-
1
-
-
0030667339
-
α-Secretase-derived product of β-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease
-
Ancolio K., Murambaud P., Dauch P., and Checler F. (1997) α-Secretase-derived product of β-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease. J. Neurochem. 69, 2494-2499.
-
(1997)
J. Neurochem.
, vol.69
, pp. 2494-2499
-
-
Ancolio, K.1
Murambaud, P.2
Dauch, P.3
Checler, F.4
-
2
-
-
0025831751
-
Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells
-
Anderson J. P., Esch F. S., Keim P. S., Sambamurti K., Lieberburg I., and Robakis N. K. (1991) Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells. Neurosci. Lett. 128, 126-128.
-
(1991)
Neurosci. Lett.
, vol.128
, pp. 126-128
-
-
Anderson, J.P.1
Esch, F.S.2
Keim, P.S.3
Sambamurti, K.4
Lieberburg, I.5
Robakis, N.K.6
-
3
-
-
0026545684
-
An alternative secretase cleavage produces soluble Alzheimer amyloid precursor protein containing a potentially amyloidogenic sequence
-
Anderson J. P., Chen Y., Kim K. S., and Robakis N. K. (1992) An alternative secretase cleavage produces soluble Alzheimer amyloid precursor protein containing a potentially amyloidogenic sequence. J. Neurochem. 59, 2328-2331.
-
(1992)
J. Neurochem.
, vol.59
, pp. 2328-2331
-
-
Anderson, J.P.1
Chen, Y.2
Kim, K.S.3
Robakis, N.K.4
-
4
-
-
14444267540
-
Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid β peptides: Their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases
-
Barelli H., Lebeau A., Vizzuvona J., Delaere P., Chevallier N., Drouot C., Marambaud P., Ancolio K., Buxbaum J. D., Khorkova O., Heroux J., Sahasrabudhe S., Martinez J., Warter J. M., Mohr M., and Checler F. (1997) Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid β peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases. Mol. Med. 3, 695-707.
-
(1997)
Mol. Med.
, vol.3
, pp. 695-707
-
-
Barelli, H.1
Lebeau, A.2
Vizzuvona, J.3
Delaere, P.4
Chevallier, N.5
Drouot, C.6
Marambaud, P.7
Ancolio, K.8
Buxbaum, J.D.9
Khorkova, O.10
Heroux, J.11
Sahasrabudhe, S.12
Martinez, J.13
Warter, J.M.14
Mohr, M.15
Checler, F.16
-
5
-
-
0030222080
-
Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor
-
Barger S. W. and Mattson M. P. (1996) Induction of neuroprotective κB-dependent transcription by secreted forms of the Alzheimer's β-amyloid precursor. Mol. Brain Res. 40, 116-126.
-
(1996)
Mol. Brain Res.
, vol.40
, pp. 116-126
-
-
Barger, S.W.1
Mattson, M.P.2
-
6
-
-
0028912956
-
Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of β-amyloid precursor
-
Barger S. W., Fiscus R. R., Ruth P., Hofmann F., and Mattson M. P. (1995) Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of β-amyloid precursor. J. Neurochem. 64, 2087-2096.
-
(1995)
J. Neurochem.
, vol.64
, pp. 2087-2096
-
-
Barger, S.W.1
Fiscus, R.R.2
Ruth, P.3
Hofmann, F.4
Mattson, M.P.5
-
7
-
-
0025800016
-
Increased release of an amyloidogenic C-terminal Alzheimer amyloid precursor protein fragment from stressed PC-12 cells
-
Baskin F., Rosenberg R. N., and Greenberg B. D. (1991) Increased release of an amyloidogenic C-terminal Alzheimer amyloid precursor protein fragment from stressed PC-12 cells. J. Neurosci. Res. 29, 127-132.
-
(1991)
J. Neurosci. Res.
, vol.29
, pp. 127-132
-
-
Baskin, F.1
Rosenberg, R.N.2
Greenberg, B.D.3
-
8
-
-
0032498135
-
Specific role for protein kinase Cα in the constitutive and regulated secretion of amyloid precursor protein in human skin fibroblasts
-
Benussi L., Govoni S., Gasparini L., Binetti G., Trabucchi M., Bianchetti A., and Racchi M. (1998) Specific role for protein kinase Cα in the constitutive and regulated secretion of amyloid precursor protein in human skin fibroblasts. Neurosci. Lett. 240, 97-101.
-
(1998)
Neurosci. Lett.
, vol.240
, pp. 97-101
-
-
Benussi, L.1
Govoni, S.2
Gasparini, L.3
Binetti, G.4
Trabucchi, M.5
Bianchetti, A.6
Racchi, M.7
-
9
-
-
0029671454
-
Cholestrol modulates α-secretase cleavage of amyloid precursor protein
-
Bodovitz S. and Klein W. L. (1996) Cholestrol modulates α-secretase cleavage of amyloid precursor protein. J. Biol. Chem. 271, 4436-4440.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
10
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ1-42/1-40 ratio in vitro and in vivo
-
Borchelt D. R., Thinakaren G., Eckman C. B., Lee M. K., Davenport F., Ratovitsky T., Prada C.-M., Kim G., Seekins S., Yager D., Slunt H. H., Wang R., Seeger M., Levey A. I., Gandy S. E., Copeland N. G., Jenkins N. A., Price D. L., Younkin S. G., and Sisodia S. S. (1996) Familial Alzheimer's disease-linked presenilin 1 variants elevate Aβ1-42/1-40 ratio in vitro and in vivo. Neuron 17, 1005-1013.
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaren, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.-M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Wang, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
11
-
-
0028114869
-
Reduction of neurological damage by a peptide segment of the amyloid β-A4 protein precursor in rabbit spinal cord ischemic model
-
Bowes M., Masliah E., Otero D., Zivin J., and Saitoh T. (1994) Reduction of neurological damage by a peptide segment of the amyloid β-A4 protein precursor in rabbit spinal cord ischemic model. Exp. Neurol. 129, 112-119.
-
(1994)
Exp. Neurol.
, vol.129
, pp. 112-119
-
-
Bowes, M.1
Masliah, E.2
Otero, D.3
Zivin, J.4
Saitoh, T.5
-
12
-
-
0028167193
-
Confirmation of the ∈4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease
-
Brousseau T., Legrain S., Berr C., Gourlet V., Vidal O., and Amouyel P. (1994) Confirmation of the ∈4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease. Neurology 44, 342-344.
-
(1994)
Neurology
, vol.44
, pp. 342-344
-
-
Brousseau, T.1
Legrain, S.2
Berr, C.3
Gourlet, V.4
Vidal, O.5
Amouyel, P.6
-
13
-
-
0022549920
-
A receptor-mediated pathway lor cholesterol homeostasis
-
Brown M. S. and Goldstein J. L. (1986) A receptor-mediated pathway lor cholesterol homeostasis. Science 232, 34-47.
-
(1986)
Science
, vol.232
, pp. 34-47
-
-
Brown, M.S.1
Goldstein, J.L.2
-
14
-
-
0030941803
-
The SREP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown M. S. and Goldstein J. L. (1997) The SREP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89, 331-340.
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
15
-
-
0027407570
-
Generation of β-amyloid in the secretory pathway in neuronal and nonneuronal cells
-
Busciglio J., Gabuzda D. H., Matsudaira P., and Yanker B. A. (1993) Generation of β-amyloid in the secretory pathway in neuronal and nonneuronal cells. Proc. Natl. Acad. Sci. USA 90, 2092-2096.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2092-2096
-
-
Busciglio, J.1
Gabuzda, D.H.2
Matsudaira, P.3
Yanker, B.A.4
-
16
-
-
0029983525
-
Regulation of APP processing by intra- and intercellular signals
-
Buxbaum J. D. and Greengard P. (1996) Regulation of APP processing by intra- and intercellular signals. Ann. NY Acad. Sci. 777, 327-331.
-
(1996)
Ann. NY Acad. Sci.
, vol.777
, pp. 327-331
-
-
Buxbaum, J.D.1
Greengard, P.2
-
17
-
-
0025296205
-
Processing of Alzheimer β/A4 amyloid precursor protein: Modulation by agents that regulate protein phosphorylation
-
Buxbaum J. D., Gandy S. E., Cicchetti P., Ehrlich M. E., Czernik A. J., Fracasso R. P., Ramabhadran T. V., Unterbeck A. J., and Greengard P. (1990) Processing of Alzheimer β/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation. Proc. Natl. Acad. Sci. USA 87, 6003-6006.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6003-6006
-
-
Buxbaum, J.D.1
Gandy, S.E.2
Cicchetti, P.3
Ehrlich, M.E.4
Czernik, A.J.5
Fracasso, R.P.6
Ramabhadran, T.V.7
Unterbeck, A.J.8
Greengard, P.9
-
18
-
-
0026448114
-
Cholinergic agonists and interleukin 1 regulate processing and release of the Alzheimer β/A4 amyloid protein precursor
-
Buxbaum J. D., Oishi M., Chen H. I., Pinkas-Kramarski R., Jaffe E. A., Gandy S. E., and Greengard P. (1992) Cholinergic agonists and interleukin 1 regulate processing and release of the Alzheimer β/A4 amyloid protein precursor. Proc. Natl. Acad. Sci. USA 89, 10075-10078.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10075-10078
-
-
Buxbaum, J.D.1
Oishi, M.2
Chen, H.I.3
Pinkas-Kramarski, R.4
Jaffe, E.A.5
Gandy, S.E.6
Greengard, P.7
-
19
-
-
0027435535
-
Protein phosphorylation inhibits production of Alzheimer amyloid β/A4 peptide
-
Buxbaum J. D., Koo E. H., and Greengard P. (1993) Protein phosphorylation inhibits production of Alzheimer amyloid β/A4 peptide. Proc. Natl. Acad Sci. USA 90, 9195-9198.
-
(1993)
Proc. Natl. Acad Sci. USA
, vol.90
, pp. 9195-9198
-
-
Buxbaum, J.D.1
Koo, E.H.2
Greengard, P.3
-
20
-
-
0028207004
-
Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner
-
Buxbaum J. D., Ruefli A. A., Parker C. A., Cypess A. A., and Greengard P. (1994) Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner. Proc. Natl. Acad. Sci. USA 91, 4489-4493.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4489-4493
-
-
Buxbaum, J.D.1
Ruefli, A.A.2
Parker, C.A.3
Cypess, A.A.4
Greengard, P.5
-
21
-
-
0027526419
-
Release of excess amyloid β protein from a mutant amyloid β protein precursor
-
Cai X.-D., Golde T. E., and Younkin G. S. (1993) Release of excess amyloid β protein from a mutant amyloid β protein precursor. Science 259, 514-516.
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.-D.1
Golde, T.E.2
Younkin, G.S.3
-
22
-
-
0026545267
-
Protein phosphorylation regulates secretion of Alzheimer β/A4 amyloid precursor protein
-
Caporaso G. L., Gandy S. E., Buxbaum J. D., Ramabhadran T. V., and Greengard P. (1992) Protein phosphorylation regulates secretion of Alzheimer β/A4 amyloid precursor protein. Proc. Natl. Acad. Sci. USA 89, 3055-3059.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 3055-3059
-
-
Caporaso, G.L.1
Gandy, S.E.2
Buxbaum, J.D.3
Ramabhadran, T.V.4
Greengard, P.5
-
23
-
-
0030921730
-
Increased secretion of the amino-terminal fragment of amyloid precursor protein in brains of rats with a constitutive up-regulation of protein kinase C
-
Caputi A., Barindelli S., Pastorino L., Cimino M., Buxbaum J. D., Cattabeni F., and Di Luca M. (1997) Increased secretion of the amino-terminal fragment of amyloid precursor protein in brains of rats with a constitutive up-regulation of protein kinase C. J. Neurochem. 68, 2523-2529.
-
(1997)
J. Neurochem.
, vol.68
, pp. 2523-2529
-
-
Caputi, A.1
Barindelli, S.2
Pastorino, L.3
Cimino, M.4
Buxbaum, J.D.5
Cattabeni, F.6
Di Luca, M.7
-
24
-
-
0029379605
-
Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease
-
Checler F. (1995) Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease. J. Neurochem. 65, 1431-1444.
-
(1995)
J. Neurochem.
, vol.65
, pp. 1431-1444
-
-
Checler, F.1
-
25
-
-
0026745610
-
Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-amyloid production
-
Citron M., Oltersdorf T., Haass C., McConlogue L., Hung A. Y., Seubert P., Vigo-Pelfrey C., Lieberburg I., and Selkoe D. J. (1992) Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-amyloid production. Nature 360, 672-674.
-
(1992)
Nature
, vol.360
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
26
-
-
0028924248
-
Generation of amyloid β protein from its precursor is sequence specific
-
Citron M., Teplow D. B., and Selkoe D. J. (1995) Generation of amyloid β protein from its precursor is sequence specific. Neuron 14, 661-670.
-
(1995)
Neuron
, vol.14
, pp. 661-670
-
-
Citron, M.1
Teplow, D.B.2
Selkoe, D.J.3
-
27
-
-
0029803744
-
Evidence that the 42- and 40-amino acid forms of amyloid β protein are generated from the β-amyloid precursor protein by different protease activities
-
Citron M., Diehl T. S., Gordon G., Biere A. L., Seubert P., and Selkoe D. J. (1996) Evidence that the 42- and 40-amino acid forms of amyloid β protein are generated from the β-amyloid precursor protein by different protease activities. Proc. Natl. Acad. Sci. USA 93, 13170-13175.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13170-13175
-
-
Citron, M.1
Diehl, T.S.2
Gordon, G.3
Biere, A.L.4
Seubert, P.5
Selkoe, D.J.6
-
28
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
-
Citron M., Westaway D., Xia W., Carlson G., Diehl T., Levesque G., Johnson-Wood K., Lee M., Seubert P., Davis A., Kholodenko D., Motter R., Sherrington R., Perry B., Yao H., Strome R., Lieberburg I., Rommens J., Kim S., Schenk D., Fraser P., St. George-Hyslop P., and Selkoe D. J. (1997) Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice. Nat. Med. 3, 67-72.
-
(1997)
Nat. Med.
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St. George-Hyslop, P.22
Selkoe, D.J.23
more..
-
29
-
-
0028292343
-
Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants
-
Clarris H. J., Nurcombe V., Small D. H., Beyreuther K., and Masters C. L. (1994) Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants. J. Neurosci. 38, 248-258.
-
(1994)
J. Neurosci.
, vol.38
, pp. 248-258
-
-
Clarris, H.J.1
Nurcombe, V.2
Small, D.H.3
Beyreuther, K.4
Masters, C.L.5
-
30
-
-
0029812077
-
Expression and analysis of presenilin 1 in a human neuronal system: Localization in cell bodies and dendrites
-
Cook D. G., Sung J. C., Golde T. E., Felsenstein K. M., Wojcyk B. S., Tanzi R. E., Trojanowski J. Q., Lee V. M., and Doms R. W. (1996) Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites. Proc. Natl. Acad. Sci. USA 93, 9223-9228.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9223-9228
-
-
Cook, D.G.1
Sung, J.C.2
Golde, T.E.3
Felsenstein, K.M.4
Wojcyk, B.S.5
Tanzi, R.E.6
Trojanowski, J.Q.7
Lee, V.M.8
Doms, R.W.9
-
31
-
-
0030769092
-
Alzheimer's A β (1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
-
Cook D. G., Forman M. S., Sung J. C., Leight S., Kolson D. L., Iwatsubo T., Lee V. M.-L., and Doms R. W. (1997) Alzheimer's A β (1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells. Nat. Med. 3, 1021-1023.
-
(1997)
Nat. Med.
, vol.3
, pp. 1021-1023
-
-
Cook, D.G.1
Forman, M.S.2
Sung, J.C.3
Leight, S.4
Kolson, D.L.5
Iwatsubo, T.6
Lee, V.M.-L.7
Doms, R.W.8
-
32
-
-
0028174973
-
β-Amyloid formation as a potential therapeutic target for Alzheimer's disease
-
Cordell B. (1994) β-Amyloid formation as a potential therapeutic target for Alzheimer's disease. Annu. Rev. Pharmacol. Toxicol. 34, 69-89.
-
(1994)
Annu. Rev. Pharmacol. Toxicol.
, vol.34
, pp. 69-89
-
-
Cordell, B.1
-
33
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder E. H., Saunders A. M., Strittmatter W. J., Schmechel D. E., Gaskell P. C., Small G. W., Roses A. D., Haines J. L., and Pericak-Vance M. A. (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261, 921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
34
-
-
0020376564
-
Effects of lipids on acetylcholine receptor. Essential need of cholesterol for maintenance of agonist-induced state transitions in lipid vesicles
-
Criado M., Eibl H., and Barrantes F. J. (1982) Effects of lipids on acetylcholine receptor. Essential need of cholesterol for maintenance of agonist-induced state transitions in lipid vesicles. Biochemistry 21, 3622-3629.
-
(1982)
Biochemistry
, vol.21
, pp. 3622-3629
-
-
Criado, M.1
Eibl, H.2
Barrantes, F.J.3
-
35
-
-
0027360352
-
Regulated cleavage of Alzheimer β-amyloid precursor protein in the absence of the cytoplasmic tail
-
da Cruz e Silva O. A. B., Iverfeldt K., Oltersdorf T., Sinha S., Lieberburg I., Ramabhadran T. V., Suzuki T., Sisodia S. S., Gandy S., and Greengard P. (1993) Regulated cleavage of Alzheimer β-amyloid precursor protein in the absence of the cytoplasmic tail. Neuroscience 57, 873-877.
-
(1993)
Neuroscience
, vol.57
, pp. 873-877
-
-
Da Cruz E Silva, O.A.B.1
Iverfeldt, K.2
Oltersdorf, T.3
Sinha, S.4
Lieberburg, I.5
Ramabhadran, T.V.6
Suzuki, T.7
Sisodia, S.S.8
Gandy, S.9
Greengard, P.10
-
36
-
-
0028027214
-
Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid β-protein precursor
-
Davis-Salinas J., Saporito-Irwin S. M., Donovan F. M., Cunningham D. D., and Van Nostrand W. E. N. (1994) Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid β-protein precursor. J. Biol. Chem. 269, 22623-22627.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 22623-22627
-
-
Davis-Salinas, J.1
Saporito-Irwin, S.M.2
Donovan, F.M.3
Cunningham, D.D.4
Van Nostrand, W.E.N.5
-
37
-
-
0025269152
-
Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlations with cognitive severity
-
Dekosky S. T. and Scheff S. W. (1990) Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlations with cognitive severity. Ann. Neurol. 27, 457-464.
-
(1990)
Ann. Neurol.
, vol.27
, pp. 457-464
-
-
Dekosky, S.T.1
Scheff, S.W.2
-
38
-
-
0031952526
-
Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade
-
Desdouits-Magnen J., Desdouits F., Takeda S., Syu L.-J., Saltiel A. R., Buxbaum J. D., Czernik A. J., Nairn A. C., and Greengard P. (1998) Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade. J. Neurochem. 70, 524-530.
-
(1998)
J. Neurochem.
, vol.70
, pp. 524-530
-
-
Desdouits-Magnen, J.1
Desdouits, F.2
Takeda, S.3
Syu, L.-J.4
Saltiel, A.R.5
Buxbaum, J.D.6
Czernik, A.J.7
Nairn, A.C.8
Greengard, P.9
-
39
-
-
0027529491
-
Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): Cleavage of APP occurs in a late compartment of the default secretion pathway
-
De Strooper B., Umans L., Van Leuven F., and Van der Berghe H. (1993) Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway. J. Cell Biol. 121, 295-304.
-
(1993)
J. Cell Biol.
, vol.121
, pp. 295-304
-
-
De Strooper, B.1
Umans, L.2
Van Leuven, F.3
Van Der Berghe, H.4
-
40
-
-
0028892096
-
Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence
-
De Strooper B., Simons M., Multhaup G., Leuven F. V., Beyreuther K., and Dotti C. G. (1995) Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence. EMBO J. 14, 4932-4938.
-
(1995)
EMBO J
, vol.14
, pp. 4932-4938
-
-
De Strooper, B.1
Simons, M.2
Multhaup, G.3
Leuven, F.V.4
Beyreuther, K.5
Dotti, C.G.6
-
41
-
-
0027956042
-
Amyloid precursor protein secretion and βA4 amyloid generation are not mutually exclusive
-
Dyrks T., Monning U., Beyreuther K., and Turner J. (1994) Amyloid precursor protein secretion and βA4 amyloid generation are not mutually exclusive. FEBS Lett. 349, 210-214.
-
(1994)
FEBS Lett.
, vol.349
, pp. 210-214
-
-
Dyrks, T.1
Monning, U.2
Beyreuther, K.3
Turner, J.4
-
42
-
-
0028296661
-
Study of the phorbol ester effect on Alzheimer amyloid precursor processing: Sequence requirements and involvement of cholera toxin sensitive protein
-
Efthimiopoulos S., Felsenstein K. M., Sambamurti K., Robakis N. K., and Refolo L. M. (1994) Study of the phorbol ester effect on Alzheimer amyloid precursor processing: sequence requirements and involvement of cholera toxin sensitive protein. J. Neurosci. Res. 38, 81-90.
-
(1994)
J. Neurosci. Res.
, vol.38
, pp. 81-90
-
-
Efthimiopoulos, S.1
Felsenstein, K.M.2
Sambamurti, K.3
Robakis, N.K.4
Refolo, L.M.5
-
43
-
-
0030035594
-
Intracellular cyclic AMP inhibits constitutive and phorbol ester-stimulated secretory cleavage of amyloid precursor protein
-
Efthimiopoulos S., Punji S., Manolopoulos V., Pangalos M., Wang G. P., Refolo L. M., and Robakis N. K. (1996) Intracellular cyclic AMP inhibits constitutive and phorbol ester-stimulated secretory cleavage of amyloid precursor protein. J. Neurochem. 67, 872-875.
-
(1996)
J. Neurochem.
, vol.67
, pp. 872-875
-
-
Efthimiopoulos, S.1
Punji, S.2
Manolopoulos, V.3
Pangalos, M.4
Wang, G.P.5
Refolo, L.M.6
Robakis, N.K.7
-
45
-
-
0027396773
-
WAL 2014 - A muscarinic agonist with preferential neuron-stimulating properties
-
Ensinger H. A., Doods H. N., Immel-Sehr A. R., Kuhn F. J., Lambrecht G., Mendia K. D., Muller R. E., Mutschler E., Sagrada A., Walther G., and Hammer R. (1993) WAL 2014 - a muscarinic agonist with preferential neuron-stimulating properties. Life Sci. 2, 473-480.
-
(1993)
Life Sci.
, vol.2
, pp. 473-480
-
-
Ensinger, H.A.1
Doods, H.N.2
Immel-Sehr, A.R.3
Kuhn, F.J.4
Lambrecht, G.5
Mendia, K.D.6
Muller, R.E.7
Mutschler, E.8
Sagrada, A.9
Walther, G.10
Hammer, R.11
-
46
-
-
0025295039
-
Cleavage of β-amyloid peptide during constitutive processing of its precursor
-
Esch F. S., Keim P. S., Beattie E. C., Blacher R. W., Culwell A. R., Oltersdorf T., McClure D., and Ward P. J. (1990) Cleavage of β-amyloid peptide during constitutive processing of its precursor. Science 248, 1122-1124.
-
(1990)
Science
, vol.248
, pp. 1122-1124
-
-
Esch, F.S.1
Keim, P.S.2
Beattie, E.C.3
Blacher, R.W.4
Culwell, A.R.5
Oltersdorf, T.6
McClure, D.7
Ward, P.J.8
-
47
-
-
0026522375
-
Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor
-
Estus S., Golde T. E., Kunishita T., Blades D., Lowery D., Eisen M., Usiak M., Qu X. M., Tabira T., Greenberg B. D., and Younkin S. G. (1992) Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor. Science 255, 726-728.
-
(1992)
Science
, vol.255
, pp. 726-728
-
-
Estus, S.1
Golde, T.E.2
Kunishita, T.3
Blades, D.4
Lowery, D.5
Eisen, M.6
Usiak, M.7
Qu, X.M.8
Tabira, T.9
Greenberg, B.D.10
Younkin, S.G.11
-
48
-
-
0028971033
-
Regulated secretion of β-amyloid precursor protein in rat brain
-
Farber S. A., Nitsch R. M., Schulz J. G., and Wurtman R. J. (1995) Regulated secretion of β-amyloid precursor protein in rat brain. J. Neurosci. 15, 7442-7451.
-
(1995)
J. Neurosci.
, vol.15
, pp. 7442-7451
-
-
Farber, S.A.1
Nitsch, R.M.2
Schulz, J.G.3
Wurtman, R.J.4
-
51
-
-
0031014448
-
Ionic effects of the Alzheimer's disease β-amyloid precursor protein and its metabolic fragments
-
Fraser S. P., Suh Y.-H., and Djamgoz M. B. A. (1997) Ionic effects of the Alzheimer's disease β-amyloid precursor protein and its metabolic fragments. Trends Neurosci. 20, 67-72.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 67-72
-
-
Fraser, S.P.1
Suh, Y.-H.2
Djamgoz, M.B.A.3
-
52
-
-
0027459976
-
Nerve growth factor-induced neuronal differentiation is accompanied by differential induction and localization of the amyloid precursor protein (APP) in PC12 cells and variant PC12S cells
-
Fukuyama R., Chandrasekaran K., and Rapoport S. I. (1993) Nerve growth factor-induced neuronal differentiation is accompanied by differential induction and localization of the amyloid precursor protein (APP) in PC12 cells and variant PC12S cells. Mol. Brain Res. 17, 17-22.
-
(1993)
Mol. Brain Res.
, vol.17
, pp. 17-22
-
-
Fukuyama, R.1
Chandrasekaran, K.2
Rapoport, S.I.3
-
53
-
-
0028980783
-
Intracellular production of β3A4 amyloid of Alzheimer's disease: Modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein
-
Fuller S. J., Storey E., Li Q.-X., Smith A. I., Beyreuther K., and Masters C. L. (1995) Intracellular production of β3A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein. Biochemistry 34, 8091-8098.
-
(1995)
Biochemistry
, vol.34
, pp. 8091-8098
-
-
Fuller, S.J.1
Storey, E.2
Li, Q.-X.3
Smith, A.I.4
Beyreuther, K.5
Masters, C.L.6
-
54
-
-
0031905682
-
Secreted amyloid precursor protein a selectively suppresses N-methyl-D-aspanate currents in hippocampal neurons: Involvement of cyclic GMP
-
Furukawa K. and Mattson M. P. (1998) Secreted amyloid precursor protein a selectively suppresses N-methyl-D-aspanate currents in hippocampal neurons: involvement of cyclic GMP. Neuroscience 83, 429-438.
-
(1998)
Neuroscience
, vol.83
, pp. 429-438
-
-
Furukawa, K.1
Mattson, M.P.2
-
55
-
-
0030068094
-
+ channels and suppression of neuronal activity by secreted β-amyloid precursor protein
-
+ channels and suppression of neuronal activity by secreted β-amyloid precursor protein. Nature 379, 74-78.
-
(1996)
Nature
, vol.379
, pp. 74-78
-
-
Furukawa, K.1
Barger, S.W.2
Blalock, E.M.3
Mattson, M.P.4
-
56
-
-
0029841562
-
Increased activity-regulating and neuroprotective efficacy of α-secretase-derived secreted amyloid precursor protein is conferred by a C-terminal heparin-binding domain
-
Furukawa K., Sopher B., Rydel R. E., Begley J. G., Pham D. G., Martin G. M., Fox M., and Mattson M. P. (1996b) Increased activity-regulating and neuroprotective efficacy of α-secretase-derived secreted amyloid precursor protein is conferred by a C-terminal heparin-binding domain. J. Neurochem. 67, 1882-1896.
-
(1996)
J. Neurochem.
, vol.67
, pp. 1882-1896
-
-
Furukawa, K.1
Sopher, B.2
Rydel, R.E.3
Begley, J.G.4
Pham, D.G.5
Martin, G.M.6
Fox, M.7
Mattson, M.P.8
-
57
-
-
0027332657
-
Inhibition of β-amyloid production by activation of protein kinase C
-
Gabuzda D., Busciglio J., and Yanker B. A. (1993) Inhibition of β-amyloid production by activation of protein kinase C. J. Neurochem. 61, 2326-2329.
-
(1993)
J. Neurochem.
, vol.61
, pp. 2326-2329
-
-
Gabuzda, D.1
Busciglio, J.2
Yanker, B.A.3
-
58
-
-
0028200649
-
Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative
-
Gabuzda D., Busciglio J., Chen L. B., Matsudaira P., and Yanker B. A. (1994) Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. J. Biol. Chem. 269, 13623-13628.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13623-13628
-
-
Gabuzda, D.1
Busciglio, J.2
Chen, L.B.3
Matsudaira, P.4
Yanker, B.A.5
-
59
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., Gillespie F., Guido T., Hagopian S., Johnson-Wood K., Khan K., Lee M., Leibowitz P., Lieberburg I., Little S., Masliah E., McConlogue L., Montoya-Zavala M., Mucke L., Paganini L., Penniman E., Power M., Schenk D., Seuhert P., Snyder B., Soriano F., Tan H., Vitale J., Wadsworth S., Wolozin B., and Zhao J. (1995) Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373, 523-525.
-
(1995)
Nature
, vol.373
, pp. 523-525
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagopian, S.12
Johnson-Wood, K.13
Khan, K.14
Lee, M.15
Leibowitz, P.16
Lieberburg, I.17
Little, S.18
Masliah, E.19
McConlogue, L.20
Montoya-Zavala, M.21
Mucke, L.22
Paganini, L.23
Penniman, E.24
Power, M.25
Schenk, D.26
Seuhert, P.27
Snyder, B.28
Soriano, F.29
Tan, H.30
Vitale, J.31
Wadsworth, S.32
Wolozin, B.33
Zhao, J.34
more..
-
60
-
-
0030930721
-
Effect of energy storage and oxidative stress on amyloid precursor protein metabolism in COS cells
-
Gasparini L., Racchi M., Benussi L., Curti D., Binetti G., Bianchetti A., Trabucchi M., and Govoni S. (1997) Effect of energy storage and oxidative stress on amyloid precursor protein metabolism in COS cells. Neurosci. Lett. 231, 113-117.
-
(1997)
Neurosci. Lett.
, vol.231
, pp. 113-117
-
-
Gasparini, L.1
Racchi, M.2
Benussi, L.3
Curti, D.4
Binetti, G.5
Bianchetti, A.6
Trabucchi, M.7
Govoni, S.8
-
61
-
-
0030464044
-
New trends in cholinergic therapy for Alzheimer's disease: Nicotinic agonists or cholinesterase inhibitors
-
Giacobini E. (1996) New trends in cholinergic therapy for Alzheimer's disease: nicotinic agonists or cholinesterase inhibitors. Prog. Brain Res. 109, 311-323.
-
(1996)
Prog. Brain Res.
, vol.109
, pp. 311-323
-
-
Giacobini, E.1
-
62
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A., Chartier-Harlin M.-C., Mullan M., Brown J., Crawford F., Fidani L., Giuffra L., Haynes A., Irving N., James L., Mant R., Newton P., Rooke K., Roques P., Talbot C., Pericak-Vance M., Roses A., Williamson R., Rossor M., Owen M., and Hardy J. (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349, 704-706.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
63
-
-
0023495384
-
Neuronal localization of amyloid β protein precursor mRNA in normal human brain and in Alzheimer's disease
-
Goedert M. (1987) Neuronal localization of amyloid β protein precursor mRNA in normal human brain and in Alzheimer's disease. EMBO J. 6, 3627-3632.
-
(1987)
EMBO J
, vol.6
, pp. 3627-3632
-
-
Goedert, M.1
-
64
-
-
0027214404
-
Phosphoprotein phosphatase activities in Alzheimer disease brain
-
Gong C.-X., Singh T. J., Grundke-Iqbal I., and Iqbal K. (1993) Phosphoprotein phosphatase activities in Alzheimer disease brain. J. Neurochem. 61, 921-927.
-
(1993)
J. Neurochem.
, vol.61
, pp. 921-927
-
-
Gong, C.-X.1
Singh, T.J.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
65
-
-
0028179341
-
Chemical characterization of Aβ17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease
-
Gowing E., Roher A. E., Woods A. S., Cotter R. J., Chaney M., Little S. P., and Ball M. J. (1994) Chemical characterization of Aβ17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease. J. Biol. Chem. 269, 10987-10990.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10987-10990
-
-
Gowing, E.1
Roher, A.E.2
Woods, A.S.3
Cotter, R.J.4
Chaney, M.5
Little, S.P.6
Ball, M.J.7
-
66
-
-
0027318670
-
Induction of β-amyloid precursor protein isoform mRNAs by bFGF in astrocytes
-
Gray C. W. and Patel A. J. (1993) Induction of β-amyloid precursor protein isoform mRNAs by bFGF in astrocytes. Neuroreport 4, 811-814.
-
(1993)
Neuroreport
, vol.4
, pp. 811-814
-
-
Gray, C.W.1
Patel, A.J.2
-
67
-
-
0028179001
-
Secreted β-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances T phosphorylation
-
Greenberg S. M., Koo E. H., Selkoe D. J., Qiu W. Q., and Kosik K. S. (1994) Secreted β-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances T phosphorylation. Proc. Natl. Acad. Sci. USA 91, 7104-7108.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7104-7108
-
-
Greenberg, S.M.1
Koo, E.H.2
Selkoe, D.J.3
Qiu, W.Q.4
Kosik, K.S.5
-
68
-
-
0028980795
-
Amino-terminal region of the β-amyloid precursor protein activates mitogen-activated protein kinase
-
Greenberg S. M., Qiu W. Q., Selkoe D. J., Ben-Itzhak A., and Kosik K. S. (1995) Amino-terminal region of the β-amyloid precursor protein activates mitogen-activated protein kinase. Neurosci. Lett. 198, 52-56.
-
(1995)
Neurosci. Lett.
, vol.198
, pp. 52-56
-
-
Greenberg, S.M.1
Qiu, W.Q.2
Selkoe, D.J.3
Ben-Itzhak, A.4
Kosik, K.S.5
-
69
-
-
0026646604
-
Amyloid β-peptide is produced by cultured cells during normal metabolism
-
Haass C., Schlossmacher M. G., Hung A. Y., Vigo-Pelfrey C, Mellon A., Ostaszewski B. L., Lieberburg I., Koo E. H., Schenk D., Teplow D. B., and Selkoe D. J. (1992) Amyloid β-peptide is produced by cultured cells during normal metabolism. Nature 359, 322-325.
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostaszewski, B.L.6
Lieberburg, I.7
Koo, E.H.8
Schenk, D.9
Teplow, D.B.10
Selkoe, D.J.11
-
70
-
-
0027535111
-
β-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms
-
Haass C. Hung A. Y., Schlossmacher M. G., Teplow D. B., and Selkoe D. J. (1993) β-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms. J. Biol. Chem. 268, 3021-3024.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 3021-3024
-
-
Haass, C.1
Hung, A.Y.2
Schlossmacher, M.G.3
Teplow, D.B.4
Selkoe, D.J.5
-
71
-
-
0031052381
-
Amyloid, the presenilins and Alzheimer's disease
-
Hardy J. (1997) Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci. 20, 154-159.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 154-159
-
-
Hardy, J.1
-
72
-
-
0030769091
-
Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides
-
Hartmann T., Bieger S. C. Bruhl B., Tienari P. J., Ida N., Allsop D., Roberts G. W., Masters C. L., Dotti C. G., Unsicker K., and Beyreuther K. (1997) Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides. Nat. Med. 3, 1016-1020.
-
(1997)
Nat. Med.
, vol.3
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.C.2
Bruhl, B.3
Tienari, P.J.4
Ida, N.5
Allsop, D.6
Roberts, G.W.7
Masters, C.L.8
Dotti, C.G.9
Unsicker, K.10
Beyreuther, K.11
-
73
-
-
0028987849
-
Inhibition of β-amyloid formation identifies proteolytic precursors and subcellular sites of catabolism
-
Higaki J., Quon D., Zhong A., and Cordell B. (1995) Inhibition of β-amyloid formation identifies proteolytic precursors and subcellular sites of catabolism. Neuron 14, 651-659.
-
(1995)
Neuron
, vol.14
, pp. 651-659
-
-
Higaki, J.1
Quon, D.2
Zhong, A.3
Cordell, B.4
-
74
-
-
0031891929
-
Cerebro-spinal fluid levels of amyloid precursor protein and amyloid β-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity
-
Hock C., Golombowski S., Mullerspahn F., Naser W., Beyreuther K., Monning U., Schenk D., Vigopelfrey C., Bush A. M., Moir T., Tanzi R. E., Growdon J. H., and Nitsch R. M. (1998) Cerebro-spinal fluid levels of amyloid precursor protein and amyloid β-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity. Eur. Neurol. 39, 111-118.
-
(1998)
Eur. Neurol.
, vol.39
, pp. 111-118
-
-
Hock, C.1
Golombowski, S.2
Mullerspahn, F.3
Naser, W.4
Beyreuther, K.5
Monning, U.6
Schenk, D.7
Vigopelfrey, C.8
Bush, A.M.9
Moir, T.10
Tanzi, R.E.11
Growdon, J.H.12
Nitsch, R.M.13
-
75
-
-
0028787195
-
Surface phosphorylation by ecto-protein kinase C in brain neurons: A target for Alzheimer's β-amyloid peptides
-
Hogan M. V., Pawlowska Z., Yang H.-A., Kornecki E., and Ehrlich Y. H. (1995) Surface phosphorylation by ecto-protein kinase C in brain neurons: a target for Alzheimer's β-amyloid peptides. J. Neurochem. 65, 2022-2030.
-
(1995)
J. Neurochem.
, vol.65
, pp. 2022-2030
-
-
Hogan, M.V.1
Pawlowska, Z.2
Yang, H.-A.3
Kornecki, E.4
Ehrlich, Y.H.5
-
76
-
-
0031025045
-
1-42 suppresses acetylcholine synthesis
-
1-42 suppresses acetylcholine synthesis. J. Biol. Chem. 272, 2038-2041.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2038-2041
-
-
Hoshi, M.1
Takashima, A.2
Murayama, M.3
Yasutake, K.4
Yoshida, N.5
Ishiguro, K.6
Hoshino, T.7
Imahori, K.8
-
77
-
-
0032568843
-
Modulation of secreted β-amyloid precursor protein and amyloid β-peptide in brain by cholesterol
-
Howland D. S., Trusko S. P., Savage M. J., Reaume A. G., Lang D. M., Hirsch J. D., Maeda N., Siman R., Greenberg B. D., Scott R. W., and Flood D. G. (1998) Modulation of secreted β-amyloid precursor protein and amyloid β-peptide in brain by cholesterol. J. Biol. Chem. 273, 16576-16582.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16576-16582
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
Maeda, N.7
Siman, R.8
Greenberg, B.D.9
Scott, R.W.10
Flood, D.G.11
-
78
-
-
0029742199
-
Correlative memory deficits. Aβ elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., and Cole G. (1996) Correlative memory deficits. Aβ elevation, and amyloid plaques in transgenic mice. Science 274, 99-103.
-
(1996)
Science
, vol.274
, pp. 99-103
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
79
-
-
0027409609
-
Involvement of amyloid precursor protein in memory formation in the rat: An indirect antibody approach
-
Huber G., Martin J. R., Loffler J., and Moreau J. L. (1993) Involvement of amyloid precursor protein in memory formation in the rat: an indirect antibody approach. Brain Res. 603, 348-352.
-
(1993)
Brain Res.
, vol.603
, pp. 348-352
-
-
Huber, G.1
Martin, J.R.2
Loffler, J.3
Moreau, J.L.4
-
80
-
-
0028057224
-
Selective ectodomain phosphorylation and regulated cleavage of β-amyloid precursor protein
-
Hung A. Y. and Selkoe D. J. (1994) Selective ectodomain phosphorylation and regulated cleavage of β-amyloid precursor protein. EMBO J. 13, 534-542.
-
(1994)
EMBO J
, vol.13
, pp. 534-542
-
-
Hung, A.Y.1
Selkoe, D.J.2
-
81
-
-
0027453490
-
Activation of protein kinase C inhibits cellular production of the amyloid β-protein
-
Hung A. Y., Haass C. Nitsch R. M., Qiu W. Q., Citron M., Wurtman R. J., Growdon J. H., and Selkoe D. J. (1993) Activation of protein kinase C inhibits cellular production of the amyloid β-protein. J. Biol. Chem. 268, 22959-22962.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22959-22962
-
-
Hung, A.Y.1
Haass, C.2
Nitsch, R.M.3
Qiu, W.Q.4
Citron, M.5
Wurtman, R.J.6
Growdon, J.H.7
Selkoe, D.J.8
-
82
-
-
0030885417
-
Transbilayer distribution of cholesterol is modified in brain synaptic plasma membranes of knockout mice deficient in the low-density lipoprotein receptor, apolipoprotein E. or both proteins
-
Igbavboa U., Avdulov N. A., Chochina S. V., and Wood W. G. (1997) Transbilayer distribution of cholesterol is modified in brain synaptic plasma membranes of knockout mice deficient in the low-density lipoprotein receptor, apolipoprotein E. or both proteins. J. Neurochem. 69, 1661-1667.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1661-1667
-
-
Igbavboa, U.1
Avdulov, N.A.2
Chochina, S.V.3
Wood, W.G.4
-
83
-
-
0032562615
-
Caveolae, plasma membrane microdomains for α-secretase-mediated processing of the amyloid precursor protein
-
Ikezu T., Trapp B. D., Song K. S., Schlegel A., Lisanti M. P., and Okamoto T. (1998) Caveolae, plasma membrane microdomains for α-secretase-mediated processing of the amyloid precursor protein. J. Biol. Chem. 273, 10485-10495.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10485-10495
-
-
Ikezu, T.1
Trapp, B.D.2
Song, K.S.3
Schlegel, A.4
Lisanti, M.P.5
Okamoto, T.6
-
84
-
-
0031931152
-
Secreted form of β-amyloid precursor protein activates protein kinase C and phospholipase C-γ-1 in cultured embryonic rat neocortical cells
-
Ishiguro M., Ohsawa I., Takamura C., Morimoto T., and Kohsaka S. (1998) Secreted form of β-amyloid precursor protein activates protein kinase C and phospholipase C-γ-1 in cultured embryonic rat neocortical cells. Mol. Brain Res. 53, 24-32.
-
(1998)
Mol. Brain Res.
, vol.53
, pp. 24-32
-
-
Ishiguro, M.1
Ohsawa, I.2
Takamura, C.3
Morimoto, T.4
Kohsaka, S.5
-
85
-
-
0028246846
-
The release of Alzheimer's disease β-amyloid peptide is reduced by phorbol treatment
-
Jacobsen J. S., Spruyt M. A., Brown A. M., Sahasrabubhe S. R., Blume A. J., Vitek M. P., Muenkel H. A., and Sonnenberg-Reines J. (1994) The release of Alzheimer's disease β-amyloid peptide is reduced by phorbol treatment. J. Biol. Chem. 269, 8376-8382.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8376-8382
-
-
Jacobsen, J.S.1
Spruyt, M.A.2
Brown, A.M.3
Sahasrabubhe, S.R.4
Blume, A.J.5
Vitek, M.P.6
Muenkel, H.A.7
Sonnenberg-Reines, J.8
-
86
-
-
0028342424
-
Estrogen regulates metabolism of Alzheimer amyloid β precursor protein
-
Jaffe A. B., Toran-Allerand C. D., Greengard P., and Gandy S. E. (1994) Estrogen regulates metabolism of Alzheimer amyloid β precursor protein. J. Biol. Chem. 269, 13065-13068.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13065-13068
-
-
Jaffe, A.B.1
Toran-Allerand, C.D.2
Greengard, P.3
Gandy, S.E.4
-
87
-
-
0029240533
-
Changes in protein kinases in brain aging and Alzheimer's disease. Implications for drug therapy
-
Jin L. W., and Saitoh T. (1995) Changes in protein kinases in brain aging and Alzheimer's disease. Implications for drug therapy Drugs Aging 6, 136-149.
-
(1995)
Drugs Aging
, vol.6
, pp. 136-149
-
-
Jin, L.W.1
Saitoh, T.2
-
88
-
-
0032577677
-
Regulation of amyloid precursor protein secretion by glutamate receptors in human Ntera 2 neurons (NT2N)
-
Jolly-Tornetta C., Gao Z., Lee V. M.-Y., and Wolf B. A. (1998) Regulation of amyloid precursor protein secretion by glutamate receptors in human Ntera 2 neurons (NT2N). J. Biol. Chem. 273, 14015-14021.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14015-14021
-
-
Jolly-Tornetta, C.1
Gao, Z.2
Lee, V.M.-Y.3
Wolf, B.A.4
-
89
-
-
0030983079
-
Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease
-
Kaltschmidt B., Uherek M., Volk B., and Baeuerle P. A. (1997) Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA 94, 2642-2647.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2642-2647
-
-
Kaltschmidt, B.1
Uherek, M.2
Volk, B.3
Baeuerle, P.A.4
-
90
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell surface receptor
-
Kang J., Lemaire H. G., Unterbeck A., Salbaum J. M., Master C. L., Grzeschik K. H., Multhaup G., Beyreuther K., and Muller-Hill B. (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell surface receptor. Nature 325, 733-736.
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Master, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
91
-
-
0029996479
-
β-Amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices
-
Kar S., Seto D., Gaudreau P., and Quirion R. (1996) β-Amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices. J. Neurosci. 16, 1034-1040.
-
(1996)
J. Neurosci.
, vol.16
, pp. 1034-1040
-
-
Kar, S.1
Seto, D.2
Gaudreau, P.3
Quirion, R.4
-
92
-
-
0029900084
-
Amyloid β-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons
-
Kelly J. F., Furukawa K., Barger S. W., Rengen M. R., Mark R. J., Blanc E. M., Roth G. S., and Mattson M. P. (1996) Amyloid β-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons. Proc. Natl. Acad. Sci. USA 93, 6753-6758.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6753-6758
-
-
Kelly, J.F.1
Furukawa, K.2
Barger, S.W.3
Rengen, M.R.4
Mark, R.J.5
Blanc, E.M.6
Roth, G.S.7
Mattson, M.P.8
-
93
-
-
0030880424
-
Enhanced release of secreted form of Alzheimer's amyloid precursor protein from PC12 cells by nicotine
-
Kim S.-H., Kim Y.-K., Jeong S.-J., Haass C. Kim Y.-H., and Suh Y.-H. (1997) Enhanced release of secreted form of Alzheimer's amyloid precursor protein from PC12 cells by nicotine. Mol. Pharmacol. 52, 430-436.
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 430-436
-
-
Kim, S.-H.1
Kim, Y.-K.2
Jeong, S.-J.3
Haass, C.4
Kim, Y.-H.5
Suh, Y.-H.6
-
94
-
-
0029056812
-
Arachidonate metabolites affect the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein
-
Kinouchi T., Ono Y., Sormachi H., Ishiura S., and Suzuki K. (1995a) Arachidonate metabolites affect the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein. Biochem. Biophys. Res. Commun. 209, 841-849.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.209
, pp. 841-849
-
-
Kinouchi, T.1
Ono, Y.2
Sormachi, H.3
Ishiura, S.4
Suzuki, K.5
-
95
-
-
0028965767
-
Conventional protein kinase C (PKC)-α and novel PKC∈ but not -δ. Increase the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein from PKC cDNA transfected 3Y1 fibroblasts
-
Kinouchi T., Sorimachi H., Maruyama K., Mizuno K., Ohno S., Ishiura S., and Suzuki K. (1995b) Conventional protein kinase C (PKC)-α and novel PKC∈ but not -δ. increase the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein from PKC cDNA transfected 3Y1 fibroblasts. FEBS Lett. 364, 203-206.
-
(1995)
FEBS Lett.
, vol.364
, pp. 203-206
-
-
Kinouchi, T.1
Sorimachi, H.2
Maruyama, K.3
Mizuno, K.4
Ohno, S.5
Ishiura, S.6
Suzuki, K.7
-
96
-
-
0030902317
-
Glutamate-stimulated secretion of amyloid precursor protein from cortical rat brain slices
-
Kirazov L., Loffler T., Schliebs R., and Bigl V. (1997) Glutamate-stimulated secretion of amyloid precursor protein from cortical rat brain slices. Neurochem. Int. 30, 557-563.
-
(1997)
Neurochem. Int.
, vol.30
, pp. 557-563
-
-
Kirazov, L.1
Loffler, T.2
Schliebs, R.3
Bigl, V.4
-
97
-
-
0029905596
-
The carboxyl termini of β-amyloid peptides 1-40 and 1-42 are generated by distinct γ-secretase activities
-
Klafki H. W., Abramowski D., Swoboda R., Paganetti P. A., and Staufenbiel M. (1996) The carboxyl termini of β-amyloid peptides 1-40 and 1-42 are generated by distinct γ-secretase activities. J. Biol. Chem. 271, 28655-28659.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 28655-28659
-
-
Klafki, H.W.1
Abramowski, D.2
Swoboda, R.3
Paganetti, P.A.4
Staufenbiel, M.5
-
98
-
-
0031944765
-
2+ increase in rat cultured hippocampal neurones
-
2+ increase in rat cultured hippocampal neurones. Br. J. Pharmacol. 123, 1483-1489.
-
(1998)
Br. J. Pharmacol.
, vol.123
, pp. 1483-1489
-
-
Koizumi, S.1
Ishiguro, M.2
Ohsawa, I.3
Morimoto, T.4
Takamura, T.5
Inoue, K.6
Kohsaka, S.7
-
99
-
-
0030452221
-
Biological therapies for Alzheimer's disease: Focus on trophic factors
-
Koliatsos V. E. (1996) Biological therapies for Alzheimer's disease: focus on trophic factors. Crit. Rev: Neurobiol. 10, 205-238.
-
(1996)
Crit. Rev: Neurobiol.
, vol.10
, pp. 205-238
-
-
Koliatsos, V.E.1
-
100
-
-
0030920771
-
A kinase to remember: Dual roles for MAP kinase in long-term memory
-
Kornhauser J. M. and Greenberg M. E. (1997) A kinase to remember: dual roles for MAP kinase in long-term memory. Neuron 18, 839-842.
-
(1997)
Neuron
, vol.18
, pp. 839-842
-
-
Kornhauser, J.M.1
Greenberg, M.E.2
-
101
-
-
0026539331
-
Alzheimer's disease: A cell biological perspective
-
Kosik K. S. (1993) Alzheimer's disease: a cell biological perspective. Science 256, 780-783.
-
(1993)
Science
, vol.256
, pp. 780-783
-
-
Kosik, K.S.1
-
102
-
-
13344282063
-
Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells
-
Kovacs D. M., Fausett H. J., Page K. J., Kim T.-W., Moir R. D., Merriam D. E., Hollister R. D., Hallmark O. G., Mancini R., Felsenstein K. M., Hyman B. T., Tanzi R. E., and Wasco W. (1996) Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nat. Med. 2, 224-229.
-
(1996)
Nat. Med.
, vol.2
, pp. 224-229
-
-
Kovacs, D.M.1
Fausett, H.J.2
Page, K.J.3
Kim, T.-W.4
Moir, R.D.5
Merriam, D.E.6
Hollister, R.D.7
Hallmark, O.G.8
Mancini, R.9
Felsenstein, K.M.10
Hyman, B.T.11
Tanzi, R.E.12
Wasco, W.13
-
103
-
-
0027484116
-
The Alzheimer β-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells
-
Kuentzel S. L., Ali S. M., Altman R. A., Greenberg B. D., and Raub T. J. (1993) The Alzheimer β-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells. Biochem. J. 295, 367-378.
-
(1993)
Biochem. J.
, vol.295
, pp. 367-378
-
-
Kuentzel, S.L.1
Ali, S.M.2
Altman, R.A.3
Greenberg, B.D.4
Raub, T.J.5
-
104
-
-
0029671451
-
Water-soluble Aβ (N40, N42) oligomers in normal and Alzheimer disease brains
-
Kuo Y.-M., Emmerling M. R., Vigo-Pelfrey C. Kasunic T. C., Kirkpatrick J. B., Murdoch G. H., Ball M. J., and Roher A. E. (1996) Water-soluble Aβ (N40, N42) oligomers in normal and Alzheimer disease brains. J. Biol. Chem. 271, 4077-4081.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4077-4081
-
-
Kuo, Y.-M.1
Emmerling, M.R.2
Vigo-Pelfrey, C.3
Kasunic, T.C.4
Kirkpatrick, J.B.5
Murdoch, G.H.6
Ball, M.J.7
Roher, A.E.8
-
105
-
-
0029114162
-
Promoter activity of the gene encoding the β-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid, and interleukin-1
-
Lahiri D. K. and Nall C. (1995) Promoter activity of the gene encoding the β-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid, and interleukin-1. Mol. Brain Res. 32, 233-240.
-
(1995)
Mol. Brain Res.
, vol.32
, pp. 233-240
-
-
Lahiri, D.K.1
Nall, C.2
-
106
-
-
11544279355
-
1-42 are potent central nervous system neurotoxins
-
1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. USA 95, 6448-6453.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
107
-
-
0029609021
-
Increased production of 4 kDa amyloid β peptide in serum deprived human primary neurons cultures: Possible involvement of apoptosis
-
LeBlanc A. C. (1995) Increased production of 4 kDa amyloid β peptide in serum deprived human primary neurons cultures: possible involvement of apoptosis. J. Neurosci. 15, 7837-7846.
-
(1995)
J. Neurosci.
, vol.15
, pp. 7837-7846
-
-
LeBlanc, A.C.1
-
108
-
-
0026072869
-
Differential APP gene expression in neonatal rat cerebral cortex, meninges and primary astroglial, neuronal and microglial cell
-
LeBlanc A. C., Chen H., Autilio-Gambetti L., and Gambetti P. (1991) Differential APP gene expression in neonatal rat cerebral cortex, meninges and primary astroglial, neuronal and microglial cell. FEBS Lett. 292, 171-178.
-
(1991)
FEBS Lett.
, vol.292
, pp. 171-178
-
-
LeBlanc, A.C.1
Chen, H.2
Autilio-Gambetti, L.3
Gambetti, P.4
-
109
-
-
0032523039
-
Protein kinase C activation increases release of secreted amyloid precursor protein without decreasing Aβ production in human primary neuron cultures
-
LeBlanc A. C., Koutroumanis M., and Goodyer C. G. (1998) Protein kinase C activation increases release of secreted amyloid precursor protein without decreasing Aβ production in human primary neuron cultures. J. Neurosci. 15, 2907-2913.
-
(1998)
J. Neurosci.
, vol.15
, pp. 2907-2913
-
-
LeBlanc, A.C.1
Koutroumanis, M.2
Goodyer, C.G.3
-
110
-
-
0030944118
-
Metabotropic glutamate receptors increase amyloid precursor protein processing in astrocytes: Inhibition by cyclic AMP
-
Lee R. K. K. and Wurtman R. J. (1997) Metabotropic glutamate receptors increase amyloid precursor protein processing in astrocytes: inhibition by cyclic AMP. J. Neurochem. 68, 1830-1835.
-
(1997)
J. Neurochem.
, vol.68
, pp. 1830-1835
-
-
Lee, R.K.K.1
Wurtman, R.J.2
-
111
-
-
0029147583
-
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors
-
Lee R. K. K., Wurtman R. J., Cox A. J., and Nitsch R. M. (1995) Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. Proc. Natl. Acad. Sci. USA 92, 8083-8087.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8083-8087
-
-
Lee, R.K.K.1
Wurtman, R.J.2
Cox, A.J.3
Nitsch, R.M.4
-
112
-
-
0029665941
-
Activation of phospholipase A, by amyloid β-peptides in vitro
-
Lehtonen J. Y. A., Holopainen J. M., and Kinnunen P. K. J. (1996) Activation of phospholipase A, by amyloid β-peptides in vitro. Biochemistry 35, 9407-9414.
-
(1996)
Biochemistry
, vol.35
, pp. 9407-9414
-
-
Lehtonen, J.Y.A.1
Holopainen, J.M.2
Kinnunen, P.K.J.3
-
113
-
-
16044365171
-
The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology
-
Lemere C. A., Lopera F., Kosik K. S., Lendon C. L., Ossa J., Saido T. C., Yamaguchi H., Ruiz A., Martinez A., Madrigal L., Hincapie L., Carlos Arango L. J., Anthony D. C., Koo E. H., Goate A. M., Selkoe D. J., and Carlos Arango V. J. (1996) The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology. Nat. Med. 2, 1146-1150.
-
(1996)
Nat. Med.
, vol.2
, pp. 1146-1150
-
-
Lemere, C.A.1
Lopera, F.2
Kosik, K.S.3
Lendon, C.L.4
Ossa, J.5
Saido, T.C.6
Yamaguchi, H.7
Ruiz, A.8
Martinez, A.9
Madrigal, L.10
Hincapie, L.11
Carlos Arango, L.J.12
Anthony, D.C.13
Koo, E.H.14
Goate, A.M.15
Selkoe, D.J.16
Carlos Arango, V.J.17
-
114
-
-
0028968949
-
Tyrosine kinase inhibition: An approach to drug development
-
Levitzki A. and Gazit A. (1995) Tyrosine kinase inhibition: an approach to drug development. Science 267, 1782-1788.
-
(1995)
Science
, vol.267
, pp. 1782-1788
-
-
Levitzki, A.1
Gazit, A.2
-
115
-
-
0030761059
-
Alzheimer presenilins in the nuclear membrane interphase kinetochores and centrosomes suggest a role in chromosome segregation
-
Li J., Xu M., Zhou H., Ma J., and Potter H. (1997) Alzheimer presenilins in the nuclear membrane interphase kinetochores and centrosomes suggest a role in chromosome segregation. Cell 90, 917-927.
-
(1997)
Cell
, vol.90
, pp. 917-927
-
-
Li, J.1
Xu, M.2
Zhou, H.3
Ma, J.4
Potter, H.5
-
116
-
-
0028319060
-
-
Lisanti M. P., Scherer P. E . Vidugiriene J., Tang Z.-L., Hermanoski-Vosatka A., Tu Y.-H., Cook R. F., and Sargiacomo M. (1994) J. Cell. Biol. 126, 111-126.
-
(1994)
J. Cell. Biol.
, vol.126
, pp. 111-126
-
-
Lisanti, M.P.1
Scherer, P.E.2
Vidugiriene, J.3
Tang, Z.-L.4
Hermanoski-Vosatka, A.5
Tu, Y.-H.6
Cook, R.F.7
Sargiacomo, M.8
-
117
-
-
0028978360
-
Physiological levels of β-amyloid increase tyrosine phosphorylation and cytosolic calcium
-
Luo Y., Hirashima N., Li Y., Alkon D., Sunderland T., Etcheberrigaray R., and Wolozin B. (1995) Physiological levels of β-amyloid increase tyrosine phosphorylation and cytosolic calcium. Brain Res. 681, 65-74.
-
(1995)
Brain Res.
, vol.681
, pp. 65-74
-
-
Luo, Y.1
Hirashima, N.2
Li, Y.3
Alkon, D.4
Sunderland, T.5
Etcheberrigaray, R.6
Wolozin, B.7
-
118
-
-
0029837577
-
Physiological levels of β-amyloid activate phosphatidylinositol 3-kinase with the involvement of tyrosine phosphorylation
-
Luo Y., Sunderland T., and Wolozin B. (1996) Physiological levels of β-amyloid activate phosphatidylinositol 3-kinase with the involvement of tyrosine phosphorylation. J. Neurochem. 67, 978-987.
-
(1996)
J. Neurochem.
, vol.67
, pp. 978-987
-
-
Luo, Y.1
Sunderland, T.2
Wolozin, B.3
-
119
-
-
0028173205
-
1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments
-
1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments. Nature 372, 92-94.
-
(1994)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer, H.B.3
Das, S.4
Potter, H.5
-
120
-
-
0029805807
-
Protein kinase A phosphorylation of the proteasome: A contribution to the α-secretase pathway in human cells
-
Marambaud P., Wilk S., and Checler F. (1996) Protein kinase A phosphorylation of the proteasome: a contribution to the α-secretase pathway in human cells. J. Neurochem. 67, 2616-2619.
-
(1996)
J. Neurochem.
, vol.67
, pp. 2616-2619
-
-
Marambaud, P.1
Wilk, S.2
Checler, F.3
-
121
-
-
0031022252
-
Proteasome contributes to the α-secretase pathway of amyloid precursor protein in human cells
-
Marambaud P., Chevallier N., Barelli H., Wilk S., and Checler F. (1997a) Proteasome contributes to the α-secretase pathway of amyloid precursor protein in human cells. J. Neurochem. 68, 698-703.
-
(1997)
J. Neurochem.
, vol.68
, pp. 698-703
-
-
Marambaud, P.1
Chevallier, N.2
Barelli, H.3
Wilk, S.4
Checler, F.5
-
122
-
-
0030667097
-
Constitutive and protein kinase C-regulated secretory cleavage of Alzheimer's β-amyloid precursor protein: Different control of early and late events by the proteasome
-
Marambaud P., Lopez-Perez E., Wilk S., and Checler F. (1997b) Constitutive and protein kinase C-regulated secretory cleavage of Alzheimer's β-amyloid precursor protein: different control of early and late events by the proteasome. J. Neurochem. 69, 2500-2505.
-
(1997)
J. Neurochem.
, vol.69
, pp. 2500-2505
-
-
Marambaud, P.1
Lopez-Perez, E.2
Wilk, S.3
Checler, F.4
-
123
-
-
0029813177
-
Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and Alzheimer's disease
-
Masliah E., Sisk A., Mallory M., Mucke L., Schenk D., and Games D. (1996) Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and Alzheimer's disease. J. Neurosci. 16, 5795-5811.
-
(1996)
J. Neurosci.
, vol.16
, pp. 5795-5811
-
-
Masliah, E.1
Sisk, A.2
Mallory, M.3
Mucke, L.4
Schenk, D.5
Games, D.6
-
124
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer's disease and Down's syndrome
-
Masters C., Simms G., Weinman N., Multhaup G., McDonald B., and Beyreuther K. (1985) Amyloid plaque core protein in Alzheimer's disease and Down's syndrome. Proc. Natl. Acad. Sci. USA 82, 4245-4249.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 4245-4249
-
-
Masters, C.1
Simms, G.2
Weinman, N.3
Multhaup, G.4
McDonald, B.5
Beyreuther, K.6
-
125
-
-
0028175579
-
Secreted forms of β-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons
-
Mattson M. P. (1994) Secreted forms of β-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons. J. Neurobiol. 25, 439-450.
-
(1994)
J. Neurobiol.
, vol.25
, pp. 439-450
-
-
Mattson, M.P.1
-
126
-
-
0030779677
-
Cellular actions of β-amyloid precursor protein and its soluble and fibrillogenic derivatives
-
Mattson M. P. (1997) Cellular actions of β-amyloid precursor protein and its soluble and fibrillogenic derivatives. Physiol. Rev. 77, 1081-1132.
-
(1997)
Physiol. Rev.
, vol.77
, pp. 1081-1132
-
-
Mattson, M.P.1
-
127
-
-
0027478347
-
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein
-
Mattson M. P., Cheng B., Culwell A. R., Esch F. S., Lieberburg I., and Rydel R. E. (1993) Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein. Neuron 10, 243-254.
-
(1993)
Neuron
, vol.10
, pp. 243-254
-
-
Mattson, M.P.1
Cheng, B.2
Culwell, A.R.3
Esch, F.S.4
Lieberburg, I.5
Rydel, R.E.6
-
128
-
-
0031054724
-
Cellular signaling roles of TGFβ, TNFα and βAPP in brain injury responses and Alzheimer's disease
-
Mattson M. P., Barger S. W., Furukawa K., Bruce A. J., Wyss-Coray T., Mark R. J., and Mucke L. (1997) Cellular signaling roles of TGFβ, TNFα and βAPP in brain injury responses and Alzheimer's disease. Brain Res. Rev. 23, 47-61.
-
(1997)
Brain Res. Rev.
, vol.23
, pp. 47-61
-
-
Mattson, M.P.1
Barger, S.W.2
Furukawa, K.3
Bruce, A.J.4
Wyss-Coray, T.5
Mark, R.J.6
Mucke, L.7
-
129
-
-
0029917887
-
Anti-inflammatory drugs in the fight against Alzheimer's disease
-
McGeer P. L. and McGeer E. G. (1996) Anti-inflammatory drugs in the fight against Alzheimer's disease. Ann. NY Acad. Sci. 777, 213-220.
-
(1996)
Ann. NY Acad. Sci.
, vol.777
, pp. 213-220
-
-
McGeer, P.L.1
McGeer, E.G.2
-
130
-
-
0029839831
-
Phorbol esters but not the cholinergic agonist oxotremorine-M and carbachol increase release of the amyloid precursor protein in cultured rat cortical neurons
-
Mills J. and Reiner P. B. (1996) Phorbol esters but not the cholinergic agonist oxotremorine-M and carbachol increase release of the amyloid precursor protein in cultured rat cortical neurons. J. Neurosci. 67, 1511-1518.
-
(1996)
J. Neurosci.
, vol.67
, pp. 1511-1518
-
-
Mills, J.1
Reiner, P.B.2
-
131
-
-
0031453010
-
Regulation of amyloid precursor protein catabolism involves the mitogen-activated protein kinase signal transduction pathway
-
Mills J., Charest D. L., Lam F., Beyreuther K., Ida N., Pelech S. L., and Reiner P. B. (1997) Regulation of amyloid precursor protein catabolism involves the mitogen-activated protein kinase signal transduction pathway. J. Neurosci. 17, 9415-9422.
-
(1997)
J. Neurosci.
, vol.17
, pp. 9415-9422
-
-
Mills, J.1
Charest, D.L.2
Lam, F.3
Beyreuther, K.4
Ida, N.5
Pelech, S.L.6
Reiner, P.B.7
-
132
-
-
0025180950
-
Modulation of metarhodopson formation by cholesterol-induced ordering of bilayer lipids
-
Mitchell D. C., Straume M., Miller J. L., and Litman B. J. (1990) Modulation of metarhodopson formation by cholesterol-induced ordering of bilayer lipids. Biochemistry 29, 9143-9149.
-
(1990)
Biochemistry
, vol.29
, pp. 9143-9149
-
-
Mitchell, D.C.1
Straume, M.2
Miller, J.L.3
Litman, B.J.4
-
133
-
-
0001585073
-
Nerve growth factor increases mRNA levels for the prion protein and the β-amyloid protein precursor in developing hamster brain
-
Mobley W. C., Neve R. L., Prusiner S. B., and McKinley M. P. (1988) Nerve growth factor increases mRNA levels for the prion protein and the β-amyloid protein precursor in developing hamster brain. Proc. Natl. Acad. Sci. USA 85, 9811-9815.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 9811-9815
-
-
Mobley, W.C.1
Neve, R.L.2
Prusiner, S.B.3
McKinley, M.P.4
-
134
-
-
0029917041
-
Expression in brain of amyloid precursor protein mutated in the α-secretase site causes disturbed behaviour, neuronal degeneration and premature death in transgenic mice
-
Moechars D., Lorent K., De Strooper B., Dewachter I., and Van Leuven F. (1996) Expression in brain of amyloid precursor protein mutated in the α-secretase site causes disturbed behaviour, neuronal degeneration and premature death in transgenic mice. EMBO J. 15, 1265-1274.
-
(1996)
EMBO J
, vol.15
, pp. 1265-1274
-
-
Moechars, D.1
Lorent, K.2
De Strooper, B.3
Dewachter, I.4
Van Leuven, F.5
-
135
-
-
0028085084
-
Neurotransmitter replacement therapy in Alzheimer's disease
-
Mohr E., Mendis T., Rusk I. N., and Grimes J. D. (1994) Neurotransmitter replacement therapy in Alzheimer's disease. j. Psychiatr. Neurosci. 19, 17-23.
-
(1994)
J. Psychiatr. Neurosci.
, vol.19
, pp. 17-23
-
-
Mohr, E.1
Mendis, T.2
Rusk, I.N.3
Grimes, J.D.4
-
136
-
-
0032570571
-
Relative increase in Alzheimer's disease of soluble forms of cerebral Aβ amyloid protein precursor containing the Kunitz protease inhibitory domain
-
Moir R. D., Lynch T., Bush A. I., Whyte S., Henry A., Portbury S., Multhaup G., Small D. H., Tanzi R. E., Beyreuther K., and Masters C. L. (1998) Relative increase in Alzheimer's disease of soluble forms of cerebral Aβ amyloid protein precursor containing the Kunitz protease inhibitory domain. J. Biol. Chem. 273, 5013-5019.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5013-5019
-
-
Moir, R.D.1
Lynch, T.2
Bush, A.I.3
Whyte, S.4
Henry, A.5
Portbury, S.6
Multhaup, G.7
Small, D.H.8
Tanzi, R.E.9
Beyreuther, K.10
Masters, C.L.11
-
138
-
-
0030698871
-
Life and death of neurons in the aging brain
-
Morrison J. H. and Hof P. R. (1997) Life and death of neurons in the aging brain. Science 278, 412-419.
-
(1997)
Science
, vol.278
, pp. 412-419
-
-
Morrison, J.H.1
Hof, P.R.2
-
139
-
-
0026907151
-
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid
-
Mullan M., Crawford F., Axelman K., Houlden H., Lilius L., Winblad B., and Lannfelt L. (1992) A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid. Nat. Genet. 1, 345-347.
-
(1992)
Nat. Genet.
, vol.1
, pp. 345-347
-
-
Mullan, M.1
Crawford, F.2
Axelman, K.3
Houlden, H.4
Lilius, L.5
Winblad, B.6
Lannfelt, L.7
-
140
-
-
0343811715
-
1 receptor agonists increase the secretion of the amyloid precursor protein ectodomain
-
1 receptor agonists increase the secretion of the amyloid precursor protein ectodomain. Life Sci. 60, 985-991.
-
(1997)
Life Sci.
, vol.60
, pp. 985-991
-
-
Müller, D.M.1
Mendla, K.2
Farber, S.A.3
Nitsch, R.M.4
-
141
-
-
0028018919
-
Behavioural and anatomical deficits in mice homozygous for a modified β-amyloid precursor protein gene
-
Müller U., Cristina N., Li Z.-W., Wolfer D. P., Lipp H.-P., Rülicke T., Brandner S., Aguzzi A., and Weissmann C. (1994) Behavioural and anatomical deficits in mice homozygous for a modified β-amyloid precursor protein gene. Cell 79, 755-765.
-
(1994)
Cell
, vol.79
, pp. 755-765
-
-
Müller, U.1
Cristina, N.2
Li, Z.-W.3
Wolfer, D.P.4
Lipp, H.-P.5
Rülicke, T.6
Brandner, S.7
Aguzzi, A.8
Weissmann, C.9
-
142
-
-
0343554069
-
Advanced glycation endproducts in ageing and Alzheimer's disease
-
Münch G., Thome J., Foley P., Schinzel R., and Riederer P. (1997) Advanced glycation endproducts in ageing and Alzheimer's disease. Brain Res. Rev. 23, 134-143.
-
(1997)
Brain Res. Rev.
, vol.23
, pp. 134-143
-
-
Münch, G.1
Thome, J.2
Foley, P.3
Schinzel, R.4
Riederer, P.5
-
143
-
-
0030978998
-
Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein
-
Nalbantoglu J., Tirado-Santiago G., Lahsaïni A., Poirier J., Goncalves O., Verge G., Momoli F., Welner S. A., Massicotte G., Julien J.-P., and Shapiro M. L. (1997) Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature 387, 500-505.
-
(1997)
Nature
, vol.387
, pp. 500-505
-
-
Nalbantoglu, J.1
Tirado-Santiago, G.2
Lahsaïni, A.3
Poirier, J.4
Goncalves, O.5
Verge, G.6
Momoli, F.7
Welner, S.A.8
Massicotte, G.9
Julien, J.-P.10
Shapiro, M.L.11
-
144
-
-
0028106152
-
Relative abundance of Alzheimer Aβ amyloid peptide variants in Alzheimer's disease and normal aging
-
Naslund J., Schiernhorn A., Hellmann U., Lannfelt L., Roses A. D., Tuernberg L. O., Silberring J., Gandy S. E., Winblad B., Greengard P., Nordstedt D., and Terenius L. (1994) Relative abundance of Alzheimer Aβ amyloid peptide variants in Alzheimer's disease and normal aging. Proc. Natl. Acad. Sci. USA 91, 8378-8382.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8378-8382
-
-
Naslund, J.1
Schiernhorn, A.2
Hellmann, U.3
Lannfelt, L.4
Roses, A.D.5
Tuernberg, L.O.6
Silberring, J.7
Gandy, S.E.8
Winblad, B.9
Greengard, P.10
Nordstedt, D.11
Terenius, L.12
-
145
-
-
0028811653
-
Protein kinase C: Structure, function, and regulation
-
Newton A. C. (1995) Protein kinase C: structure, function, and regulation. J. Biol. Chem. 270, 28495-28498.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28495-28498
-
-
Newton, A.C.1
-
146
-
-
0028201847
-
Role of neurotransmission in the regulation of amyloid β-protein precursor processing
-
Nitsch R. M. and Growdon J. H. (1994) Role of neurotransmission in the regulation of amyloid β-protein precursor processing. Biochem. Pharmacol. 47, 1275-1284.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 1275-1284
-
-
Nitsch, R.M.1
Growdon, J.H.2
-
147
-
-
0026476297
-
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
-
Nitsch R. M., Slack B. E., Wurtman R. J., and Growdon J. H. (1992) Release of Alzheimer amyloid precursor derivatives stimulated by activation of
-
(1992)
Science
, vol.258
, pp. 304-307
-
-
Nitsch, R.M.1
Slack, B.E.2
Wurtman, R.J.3
Growdon, J.H.4
-
148
-
-
0027209083
-
Release of amyloid β-protein precursor derivatives by electrical depolarization of rat hippocampal slices
-
Nitsch R. M., Farber S. A., Growdon J. H., and Wurtman R. J. (1993) Release of amyloid β-protein precursor derivatives by electrical depolarization of rat hippocampal slices. Proc. Natl. Acad. Sci. USA 90, 5191-5193.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5191-5193
-
-
Nitsch, R.M.1
Farber, S.A.2
Growdon, J.H.3
Wurtman, R.J.4
-
149
-
-
0027421610
-
Receptor-coupled amyloid precursor protein processing
-
Nitsch R. M., Slack B. E., Farber S. A., Borghesani P. R., Schulz J. G., Kim C., Felder C. C., Growdon J. H., and Wurtman R. J. (1994) Receptor-coupled amyloid precursor protein processing. Ann. NY Acad Sci. 881, 122-127.
-
(1994)
Ann. NY Acad Sci.
, vol.881
, pp. 122-127
-
-
Nitsch, R.M.1
Slack, B.E.2
Farber, S.A.3
Borghesani, P.R.4
Schulz, J.G.5
Kim, C.6
Felder, C.C.7
Growdon, J.H.8
Wurtman, R.J.9
-
150
-
-
0030028598
-
Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion
-
Nitsch R. M., Deng M., Growdon J. H., and Wurtman R. J. (1996) Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion. J. Biol. Chem. 271, 4188-4194.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4188-4194
-
-
Nitsch, R.M.1
Deng, M.2
Growdon, J.H.3
Wurtman, R.J.4
-
151
-
-
0030790252
-
Metabotropic glutamate receptor subtype mGluR1α stimulates the secretion of the amyloid βprotein precursor ectodomain
-
Nitsch R. M., Deng A., Wurtman R. J., and Growdon J. H. (1997) Metabotropic glutamate receptor subtype mGluR1α stimulates the secretion of the amyloid βprotein precursor ectodomain. J. Neurochem. 69, 704-712.
-
(1997)
J. Neurochem.
, vol.69
, pp. 704-712
-
-
Nitsch, R.M.1
Deng, A.2
Wurtman, R.J.3
Growdon, J.H.4
-
152
-
-
0031898094
-
Vasopressin and bradykinin regulate secretory processing of the amyloid protein precursor of Alzheimer's disease
-
Nitsch R. M., Kim C., and Growdon J. H. (1998) Vasopressin and bradykinin regulate secretory processing of the amyloid protein precursor of Alzheimer's disease. Neurochem. Res. 23, 807-814.
-
(1998)
Neurochem. Res.
, vol.23
, pp. 807-814
-
-
Nitsch, R.M.1
Kim, C.2
Growdon, J.H.3
-
153
-
-
0029973611
-
Inflammatory mechanisms and anti-inflammatory therapy in Alzheimer's disease
-
O'Banion M. K. and Finch C. E. (1996) Inflammatory mechanisms and anti-inflammatory therapy in Alzheimer's disease. Neurobiol. Aging 17, 669-671.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 669-671
-
-
O'Banion, M.K.1
Finch, C.E.2
-
154
-
-
0025264201
-
The Alzheimer amyloid precursor protein. Identification of a stable intermediate in the biosynthetic/degradative pathway
-
Oltersdorf T., Ward P. J., Henriksson R., Beattie E. C., Neve R., Lieberburg I., and Frizt L. C. (1990) The Alzheimer amyloid precursor protein. Identification of a stable intermediate in the biosynthetic/degradative pathway. J. Biol. Chem. 265, 4492-4497.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 4492-4497
-
-
Oltersdorf, T.1
Ward, P.J.2
Henriksson, R.3
Beattie, E.C.4
Neve, R.5
Lieberburg, I.6
Frizt, L.C.7
-
155
-
-
0029910609
-
Amyloid precursor protein truncated at any of the α-secretase sites is not cleaved to β-amyloid
-
Paganetti P. A., Lis M., Klafki H.-W., and Staufenbiel M. (1996) Amyloid precursor protein truncated at any of the α-secretase sites is not cleaved to β-amyloid. J. Neurosci. Res. 46, 283-293.
-
(1996)
J. Neurosci. Res.
, vol.46
, pp. 283-293
-
-
Paganetti, P.A.1
Lis, M.2
Klafki, H.-W.3
Staufenbiel, M.4
-
156
-
-
0842297602
-
The β-amyloid protein precursor of Alzheimer's disease has soluble derivatives found in human brain and cerebrospinal fluid
-
Palmert M. R., Podlisny B. M., Witker D. S., Oltersdorf T., Younkin L. H., Selkoe D. J., and Younkin S. G. (1989) The β-amyloid protein precursor of Alzheimer's disease has soluble derivatives found in human brain and cerebrospinal fluid. Proc. Natl. Acad Sci. USA 86, 6338-6342.
-
(1989)
Proc. Natl. Acad Sci. USA
, vol.86
, pp. 6338-6342
-
-
Palmert, M.R.1
Podlisny, B.M.2
Witker, D.S.3
Oltersdorf, T.4
Younkin, L.H.5
Selkoe, D.J.6
Younkin, S.G.7
-
157
-
-
0026459809
-
Alzheimer's disease and control brain contain soluble derivatives of the amyloid protein precursor that end within the β amyloid protein region
-
Pasternack J. M., Palmert M. R., Usiak M., Wang R., Zurcher-Neely H., Gonzalez-De Whitt P. A., Fairbanks M. B., Cheung T., Blades D., Heinrikson R. L., Greenberg B. D., Cotter R. J., and Younkin S. G. (1992) Alzheimer's disease and control brain contain soluble derivatives of the amyloid protein precursor that end within the β amyloid protein region. Biochemistry 31, 10936-10940.
-
(1992)
Biochemistry
, vol.31
, pp. 10936-10940
-
-
Pasternack, J.M.1
Palmert, M.R.2
Usiak, M.3
Wang, R.4
Zurcher-Neely, H.5
Gonzalez-De Whitt, P.A.6
Fairbanks, M.B.7
Cheung, T.8
Blades, D.9
Heinrikson, R.L.10
Greenberg, B.D.11
Cotter, R.J.12
Younkin, S.G.13
-
158
-
-
0029795254
-
Amyloid β-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain
-
Pedersen W. A., Kloczewiak M. A., and Blusztajn J. K. (1996) Amyloid β-protein reduces acetylcholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain. Proc. Natl. Acad. Sci. USA 93, 8068-8071.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8068-8071
-
-
Pedersen, W.A.1
Kloczewiak, M.A.2
Blusztajn, J.K.3
-
159
-
-
0343109679
-
Cell cycle control in progress
-
(Meijer L., Guidet S., Lim H. Y., and Tung H. Y. L., eds), Plenum Press, New York
-
Pelech S. L. and Charest D. L. (1996) Cell cycle control in progress, in Cell Cycle Research (Meijer L., Guidet S., Lim H. Y., and Tung H. Y. L., eds), pp. 33-52. Plenum Press, New York.
-
(1996)
Cell Cycle Research
, pp. 33-52
-
-
Pelech, S.L.1
Charest, D.L.2
-
160
-
-
0030820822
-
Late compartments of amyloid precursor protein transport in SY5Y cells are involved in β-amyloid secretion
-
Peraus G. C., Masters C. L., and Beyreuther K. (1997) Late compartments of amyloid precursor protein transport in SY5Y cells are involved in β-amyloid secretion. J. Neurosci. 17, 7714-7724.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7714-7724
-
-
Peraus, G.C.1
Masters, C.L.2
Beyreuther, K.3
-
161
-
-
0030472049
-
Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism
-
Petryniak M. A., Wurtman R. J., and Slack B. E. (1996) Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism. Biochem. J. 320, 957-963.
-
(1996)
Biochem. J.
, vol.320
, pp. 957-963
-
-
Petryniak, M.A.1
Wurtman, R.J.2
Slack, B.E.3
-
162
-
-
0028885682
-
Amino-terminal deletions enhance aggregation of β-amyloid peptides in vitro
-
Pike C. J., Overman M. J., and Cotman C. W. (1995) Amino-terminal deletions enhance aggregation of β-amyloid peptides in vitro. J. Biol. Chem. 270, 23895-23898.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23895-23898
-
-
Pike, C.J.1
Overman, M.J.2
Cotman, C.W.3
-
163
-
-
0028172930
-
Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease
-
Poirier J. (1994) Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease. Trends Neurosci. 17, 525-530.
-
(1994)
Trends Neurosci.
, vol.17
, pp. 525-530
-
-
Poirier, J.1
-
164
-
-
0029618124
-
Apolipoprotein E. synaptic plasticity and Alzheimer's disease
-
Poirier J., Minnich A., and Davignon J. (1995) Apolipoprotein E. synaptic plasticity and Alzheimer's disease. Ann. Med. 27, 663-670.
-
(1995)
Ann. Med.
, vol.27
, pp. 663-670
-
-
Poirier, J.1
Minnich, A.2
Davignon, J.3
-
165
-
-
0028204224
-
Calcium ionophore increases amyloid β peptide production by cultured cells
-
Querfurth H. W. and Selkoe D. J. (1994) Calcium ionophore increases amyloid β peptide production by cultured cells. Biochemistry 33, 4550-4561.
-
(1994)
Biochemistry
, vol.33
, pp. 4550-4561
-
-
Querfurth, H.W.1
Selkoe, D.J.2
-
166
-
-
0030987603
-
Caffeine stimulates amyloid β-peptide release from β-amyloid precursor protein-transfected HEK293 cells
-
Querfurth H. W., Jiang J., Geiger J. D., and Selkoe D. J. (1997) Caffeine stimulates amyloid β-peptide release from β-amyloid precursor protein-transfected HEK293 cells. J. Neurochem. 69, 1580-1591.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1580-1591
-
-
Querfurth, H.W.1
Jiang, J.2
Geiger, J.D.3
Selkoe, D.J.4
-
167
-
-
17644429206
-
Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content
-
Racchi M., Baetta R., Salvietti N., Ianna P., Franceschini G., Paoletti R., Fumagalli R., Govoni S., Trabucchi M., and Soma M. (1997) Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content. Biochem. J. 322, 893-898.
-
(1997)
Biochem. J.
, vol.322
, pp. 893-898
-
-
Racchi, M.1
Baetta, R.2
Salvietti, N.3
Ianna, P.4
Franceschini, G.5
Paoletti, R.6
Fumagalli, R.7
Govoni, S.8
Trabucchi, M.9
Soma, M.10
-
168
-
-
0032521607
-
Bradykinin-induced amyloid precursor protein secretion: A protein kinase C-independent mechanism that is not altered in fibroblasts from patients with sporadic Alzheimer's disease
-
Racchi M., Ianna P., Binetti G., Trabucchi M., and Govoni S. (1998) Bradykinin-induced amyloid precursor protein secretion: a protein kinase C-independent mechanism that is not altered in fibroblasts from patients with sporadic Alzheimer's disease. Biochem. J. 330, 1271-1275.
-
(1998)
Biochem. J.
, vol.330
, pp. 1271-1275
-
-
Racchi, M.1
Ianna, P.2
Binetti, G.3
Trabucchi, M.4
Govoni, S.5
-
169
-
-
0031301274
-
Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs
-
Rawson R. B., Zelenski N. G., Nijhawan D., Ye J., Sakai J., Hasan M. T., Chang T. Y., Brown M. S., and Goldstein J. L. (1997) Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs. Mol. Cell 1, 47-57.
-
(1997)
Mol. Cell
, vol.1
, pp. 47-57
-
-
Rawson, R.B.1
Zelenski, N.G.2
Nijhawan, D.3
Ye, J.4
Sakai, J.5
Hasan, M.T.6
Chang, T.Y.7
Brown, M.S.8
Goldstein, J.L.9
-
170
-
-
0027374047
-
Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
-
Rebeck G. W., Reiter J. S., Strickland D. K., and Hyman B. T. (1993) Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron 11, 575-580.
-
(1993)
Neuron
, vol.11
, pp. 575-580
-
-
Rebeck, G.W.1
Reiter, J.S.2
Strickland, D.K.3
Hyman, B.T.4
-
171
-
-
0024466345
-
Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC12 cell cultures
-
Refolo L. M., Salton S. R., Anderson J. P., Mehta P., and Robakis N. K. (1989) Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC12 cell cultures. Biochem. Biophys. Res. Commun. 164, 664-670.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.164
, pp. 664-670
-
-
Refolo, L.M.1
Salton, S.R.2
Anderson, J.P.3
Mehta, P.4
Robakis, N.K.5
-
172
-
-
0031003537
-
Additive effects of basic fibroblast growth factor and phorbol ester on β-amyloid precursor protein expression and secretion
-
Ringheim G. E., Aschmies S., and Petko W. (1997) Additive effects of basic fibroblast growth factor and phorbol ester on β-amyloid precursor protein expression and secretion. Neurochem. Int. 30, 475-481.
-
(1997)
Neurochem. Int.
, vol.30
, pp. 475-481
-
-
Ringheim, G.E.1
Aschmies, S.2
Petko, W.3
-
173
-
-
0028071334
-
Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid β/A4 protein precursor
-
Roch J. M., Masliah E., Roch-Levecq A. C., Sundsmo M. P., Otero D. A., Veinbergs I., and Saitoh T. (1994) Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid β/A4 protein precursor. Proc. Natl. Acad. Sci. USA 91, 7450-7454.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7450-7454
-
-
Roch, J.M.1
Masliah, E.2
Roch-Levecq, A.C.3
Sundsmo, M.P.4
Otero, D.A.5
Veinbergs, I.6
Saitoh, T.7
-
174
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev E. I., Sherrington R., Rogaeva E. A., Levesque G., Ikeda M., Liang Y., Chi H., Lin C., Holman K., Tsuda T., Mar L., Sorbi S., Nacmias B., Piacentini S., Amaducci L., Chumakov I., Cohen D., Lannfelt L., Fraser P. E., Rommens J. M., and St. George-Hyslop P. H. (1995) Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376, 775-778.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, C.8
Holman, K.9
Tsuda, T.10
Mar, L.11
Sorbi, S.12
Nacmias, B.13
Piacentini, S.14
Amaducci, L.15
Chumakov, I.16
Cohen, D.17
Lannfelt, L.18
Fraser, P.E.19
Rommens, J.M.20
St George-Hyslop, P.H.21
more..
-
175
-
-
9444245809
-
Morphology and toxicity of Aβ-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease
-
Roher A. E., Chaney M. O., Kuo Y.-M., Webster S. D., Stine W. B., Haverkamp L. J., Woods A. S., Cotter R. J., Tuohy J. M., Krafft G. A., Bonnell B. S., and Emmerling M. R. (1996) Morphology and toxicity of Aβ-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease. J. Biol. Chem. 271, 20631-20635.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20631-20635
-
-
Roher, A.E.1
Chaney, M.O.2
Kuo, Y.-M.3
Webster, S.D.4
Stine, W.B.5
Haverkamp, L.J.6
Woods, A.S.7
Cotter, R.J.8
Tuohy, J.M.9
Krafft, G.A.10
Bonnell, B.S.11
Emmerling, M.R.12
-
176
-
-
0030273012
-
The Alzheimer diseases
-
Roses A. D. (1996) The Alzheimer diseases. Curr. Opin. Neurobiol. 6, 644-650.
-
(1996)
Curr. Opin. Neurobiol.
, vol.6
, pp. 644-650
-
-
Roses, A.D.1
-
177
-
-
0030722499
-
In vivo regulation of amyloid precursor protein secretion in rat neocortex by cholinergic activity
-
Rossner S., Ueberham U., Yu J., Kirazov L., Schliebs R., Perezpolo J. R., and Bigl V. (1997) In vivo regulation of amyloid precursor protein secretion in rat neocortex by cholinergic activity. Eur. J. Neurosci. 9, 2125-2134.
-
(1997)
Eur. J. Neurosci.
, vol.9
, pp. 2125-2134
-
-
Rossner, S.1
Ueberham, U.2
Yu, J.3
Kirazov, L.4
Schliebs, R.5
Perezpolo, J.R.6
Bigl, V.7
-
178
-
-
0026665014
-
Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells
-
Sambamurti K., Shioi J., Anderson J. P., Papolla M. A., and Robakis N. (1992) Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells. J. Neurosci. Res. 33, 319-329.
-
(1992)
J. Neurosci. Res.
, vol.33
, pp. 319-329
-
-
Sambamurti, K.1
Shioi, J.2
Anderson, J.P.3
Papolla, M.A.4
Robakis, N.5
-
179
-
-
0032032493
-
Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester
-
Savage M. J., Trusko S. P., Howland D. S., Pinsker L. R., Mistretta S., Reaume A. G., Greenberg B. D., Siman R., and Scott R. W. (1998) Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester. J. Neurosci. 18, 1743-1752.
-
(1998)
J. Neurosci.
, vol.18
, pp. 1743-1752
-
-
Savage, M.J.1
Trusko, S.P.2
Howland, D.S.3
Pinsker, L.R.4
Mistretta, S.5
Reaume, A.G.6
Greenberg, B.D.7
Siman, R.8
Scott, R.W.9
-
180
-
-
0028904272
-
Alzheimer's disease: Fundamental and therapeutics
-
Schorderet M. (1995) Alzheimer's disease: fundamental and therapeutics. Experientia 51, 99-105.
-
(1995)
Experientia
, vol.51
, pp. 99-105
-
-
Schorderet, M.1
-
181
-
-
0024810385
-
The regulation of amyloid β protein precursor secretion and its modulatory role in cell adhesion
-
Schubert D., Jin L.-W., Saitoh T., and Cole G. (1989a) The regulation of amyloid β protein precursor secretion and its modulatory role in cell adhesion. Neuron 3, 689-694.
-
(1989)
Neuron
, vol.3
, pp. 689-694
-
-
Schubert, D.1
Jin, L.-W.2
Saitoh, T.3
Cole, G.4
-
182
-
-
0024560146
-
Characterization of an amyloid β precursor protein that binds heparin and contains tyrosine sulfate
-
Schubert D., La Carbiere M., Saitoh T., and Cole G. (1989b) Characterization of an amyloid β precursor protein that binds heparin and contains tyrosine sulfate. Proc. Natl. Acad. Sci. USA 86, 2066-2069.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 2066-2069
-
-
Schubert, D.1
La Carbiere, M.2
Saitoh, T.3
Cole, G.4
-
184
-
-
12644290265
-
Evidence for phosphorylation and oligomeric assembly of presenilin I
-
Seeger M., Nordstedt C., Petanceska S., Kovacs D. M., Gouras G. K., Hahne S., Fraser P., Levesque L., Czernik A. J., St. George-Hyslop P., Sisodia S. S., Thinakaran G., Tanzi R. E., Greengard P., and Gandy S. (1997) Evidence for phosphorylation and oligomeric assembly of presenilin I. Proc. Natl. Acad. Sci. USA 94, 5090-5094.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5090-5094
-
-
Seeger, M.1
Nordstedt, C.2
Petanceska, S.3
Kovacs, D.M.4
Gouras, G.K.5
Hahne, S.6
Fraser, P.7
Levesque, L.8
Czernik, A.J.9
St George-Hyslop, P.10
Sisodia, S.S.11
Thinakaran, G.12
Tanzi, R.E.13
Greengard, P.14
Gandy, S.15
-
185
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe D. J. (1991) The molecular pathology of Alzheimer's disease. Neuron 6, 487-498.
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
186
-
-
0027367764
-
Physiological production of the β-amyloid protein and the mechanism of Alzheimer's disease
-
Selkoe D. J. (1993) Physiological production of the β-amyloid protein and the mechanism of Alzheimer's disease. Trends Neurosci. 16, 403-409.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 403-409
-
-
Selkoe, D.J.1
-
187
-
-
0028171885
-
Amyloid β-protein precursor: New clues to the genesis of Alzheimer's disease
-
Selkoe D. J. (1994) Amyloid β-protein precursor: new clues to the genesis of Alzheimer's disease. Curr. Opin. Neurobiol. 4, 708-716.
-
(1994)
Curr. Opin. Neurobiol.
, vol.4
, pp. 708-716
-
-
Selkoe, D.J.1
-
188
-
-
0031038918
-
Alzheimer's disease: Genotypes, phenotypes and treatments
-
Selkoe D. J. (1997) Alzheimer's disease: genotypes, phenotypes and treatments. Science 275, 630-631.
-
(1997)
Science
, vol.275
, pp. 630-631
-
-
Selkoe, D.J.1
-
189
-
-
0001067847
-
β-amyloid precursor protein of Alzheimer's disease occurs as 110-to 135-kilodalton membrane-associated proteins in neural and nonneuronal tissues
-
Selkoe D. J., Podlisny M. B., Joachin C. A., Vickers E. A., Lee G., Fritz L. C., and Oltersdorf T. (1988) β-amyloid precursor protein of Alzheimer's disease occurs as 110-to 135-kilodalton membrane-associated proteins in neural and nonneuronal tissues. Proc. Natl. Acad. Sci. USA 85, 7341-7345.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 7341-7345
-
-
Selkoe, D.J.1
Podlisny, M.B.2
Joachin, C.A.3
Vickers, E.A.4
Lee, G.5
Fritz, L.C.6
Oltersdorf, T.7
-
190
-
-
0029933153
-
The role of APP processing and trafficking pathways in the formation of amyloid β-protein
-
Selkoe D. J., Yamazaki M., Citron M., Podlisny M. B., Koo E. H., Teplow D. B., and Haass C. (1996) The role of APP processing and trafficking pathways in the formation of amyloid β-protein. Ann. NY Acad. Sci. 777, 57-64.
-
(1996)
Ann. NY Acad. Sci.
, vol.777
, pp. 57-64
-
-
Selkoe, D.J.1
Yamazaki, M.2
Citron, M.3
Podlisny, M.B.4
Koo, E.H.5
Teplow, D.B.6
Haass, C.7
-
191
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids
-
Seubert P., Vigo-Pelfrey C. Esch F., Lee M., Dovey H., Davis D., Sinha S., Schlossmacher M., Whaley J., Swindlehurst C., McCormack R., Wolfert R., Selkoe D., Lieberburg I., and Schenk D. (1992) Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids. Nature 359, 325-327.
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
Sinha, S.7
Schlossmacher, M.8
Whaley, J.9
Swindlehurst, C.10
McCormack, R.11
Wolfert, R.12
Selkoe, D.13
Lieberburg, I.14
Schenk, D.15
-
192
-
-
0027459686
-
Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide
-
Seubert P., Oltersdorf T., Lee M. G., Barbour R., Blomquist C., Davis D. L., Bryant K., Fritz, L. C., Galasko D., Thal L. J., Lieberburg I., and Schenk D. B. (1993) Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide. Nature 361, 260-263.
-
(1993)
Nature
, vol.361
, pp. 260-263
-
-
Seubert, P.1
Oltersdorf, T.2
Lee, M.G.3
Barbour, R.4
Blomquist, C.5
Davis, D.L.6
Bryant, K.7
Fritz, L.C.8
Galasko, D.9
Thal, L.J.10
Lieberburg, I.11
Schenk, D.B.12
-
193
-
-
0029004341
-
Cloning of a gene hearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R., Rogaev E. I., Liang Y., Rogaeva E. A., Levesque G., Ikeda M., Chi H., Lin C., Li G., Holman K., Tsuda T., Mar L., Foncin J.-F., Bruni A. C., Montesi M. P., Sorbi S., Rainera I., Pinessi L., Nee L., Chumakov I., Pollen D., Brookes A., Sanseau P., Polinsky R. J., Wasco W., Da Silva H. A. R., Haines J. L., Pericak-Vance M. A., Tanzi R. E., Roses A. D., Fraser P. E., Rommens J. M., and St. George-Hyslop P. H. (1995) Cloning of a gene hearing missense mutations in early-onset familial Alzheimer's disease. Nature 375, 754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.-F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Rainera, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Pollen, D.21
Brookes, A.22
Sanseau, P.23
Polinsky, R.J.24
Wasco, W.25
Da Silva, H.A.R.26
Haines, J.L.27
Pericak-Vance, M.A.28
Tanzi, R.E.29
Roses, A.D.30
Fraser, P.E.31
Rommens, J.M.32
St George-Hyslop, P.H.33
more..
-
194
-
-
0026760261
-
Production of the Alzheimer amyloid β protein by normal proteolytic processing
-
Shoji M., Golde T. E., Ghiso J., Cheung T. T., Estus S., Shaffer M., Cai X. D., McKay D. M., Tintner R., Frangione B., and Younkin S. G. (1992) Production of the Alzheimer amyloid β protein by normal proteolytic processing. Science 258, 126-129.
-
(1992)
Science
, vol.258
, pp. 126-129
-
-
Shoji, M.1
Golde, T.E.2
Ghiso, J.3
Cheung, T.T.4
Estus, S.5
Shaffer, M.6
Cai, X.D.7
McKay, D.M.8
Tintner, R.9
Frangione, B.10
Younkin, S.G.11
-
195
-
-
0029935765
-
Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons
-
Simons M., De Strooper B. D., Multhaup G., Tienari P. J., Dotti C. G., and Beyreuther K. (1996) Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons. J. Neurosci. 16, 899-908.
-
(1996)
J. Neurosci.
, vol.16
, pp. 899-908
-
-
Simons, M.1
De Strooper, B.D.2
Multhaup, G.3
Tienari, P.J.4
Dotti, C.G.5
Beyreuther, K.6
-
196
-
-
0032568552
-
Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons
-
Simons M., Keller P., De Strooper B., Beyreuther K., Dotti C. G., and Simons K. (1998) Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons. Proc. Natl. Acad. Sci. USA 95, 6460-6464.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
197
-
-
0026721943
-
β-Amyloid precursor protein cleavage by a membrane-bound protease
-
Sisodia S. S. (1992) β-Amyloid precursor protein cleavage by a membrane-bound protease. Proc. Natl. Acad. Sci. USA 89, 6075-6079.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6075-6079
-
-
Sisodia, S.S.1
-
198
-
-
0025373508
-
Evidence that β-amyloid protein in Alzheimer's disease is not derived by normal processing
-
Sisodia S. S., Koo E. H., Beyreuther K., Unterbeck A., and Price D. L. (1990) Evidence that β-amyloid protein in Alzheimer's disease is not derived by normal processing. Science 248, 492-495.
-
(1990)
Science
, vol.248
, pp. 492-495
-
-
Sisodia, S.S.1
Koo, E.H.2
Beyreuther, K.3
Unterbeck, A.4
Price, D.L.5
-
199
-
-
0027487188
-
Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase Cα
-
Slack B. E., Nitsch R. M., Livneh E., Kunz G. M., Breu J., Eldar H., and Wurtman R. J. (1993) Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase Cα. J. Biol. Chem. 268, 21097-21101.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21097-21101
-
-
Slack, B.E.1
Nitsch, R.M.2
Livneh, E.3
Kunz, G.M.4
Breu, J.5
Eldar, H.6
Wurtman, R.J.7
-
200
-
-
0028935040
-
Tyrosine phosphorylation of amyloid precursor protein secretion by the M3 muscarinic acetylcholine receptor
-
Slack B. E., Breu J., Petryniak M. A., Srivastava K., and Wurtman R. J. (1995) Tyrosine phosphorylation of amyloid precursor protein secretion by the M3 muscarinic acetylcholine receptor. J. Biol. Chem. 270, 8337-8344.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 8337-8344
-
-
Slack, B.E.1
Breu, J.2
Petryniak, M.A.3
Srivastava, K.4
Wurtman, R.J.5
-
201
-
-
0030723893
-
Rapid stimulation of amyloid precursor protein release by epidermal growth factor: Role of PKC
-
Slack B. E., Breu J., Muchnicki L., and Wurtman R. J. (1997) Rapid stimulation of amyloid precursor protein release by epidermal growth factor: role of PKC. Biochem. J. 327, 245-246.
-
(1997)
Biochem. J.
, vol.327
, pp. 245-246
-
-
Slack, B.E.1
Breu, J.2
Muchnicki, L.3
Wurtman, R.J.4
-
202
-
-
0028168596
-
Secreted forms of β-amyloid precursor protein protect against ischemic brain injury
-
Smith-Swintosky V. L., Pettigrew L. C., Craddock S. D., Culwell A. R., Rydel R. E., and Mattson M. P. (1994) Secreted forms of β-amyloid precursor protein protect against ischemic brain injury. J. Neurochem. 63, 781-784.
-
(1994)
J. Neurochem.
, vol.63
, pp. 781-784
-
-
Smith-Swintosky, V.L.1
Pettigrew, L.C.2
Craddock, S.D.3
Culwell, A.R.4
Rydel, R.E.5
Mattson, M.P.6
-
203
-
-
12044254746
-
Binding of human apolipoprotein E to synthetic amyloid β-peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
-
Strittmatter W. J., Weisgraber K. H., Huang D. Y., Dong L.-M., Salvesen G. S., Pericak-Vance M., Schmechel D., Saunders A. M., Goldgaber D., and Roses A. D. (1993a) Binding of human apolipoprotein E to synthetic amyloid β-peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90, 8098-8102.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8098-8102
-
-
Strittmatter, W.J.1
Weisgraber, K.H.2
Huang, D.Y.3
Dong, L.-M.4
Salvesen, G.S.5
Pericak-Vance, M.6
Schmechel, D.7
Saunders, A.M.8
Goldgaber, D.9
Roses, A.D.10
-
204
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter W. J., Saunders A. M., Schmechel D., Pericak-Vance M., Enghild J., Salvesen G. S., and Roses A. D. (1993b) Apolipoprotein E: high-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. USA 90, 1977-1981.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
205
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C., Abramowski D., Duke M., Wiederhold K. H., Mistl C., Rothacher S., Ledermann B., Bürki K., Frey P., Paganetti P. A., Waridel C., Calhoun M. E., Jucker M., Probst A., Staufenbiel M., and Sommer B. (1997) Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc. Natl. Acad. Sci. USA 94, 13287-13292.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Bürki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
206
-
-
0026750650
-
Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C
-
Suzuki T., Nairn A. C., Gandy S. E., and Greengard P. (1992) Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C. Neuroscience 48, 755-761.
-
(1992)
Neuroscience
, vol.48
, pp. 755-761
-
-
Suzuki, T.1
Nairn, A.C.2
Gandy, S.E.3
Greengard, P.4
-
207
-
-
0023109592
-
Amyloid β protein gene: CDNA, mRNA distribution and genetic linkage near the Alzheimer locus
-
Tanzi R. E., Gusella J. F., Watkins P. C., Bruns G. A., St. George-Hyslop P., Van Keuren M. L., Patterson D., Pagan S., Kurnit D. M., and Neve R. L. (1987) Amyloid β protein gene: cDNA, mRNA distribution and genetic linkage near the Alzheimer locus. Science 235, 880-884.
-
(1987)
Science
, vol.235
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
Bruns, G.A.4
St George-Hyslop, P.5
Van Keuren, M.L.6
Patterson, D.7
Pagan, S.8
Kurnit, D.M.9
Neve, R.L.10
-
208
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairments
-
Terry R. D., Masliah E., Salmon D. P., Butters N., DeTeresa R., Hill R., Hansen L. A., and Katzman R. (1991) Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairments. Ann. Neurol. 30, 572-580.
-
(1991)
Ann. Neurol.
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
DeTeresa, R.5
Hill, R.6
Hansen, L.A.7
Katzman, R.8
-
209
-
-
0025332577
-
Thapsigargin, a tumor promoter, discharges intracellular calcium stores by a specific inhibition of the endoplasmic reticulum
-
Thastrup O., Cullen P., Drobak B., Hanley M., and Dawdson A. (1990) Thapsigargin, a tumor promoter, discharges intracellular calcium stores by a specific inhibition of the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 87, 2466-2470.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2466-2470
-
-
Thastrup, O.1
Cullen, P.2
Drobak, B.3
Hanley, M.4
Dawdson, A.5
-
210
-
-
15844425969
-
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
-
Thinakaran G., Borchelt D. R., Lee M. K., Slum H. H., Spitzer L., Kim G., Ratovitsky T., Davenport F., Nordstedt C., Seeger M., Hardy J., Levey A. I., Gandy S. E., Jenkins N. A., Copeland N. G., Price D. L., and Sisodia S. S. (1996) Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron 17, 181-190.
-
(1996)
Neuron
, vol.17
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
Slum, H.H.4
Spitzer, L.5
Kim, G.6
Ratovitsky, T.7
Davenport, F.8
Nordstedt, C.9
Seeger, M.10
Hardy, J.11
Levey, A.I.12
Gandy, S.E.13
Jenkins, N.A.14
Copeland, N.G.15
Price, D.L.16
Sisodia, S.S.17
-
211
-
-
0030966774
-
Intracellular and secreted Alzheimer β-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons
-
Tienari P. J., Ida N., Ikonen E., Simons M., Weidemann A., Multhaup G., Masters C. L., Dotti C. G., and Beyreuther K. (1997) Intracellular and secreted Alzheimer β-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons. Proc. Natl. Acad. Sci. USA 94, 4125-4130.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4125-4130
-
-
Tienari, P.J.1
Ida, N.2
Ikonen, E.3
Simons, M.4
Weidemann, A.5
Multhaup, G.6
Masters, C.L.7
Dotti, C.G.8
Beyreuther, K.9
-
212
-
-
0029833865
-
β-Amyloid precursor protein: Location of transmembrane domain and specificity of γ-secretase cleavage
-
Tischer E. and Cordell B. (1996) β-Amyloid precursor protein: location of transmembrane domain and specificity of γ-secretase cleavage. J. Biol. Chem. 271, 21914-21919.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21914-21919
-
-
Tischer, E.1
Cordell, B.2
-
213
-
-
0032513060
-
Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway
-
Tomita S., Kirino Y., and Suzuki T. (1998) Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. J. Biol. Chem. 273, 6277-6284.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6277-6284
-
-
Tomita, S.1
Kirino, Y.2
Suzuki, T.3
-
214
-
-
0030036767
-
The estrogen/neurotrophin connection during neural development: Is co-localization of estrogen receptors with the neurotrophins and their receptors biologically relevant?
-
Toran-Allerand C. D. (1996) The estrogen/neurotrophin connection during neural development: is co-localization of estrogen receptors with the neurotrophins and their receptors biologically relevant? Dev. Neurosci. 18, 36-48.
-
(1996)
Dev. Neurosci.
, vol.18
, pp. 36-48
-
-
Toran-Allerand, C.D.1
-
215
-
-
0028283503
-
Molecular mechanisms of action of steroid/thyroid receptor superfamily members
-
Tsai M.-J. and O'Malley B. W. (1994) Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem. 63, 451-486.
-
(1994)
Annu. Rev. Biochem.
, vol.63
, pp. 451-486
-
-
Tsai, M.-J.1
O'Malley, B.W.2
-
217
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich A. and Schlessinger J. (1990) Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
218
-
-
0030974065
-
Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices
-
Ulus I. H. and Wurtman R. J. (1997) Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices. J. Pharmacol. Exp. Ther. 281, 149-154.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.281
, pp. 149-154
-
-
Ulus, I.H.1
Wurtman, R.J.2
-
219
-
-
0028171525
-
Interleukin-1β dissociates β-amyloid precursor protein and β-amyloid peptide secretion
-
Vasilakos J. P., Carroll R. T., Emmerling M. R., Doyle P. D., Davis R. E., Kim K. S., and Shivers B. D. (1994) Interleukin-1β dissociates β-amyloid precursor protein and β-amyloid peptide secretion. FEBS Lett. 354, 289-292.
-
(1994)
FEBS Lett.
, vol.354
, pp. 289-292
-
-
Vasilakos, J.P.1
Carroll, R.T.2
Emmerling, M.R.3
Doyle, P.D.4
Davis, R.E.5
Kim, K.S.6
Shivers, B.D.7
-
220
-
-
0031470093
-
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice
-
Vonkoch C. S., Zheng H., Chen H., Trumbauer M., Thinakaran G., Vanderploeg L. H. T., Price D. L., and Sisodia S. S. (1997) Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice. Neurobiol. Aging 18, 661-669.
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 661-669
-
-
Vonkoch, C.S.1
Zheng, H.2
Chen, H.3
Trumbauer, M.4
Thinakaran, G.5
Vanderploeg, L.H.T.6
Price, D.L.7
Sisodia, S.S.8
-
221
-
-
0029013955
-
Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats
-
Wallace W. C., Lieberburg I., Schenk D., Vigo-Pelfrey C., Davis K. L., and Haroutunian V. (1995) Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats. J. Neurosci. 15, 4896-4905.
-
(1995)
J. Neurosci.
, vol.15
, pp. 4896-4905
-
-
Wallace, W.C.1
Lieberburg, I.2
Schenk, D.3
Vigo-Pelfrey, C.4
Davis, K.L.5
Haroutunian, V.6
-
222
-
-
12644264304
-
Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C
-
Walter J., Grunberg J., Capell A., Pesold B., Schindzielorz A., Citron M., Mendla K., St. George-Hyslop P., Multhaup G., Selkoe D. J., and Haass C. (1997) Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C. Proc. Natl. Acad. Sci. USA 94, 5349-5354.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5349-5354
-
-
Walter, J.1
Grunberg, J.2
Capell, A.3
Pesold, B.4
Schindzielorz, A.5
Citron, M.6
Mendla, K.7
St George-Hyslop, P.8
Multhaup, G.9
Selkoe, D.J.10
Haass, C.11
-
223
-
-
0026045172
-
Release of the β/A4 amyloid precursor protein: Identification of a cleavage site in cultured mammalian cells
-
Wang R., Meschia J. F., Cotter R. J., and Sisodia S. S. (1991) Release of the β/A4 amyloid precursor protein: identification of a cleavage site in cultured mammalian cells. J. Biol. Chem. 266, 16960-16964.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 16960-16964
-
-
Wang, R.1
Meschia, J.F.2
Cotter, R.J.3
Sisodia, S.S.4
-
224
-
-
0024550204
-
Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein
-
Weidemann A., Konig G., Bunke D., Fischer P., Salbaum J. M., Master C. L., and Beyreuther K. (1989) Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57, 115-126.
-
(1989)
Cell
, vol.57
, pp. 115-126
-
-
Weidemann, A.1
Konig, G.2
Bunke, D.3
Fischer, P.4
Salbaum, J.M.5
Master, C.L.6
Beyreuther, K.7
-
225
-
-
0031054505
-
Formation of stable complexes between two Alzheimer's disease gene products: Presenilin-2 and β-amyloid precursor protein
-
Weidemann A., Paliga K., Durrwang U., Czech C. Evin G., Masters C. L., and Beyreuther K. (1997) Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and β-amyloid precursor protein. Nat. Med. 3, 328-332.
-
(1997)
Nat. Med.
, vol.3
, pp. 328-332
-
-
Weidemann, A.1
Paliga, K.2
Durrwang, U.3
Czech, C.4
Evin, G.5
Masters, C.L.6
Beyreuther, K.7
-
226
-
-
0027361386
-
Human neurons derived from teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular β-amyloid or A4 peptide
-
Wertkin A. M., Turner R. S., Pleasure S. J., Golde T. E., Younkin S. G., Trojanowski J. Q., and Lee V. M.-Y. (1993) Human neurons derived from teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular β-amyloid or A4 peptide. Proc. Natl. Acad. Sci. USA 90, 9513-9517.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9513-9517
-
-
Wertkin, A.M.1
Turner, R.S.2
Pleasure, S.J.3
Golde, T.E.4
Younkin, S.G.5
Trojanowski, J.Q.6
Lee, V.M.-Y.7
-
227
-
-
0030993634
-
Estrogen stakes claim to cognition
-
Wickelgren I. (1997) Estrogen stakes claim to cognition. Science 276, 675-678.
-
(1997)
Science
, vol.276
, pp. 675-678
-
-
Wickelgren, I.1
-
228
-
-
0030952217
-
Intracellular generation and accumulation of amyloid β-peptide terminating at amino acid 42
-
Wild-Bode C., Yamazaki T., Capell A., Leimer U., Steiner H., Ihara Y., and Haass C. (1997) Intracellular generation and accumulation of amyloid β-peptide terminating at amino acid 42. J. Biol. Chem. 272, 16085-16088.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16085-16088
-
-
Wild-Bode, C.1
Yamazaki, T.2
Capell, A.3
Leimer, U.4
Steiner, H.5
Ihara, Y.6
Haass, C.7
-
229
-
-
0028926941
-
Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid β-protein production in human neuronal NT2N cells
-
Wolf B. A., Wertkin A. M., Jolly Y. C., Yasuda R. P., Wolfe B. B., Konrad R. J., Manning D., Ravi S., Williamson J. R., and Lee V. M.-Y. (1995) Muscarinic regulation of Alzheimer's disease amyloid precursor protein secretion and amyloid β-protein production in human neuronal NT2N cells. J. Biol. Chem. 270, 4916-4922.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4916-4922
-
-
Wolf, B.A.1
Wertkin, A.M.2
Jolly, Y.C.3
Yasuda, R.P.4
Wolfe, B.B.5
Konrad, R.J.6
Manning, D.7
Ravi, S.8
Williamson, J.R.9
Lee, V.M.-Y.10
-
230
-
-
0344885854
-
Transforming growth factor β induces Aβ-responsive calcium currents in neurons
-
Wolozin B., Hirashima N., Luo Y., Li Y., Alkon D., Etcheberrigaray R., and Sunderland T. (1995) Transforming growth factor β induces Aβ-responsive calcium currents in neurons. Neuroreport 6, 1301-1305.
-
(1995)
Neuroreport
, vol.6
, pp. 1301-1305
-
-
Wolozin, B.1
Hirashima, N.2
Luo, Y.3
Li, Y.4
Alkon, D.5
Etcheberrigaray, R.6
Sunderland, T.7
-
231
-
-
0029983524
-
Differential regulation of APP secretion by apolipoprotein E3 and E4
-
Wolozin B. L., Jasaric-Keys J., Canter R., Li Y., Vanderputten D., and Sunderland T. (1996) Differential regulation of APP secretion by apolipoprotein E3 and E4. Ann. NY Acad. Sci. 777, 322-326.
-
(1996)
Ann. NY Acad. Sci.
, vol.777
, pp. 322-326
-
-
Wolozin, B.L.1
Jasaric-Keys, J.2
Canter, R.3
Li, Y.4
Vanderputten, D.5
Sunderland, T.6
-
232
-
-
0030753089
-
Interaction between amyloid precursor protein and presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer's disease
-
Xia W., Zhang J., Perez R., Koo E. H., and Selkoe D. J. (1997) Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 94, 8208-8213.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8208-8213
-
-
Xia, W.1
Zhang, J.2
Perez, R.3
Koo, E.H.4
Selkoe, D.J.5
-
233
-
-
0028859466
-
Regulated formation of Golgi secretory vesicles containing Alzheimer β-amyloid precursor protein
-
Xu H., Greengard P., and Gandy S. (1995) Regulated formation of Golgi secretory vesicles containing Alzheimer β-amyloid precursor protein. J. Biol. Chem. 270, 23243-23245.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23243-23245
-
-
Xu, H.1
Greengard, P.2
Gandy, S.3
-
234
-
-
0029863203
-
Metabolism of Alzheimer β-amyloid precursor protein: Regulation by protein kinase A in intact cells and in a cell-free system
-
Xu H., Sweeney D., Greengard P., and Gandy S. (1996) Metabolism of Alzheimer β-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free system. Proc. Natl. Acad. Sci. USA 93, 4081-4084.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4081-4084
-
-
Xu, H.1
Sweeney, D.2
Greengard, P.3
Gandy, S.4
-
235
-
-
0031946864
-
Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides
-
Xu H., Gouras G. K., Greenfield J. P., Vincent B., Naslund J., Mazzarelli L., Fried G., Jovanovic J. N., Seeger M., Relkin N. R., Liao F., Checler F., Buxbaum J. D., Chait B. T., Thinakaran G., Sisodia S. S., Wang R., Greengard P., and Gandy S. (1998) Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides. Nat. Med. 4, 447-451.
-
(1998)
Nat. Med.
, vol.4
, pp. 447-451
-
-
Xu, H.1
Gouras, G.K.2
Greenfield, J.P.3
Vincent, B.4
Naslund, J.5
Mazzarelli, L.6
Fried, G.7
Jovanovic, J.N.8
Seeger, M.9
Relkin, N.R.10
Liao, F.11
Checler, F.12
Buxbaum, J.D.13
Chait, B.T.14
Thinakaran, G.15
Sisodia, S.S.16
Wang, R.17
Greengard, P.18
Gandy, S.19
-
236
-
-
0029076397
-
Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide
-
Yan S. D., Yan S. F., Chen X., Fu J., Chen M., Kuppusamy P., Smith M. A., Perry G., Godman G. C., Nawroth P., Zweirer J. L., and Stern D. (1995) Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide. Nat. Med. 1, 693-699.
-
(1995)
Nat. Med.
, vol.1
, pp. 693-699
-
-
Yan, S.D.1
Yan, S.F.2
Chen, X.3
Fu, J.4
Chen, M.5
Kuppusamy, P.6
Smith, M.A.7
Perry, G.8
Godman, G.C.9
Nawroth, P.10
Zweirer, J.L.11
Stern, D.12
-
237
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid β protein: Reversal by tachykinin neuropeptides
-
Yankner B. A., Duffy L. K., and Kirschner D. A. (1990) Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 250, 279-282.
-
(1990)
Science
, vol.250
, pp. 279-282
-
-
Yankner, B.A.1
Duffy, L.K.2
Kirschner, D.A.3
-
238
-
-
0025989554
-
Modulation of membrane function by cholesterol
-
Yeagle P. L. (1991) Modulation of membrane function by cholesterol. Biochimie 73, 1303-1310.
-
(1991)
Biochimie
, vol.73
, pp. 1303-1310
-
-
Yeagle, P.L.1
-
239
-
-
0027988046
-
Focal adhesion kinase expressed by nerve cell lines shows increased tyrosine phosphorylation in response to Alzheimer's Aβ peptide
-
Zhang C., Lambert M. P., Bunch C., Barber K., Wade W. S., Krafft G. A., and Klein W. L. (1994) Focal adhesion kinase expressed by nerve cell lines shows increased tyrosine phosphorylation in response to Alzheimer's Aβ peptide. J. Biol. Chem. 269, 25247-25250.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25247-25250
-
-
Zhang, C.1
Lambert, M.P.2
Bunch, C.3
Barber, K.4
Wade, W.S.5
Krafft, G.A.6
Klein, W.L.7
-
240
-
-
0028988801
-
β-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
-
Zheng H., Jiang M., Trumbauer M. E., Sirinathsinghji D. J. S., Hopkins R., Smith D. W., Heavens R. P., Dawson G. R., Boyce S., Conner M. W., Stevens K. A., Slunt H. H., Sisodia S. S., Chen H. Y., and Van der Ploeg L. H. T. (1995) β-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell 81, 525-531.
-
(1995)
Cell
, vol.81
, pp. 525-531
-
-
Zheng, H.1
Jiang, M.2
Trumbauer, M.E.3
Sirinathsinghji, D.J.S.4
Hopkins, R.5
Smith, D.W.6
Heavens, R.P.7
Dawson, G.R.8
Boyce, S.9
Conner, M.W.10
Stevens, K.A.11
Slunt, H.H.12
Sisodia, S.S.13
Chen, H.Y.14
Van Der Ploeg, L.H.T.15
|