Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of β-catenin, a component of the presenilin protein complex

Nature Medicine

Volumn 5, Issue 2, 1999, Pages 164-169

  Nishimura, M ^a,b   Yu, G ^a,b   Levesque, G ^a,b   Zhang, D M ^a,b   Ruel, L ^c   Chen, F ^a,b   Milman, P ^a,b   Holmes, E ^a,b   Liang, Y ^a,b   Kawakai, T ^a,b   Jo, E ^a,b   Supala, A ^a,b   Rogaeva, E ^a,b   Xu, D M ^a,b   Janus, C ^a,b   Levesque, L ^a,b   Bi, Q ^a,b   Duthie, M ^a,b   Rozmahel, R ^d   Mattila, K ^e   Lannfelt, L ^e   Westaway, D ^a,b   Mount, H T J ^a,b   Woodgett, J ^c   Fraser, P E ^a,b   St George Hyslop, P ^a,b   more..

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; ARTICLE; GENE MUTATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INTRACELLULAR TRANSPORT; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; BETA CATENIN; BIOLOGICAL TRANSPORT; CELL LINE; CELL NUCLEUS; CYTOSKELETAL PROTEINS; HUMANS; MEMBRANE PROTEINS; MUTATION; NF-KAPPA B; PRESENILIN-1; PRESENILIN-2; PROTEIN BINDING; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 0032905727     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/5526     Document Type: Article

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