PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1

Journal of Biological Chemistry

Volumn 278, Issue 10, 2003, Pages 7850-7854

  Luo, Wen jie ^a   Wang, Hong ^a   Li, Hongqiao ^b   Kim, Benny S ^a   Shah, Sanjiv ^b   Lee, Hahn Jun ^c   Thinakaran, Gopal ^d   Kim, Tae Wan ^c   Yu, Gang ^b   Xu, Huaxi ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c Columbia University ^*  (United States)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME KINETICS; PROTEINS; RNA; SIGNALING;

PROTEOLYSIS;

BIOCHEMISTRY;

ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; GAMMA SECRETASE; NICASTRIN; PRESENILIN 1; PRESENILIN 2; PROTEIN; PROTEIN PEN 2; RNA; UNCLASSIFIED DRUG; APH 1 PROTEIN, HUMAN; APH-1 PROTEIN, HUMAN; MEMBRANE PROTEIN; PRIMER DNA; PSEN1 PROTEIN, HUMAN; PSENEN PROTEIN, HUMAN; SECRETASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BIOGENESIS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; ANIMAL; CELL CULTURE; HYDROLYSIS; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ANIMALIA;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BASE SEQUENCE; DNA PRIMERS; HYDROLYSIS; MEMBRANE PROTEINS; MICE; PRESENILIN-1; PROTEIN PROCESSING, POST-TRANSLATIONAL; TUMOR CELLS, CULTURED;

EID: 0037424275     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C200648200     Document Type: Article

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