메뉴 건너뛰기




Volumn 402, Issue 6761, 1999, Pages 537-540

Purification and cloning of amyloid precursor protein β-secretase from human brain

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

EID: 0033518251     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/990114     Document Type: Article
Times cited : (1518)

References (12)
  • 1
    • 0027459686 scopus 로고
    • Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide
    • Seubert, P. et al. Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide. Nature 361, 260-263 (1993).
    • (1993) Nature , vol.361 , pp. 260-263
    • Seubert, P.1
  • 2
    • 0026907151 scopus 로고
    • A pathogenic mutation for probably Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid
    • Mullan, M. et al. A pathogenic mutation for probably Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nature Genet. 1, 345-347 (1992).
    • (1992) Nature Genet. , vol.1 , pp. 345-347
    • Mullan, M.1
  • 3
    • 0026745610 scopus 로고
    • Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein secretion
    • Citron, M. et al. Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein secretion. Nature 360, 672-674 (1992).
    • (1992) Nature , vol.360 , pp. 672-674
    • Citron, M.1
  • 4
    • 0028817351 scopus 로고
    • Cell-type and amyloid protein-type specific inhibition of Ab release by bafilomycin A1, a selective inhibitor of vacuolar ATPases
    • Knops, J. et al. Cell-type and amyloid protein-type specific inhibition of Ab release by bafilomycin A1, a selective inhibitor of vacuolar ATPases. J. Biol. Chem. 270, 2419-2422 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 2419-2422
    • Knops, J.1
  • 5
    • 0017345848 scopus 로고
    • Subcellular distribution of rat brain cortex high-affinity, sodium-dependent, glycine transport sites
    • Valdes, F., Munoz, C., Feria-Velasco, A. & Orrego, F. Subcellular distribution of rat brain cortex high-affinity, sodium-dependent, glycine transport sites. Brain Res. 122, 95-112 (1977).
    • (1977) Brain Res. , vol.122 , pp. 95-112
    • Valdes, F.1    Munoz, C.2    Feria-Velasco, A.3    Orrego, F.4
  • 6
    • 0033049372 scopus 로고    scopus 로고
    • Subsite preference of pepstatin-insensitive carboxyl proteinases from bacteria
    • Narutaki, S., Dunn, B. M. & Oda, K. Subsite preference of pepstatin-insensitive carboxyl proteinases from bacteria. J. Biochem. (Tokyo) 125, 75-81 (1999).
    • (1999) J. Biochem. (Tokyo) , vol.125 , pp. 75-81
    • Narutaki, S.1    Dunn, B.M.2    Oda, K.3
  • 7
    • 0014211618 scopus 로고
    • On the size of the active site in proteinases. I. Papain
    • Schechter, I. & Berger, A. On the size of the active site in proteinases. I. Papain. Biochem. Biophys. Res. Commun. 27, 157-162 (1967).
    • (1967) Biochem. Biophys. Res. Commun. , vol.27 , pp. 157-162
    • Schechter, I.1    Berger, A.2
  • 8
    • 0003723604 scopus 로고
    • (eds Barrett, A. J. & Salvesen, G.) Elsevier Science, Amsterdam
    • Rich, D. H. in Proteinase Inhibitors (eds Barrett, A. J. & Salvesen, G.) (Elsevier Science, Amsterdam, 1986).
    • (1986) Proteinase Inhibitors
    • Rich, D.H.1
  • 9
    • 0031020909 scopus 로고    scopus 로고
    • 42 deposition in a transgenic mouse model of Alzheimer disease
    • 42 deposition in a transgenic mouse model of Alzheimer disease. Proc. Natl Acad. Sci, USA 94, 1550-1555 (1997).
    • (1997) Proc. Natl Acad. Sci, USA , vol.94 , pp. 1550-1555
    • Johnson-Wood, K.1
  • 10
    • 0033595706 scopus 로고    scopus 로고
    • β-secretase cleavage of the Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
    • Vassar, R. et al. β-secretase cleavage of the Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286, 735-741 (1999).
    • (1999) Science , vol.286 , pp. 735-741
    • Vassar, R.1
  • 11
    • 0031610694 scopus 로고    scopus 로고
    • The integration of medicinal chemistry, drug metabolism, and pharmaceutical research and development. the story of Crixivan, an HIV proteinase inhibitor
    • Lin, J. H., Ostovic, D. & Vacca, J. P. The integration of medicinal chemistry, drug metabolism, and pharmaceutical research and development. The story of Crixivan, an HIV proteinase inhibitor. Pharm. Biotechnol. 11, 233-255 (1998).
    • (1998) Pharm. Biotechnol. , vol.11 , pp. 233-255
    • Lin, J.H.1    Ostovic, D.2    Vacca, J.P.3
  • 12
    • 0025827025 scopus 로고
    • Isolation of Baculovirus-derived secreted and full-length β-amyloid precursor protein
    • Knops, J. et al. Isolation of Baculovirus-derived secreted and full-length β-amyloid precursor protein. J. Biol. Chem. 266, 7285-7290 (1991).
    • (1991) J. Biol. Chem. , vol.266 , pp. 7285-7290
    • Knops, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.