Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP

Science

Volumn 293, Issue 5534, 2001, Pages 1487-1491

  Lewis, J ^a   Dickson, D W ^a   Lin, W L ^a   Chisholm, L ^a   Corral, A ^a   Jones, G ^a   Yen, S H ^a   Sahara, N ^a   Skipper, L ^a   Yager, D ^a   Eckman, C ^a   Hardy, J ^a   Hutton, M ^a   McGowan, E ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; MUTAGENS; PATHOLOGY; PROTEINS;

TAU PROTEINS;

GENETIC ENGINEERING;

AMYLOID PRECURSOR PROTEIN; MUTANT PROTEIN; TAU PROTEIN;

GENETICS; NEUROLOGY;

AGE; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; LIMBIC SYSTEM; MOTOR DYSFUNCTION; MOUSE; NEUROFIBRILLARY TANGLE; NONHUMAN; OLFACTORY CORTEX; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; FEMALE; LIMBIC SYSTEM; MALE; MICE; MICE, TRANSGENIC; MUTATION; NERVE DEGENERATION; NEUROFIBRILLARY TANGLES; NEURONS; PEPTIDE FRAGMENTS; RNA, MESSENGER; SENILE PLAQUES; SEX CHARACTERISTICS; SOLUBILITY; SPINAL CORD; TAU PROTEINS;

ANIMALIA; MUS MUSCULUS;

EID: 17944382037     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1058189     Document Type: Article

References (48)