Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 24, 1997, Pages 13287-13292

  Sturchler Pierrat, Christine ^a   Abramowski, Dorothee ^a   Duke, Mairead ^a,c   Wiederhold, Karl Heinz ^a   Mistl, Claudia ^a   Rothacher, Sabin ^a   Ledermann, Birgit ^a   Bürki, Kurt ^a   Frey, Peter ^a   Paganetti, Paolo A ^a   Waridel, Caroline ^a   Calhoun, Michael E ^b   Jucker, Mathias ^b   Probst, Alphonse ^b   Staufenbiel, Matthias ^a   Sommer, Bernd ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c YRCR Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE MUTATION; GLIA CELL; HIPPOCAMPUS; INFLAMMATION; MOUSE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENILE PLAQUE; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; MICE; MICE, TRANSGENIC; MUTATION; NEOCORTEX; NEURITES; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); RECEPTORS, CHOLINERGIC; TAU PROTEINS;

ANIMALIA; MUS MUSCULUS;

EID: 0011444914     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.24.13287     Document Type: Article

References (42)

1. Probst, A., Langui, D. & Ulrich, J. (1991) Brain Pathol. 1, 229-239.
2. Selkoe, D. J. (1994) Annu. Rev. Cell Biol. 10, 373-403.
3. Yankner, B. A. (1996) Neuron 16, 921-932.
4. Goedert, M. (1993) Trends Neurosci. 16, 460-465.
5. Trojanowski, J. Q., Schmidt, M. L., Shin, R.-W., Bramblett, G. T., Rao, D. & Lee, V. M.-Y. (1993) Clin. Neurosci. 1, 184-191.
6. Tago, H., McGeer, P. L. & McGeer, E. G. (1978) Brain Res. 406, 363-369.
7. Geula, C. & Mesulam, M. (1989) Neuroscience 33, 469-481.
8. Mullan, M., Crawford, F., Axelman, K., Houlden, H., Lilius, L., Winblad, B. & Lannfelt, L. (1992) Nat. Genet. 1, 345-347.
9. Goate, A., Chartier-Harlin, M.-C., Mullan, M., Brown, J., Crawford, F. et al. (1991) Nature (London) 349, 704-706.
10. Citron, M., Oltersdorf, T., Haass, C., McConlogue, L., Hung, A. Y., Seubert, P., Vigo-Pelfrey, C., Lieberburg, I. & Selkoe, D. J. (1992) Nature (London) 360, 672-674.
11. Cai, X.-D., Golde, T. E. & Younkin, S. G. (1993) Science 259, 514-516.
12. Suzuki, N., Cheung, T. T., Cai, X.-D., Odaka, A., Otvos, L., Eckman, C., Golde, T. E. & Younkin, S. G. (1994) Science 264, 1336-1340.
13. Tamaoka, A., Odaka, A., Ishibashi, Y., Usami, M., Sahara, N., Suzuki, N., Nukina, N., Mizusawa, H., Shoji, S., Kanazawa, I. & Mori, H. (1994) J. Biol. Chem. 269, 32721-32724.
14. Quon, D., Wang, Y., Catalano, R., Scardina, J. M., Murakami, K. & Cordell, B. (1991) Nature (London) 352, 239-241.
15. Kammesheidt, A., Boyce, F. M., Spanoyannis, A. F., Cummings, B. J., Ortegon, M., Cotman, C., Vaught, J. L. & Neve, R. L. (1992) Proc. Natl. Acad. Sci. USA 89, 10857-10861.
16. Lamb, B. T., Sisodia, S. S., Lawler, A. M., Slunt, H. H., Kitt, C. A., Kearns, W. G., Pearson, P. L., Price, D. L. & Gearhart, J. D. (1993) Nat. Genet. 5, 22-30.
17. Mucke, L., Masliah, E., Johnson, W. B., Ruppe, M. D., Alford, M., Rockenstein, E. M., Forss-Petter, S., Pietropaolo, M., Mallory, M. & Abraham, C. R. (1994) Brain Res. 666, 151-167.
18. Higgins, L. S., Rodems, J. M., Catalano, R., Quon, D. & Cordell, B. (1995) Proc. Natl. Acad. Sci. USA 92, 4402-4406.
19. Andrä, K., Abramowski, D., Duke, M., Probst, A., Wiederhold, K.-H., Bürki, K., Goedert, M., Sommer, B. & Staufenbiel, M. (1996) Neurobiol. Aging 17, 183-190.
20. Games, D., Adams, D., Alessandrini, R., Barbour, R., Berthelette, P. et al. (1995) Nature (London) 373, 523-528.
21. Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F. & Cole, G. (1996) Science 274, 99-102.
22. Lüthi, A., van der Putten, H., Botteri, F. M., Mansuy, I. M., Meins, M., Frey, U., Sansig, G., Portet, C., Schmutz, M., Schröder, M., Nitsch, C., Laurent, J.-P. & Monard, D. (1997) J. Neurosci. 17, 4688-4699.
23. Sommer, B., Köhler, M., Sprengel, R. & Seeburg, P. H. (1991) Cell 67, 11-19.
24. Sola, C., Mengod, G., Probst, A. & Palacios, J. M. (1993) Neuroscience 53, 267-295.
25. Abramowski, D. & Staufenbiel, M. (1995) J. Neurochem. 65, 782-790.
26. Biernat, J., Mandelkow, E. M., Schroter, C., Lichtenberg-Kraag, B., Steiner, B., Berling, B., Meyer, H., Mercken, M., Vandermeeren, A., Goedert, M. & Mandelkow, E. (1992) EMBO J. 11, 1593-1597.
27. Goedert, M., Jakes, R. & Vanmechelen, E. (1995) Neurosci. Lett. 189, 167-169.
28. Frey, P., Sunderji, S. & Waridel, C. (1997) Alzheimer's Disease: Biology, Diagnosis and Therapeutics (Wiley, New York), pp. 449-455.
29. Probst, A., Tolnay, M., Langui, D., Goedert, M. & Spillantini, M. G. (1996) Acta Neuropathol. (Berlin) 92, 588-596.
30. Gallyas, F. (1971) Acta Morphol. Acad. Sci. Hung. 19, 1-8.
31. Hedreen, J. C., Bacon, S. J. & Price, D. L. (1985) J. Histochem. Cytochem. 33, 134-140.
32. Paganetti, P. A., Lis, M., Klafki, H.-W. & Staufenbiel, M. (1996) J. Neurosci. Res. 46, 283-293.
33. Greenberg, S. G., Davies, P., Schein, J. D. & Binder, L. I. (1992) J. Biol. Chem. 267, 564-569.
34. Goedert, M., Spillantini, M. G., Jakes, R., Rutherford, D. & Crowther, R. A. (1989) Neuron 3, 519-526.
35. Wolozin, B. L., Pruchnicki, A., Dickson, D. W. & Davies, P. (1986) Science 232, 648-650.
36. Mandybur, T. I. & Chiurazzi, B. A. (1990) Neurology 40, 635-639.
37. McGeer, P. L., Kawamata, T., Walker, D. G., Akiyama, H., Tooyama, I. & McGeer, E. G. (1993) Glia 1, 84-92.
38. Mesulam, M. M., Geula, C. H. & Moran, A. (1987) Ann. Neurol. 22, 683-691.
39. Busciglio, J., Lorenzo, A., Yeh, J. & Yankner, B. A. (1995) Neuron 14, 879-888.
40. Braak, E., Braak, H. & Mandelkow, E. M. (1994) Acta Neuropathol. 87, 554-567.
41. Carmel, G., Mager, E. M., Binder, L. I. & Kuret, J. (1996) J. Biol. Chem. 271, 32789-32795.
42. Masliah, E., Sisk, A., Mallory, M., Mucke, L., Schenk, D. & Games, D. (1996) J. Neurosci. 16, 5795-5811.