Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 10, 2001, Pages 5856-5861

  Fassbender, K ^a   Simons, M ^b   Bergmann, C ^a   Stroick, M ^a   Lutjohann D ^c   Keller, P ^d   Runz, H ^a   Kuhl S ^a   Bertsch, T ^a   Von Bergmann, K ^c   Hennerici, M ^a   Beyreuther, K ^a   Hartmann, T ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF BONN   (Germany)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; CHOLESTEROL; MEVINOLIN; SIMVASTATIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN HOMOGENATE; CONTROLLED STUDY; DEMENTIA; FETUS; GUINEA PIG; HIPPOCAMPUS; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; RISK FACTOR;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ANTICHOLESTEREMIC AGENTS; CHOLESTEROL; GENETIC PREDISPOSITION TO DISEASE; GUINEA PIGS; MUTATION; PEPTIDE FRAGMENTS; PROTEIN ISOFORMS; REFERENCE STANDARDS; SIMVASTATIN;

ANIMALIA; CAVIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0001504829     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.081620098     Document Type: Article

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