A common enzyme connects Notch signaling and Alzheimer's disease

Genes and Development

Volumn 14, Issue 22, 2000, Pages 2799-2806

  Kopan, R ^a   Goate, A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA CATENIN; BETA SECRETASE; CHAPERONE; ENZYME PRECURSOR; GAMMA SECRETASE; LIGAND; MEMBRANE PROTEIN; MUTANT PROTEIN; NOTCH RECEPTOR; PRESENILIN 1; PRESENILIN 2; PROTEINASE; RECEPTOR PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL CELL; ARABIDOPSIS; AUTOSOMAL DOMINANT DISORDER; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; ENZYME MECHANISM; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INTRACELLULAR MEMBRANE; LIGAND BINDING; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVIEW; SACCHAROMYCES CEREVISIAE; SENILE PLAQUE; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; ENDOPEPTIDASES; MEMBRANE PROTEINS; PRESENILIN-1; PRESENILIN-2; RECEPTORS, CELL SURFACE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

ANIMALIA; ARABIDOPSIS; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MELANOGASTER; SACCHAROMYCES CEREVISIAE;

EID: 0034669031     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.836900     Document Type: Review

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