Acyl-coenzyme A: Cholesterol acyltransferase modulates the generation of the amyloid β-peptide

Nature Cell Biology

Volumn 3, Issue 10, 2001, Pages 905-912

  Puglielli, Luigi ^a   Konopka, Genevieve ^b   Pack Chung, Eunju ^a   Ingano, Laura A MacKenzie ^a   Berezovska, Oksana ^a   Hyman, Bradley T ^a   Chang, Ta Yuan ^c   Tanzi, Rudolph E ^a   Kovacs, Dora M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; AMYLOID BETA PROTEIN; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; CHOLESTEROL ESTER; CP 113 818; ENZYME INHIBITOR; LECIMIBIDE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BIOCHEMISTRY; CATALYSIS; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; CORRELATION FUNCTION; EMBRYO; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME MECHANISM; METABOLIC REGULATION; MODULATION; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PATHOGENESIS; PEPTIDE SYNTHESIS; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; TREATMENT PLANNING;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BIOLOGICAL MARKERS; CELL FRACTIONATION; CELL LINE; CHOLESTEROL; ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; INTRACELLULAR MEMBRANES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; NEURONS; PRESENILIN-1; PYRIDINES; STEROL O-ACYLTRANSFERASE;

ANIMALIA;

EID: 0034795651     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1001-905     Document Type: Article

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