BACE1 is the major β-secretase for generation of Aβ peptides by neurons

Nature Neuroscience

Volumn 4, Issue 3, 2001, Pages 233-234

  Cai, Huaibin ^a   Wang, Yanshu ^a   McCarthy, Diane ^b   Wen, Hongjin ^a   Borchelt, David R ^a   Price, Donald L ^a   Wong, Philip C ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CIPHERGEN BIOSYSTEMS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SITE APP CLEAVING ENZYME 1; MESSENGER RNA; PROTEIN BACE1; UNCLASSIFIED DRUG;

ADENOVIRUS; ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN CORTEX; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; ENZYME DEFICIENCY; HIPPOCAMPUS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MOUSE; NEUROFIBRILLARY TANGLE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CELLS, CULTURED; ENDOPEPTIDASES; MICE; MICE, KNOCKOUT; NEURONS;

EID: 0035112647     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/85064     Document Type: Article

References (15)