Presenilin 1 Independently Regulates β-Catenin Stability and Transcriptional Activity

Journal of Biological Chemistry

Volumn 276, Issue 51, 2001, Pages 48554-48561

  Killick, Richard ^a   Pollard, Claire C ^a   Asuni, Ayodeji A ^a   Mudher, Amrit K ^a   Richardson, Jill C ^b   Rupniak, H Tom ^b   Sheppard, Paul W ^c   Varndell, Ian M ^c   Brion, Jean Paul ^d   Levey, Allan I ^e   Levy, Oren A ^e   Vestling, Monika ^f   Cowburn, Richard ^f   Lovestone, Simon ^a   Anderton, Brian H ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Affiniti Research Products Ltd   (United Kingdom)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; FRACTIONATION; MICROSCOPIC EXAMINATION; MUTAGENESIS;

TRANSCRIPTION ASSAYS;

PROTEINS;

BETA CATENIN; PRESENILIN 1; WNT PROTEIN; CYTOSKELETON PROTEIN; FRAT PROTEIN; LITHIUM; LUCIFERASE; MEMBRANE PROTEIN; ONCOPROTEIN; PROTO ONCOGENE PROTEIN INT 1; PROTO ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEIN INT-1; S182 PROTEIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; EMBRYO; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; TRANSCRIPTION REGULATION; WILD TYPE; ANIMAL; CELL FRACTIONATION; CELL LINE; FLUORESCENCE MICROSCOPY; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALIA;

ANIMAL; BLOTTING, WESTERN; CELL LINE; CELL NUCLEUS; CYTOPLASM; CYTOSKELETAL PROTEINS; HUMAN; LITHIUM; LUCIFERASE; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION, GENETIC;

EID: 0035930522     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.m108332200     Document Type: Article

References (47)

1. Haass, C., and Baumeister, R. (1999) Eur. Arch. Psychiatry Clin. Neurosci. 249, 23-27
2. Scheuner, D., Eckman, C., Jensen, M., Song, X., Citron, M., Suzuki, N., Bird, T. D., Hardy, J., Hutton, M., Kukull, W., Larson, E., Levy-Lahad, E., Viitanen, M., Peskind, E., Poorkaj, P., Schellenberg, G., Tanzi, R., Wisco, W., Lannfelt, L., Selkoe, D., and Younkin, S. (1996) Nat. Med. 2, 864-870
3. Borchelt, D. R., Thinakaran, G., Eckman, C. B., Lee, M. K., Davenport, F., Ratovitsky, T., Prada, C. M., Kim, G., Seekins, S., Yager, D., Slunt, H. H., Wang, R., Seeger, M., Levey, A. I., Gandy, S. E., Copeland, N. G., Jenkins, N. A., Price, D. L., Younkin, S. G., and Sisodia, S. S. (1996) Neuron 17, 1005-1013
4. Citron, M., Westaway, D., Xia, W., Carlson, G., Diehl, T., Levesque, G., Johnson-Wood, K. Lee, M., Seubert, P., Davis, A., Kholodenko, D., Matter, R., Sherrington, H., Perry, B., Yao, H., Strome, R., Lieberburg, I., Rommens, J., Kim, S., Schenk, D., Fraser, P., St. George Hyslop, P., and Selkoe, D. J. (1997) Nat. Med. 3, 67-72
5. De Strooper, B., Saftig, P., Craessaerts, K., Vanderstichele, H., Guhde, G., Annaert, W., Von Figura, K., and Van Leuven, F. (1998) Nature 391, 387-390
6. Duff K., Eckman, C., Zehr, C., Yu, X., Prada, C. M., Perez-tur, J., Hutton, M., Buee, L., Harigaya, Y., Yager, D., Morgan, D., Gordon, M. N., Holcomb, L., Refolo, L., Zenk, B., Hardy, J., and Younkin, S. (1996) Nature 383, 710-713
7. Annaert, W. G., Levesque, L., Craessaerts, K., Dierinck, I., Snellings, G., Westaway, D., George-Hyslop, P. S., Cordell, B., Fraser, P., and De Strooper, B. (1999) J. Cell Biol. 147, 277-294
8. Li, Y. M., Xu, M., Lai, M. T., Huang, Q., Castro, J. L., DiMuzio-Mower, J., Harrison, T., Lellis, C., Nadin, A., Neduvelil, J. G., Register, H. B., Sardana, M. K., Shearman, M. S., Smith, A. L., Shi, X. P., Yin, K. C., Shafer, J. A., and Gardell, S. J. (2000) Nature 405, 689-694
9. Li, Y. M., Lai, M. T., Xu, M., Huang, Q., DiMuzio-Mower, J., Sardana, M. K., Shi, X. P., Yin, K. C., Shafer, J. A., and Gardell, S. J. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 6138-6143
10. Kimberly, W. T., Xia, W., Rahmati, T., Wolfe, M. S., and Selkoe, D. J. (2000) J. Biol. Chem. 275, 3173-3178
11. Zhang, Z., Nadeau, P., Song, W., Donoviel, D., Yuan, M., Bernstein, A., and Yankner, B. A. (2000) Nat. Cell Biol. 2, 463-465
12. De Strooper, B., Annaert, W., Cupers, P., Saftig, P., Craessaerts, K., Mumm, J. S., Schroeter, E. H., Schrijvers, V., Wolfe, M. S., Ray, W. J., Goate, A., and Kopan, R. (1999) Nature 398, 518-522
13. Struhl, G., and Greenwald, I. (1999) Nature 398, 522-525
14. Zhou, J., Liyanage, U., Medina, M., Ho, C., Simmons, A. D., Lovett, M., and Kosik, K S. (1997) Neuroreport 8, 2085-2090
15. Murayama, M., Tanaka, S., Palacino, J., Murayama, O., Honda, T., Sun, X., Yasutake, K., Nihonmatsu, N., Wolozin, B., and Takashima, A. (1998) FEBS Lett. 433, 73-77
16. Levesque, G., Yu, G., Nishimura, M., Zhang, D. M., Levesque, L., Yu, H., Xu, D., Liang, Y., Rogaeva, E., Ikeda, M., Duthie, M., Murgolo, N., Wang, L., VanderVere, P., Bayne, M. L., Strader, C. D., Rommens, J. M., Fraser, P. E., and St. George-Hyslop, P. (1999) J. Neurochem. 72, 999-1008
17. Kang, D. E., Soriano, S., Frosch, M. P., Collins, T., Naruse, S., Sisodia, S. S., Leibowitz, G., Levine, F., and Koo, E. H. (1999) J. Neurosci. 19, 4229-4237
18. Nishimura, M., Yu, G., Levesque, G., Zhang, D. M., Ruel, L., Chen, F., Milman, P., Holmes, E., Liang, Y., Kawarai, T., Jo, E., Supala, A., Rogaeva, E., Xu, D. M., Janus, C., Levesque, L., Bi, Q., Duthie, M., Rozmahel, H., Mattila, K., Lannfelt, L., Westaway, D., Mount, H. T., Woodgett, J., St. George-Hyslop, P., et al. (1999) Nat. Med. 5, 164-169
19. Zhang, Z., Hartmann, H., Do, V. M., Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., van de Wetering, M., Clevers, H., Saftig, P., De Strooper, B., He, X., and Yankner, B. A. (1998) Nature 395, 698-702
20. Soriano, S., Kang, D. E., Fu, M., Pestell, R., Chevallier, N., Zheng, H., and Koo, E. H. (2001) J. Cell Biol. 152, 785-794
21. Cox, R. T., McEwen, D. G., Myster, D. L., Duronio, R. J., Loureiro, J., and Peifer, M. (2000) Genetics 155, 1725-1740
22. Noll, E., Medina, M., Hartley, D., Zhou, J., Perrimon, N., and Kosik, K. S. (2000) Dev. Biol. 227, 450-464
23. Kirschenbaum, F., Hsu, S. C., Cordell, B., and McCarthy, J. V. (2001) J. Biol. Chem. 276, 7366-7375
24. Kawamura, Y., Kikuchi, A., Takada, R., Takada, S., Sudoh, S., Shibamoto, S., Yanagisawa, K., and Komano, H. (2001) Eur. J. Biochem. 268, 3036-3041
25. Mudher, A., Chapman, S., Richardson, J., Asuni, A., Gibb, G., Pollard, C., Killick, R., Iqbal, T., Raymond, L., Varndell, I., Sheppard, P., Makoff, A., Gower, E., Soden, P. E., Lewis, P., Murphy, M., Golde, T. E., Rupniak, H. T., Anderton, B. H., and Lovestone, S. (2001) J. Neurosci. 21, 4987-4995
26. Laemmli, U. K. (1970) Nature 227, 680-685
27. Sakanaka, C., Weiss, J. B., and Williams, L. T. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3020-3023
28. Krylova, O., Messenger, M. J., and Salinas, P. C. (2000) J. Cell Biol. 151, 83-94
29. Kishida, S., Yamamoto, H., Hino, S., Ikeda, S., Kishida, M., and Kikuchi, A. (1999) Mol. Cell. Biol. 19, 4414-4422
30. Smalley, M. J., Sara, E., Paterson, H., Naylor, S., Cook, D., Jayatilake, H., Fryer, L. G., Hutchinson, L., Fry, M. J., and Dale, T. C. (1999) EMBO J. 18, 2823-2835
31. Li, L., Yuan, H., Weaver, C. D., Mao, J., Farr, G. H., III, Sussman, D. J., Jonkers, J., Kimelman, D., and Wu, D. (1999) EMBO J. 18, 4233-4240
32. Salic, A., Lee, E., Mayer, L., and Kirschner, M. W. (2000) Mol. Cell 5, 523-532
33. Thomas, G. M., Frame, S., Goedert, M., Nathke, I., Polakis, P., and Cohen, P. (1999) FEBS Lett. 458, 247-251
34. Stambolic, V., Ruel, L., and Woodgett, J. R. (1996) Curr. Biol. 6, 1664-1668
35. Xia, X., Qian, S., Soriano, S., Wu, Y., Fletcher, A. M., Wang, X. J., Koo, E. H., Wu, X., and Zheng, H. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 10863-10868
36. Gottardi, C. J., Wong, E., and Gumbiner, B. M. (2001) J. Cell Biol. 153, 1049-1060
37. Walter, J., Capell, A., Grunberg, J., Pesold, B., Schindzielorz, A., Prior, R., Podlisny, M. B., Fraser, P., Hyslop, P. S., Selkoe, D. J., and Haass, C. (1996) Mol. Med. 2, 673-691
38. Kovacs, D. M., Fausett, H. J., Page, K. J., Kim, T. W., Moir, R. D., Merriam, D. E., Hollister, R. D., Hallmark, O. G., Mancini, R., Felsenstein, K. M., Hyman, B. T., Tanzi, R. E., and Wasco, W. (1996) Nat. Med. 2, 224-229
39. Georgakopoulos, A., Marambaud, P., Efthimiopoulos, S., Shioi, J., Cui, W., Li, H. C., Schutte, M., Gordon, R., Holstein, G. R., Martinelli, G., Mehta, P., Friedrich, V. L., Jr., and Robakis, N. K. (1999) Mol. Cell 4, 893-902
40. Li, J., Xu, M., Zhou, H., Ma, J., and Potter, H. (1997) Cell 90, 917-927
41. Baki, L., Marambaud, P., Efthimiopoulos, S., Georgakopoulos, A., Wen, P., Cui, W., Shioi, J., Koo, E., Ozawa, M., Friedrich, V. L., Jr., and Robakis, N. K. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 2381-2386
42. Roura, S., Miravet, S., Piedra, J., Garcia de Herreros, A., and Dunach, M. (1999) J. Biol. Chem. 274, 36734-36740
43. Piedra, J., Martinez, D., Castano, J., Miravet, S., Dunach, M., and de Herreros, A. G. (2001) J. Biol. Chem. 276, 20436-20443
44. Kwon, Y. T., Gupta, A., Zhou, Y., Nikolic, M., and Tsai, L. H. (2000) Curr. Biol. 10, 363-372
45. Kesavapany, S., Lau, K. F., McLoughlin, D. M., Brownlees, J., Ackerley, S., Leigh, P. N., Shaw, C. E., and Miller, C. C. (2001) Eur. J. Neurosci. 13, 241-247
46. Maccioni, R. B., Otth, C., Concha, II, and Munoz, J. P. (2001) Eur. J. Biochem. 268, 1518-1527
47. Patrick, G. N., Zukerberg, L., Nikolic, M., de la Monte, S., Dikkes, P., and Tsai, L. H. (1999) Nature 402, 615-622