Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines

Journal of Neurochemistry

Volumn 90, Issue 6, 2004, Pages 1489-1499

  Zimmermann, Martina ^a   Gardoni, Fabrizio ^a   Marcello, Elena ^a   Colciaghi, Francesca ^a   Borroni, Barbara ^b   Padovani, Alessandro ^b   Cattabeni, Flaminio ^a   Di Luca, Monica ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Acetylcholinesterase; ADAM 10; Alzheimer's disease; Donepezil; Neuroblastoma; Trafficking

Indexed keywords

ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; CHOLINESTERASE INHIBITOR; DONEPEZIL; METALLOPROTEINASE; METALLOPROTEINASE ADAM 10; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CANCER CELL CULTURE; CELL LYSATE; CELL MEMBRANE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE ACTIVITY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROPHARMACOLOGY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN PROCESSING; PROTEIN TRANSPORT;

ACETYLCHOLINESTERASE; ADAM PROTEINS; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ATROPINE; BLOTTING, WESTERN; BREFELDIN A; BUNGAROTOXINS; CARBACHOL; CELL DIFFERENTIATION; CELL FRACTIONATION; CELL LINE, TUMOR; CHOLINERGIC AGONISTS; CHOLINESTERASE INHIBITORS; DRUG INTERACTIONS; EMBRYO; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INDANS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; MICROSCOPY, CONFOCAL; MUSCARINIC ANTAGONISTS; NEUROBLASTOMA; PHYSOSTIGMINE; PIPERIDINES; PROTEIN SYNTHESIS INHIBITORS; PROTEIN TRANSPORT; TRETINOIN;

EID: 4544239545     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02680.x     Document Type: Article

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