoprotein E4 or amyloid precursor protein. Neuroscience 94(1): 315-321, 1999.
-
(1999)
Neuroscience
, vol.94
, Issue.1
, pp. 315-321
-
-
Umans, L.1
Serneels, L.2
Lorent, K.3
Dewachter, I.4
Tesseur, I.5
Moechars, D.6
Van Leuven, F.7
-
384
-
-
0030908590
-
Phosphorylation of tau by glycogen synthase kinase 3beta affects the ability of tau to promote microtubule self-assembly
-
Utton, M. A., Vandecandelaere, A., Wagner, U., Reynolds, C. H., Gibb, G. M., Miller, C. C., Bayley, P. M., Anderton, B. H.: Phosphorylation of tau by glycogen synthase kinase 3beta affects the ability of tau to promote microtubule self-assembly. Biochem. J. 323, Pt. 3: 741-747, 1997.
-
(1997)
Biochem. J.
, vol.323
, pp. 741-747
-
-
Utton, M.A.1
Vandecandelaere, A.2
Wagner, U.3
Reynolds, C.H.4
Gibb, G.M.5
Miller, C.C.6
Bayley, P.M.7
Anderton, B.H.8
-
385
-
-
0034218323
-
Evidence that the beta-catenin nuclear translocation assay allows for measuring presenilin 1 dysfunction
-
Van Gassen, G., De Jonghe, C., Nishimura, M., Yu, G., Kuhn, S., St. George-Hyslop, P. and Van Broeckhoven, C.: Evidence that the beta-catenin nuclear translocation assay allows for measuring presenilin 1 dysfunction. Mol. Med. 6(7): 570-580, 2000.
-
(2000)
Mol. Med.
, vol.6
, Issue.7
, pp. 570-580
-
-
Van Gassen, G.1
De Jonghe, C.2
Nishimura, M.3
Yu, G.4
Kuhn, S.5
George-Hyslop, P.6
Van Broeckhoven, C.7
-
386
-
-
0024463491
-
Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor
-
Van Nostrand, W. E., Wagner, S. L., Suzuki, M., Choi, B. H., Farrow, J. S., Geddes, J. W., Cotman, C. W. and Cunningham, D. D.: Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor. Nature 341(6242): 546-549, 1989.
-
(1989)
Nature
, vol.341
, Issue.6242
, pp. 546-549
-
-
Van Nostrand, W.E.1
Wagner, S.L.2
Suzuki, M.3
Choi, B.H.4
Farrow, J.S.5
Geddes, J.W.6
Cotman, C.W.7
Cunningham, D.D.8
-
387
-
-
0025357613
-
Immunopurification and protease inhibitory properties of protease nexin-2/amyloid beta-protein precursor
-
Van Nostrand, W. E., Wagner, S. L., Farrow, J. S. and Cunningham, D. D.: Immunopurification and protease inhibitory properties of protease nexin-2/amyloid beta-protein precursor. J. Biol. Chem. 265(17): 9591- 9594, 1990.
-
(1990)
J. Biol. Chem.
, vol.265
, Issue.17
, pp. 9591-9594
-
-
Van Nostrand, W.E.1
Wagner, S.L.2
Farrow, J.S.3
Cunningham, D.D.4
-
388
-
-
0028568061
-
Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid beta-protein precursor-like protein-2
-
Van Nostrand, W. E., Schmaier, A. H., Neiditch, B. R., Siegel, R. S., Raschke, W. C., Sisodia, S. S. and Wagner, S. L.: Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid beta-protein precursor-like protein-2. Biochim. Biophys. Acta 1209(2): 165- 170, 1994.
-
(1994)
Biochim. Biophys. Acta
, vol.1209
, Issue.2
, pp. 165-170
-
-
Van Nostrand, W.E.1
Schmaier, A.H.2
Neiditch, B.R.3
Siegel, R.S.4
Raschke, W.C.5
Sisodia, S.S.6
Wagner, S.L.7
-
389
-
-
0035980088
-
Pathogenic effects of D23N Iowa mutant amyloid beta-protein
-
Van Nostrand, W. E., Melchor, J. P., Cho, H. S., Greenberg, S. M. and Rebeck, G. W.: Pathogenic effects of D23N Iowa mutant amyloid beta-protein. J. Biol. Chem. 276(35): 32860-32866, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.35
, pp. 32860-32866
-
-
Van Nostrand, W.E.1
Melchor, J.P.2
Cho, H.S.3
Greenberg, S.M.4
Rebeck, G.W.5
-
390
-
-
0033595706
-
Betasecretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., Teplow, D. B., Ross, S., Amarante, P., Loeloff, R., Luo, Y., Fisher, S., Fuller, J., Edenson, S., Lile, J., Jarosinski, M. A., Biere, A. L., Curran, E., Burgess, T., Louis, J. C., Collins, F., Treanor, J., Rogers, G. and Citron, M.: Betasecretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286: 735-741, 1999.
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
391
-
-
0002152567
-
-
Second Edition, R. D. Terry, R. Katzman, K. L. Bick, and S. S. Sisodia, Eds., Lippincott, Williams and Wilkins, Philadelphia
-
Vogelsberg-Ragaglia, V., Trojanowski, J. Q., Lee, V. M.- Y. In: "Alzheimer Disease, " Second Edition, R. D. Terry, R. Katzman, K. L. Bick, and S. S. Sisodia, Eds., pp. 359-372, Lippincott, Williams and Wilkins, Philadelphia, 1999.
-
(1999)
Alzheimer Disease
, pp. 359-372
-
-
Vogelsberg-Ragaglia, V.1
Trojanowski, J.Q.2
Lee V.M.-., Y.3
-
392
-
-
0031470093
-
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice. Neurobiol
-
Von Koch, C. S., Zheng, H., Chen, H., Trumbauer, M., Thinakaran, G., van der Ploeg, L. H., Price, D. L. and Sisodia, S. S.: Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice. Neurobiol. Aging 18(6): 661-669, 1997.
-
(1997)
Aging
, vol.18
, Issue.6
, pp. 661-669
-
-
Von Koch, C.S.1
Zheng, H.2
Chen, H.3
Trumbauer, M.4
Thinakaran, G.5
Van Der Ploeg, L.H.6
Price, D.L.7
Sisodia, S.S.8
-
393
-
-
0034720732
-
Fibrillar amyloid betaprotein binds protease nexin-2/amyloid beta-protein precursor: Stimulation of its inhibition of coagulation factor XIa
-
Wagner, M. R., Keane, D. M., Melchor, J. P., Auspaker, K. R., Van Nostrand, W. E.: Fibrillar amyloid betaprotein binds protease nexin-2/amyloid beta-protein precursor: Stimulation of its inhibition of coagulation factor XIa. Biochemistry 39(25): 7420-7427, 2000.
-
(2000)
Biochemistry
, vol.39
, Issue.25
, pp. 7420-7427
-
-
Wagner, M.R.1
Keane, D.M.2
Melchor, J.P.3
Auspaker, K.R.4
Van Nostrand, W.E.5
-
394
-
-
0029998294
-
Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation
-
Wagner, U., Utton, M., Gallo, J. M. and Miller, C. C.: Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation. J. Cell Sci. 109, Pt. 6: 1537-1543, 1996.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 1537-1543
-
-
Wagner, U.1
Utton, M.2
Gallo, J.M.3
Miller, C.C.4
-
395
-
-
0031567596
-
Overexpression of the mouse dishevelled-1 protein inhibits GSK- 3beta-mediated phosphorylation of tau in transfected mammalian cells
-
Wagner, U., Brownlees, J., Irving, N. G., Lucas, F. R., Salinas, P. C. and Miller, C. C.: Overexpression of the mouse dishevelled-1 protein inhibits GSK- 3beta-mediated phosphorylation of tau in transfected mammalian cells. FEBS Lett. 411(2-3): 369-372, 1997.
-
(1997)
FEBS Lett.
, vol.411
, Issue.2-3
, pp. 369-372
-
-
Wagner, U.1
Brownlees, J.2
Irving, N.G.3
Lucas, F.R.4
Salinas, P.C.5
Miller, C.C.6
-
396
-
-
0035823518
-
Cellular membrane composition defines A beta-lipid interactions
-
Waschuk, S. A., Elton, E. A., Darabie, A. A., Fraser, P. E. and McLaurin, J. A.: Cellular membrane composition defines A beta-lipid interactions. J. Biol. Chem. 276(36): 33561-33568, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.36
, pp. 33561-33568
-
-
Waschuk, S.A.1
Elton, E.A.2
Darabie, A.A.3
Fraser, P.E.4
McLaurin, J.A.5
-
397
-
-
0036085702
-
Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than do healthy elderly individuals
-
Weksler, M. E., Relkin, N., Turkenich, R., LaRusse, S., Zhou, L. and Szabo, P.: Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than do healthy elderly individuals. Exp. Gerontol. 37: 943-948, 2002.
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 943-948
-
-
Weksler, M.E.1
Relkin, N.2
Turkenich, R.3
LaRusse, S.4
Zhou, L.5
Szabo, P.6
-
398
-
-
0019410162
-
Alzheimer's disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
-
Whitehouse, P. J., Price, D. L., Clark, A. W. Jr., Coyle, J. T. and DeLong, M. R.: Alzheimer's disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann. Neurol. 10: 122-126, 1981.
-
(1981)
Ann. Neurol.
, vol.10
, pp. 122-126
-
-
Whitehouse, P.J.1
Price, D.L.2
Clark, A.W.3
Coyle, J.T.4
DeLong, M.R.5
-
399
-
-
0020072221
-
Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain
-
Whitehouse, P. J., Price, D. L., Struble, R. G., Clark, A. W., Coyle, J. T. and DeLong, M. R.: Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain. Science 215: 1237-1239, 1982.
-
(1982)
Science
, vol.215
, pp. 1237-1239
-
-
Whitehouse, P.J.1
Price, D.L.2
Struble, R.G.3
Clark, A.W.4
Coyle, J.T.5
DeLong, M.R.6
-
400
-
-
0022457840
-
Nicotinic acetylcholine binding sites in Alzheimer's disease
-
Whitehouse, P. J., Martino, A. M., Antuono, P. G., Lowenstein, P. R., Coyle, J. T., Price, D. L. and Kellar, K. J.: Nicotinic acetylcholine binding sites in Alzheimer's disease. Brain Res. 371: 146-151, 1986.
-
(1986)
Brain Res.
, vol.371
, pp. 146-151
-
-
Whitehouse, P.J.1
Martino, A.M.2
Antuono, P.G.3
Lowenstein, P.R.4
Coyle, J.T.5
Price, D.L.6
Kellar, K.J.7
-
401
-
-
0030952217
-
Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42
-
Wild-Bode, C., Yamazaki, T., Capell, A., Leimer, U., Steiner, H., Ihara, Y. and Haass, C.: Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42. J. Biol. Chem. 272(26): 16085-16088, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.26
, pp. 16085-16088
-
-
Wild-Bode, C.1
Yamazaki, T.2
Capell, A.3
Leimer, U.4
Steiner, H.5
Ihara, Y.6
Haass, C.7
-
402
-
-
0036727463
-
Presenilins are not required for A beta 42 production in the early secretory pathway
-
Wilson, C. A., Doms, R. W., Zheng, H. and Lee, V. M.: Presenilins are not required for A beta 42 production in the early secretory pathway. Nat. Neurosci. 5(9): 849-855, 2002.
-
(2002)
Nat. Neurosci.
, vol.5
, Issue.9
, pp. 849-855
-
-
Wilson, C.A.1
Doms, R.W.2
Zheng, H.3
Lee, V.M.4
-
403
-
-
9844257889
-
Clinical, pathological and biochemical aspects of Alzheimer's disease
-
A. Fisher, I. Hanin and C. Lachman, Eds., Plenum Press, New York
-
Wisniewski, H. M.: Clinical, pathological and biochemical aspects of Alzheimer's disease. In: "Alzheimer's and Parkinson's Diseases, " A. Fisher, I. Hanin and C. Lachman, Eds., pp. 25-36, Plenum Press, New York, 1987.
-
(1987)
Alzheimer's and Parkinson's Diseases
, pp. 25-36
-
-
Wisniewski, H.M.1
-
404
-
-
4143084775
-
Intramembrane proteolysis: Theme and variations
-
Wolfe, M. S. and Kopan, R.: Intramembrane proteolysis: Theme and variations. Science 305: 1119-1123, 2004.
-
(2004)
Science
, vol.305
, pp. 1119-1123
-
-
Wolfe, M.S.1
Kopan, R.2
-
405
-
-
0037150534
-
Biochemistry. Intramembrane proteases-mixing oil and water
-
Wolfe, M. S. and Selkoe, D. J.: Biochemistry. Intramembrane proteases-mixing oil and water. Science 296(5576): 2156-2157, 2002.
-
(2002)
Science
, vol.296
, Issue.5576
, pp. 2156-2157
-
-
Wolfe, M.S.1
Selkoe, D.J.2
-
406
-
-
0033535553
-
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
-
Wolfe, M. S., Xia, W., Ostaszewski, B. L., Diehl, T. S., Kimberly, W. T., Selkoe, D. J.: Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature 398(6727): 513-517, 1999.
-
(1999)
Nature
, vol.398
, Issue.6727
, pp. 513-517
-
-
Wolfe, M.S.1
Xia, W.2
Ostaszewski, B.L.3
Diehl, T.S.4
Kimberly, W.T.5
Selkoe, D.J.6
-
407
-
-
0023617654
-
Alzheimer-related neuronal protein A68: Specificity and distribution
-
Wolozin, B. and Davis, P.: Alzheimer-related neuronal protein A68: Specificity and distribution. Ann. Neurol. 202: 521-526, 1987.
-
(1987)
Ann. Neurol.
, vol.202
, pp. 521-526
-
-
Wolozin, B.1
Davis, P.2
-
408
-
-
0033772113
-
Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
-
Wolozin, B., Kellman, W., Rousseau, P., Celesia, G. G. and Siegel, G.: Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch. Neurol. 57: 1439-1443, 2000.
-
(2000)
Arch. Neurol.
, vol.57
, pp. 1439-1443
-
-
Wolozin, B.1
Kellman, W.2
Rousseau, P.3
Celesia, G.G.4
Siegel, G.5
-
409
-
-
0035169490
-
Genetically engineered models relevant to neurodegenerative disorders: Their value for understanding disease mechanisms and designing/testing experimental therapeutics
-
Wong, P. C., Cai, H., Borchelt, D. R. and Price, D. L.: Genetically engineered models relevant to neurodegenerative disorders: Their value for understanding disease mechanisms and designing/testing experimental therapeutics. J. Mol. Neurosci. 17(2): 233- 257, 2001.
-
(2001)
J. Mol. Neurosci.
, vol.17
, Issue.2
, pp. 233-257
-
-
Wong, P.C.1
Cai, H.2
Borchelt, D.R.3
Price, D.L.4
-
410
-
-
34147148973
-
Neurobiology of alzheimer's disease
-
G. J. Siegel, R. N. Albers, S. T. Brady, D. L. Price, Eds. 7th edition, Chap. 47, London: Elsevier/Academic Press
-
Wong, P. L., Li, T. and Price, D.L.: Neurobiology of Alzheimer's Disease. In: "Basic Neurochemistry: Molecular, Cellular and Medical Aspects Aspects, " G. J. Siegel, R. N. Albers, S. T. Brady, D. L. Price, Eds., 7th edition, Chap. 47, London: Elsevier/Academic Press, 2006.
-
(2006)
Basic Neurochemistry: Molecular, Cellular and Medical Aspects Aspects
-
-
Wong, P.L.1
Li, T.2
Price, D.L.3
-
411
-
-
0035909112
-
Judging a protein by more than its name: GSK-3
-
Woodgett, J. R.: Judging a protein by more than its name: GSK-3. Sci STKE. 2001(100): RE12, 2001.
-
(2001)
Sci STKE.
, vol.2001
, Issue.100
, pp. RE12
-
-
Woodgett, J.R.1
-
412
-
-
0024315598
-
Nerve growth factor receptor is associated with cholinergic neurons of the basal forebrain but not the pontomesencephalon
-
Woolf, N. J., Gould, E. and Butcher, L. L.: Nerve growth factor receptor is associated with cholinergic neurons of the basal forebrain but not the pontomesencephalon. Neuroscience 30: 30-45, 1989.
-
(1989)
Neuroscience
, vol.30
, pp. 30-45
-
-
Woolf, N.J.1
Gould, E.2
Butcher, L.L.3
-
413
-
-
0031034679
-
Tyrosine kinase receptors concentrated in caveolae-like domains from neuronal plasma membrane
-
Wu, C., Butz, S., Ying, Y. and Anderson, R. G.: Tyrosine kinase receptors concentrated in caveolae-like domains from neuronal plasma membrane. J. Biol. Chem. 272(6): 3554-3559, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.6
, pp. 3554-3559
-
-
Wu, C.1
Butz, S.2
Ying, Y.3
Anderson, R.G.4
-
414
-
-
0021977076
-
Alzheimer's disease
-
Wurtman, R. J.: Alzheimer's disease. Sci. Amer. 252: 62-74, 1985.
-
(1985)
Sci. Amer.
, vol.252
, pp. 62-74
-
-
Wurtman, R.J.1
-
415
-
-
0345059945
-
Cholinesterase inhibitor therapies and neuropsychiatric manifestations of Alzheimer's disease
-
Wynn, Z. J. and Cummings, J. L.: Cholinesterase inhibitor therapies and neuropsychiatric manifestations of Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 17: 100-108, 2004.
-
(2004)
Dement. Geriatr. Cogn. Disord.
, vol.17
, pp. 100-108
-
-
Wynn, Z.J.1
Cummings, J.L.2
-
416
-
-
0346881214
-
PET quantification of muscarinic cholinergic receptors with [N-metyl]-benztropine and application to studies of propofol-induced unconsciousness in healthy human volunteers
-
Xie, G., Gunn, R. N., Dagher, A., Daloze, T., Plourde, G., Backman, S. B., Diksic, I. and Fiset, P.: PET quantification of muscarinic cholinergic receptors with [N-metyl]-benztropine and application to studies of propofol-induced unconsciousness in healthy human volunteers. Synapse 51: 91-101, 2004.
-
(2004)
Synapse
, vol.51
, pp. 91-101
-
-
Xie, G.1
Gunn, R.N.2
Dagher, A.3
Daloze, T.4
Plourde, G.5
Backman, S.B.6
Diksic, I.7
Fiset, P.8
-
417
-
-
0034671727
-
Subunit structure of a mammalian ER/Golgi SNARE complex
-
Xu, D., Joglekar, A. P., Williams, A. L. and Hay, J. C.: Subunit structure of a mammalian ER/Golgi SNARE complex. J. Biol. Chem. 275(50): 39631-39639, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.50
, pp. 39631-39639
-
-
Xu, D.1
Joglekar, A.P.2
Williams, A.L.3
Hay, J.C.4
-
418
-
-
0035830844
-
Accumulation and aggregation of amyloid betaprotein in late endosomes of Niemann-pick type C cells
-
Yamazaki, T., Chang, T. Y., Haass, C. and Ihara, Y.: Accumulation and aggregation of amyloid betaprotein in late endosomes of Niemann-pick type C cells. J. Biol. Chem. 276: 4454-4460, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4454-4460
-
-
Yamazaki, T.1
Chang, T.Y.2
Haass, C.3
Ihara, Y.4
-
419
-
-
0033518264
-
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity
-
Yan, R., Bienkowski, M. J., Shuck, M. E., Miao, H., Tory, M. C., Pauley, A. M., Brashier, J. R., Stratman, N. C., Mathews, W. R., Buhl, A. E., Carter, D. B., Tomasselli, A. G., Parodi, L. A., Heinrikson, R. L. and Gurney, M. E.: Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity. Nature 402(6761): 533-537, 1999.
-
(1999)
Nature
, vol.402
, Issue.6761
, pp. 533-537
-
-
Yan, R.1
Bienkowski, M.J.2
Shuck, M.E.3
Miao, H.4
Tory, M.C.5
Pauley, A.M.6
Brashier, J.R.7
Stratman, N.C.8
Mathews, W.R.9
Buhl, A.E.10
Carter, D.B.11
Tomasselli, A.G.12
Parodi, L.A.13
Heinrikson, R.L.14
Gurney, M.E.15
-
420
-
-
0028885854
-
GM1 ganglioside-bound amyloid beta-protein (A beta): A possible form of preamyloid in Alzheimer's disease
-
Yanagisawa, K., Odaka, A., Suzuki, N. and Ihara, Y.: GM1 ganglioside-bound amyloid beta-protein (A beta): A possible form of preamyloid in Alzheimer's disease. Nat. Med. 1(10): 1062-1066, 1995.
-
(1995)
Nat. Med.
, vol.1
, Issue.10
, pp. 1062-1066
-
-
Yanagisawa, K.1
Odaka, A.2
Suzuki, N.3
Ihara, Y.4
-
421
-
-
0035118736
-
Amyloid-beta peptide assembly: A critical step in fibrillogenesis and membrane disruption
-
Yip, C. M. and McLaurin, J.: Amyloid-beta peptide assembly: A critical step in fibrillogenesis and membrane disruption. Biophys. J. 80(3): 1359-1371, 2001.
-
(2001)
Biophys. J.
, vol.80
, Issue.3
, pp. 1359-1371
-
-
Yip, C.M.1
McLaurin, J.2
-
422
-
-
0035943343
-
Cholesterol, a modulator of membrane-associated Abeta-fibrillogenesis and neurotoxicity
-
Yip, C. M., Elton, E. A., Darabie, A. A., Morrison, M. R. and McLaurin, J.: Cholesterol, a modulator of membrane-associated Abeta-fibrillogenesis and neurotoxicity. J. Mol. Biol. 311(4): 723-734, 2001.
-
(2001)
J. Mol. Biol.
, vol.311
, Issue.4
, pp. 723-734
-
-
Yip, C.M.1
Elton, E.A.2
Darabie, A.A.3
Morrison, M.R.4
McLaurin, J.5
-
423
-
-
0037931149
-
Specific compositions of amyloidbeta peptides as the determinant of toxic betaaggregation
-
Yoshiike, Y., Chui, D. H., Akagi, T., Tanaka, N. and Takashima, A.: Specific compositions of amyloidbeta peptides as the determinant of toxic betaaggregation. J. Biol. Chem. 278(26): 23648-23655, 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.26
, pp. 23648-23655
-
-
Yoshiike, Y.1
Chui, D.H.2
Akagi, T.3
Tanaka, N.4
Takashima, A.5
-
424
-
-
11844297771
-
GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity
-
Yoshimura, T., Kawano, Y., Arimura, N., Kawabata, N., et al.: GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity. Cell 120: 137-149, 2005.
-
(2005)
Cell
, vol.120
, pp. 137-149
-
-
Yoshimura, T.1
Kawano, Y.2
Arimura, N.3
Kawabata, N.4
-
425
-
-
0033145416
-
Caspase activity sows the seeds of neuronal death
-
Yuan, J. and Yankner, B. A.: Caspase activity sows the seeds of neuronal death. Nat. Cell Biol. 1(2): E44-45, 1999.
-
(1999)
Nat. Cell Biol.
, vol.1
, Issue.2
, pp. E44-E45
-
-
Yuan, J.1
Yankner, B.A.2
-
426
-
-
0037130576
-
Biochemical and immunocytochemical characterization of calsenilin in mouse brain
-
Zaidi, N. F., Berezovska, O., Choi, E. K., Miller, J. S., Chan, H., Lilliehook, C., Hyman, B. T., Buxbaum, J. D. and Wasco, W.: Biochemical and immunocytochemical characterization of calsenilin in mouse brain. Neuroscience 114(1): 247-263, 2002.
-
(2002)
Neuroscience
, vol.114
, Issue.1
, pp. 247-263
-
-
Zaidi, N.F.1
Berezovska, O.2
Choi, E.K.3
Miller, J.S.4
Chan, H.5
Lilliehook, C.6
Hyman, B.T.7
Buxbaum, J.D.8
Wasco, W.9
-
427
-
-
0019433761
-
Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification
-
Zannis, V. I. and Breslow, J. L.: Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification. Biochemistry 20(4): 1033-1041, 1981.
-
(1981)
Biochemistry
, vol.20
, Issue.4
, pp. 1033-1041
-
-
Zannis, V.I.1
Breslow, J.L.2
-
428
-
-
13244264765
-
A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons
-
Zheng, Y.-L., Kesavapany, S., Gravell, M., Hamilton, R. S., et al.: A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons. The EMBO Journal 24: 209-220, 2005.
-
(2005)
The EMBO Journal
, vol.24
, pp. 209-220
-
-
Zheng, Y.-L.1
Kesavapany, S.2
Gravell, M.3
Hamilton, R.S.4
-
429
-
-
0026049539
-
Generalized amyloidosis from beta 2-microglobulin, with caecal perforation after long-term haemodialysis
-
Zhou, H., Pfeifer, U. and Linke, R.: Generalized amyloidosis from beta 2-microglobulin, with caecal perforation after long-term haemodialysis. Virchows Arch. A Pathol. Anat. Histopathol. 419(4): 349-353, 1991.
-
(1991)
Virchows Arch. A Pathol. Anat. Histopathol.
, vol.419
, Issue.4
, pp. 349-353
-
-
Zhou, H.1
Pfeifer, U.2
Linke, R.3
-
430
-
-
0036770144
-
The role of mitogen-activated protein kinase pathways in Alzheimer's disease
-
Zhu, X., Lee, H. G., Raina, A. K., Perry, G. and Smith, M. A.: The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals 11(5): 270-281, 2002.
-
(2002)
Neurosignals
, vol.11
, Issue.5
, pp. 270-281
-
-
Zhu, X.1
Lee, H.G.2
Raina, A.K.3
Perry, G.4
Smith, M.A.5
-
431
-
-
4544239545
-
Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines
-
Zimmermann, M., Gardoni, F., Marcello, E., Colciaghi, F., Borroni, B., Pardovani, A., Cattabeni, F. and Di Luca, M.: Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines. J. Neurochem. 90: 1489- 1499, 2004.
-
(2004)
J. Neurochem.
, vol.90
, pp. 1489-1499
-
-
Zimmermann, M.1
Gardoni, F.2
Marcello, E.3
Colciaghi, F.4
Borroni, B.5
Pardovani, A.6
Cattabeni, F.7
Di Luca, M.8
|