Partial Purification and Characterization of γ-Secretase from Post-mortem Human Brain

Journal of Biological Chemistry

Volumn 278, Issue 27, 2003, Pages 24277-24284

  Farmery, Mark R ^a   Tjernberg, Lars O ^a   Pursglove, Sharon E ^a   Bergman, Anna ^a   Winblad, Bengt ^a   Näslund, Jan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; CHEMICAL BONDS; CYTOLOGY; DISEASES; MOLECULAR WEIGHT; NEUROLOGY; PATHOLOGY; PROTEINS; SOLUBILITY;

PATHOGENESIS; PROTEOLYSIS;

BRAIN;

AMYLOID BETA PROTEIN; FLUORESCENT DYE; GAMMA SECRETASE; NICASTRIN; PRESENILIN 1; PROTEIN PRECURSOR; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; PROTEINASE; SECRETASE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN TISSUE; CADAVER; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ISOLATION; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE MUTATION; HUMAN; HUMAN TISSUE; MEMBRANE BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SOLUBILIZATION; BIOASSAY; BRAIN; ENZYMOLOGY; IN VITRO STUDY; ISOLATION AND PURIFICATION; METABOLISM;

ANIMALIA;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; BIOLOGICAL ASSAY; BRAIN; CADAVER; ENDOPEPTIDASES; FLUORESCENT DYES; HUMANS;

EID: 0041589436     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211992200     Document Type: Article

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