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Volumn 83, Issue 6, 2002, Pages 1529-1533

Spatial learning deficit in transgenic mice that conditionally over-express GSK-3β in the brain but do not form tau filaments

Author keywords

Alzheimer's disease; GSK 3; Spatial learning; Tau; Transgenic mice

Indexed keywords

BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3; TAU PROTEIN;

EID: 1642363745     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01269.x     Document Type: Article
Times cited : (305)

References (27)
  • 2
    • 0035087123 scopus 로고    scopus 로고
    • Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death
    • Cross D. A., Culbert A. A., Chalmers K. A., Facci L., Skaper S. D. and Reith A. D. (2001) Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death. J. Neurochem. 77, 94-102.
    • (2001) J. Neurochem. , vol.77 , pp. 94-102
    • Cross, D.A.1    Culbert, A.A.2    Chalmers, K.A.3    Facci, L.4    Skaper, S.D.5    Reith, A.D.6
  • 3
    • 0036090823 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: An emerging therapeutic target
    • Eldar-Finkelman H. (2002) Glycogen synthase kinase 3: An emerging therapeutic target. Trends Mol. Med. 8, 126-132.
    • (2002) Trends Mol. Med. , vol.8 , pp. 126-132
    • Eldar-Finkelman, H.1
  • 4
    • 0035943436 scopus 로고    scopus 로고
    • Formation of neurofibrillary tangles in P3011 tau transgenic mice induced by Abeta 42 fibrils
    • Gotz J., Chen F., van Dorpe J. and Nitsch R. M. (2001) Formation of neurofibrillary tangles in P3011 tau transgenic mice induced by Abeta 42 fibrils. Science 293, 1491-1495.
    • (2001) Science , vol.293 , pp. 1491-1495
    • Gotz, J.1    Chen, F.2    Van Dorpe, J.3    Nitsch, R.M.4
  • 5
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
    • Grimes C. A. and Jope R. S. (2001) The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog. Neurobiol. 65, 391-426.
    • (2001) Prog. Neurobiol. , vol.65 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 6
    • 0030868557 scopus 로고    scopus 로고
    • Lithium reduces tau phosphorylafion by inhibition of glycogen synthase kinase-3
    • Hong M., Chen D. C., Klein P. S. and Lee V. M. (1997) Lithium reduces tau phosphorylafion by inhibition of glycogen synthase kinase-3. J. Biol. Chem. 272, 25326-25332.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25326-25332
    • Hong, M.1    Chen, D.C.2    Klein, P.S.3    Lee, V.M.4
  • 7
    • 0031045216 scopus 로고    scopus 로고
    • Physiology and pathology of tau protein kinases in relation to Alzheimer's disease
    • Imahori K. and Uchida T. (1997) Physiology and pathology of tau protein kinases in relation to Alzheimer's disease. J. Biochem. (Tokyo) 121, 179-188.
    • (1997) J. Biochem. (Tokyo) , vol.121 , pp. 179-188
    • Imahori, K.1    Uchida, T.2
  • 9
    • 0035680685 scopus 로고    scopus 로고
    • FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain
    • Lim F., Hernandez F., Lucas J. J., Gomez-Ramos P., Moran M. A. and Avila J. (2001) FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain. Mol. Cell Neurosci. 18, 702-714.
    • (2001) Mol. Cell Neurosci. , vol.18 , pp. 702-714
    • Lim, F.1    Hernandez, F.2    Lucas, J.J.3    Gomez-Ramos, P.4    Moran, M.A.5    Avila, J.6
  • 11
    • 17544403592 scopus 로고    scopus 로고
    • Nuclear localization of beta-catenin in adult mouse thalamus correlates with low levels of GSK-3beta
    • Lucas J. J., Hernandez F. and Avila J. (1999) Nuclear localization of beta-catenin in adult mouse thalamus correlates with low levels of GSK-3beta. Neuroreport 10, 2699-2703.
    • (1999) Neuroreport , vol.10 , pp. 2699-2703
    • Lucas, J.J.1    Hernandez, F.2    Avila, J.3
  • 12
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • Lucas J. J., Hernandez F., Gomez-Ramos P., Moran M. A., Hen R. and Avila J. (2001) Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J. 20, 27-39.
    • (2001) EMBO J. , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernandez, F.2    Gomez-Ramos, P.3    Moran, M.A.4    Hen, R.5    Avila, J.6
  • 13
    • 0035889973 scopus 로고    scopus 로고
    • Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease
    • Martin-Aparicio E., Yamamoto A., Hernandez F., Hen R., Avila J. and Lucas J. J. (2001) Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease. J. Neurosci. 21, 8772-8781.
    • (2001) J. Neurosci. , vol.21 , pp. 8772-8781
    • Martin-Aparicio, E.1    Yamamoto, A.2    Hernandez, F.3    Hen, R.4    Avila, J.5    Lucas, J.J.6
  • 14
    • 0037075791 scopus 로고    scopus 로고
    • First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: Thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease
    • Martinez A., Alonso M., Castro A., Perez C. and Moreno F. J. (2002a) First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: Thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease. J. Med. Chem. 45, 1292-1299.
    • (2002) J. Med. Chem. , vol.45 , pp. 1292-1299
    • Martinez, A.1    Alonso, M.2    Castro, A.3    Perez, C.4    Moreno, F.J.5
  • 15
    • 0036273020 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation
    • Martinez A., Castro A., Dorronsoro I. and Alonso M. (2002b) Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation. Med. Res. Rev. 22, 373-384.
    • (2002) Med. Res. Rev. , vol.22 , pp. 373-384
    • Martinez, A.1    Castro, A.2    Dorronsoro, I.3    Alonso, M.4
  • 16
    • 0029751854 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 phosphorylation of different residues in the presence of different factors: Analysis on tau protein
    • Moreno F. J., Munoz-Montano J. R. and Avila J. (1996) Glycogen synthase kinase 3 phosphorylation of different residues in the presence of different factors: Analysis on tau protein. Mol. Cell. Biochem. 165, 47-54.
    • (1996) Mol. Cell. Biochem. , vol.165 , pp. 47-54
    • Moreno, F.J.1    Munoz-Montano, J.R.2    Avila, J.3
  • 17
    • 0031567583 scopus 로고    scopus 로고
    • Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons
    • Munoz-Montano J. R., Moreno F. J., Avila J. and Diaz-Nido J. (1997) Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons. FEBS Lett. 411, 183-188.
    • (1997) FEBS Lett. , vol.411 , pp. 183-188
    • Munoz-Montano, J.R.1    Moreno, F.J.2    Avila, J.3    Diaz-Nido, J.4
  • 18
    • 0032850599 scopus 로고    scopus 로고
    • Distribution of active glycogen synthase kinase-3 beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes
    • Pei J. J., Braak E., Braak H., Grundke-Iqbal I., Iqbal K., Winblad B. and Cowburn R. F. (1999) Distribution of active glycogen synthase kinase-3 beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes. J. Neuropathol. Exp. Neurol. 58, 1010-1019.
    • (1999) J. Neuropathol. Exp. Neurol. , vol.58 , pp. 1010-1019
    • Pei, J.J.1    Braak, E.2    Braak, H.3    Grundke-Iqbal, I.4    Iqbal, K.5    Winblad, B.6    Cowburn, R.F.7
  • 20
    • 0032491494 scopus 로고    scopus 로고
    • Genetic neurodegenerative diseases: The human illness and transgenic models
    • Price D. L., Sisodia S. S. and Borchelt D. R. (1998) Genetic neurodegenerative diseases: The human illness and transgenic models. Science 282, 1079-1083.
    • (1998) Science , vol.282 , pp. 1079-1083
    • Price, D.L.1    Sisodia, S.S.2    Borchelt, D.R.3
  • 22
    • 0027960448 scopus 로고
    • Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation
    • Stambolic V. and Woodgett J. R. (1994) Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation. Biochem. J. 303, 701-704.
    • (1994) Biochem. J. , vol.303 , pp. 701-704
    • Stambolic, V.1    Woodgett, J.R.2
  • 24
    • 0030044463 scopus 로고    scopus 로고
    • Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta
    • Takashima A., Noguchi K., Michel G., Mercken M., Hoshi M., Ishiguro K. and Imahori K. (1996) Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta. Neurosci. Lett. 203, 33-36.
    • (1996) Neurosci. Lett. , vol.203 , pp. 33-36
    • Takashima, A.1    Noguchi, K.2    Michel, G.3    Mercken, M.4    Hoshi, M.5    Ishiguro, K.6    Imahori, K.7
  • 25
    • 0034571171 scopus 로고    scopus 로고
    • Huntington's disease: The challenge for cell biologists
    • Tobin A. J. and Signer E. R. (2000) Huntington's disease: The challenge for cell biologists. Trends Cell Biol. 10, 531-536.
    • (2000) Trends Cell Biol. , vol.10 , pp. 531-536
    • Tobin, A.J.1    Signer, E.R.2
  • 26
    • 0029737421 scopus 로고    scopus 로고
    • Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II
    • Yamaguchi H., Ishiguro K., Uchida T., Takashima A., Lemere C. A. and Imahori K. (1996) Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II. Acta Neuropathol. (Berl) 92, 232-241.
    • (1996) Acta Neuropathol. (Berl) , vol.92 , pp. 232-241
    • Yamaguchi, H.1    Ishiguro, K.2    Uchida, T.3    Takashima, A.4    Lemere, C.A.5    Imahori, K.6
  • 27
    • 0034737299 scopus 로고    scopus 로고
    • Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
    • Yamamoto A., Lucas J. J. and Hen R. (2000) Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell 101, 57-66.
    • (2000) Cell , vol.101 , pp. 57-66
    • Yamamoto, A.1    Lucas, J.J.2    Hen, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.