Retention of the Alzheimer's Amyloid Precursor Fragment C99 in the Endoplasmic Reticulum Prevents Formation of Amyloid β-Peptide

Journal of Biological Chemistry

Volumn 276, Issue 23, 2001, Pages 20267-20279

  Maltese, William A ^a   Wilson, Susan ^a   Tan, Yizheng ^b   Suomensaari, Susanna ^c   Sinha, Sukanto ^c   Barbour, Robin ^c   McConlogue, Lisa ^c  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c ELAN PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CATALYSIS; CELLS; DISEASES; ENZYMES;

ENDOPLASMIC RETICULUM;

BIOCHEMISTRY;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; GUANOSINE TRIPHOSPHATASE; LYSINE; MEMBRANE ENZYME; MEMBRANE PROTEIN; PRESENILIN 1; PROTEIN RAB1B; PROTEINASE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME MECHANISM; GOLGI COMPLEX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN SECRETION; CELL FRACTIONATION; CHEMISTRY; METABOLISM;

ALZHEIMER DISEASE; AMINO ACID MOTIFS; AMYLOID BETA-PROTEIN PRECURSOR; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; HUMANS; LYSINE; PEPTIDE FRAGMENTS; SUBCELLULAR FRACTIONS;

EID: 0035827702     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M007238200     Document Type: Article

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